LOCUS       NM_001106275            2023 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus abhydrolase domain containing 2, acylglycerol
            lipase (Abhd2), mRNA.
ACCESSION   NM_001106275 XM_001064693 XM_214979
VERSION     NM_001106275.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2023)
  AUTHORS   M NK, V B S C T, G K V, B CS, Guntupalli S and J S B.
  TITLE     Molecular characterization of human ABHD2 as TAG lipase and ester
            hydrolase
  JOURNAL   Biosci Rep 36 (4), e00358 (2016)
   PUBMED   27247428
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2023)
  AUTHORS   Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith
            JF, Hill RZ, Bautista DM, Kirichok Y and Lishko PV.
  TITLE     Unconventional endocannabinoid signaling governs sperm activation
            via the sex hormone progesterone
  JOURNAL   Science 352 (6285), 555-559 (2016)
   PUBMED   26989199
REFERENCE   3  (bases 1 to 2023)
  AUTHORS   Miyata K, Oike Y, Hoshii T, Maekawa H, Ogawa H, Suda T, Araki K and
            Yamamura K.
  TITLE     Increase of smooth muscle cell migration and of intimal hyperplasia
            in mice lacking the alpha/beta hydrolase domain containing 2 gene
  JOURNAL   Biochem Biophys Res Commun 329 (1), 296-304 (2005)
   PUBMED   15721306
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001064693.1, XM_214979.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2023
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2023
                     /gene="Abhd2"
                     /note="abhydrolase domain containing 2, acylglycerol
                     lipase"
                     /db_xref="GeneID:293050"
                     /db_xref="RGD:1311389"
     exon            1..119
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            120..219
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            220..420
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     CDS             227..1504
                     /gene="Abhd2"
                     /EC_number="3.1.1.23"
                     /note="abhydrolase domain-containing protein 2"
                     /codon_start=1
                     /product="monoacylglycerol lipase ABHD2"
                     /protein_id="NP_001099745.1"
                     /db_xref="GeneID:293050"
                     /db_xref="RGD:1311389"
                     /translation="MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDL
                     YFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFIT
                     MSDGATSTFDLFEPLAEHCVGDDVTMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVL
                     NHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPQTQLVVVGFSLGGNIVCKYLG
                     ETQANQEKVLCCVSVCQGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALF
                     GDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIY
                     VPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTW
                     MDKLVVEYANAICQWERNKSQCSDTEQMEAELE"
     exon            421..596
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            597..764
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            765..948
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1041
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1152
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1222
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1307
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..2023
                     /gene="Abhd2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcgggag ctgcgctggc caggggttcc ggctgtattt ctatgagcgc agccggcagc
       61 tgcggagctg cgggaaccgg actccgggcg ggctggaccg cgggagtcac cgagcaaagc
      121 ttttaggtta ctttgaatac aagatcagat ctgattggcc cacctgtata cctcttcaag
      181 gaaagccggt cttctccgtg ggaggagtaa gcgacataga atcaagatga atgccatgtt
      241 ggagaccccc gagctccccg ccgtgtttga cggggtgaag ctggctgccg tagctgccgt
      301 tctctacgtc atcgtgcggt gtttgaacct gaagagccct actgcccctc ctgacctcta
      361 cttccaggac tccgggctct cacgtttcct gctcaaatcc tgtcctcttc tgaccaaaga
      421 atacattcca ccactaatct ggggaaagag tggacatatc cagacagcct tgtatgggaa
      481 gatggggagg gtgaggtcgc cacaccctta cgggcaccgc aagttcatca ccatgtcaga
      541 tggtgccact tctacattcg acctcttcga gcccctggct gagcactgtg ttggagatga
      601 cgtcaccatg gtcatctgtc ctggaattgc caatcacagc gagaagcagt atatccgaac
      661 ctttgttgac tatgcacaga aaaatggcta ccggtgcgca gtgctaaacc acctgggggc
      721 cctccccaac attgagctga cctccccacg catgttcacc tatggctgca cgtgggaatt
      781 tggagccatg gtgaactaca tcaagaagac atatccccag actcagctgg tcgtcgtggg
      841 cttcagcctg ggtggtaaca tcgtgtgcaa atacttgggg gagacgcagg ccaaccagga
      901 aaaggtccta tgctgtgtca gtgtttgcca ggggtacagt gcactgaggg cccaggagac
      961 cttcatgcag tgggaccagt gtcgccggtt ctacaacttc ctcatggctg acaacatgaa
     1021 gaagatcatc ctgtctcaca gacaagctct ctttggagac catgttaaga aaccccagag
     1081 cctggaggac acggacttga gccggctcta cacagcaacg tccctgatgc agatcgatga
     1141 caatgtgatg agaaagttcc atggctataa ctccctgaag gaatattatg aggaagagag
     1201 ctgcatgagg tacctgcaca ggatatacgt gcctctcatg ctggtcaatg ctgctgacga
     1261 ccccttggtg cacgaaagcc ttctaaccat tccaaagtct ctctcagaga aacgggaaaa
     1321 tgtcatgttt gtgctgcctc tgcatggggg ccacctgggc ttcttcgagg gctccgtgct
     1381 gttcccagag ccgctgacat ggatggataa gctggtggtg gagtacgcca atgccatttg
     1441 ccaatgggaa aggaataagt cccagtgctc agacacggag cagatggagg ccgagttaga
     1501 atgaggcctc cggactctgg cgtgctccag cggccctcct ctggaaccca cgctttgacg
     1561 gctgtttcag gtctctcagt gacctggatc tgacctcata ccatcagtgg ggggttaccc
     1621 atcatgcaac ctgtctaaag taggcggctc tccctgggag ctccaggcta tttttgtgct
     1681 tagttacggg ttttctccat tgcattgtta gccatggtga caagctacaa gattctcacc
     1741 cttctgtcca gtttcagtgt ctgattgctt tcacagccag taacatctag ttttcctact
     1801 aaggagctag tctgaactac agttttgctt tgccagtcaa aggcctttcc ctgagaacag
     1861 tgaaggatgt acgtcacttt gtgatggttg taggcgccct accagagtcc ccaccaagaa
     1921 gtcatatctc tagtgctgaa gacatcactc agcttgggag tccgaggacc tggggcttcc
     1981 tgggcctgaa ctttgcctgt gaagcaaagg aagttctctg atc
//
