LOCUS       XM_006250049            4516 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ABL proto-oncogene 2, non-receptor
            tyrosine kinase (Abl2), transcript variant X7, mRNA.
ACCESSION   XM_006250049
VERSION     XM_006250049.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006250049.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006250049.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4516
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4516
                     /gene="Abl2"
                     /gene_synonym="Abll; Arg"
                     /note="ABL proto-oncogene 2, non-receptor tyrosine kinase;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 ESTs, 16 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 30 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:304883"
                     /db_xref="RGD:1590898"
     CDS             1016..4516
                     /gene="Abl2"
                     /gene_synonym="Abll; Arg"
                     /codon_start=1
                     /product="tyrosine-protein kinase ABL2 isoform X7"
                     /protein_id="XP_006250111.1"
                     /db_xref="GeneID:304883"
                     /db_xref="RGD:1590898"
                     /translation="MVLGPVQLPSSSHCRDQDTLLPCPGRDVSELPVAHVTDHFASCV
                     EDGFEGDKTGGSSPEVLHRPFGCDAESQALNEAIRWSSKENLLGATESDPNLFVALYD
                     FVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYH
                     GPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDSKVYVT
                     AESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMK
                     HKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLG
                     VCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIH
                     RDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIK
                     SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWK
                     WSPADRPSFAETHQAFETMFHDSSISEEVAEELGRTASSSSVVPYLPRLPLLPSKTRT
                     LKKQGENKENLDGGLDASEILASSSAPGFIRSTQASSGSPALPRKQRDKSPSSLLEDA
                     KETCFTRDRKGGFFSSFMKKRNAPMPPKRSSSFREMENQPHKKYELTGNFSPVASLQH
                     ADGFSFTPGQQESNLVPAKCYGGSFAQRNLCGDDDSGGGGGSGTAAGGWSGITGFFTP
                     RLIKKTLGLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQL
                     ERTVSTSSQPEENVDRANDMLPKKSEEGAAPARERPKAKLLPRGATALALRAPDPAIT
                     ESDCPGVGVAGVAAAPKGKERNGGTRLGVAGVPEDAEQPGWSSPAKAVAVLPTTHNHK
                     VPVLISPTLKHTAADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPP
                     VMRLLQHPSTCSDPEEEPTAPPAGQHTPDTQDGGKKAAPGPVPSSGKPGRPVMPPPQV
                     PLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKAALLECAGLLSSAITEPV
                     PHSQLVDTGHQLLHYCSGYVDCIPHTRNKFAFREAVSKLELSLQELQVSSTAAGVPGT
                     NPVLNNLLSCVQEISDVVQR"
ORIGIN      
        1 tatttaggtc atagtttcct ataattttta gtgtttcttt ttttcttctt ttttttagtg
       61 tttcttttat tgacctaaat agatggtata tagttagtac ttaataatca atgctgtgga
      121 cattcctgca gtacggttat agtgttatta cttgtaatac cttattgtaa gtgctattac
      181 tatggtgctg tggttgaggt tttttgagac aggttctgta gcacaggctg actttgaatt
      241 ttcagtcctc ctgcttccac gtagccaagc aagggtgtta aaaatgtgtg cccccatata
      301 ttctctgaat tattttcgtc gactgtactg tttagttatt cattacttac tttactagtt
      361 tgtctcataa atcattctga ttttaaggtc ttaaatttta tgtaactttc tgttctatac
      421 tcacaattag gcttttgcct ttccaagtgt cagcattcac aattcagcac tgtgccaggc
      481 cctttacctg tattgagcca cacaggccat ttgttaggga aggcaattgg ttgctctctg
      541 cttctgtctg tgtttatgag tcaccctgta gctatttctt tgacttcaga tttgtggttt
      601 cttgaactaa ctggagtgat gtaaaagatg agtctcttta ggcgtttcct gtcttttcca
      661 agtgttggtg gtgtactata aacaggcttc tcctaggaag aagcactgac cagtctcacc
      721 ctttatctcc ttgggattgg agtttctaga cttactgact ttagctgatt gtattattga
      781 atggttactg ttgtgtgact gaaatagcct atgtaccacc cagcccggat ccctgaggtt
      841 ttggagtgac tccaccctac tcaggtctcc acccctgtgg gtgaacttgc cctttgttcc
      901 ttctggctgc tgaatgtgtg agtaatgtcc cacgtgtatg gattgctggc cactgtggaa
      961 ttttacggct cctctattca gagcagtgta actttcaggc tgcttggcca aaggcatggt
     1021 tctgggacct gttcagctac catcaagcag tcactgtaga gaccaggaca ccttgcttcc
