LOCUS       NM_001006983            1517 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus abhydrolase domain containing 17A, depalmitoylase
            (Abhd17a), mRNA.
ACCESSION   NM_001006983 XM_216853
VERSION     NM_001006983.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Tortosa,E., Adolfs,Y., Fukata,M., Pasterkamp,R.J., Kapitein,L.C.
            and Hoogenraad,C.C.
  TITLE     Dynamic Palmitoylation Targets MAP6 to the Axon to Promote
            Microtubule Stabilization during Neuronal Polarization
  JOURNAL   Neuron 94 (4), 809-825 (2017)
   PUBMED   28521134
REFERENCE   2  (bases 1 to 1517)
  AUTHORS   Yokoi,N., Fukata,Y., Sekiya,A., Murakami,T., Kobayashi,K. and
            Fukata,M.
  TITLE     Identification of PSD-95 Depalmitoylating Enzymes
  JOURNAL   J Neurosci 36 (24), 6431-6444 (2016)
   PUBMED   27307232
REFERENCE   3  (bases 1 to 1517)
  AUTHORS   Lin,D.T. and Conibear,E.
  TITLE     ABHD17 proteins are novel protein depalmitoylases that regulate
            N-Ras palmitate turnover and subcellular localization
  JOURNAL   Elife 4, e11306 (2015)
   PUBMED   26701913
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1517)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083686.1.
            
            On Nov 22, 2004 this sequence version replaced XM_216853.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083686.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1517
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /note="abhydrolase domain containing 17A, depalmitoylase"
                     /db_xref="GeneID:299617"
                     /db_xref="RGD:1359682"
     exon            1..148
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /inference="alignment:Splign:2.1.0"
     exon            149..664
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /inference="alignment:Splign:2.1.0"
     CDS             333..1265
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /EC_number="3.1.2.22"
                     /note="abhydrolase domain-containing protein FAM108A;
                     family with sequence similarity 108, member A1;
                     abhydrolase domain-containing protein 17A; protein
                     ABHD17A"
                     /codon_start=1
                     /product="alpha/beta hydrolase domain-containing protein
                     17A"
                     /protein_id="NP_001006984.1"
                     /db_xref="GeneID:299617"
                     /db_xref="RGD:1359682"
                     /translation="MNGLSVSELCCLFCCPPCPGRIAAKLAFLPPEPTYSLVPEPEPG
                     PGGAGAAPSGPLRTSAATPGRWKIHLTERADFQYGQRELDTIEVFVTKSARANRIACM
                     YVRCVPGARYTVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEK
                     NLYADIDAAWQALRTRYGISPDSIILYGQSIGTVPTVDLASRYECAAVVLHSPLTSGM
                     RVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEP
                     LWVEGAGHNDIELYSQYLERLRRFISQELPSQRT"
     exon            665..859
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /inference="alignment:Splign:2.1.0"
     exon            860..1039
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1447
                     /gene="Abhd17a"
                     /gene_synonym="Fam108a; Fam108a1; RGD1359682; upf0227"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaaaactca cttccgcccg cggcggagct gcggtggtgg cggtgcagga ggctaggtcg
       61 gggcccccgg gggacagacg gacggacgca cgggcgggcg gccgggagcc atggagtgcg
      121 gcccccgggc cggcgggcgc gggcggcggg tgtcccactg tatggcatgg agacctgtgg
      181 ctgtgaggct cctgggggct cgccttggac cgcgatgggg ccgggctgcg gcctcctaac
      241 gggactgagg tgtgcagccc gcgagctgcc gctgcccgca tctcggagca cccccgcccc
      301 ccccctggcc cggcgcgggc ccggcgcccg ccatgaacgg cctgtcggtg agcgagctct
      361 gctgcctgtt ctgctgccca ccctgcccgg gccgcatcgc ggccaagctc gccttcctgc
      421 ctcccgagcc cacctactct ctggtacctg aacccgagcc ggggcccggc ggggccggcg
      481 ctgccccctc gggtcccctg cggacctcag cggccacccc cgggcgctgg aagatccacc
      541 tgacggagcg cgctgacttc cagtatggcc agcgcgagct ggacaccatt gaggtcttcg
      601 tgaccaagag cgcgcgcgcc aaccgcattg cctgcatgta tgtgcgctgt gtaccgggtg
      661 ccaggtacac agttctcttc tcgcatggca atgcggtgga cctgggccag atgtgcagct
      721 tttatgttgg cctgggcaca cgcatcggct gcaacatctt ctcttacgac tactctggct
      781 atggcatcag ctctggccgg ccctctgaga agaacctcta tgctgacatt gacgctgcct
      841 ggcaggccct gcgcaccagg tatggcatca gcccagacag tatcatcctg tatggccaga
      901 gcattggcac cgtgcccaca gtggatctgg cgtcacgtta tgagtgtgct gcagtggtcc
      961 tgcactcgcc tctcacctcc ggcatgcggg tggccttccc tgacaccaag aagacctact
     1021 gcttcgatgc tttccctaac atcgagaagg tgtcgaagat cacgtcaccg gtgctcatca
     1081 tccacggcac agaagacgag gtgatcgact tctcacacgg gctggcactg tatgagcgct
     1141 gtccaaaggc cgtggagccg ctgtgggtgg agggtgctgg gcacaacgac attgagctgt
     1201 atagtcaata cctggagcgc ctacgccgct tcatctccca ggagctgccc agccaacgca
     1261 cctaaccaag ccacagggac ctcagcagta cgcgggcctc ctgccggggc tgcatgtgac
     1321 ccggagccca ggacctgcct ggcacccagg ggccatgaac catgtgcagg cgacagaggt
     1381 ccctcttctc tcctcgggga agcaaagaga aggaaagagg gaaactaatt aaaggattaa
     1441 gattttaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaaaaa
//