     1081 ctgcccaggc agggatgtgt ctgagttgcc tgtggcccac gtgacagatc actttgccag
     1141 ctgtgtggag gatggatttg agggagacaa gactggaggc agtagtccag aagttttgca
     1201 ccgccccttt ggttgtgacg ctgaatctca ggcactgaat gaagctatca ggtggagctc
     1261 caaggagaac ttgctgggcg ccactgagag cgaccctaat ctctttgttg cactttatga
     1321 ctttgtggca agtggcgata acacactcag catcaccaaa ggtgaaaagc tacgagtcct
     1381 tggttacaac caaaatggtg aatggagtga agttcgctcc aagaatgggc agggttgggt
     1441 gcccagcaac tacatcactc cagtcaacag cctggagaaa cattcctggt accatgggcc
     1501 tgtgtcccgc agtgcagcgg agtatctcct cagcagcctt atcaatggca gtttcctggt
     1561 gcgagagagt gagagcagcc ctgggcagct gtccatctct ctcagatatg agggacgtgt
     1621 gtatcactac aggatcaata ccaccacaga cagcaaggtg tacgtgactg ccgagagccg
     1681 cttcagcacc ttagcagagc ttgttcacca ccactccaca gtcgctgatg ggctagtgac
     1741 cacgctacat tacccagcac ccaagtgcaa caagccaacc gtctacggtg tgtctcctat
     1801 ccacgacaag tgggagatgg agcgcacaga tatcaccatg aagcacaagc ttgggggcgg
     1861 ccagtatgga gaggtttacg ttggcgtctg gaagaaatac agccttacag ttgctgtgaa
     1921 aacactgaag gaagatacca tggaggtaga ggagttcctg aaggaagctg cagtgatgaa
     1981 ggaaatcaag catcctaatt tagtacagct gttaggtgtg tgcaccctgg agccgccatt
     2041 ctacattgtg actgaataca tgccgtacgg gaatctgctc gattacctcc gggagtgcag
     2101 ccgtgaggag gtgactgcag tggtgctgct ttacatggcc actcagatct cctctgccat
     2161 ggagtacttg gagaagaaga acttcatcca cagagatctt gctgcacgga actgcctggt
     2221 gggggagaac catgtggtga aagtggctga ctttggtcta agtagactga tgactggaga
     2281 cacctacacc gctcatgctg gagccaaatt tcctattaaa tggacagcgc ctgagagtct
     2341 ggcctacaat accttttcaa ttaaatctga cgtttgggct tttggagtac tgttgtggga
     2401 aattgctacg tatggaatgt caccatatcc aggtattgac ctatctcaag tctatgacct
     2461 actggaaaaa ggatatcgaa tggagcagcc tgagggatgc ccccctaaag tgtatgaact
     2521 tatgagagca tgctggaagt ggagccctgc ggacaggccc tcttttgctg aaacccatca
     2581 agcttttgaa accatgttcc atgactccag catctctgaa gaggtagctg aggagcttgg
     2641 gagaactgcc tcctcctcat ctgtagttcc atacctgcct cgactgccac tacttccttc
     2701 caagacaagg accctgaaga agcaggggga gaacaaagag aacctagatg ggggccttga
     2761 tgcctccgag atcctggcct ccagctcagc accagggttc attagaagca cccaggcctc
     2821 cagtgggtcc ccagctctgc ctcgaaagca aagagataag tcacccagca gcctcttaga
     2881 agatgccaaa gagacatgct tcaccaggga caggaaggga ggcttcttca gctccttcat
     2941 gaaaaaaaga aatgccccca tgccccctaa gcgcagcagc tcttttcgag aaatggagaa
     3001 tcagccccac aagaaatatg aactcacggg taacttctca cctgttgctt ctctgcagca
     3061 tgctgatggg ttctctttca ctcccggcca gcaagagtcg aatctggtgc cagccaagtg
     3121 ctatgggggg agctttgcac agaggaacct ctgtggtgat gatgacagtg gtgggggtgg
     3181 gggtagtggc actgctgcgg gtgggtggtc tggtatcaca ggcttcttta cacctcgctt
     3241 aatcaaaaag acactgggct tgcgagcagg taaaccgaca gccagtgatg acacttccaa
     3301 gccttttcca aggtcaaact ctacatcttc catgtcctca gggctccccg agcaggatag
     3361 gatggcaatg acccttccca ggaactgcca gaggtccaaa ctccagctgg aaaggacagt
     3421 gtccacctct tctcaaccag aagagaatgt ggacagggct aatgacatgc ttccaaaaaa
     3481 atcagaggaa ggtgctgctc cagccaggga gagaccaaaa gccaaactat tgcccagagg
     3541 agccacggct cttgccctga gagcccctga tccagccatc actgagagtg actgtccagg
     3601 ggtaggggtg gctggagtgg cagctgcccc caaaggcaag gagaggaatg gtgggacgcg
     3661 gcttggagtc gctggagtcc cagaggacgc agagcagcca ggctggtctt ctccagccaa
     3721 ggctgtagct gtcctcccaa ccactcacaa ccacaaagtg ccagtcctta tctcacccac
     3781 tctgaaacac actgcagctg atgtgcagct cattggcaca gactctcagg ggaacaaatt
     3841 caagctctta tctgagcatc aggtcacatc ctctggagac aaggaccgac cccgacgggt
     3901 aaaaccaaag tgtgccccac ccccgccacc agtgatgaga ctactgcagc atccgtccac
     3961 atgctcagac cccgaggaag agccaactgc cccccctgca ggacagcaca ctccagacac
     4021 ccaggacgga ggaaaaaagg cagctccagg gccagtgccc agtagtggga aacctgggag
     4081 gccagtgatg cctccacctc aagtgccttt gcccacatct tccatctcgc cagccaaaat
     4141 ggccaatggc acagcaggta ctaaggtggc cctgaggaaa accaaacagg cagctgagaa
     4201 aatctcagct gacaaaatca gcaaagcggc cctgctggag tgtgccggcc tactgtccag
     4261 tgcaatcaca gaacctgtgc cccatagcca gctggtggac actgggcacc agctactcca
     4321 ctactgctca gggtatgtgg actgcatccc ccacactcgc aacaaatttg ccttccgaga
     4381 ggctgtgagc aaactggaac ttagcttaca ggagctgcag gtgtcttcca cagctgctgg
     4441 tgtgcctggg acaaaccctg tccttaataa cttattgtca tgtgtacagg aaattagtga
     4501 tgtggtgcag aggtag
//
