LOCUS       NM_212531               2022 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus abhydrolase domain containing 16A, phospholipase
            (Abhd16a), mRNA.
ACCESSION   NM_212531 XM_342091
VERSION     NM_212531.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Kamat,S.S., Camara,K., Parsons,W.H., Chen,D.H., Dix,M.M.,
            Bird,T.D., Howell,A.R. and Cravatt,B.F.
  TITLE     Immunomodulatory lysophosphatidylserines are regulated by ABHD16A
            and ABHD12 interplay
  JOURNAL   Nat Chem Biol 11 (2), 164-171 (2015)
   PUBMED   25580854
REFERENCE   2  (bases 1 to 2022)
  AUTHORS   Savinainen,J.R., Patel,J.Z., Parkkari,T., Navia-Paldanius,D.,
            Marjamaa,J.J., Laitinen,T., Nevalainen,T. and Laitinen,J.T.
  TITLE     Biochemical and pharmacological characterization of the human
            lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A)
  JOURNAL   PLoS One 9 (10), e109869 (2014)
   PUBMED   25290914
  REMARK    GeneRIF: BAT5 is a genuine lipase with preference for long-chain
            unsaturated monoacylglycerols, and could in this capacity regulate
            glycerolipid metabolism in vivo as well.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2022)
  AUTHORS   Ikegami,H., Kawaguchi,Y., Ueda,H., Fukuda,M., Takakawa,K.,
            Fujioka,Y., Fujisawa,T., Uchida,K. and Ogihara,T.
  TITLE     MHC-linked diabetogenic gene of the NOD mouse: molecular mapping of
            the 3' boundary of the diabetogenic region
  JOURNAL   Biochem Biophys Res Commun 192 (2), 677-682 (1993)
   PUBMED   8097912
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK653480.1 and BC091227.1.
            
            On Oct 1, 2009 this sequence version replaced NM_212531.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091227.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                CK653480.1         1-72
            73-2022             BC091227.1         1-1950
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2022
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /note="abhydrolase domain containing 16A, phospholipase"
                     /db_xref="GeneID:361796"
                     /db_xref="RGD:1303164"
     exon            1..228
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1773
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /EC_number="3.1.1.23"
                     /note="protein BAT5; abhydrolase domain-containing protein
                     16A; alpha/beta hydrolase domain-containing protein 16A;
                     protein ABHD16A; monoacylglycerol lipase ABHD16A;
                     HLA-B-associated transcript 5 homolog; HLA-B associated
                     transcript 5"
                     /codon_start=1
                     /product="phosphatidylserine lipase ABHD16A"
                     /protein_id="NP_997696.1"
                     /db_xref="GeneID:361796"
                     /db_xref="RGD:1303164"
                     /translation="MAKLLSCVLGPRLYKIYRERDTDRAATSVPETPTAVPAASSSSW
                     DSYYQPRALEKHADSILALASVFWSISYYSSPFAFFYLYRKGYLSLSKVVPFSHYAGT
                     LLVLLAGVACLRGIGRWTNPQYRQFITILEATHRNQSAENKRQLANYNFDFRSWPVDF
                     HWEEPSSRKGSRGGPSRRGVALLRPEPLHRGTADTFLNRVKKLPCQITSYLVAHTLGR
                     RMLYPGSVYLLQKALMPVLLQGQARLVEECNGRRAKLLACDGNEIDTMFVDRRGTAEP
                     QGQKLVICCEGNAGFYEVGCVSTPLEAGYSVLGWNHPGFAGSTGVPFPQNEANAMDVV
                     VQFAIHRLGFQPQDIVIYAWSIGGFTATWAAMSYPDISAVILDASFDDLVPLALKVMP
                     DSWRALVTRTVRQHLNLNNAEQLCRFQGPVLLVRRTKDEIITTTVPEDIMSNRGNDLL
                     LKLLQFRYPRVMTEEGLRAVRQWLEASSQLEEASIYSRWEVDEDWCVSVLRSYQAEHG
                     PDFPWSVGEDMSVDGRRQLALFLARKHLHNFEATHCTPLPAQHFQMPWCL"
     exon            229..285
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            286..352
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            353..439
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            440..525
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            526..599
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            600..722
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            723..837
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            838..939
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1003
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1053
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1177
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1282
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1346
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1403
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1466
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1543
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1642
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1689
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..1998
                     /gene="Abhd16a"
                     /gene_synonym="Bat5; NG26"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgctgacgtc acgcacgcac gcacgcagcg cccaggaggc tacgggcggg gccggcgggg
       61 acctgaggcc gagggacagc ggcccgagcc ggggctatgg cgaagctgct gagctgcgtc
      121 ctaggccccc ggctctacaa gatctaccgg gagagggaca cggaccgggc cgcgaccagc
      181 gtccccgaga ctcccactgc cgtccccgcc gcctcgtcca gctcctggga ttcgtattat
      241 cagcctcggg ccttggagaa acatgccgac agcatcctgg cactggcctc agtcttctgg
      301 tccatctctt attactcctc tcccttcgcc ttcttctacc tgtacaggaa aggttacttg
      361 agtttgtcca aagtggtgcc gttttctcac tatgccggga ccttgctggt actcctggca
      421 ggggtggcct gcctccgagg catcggccgc tggaccaacc cccagtaccg acagttcatc
      481 accatcttgg aagccacaca taggaaccag tctgcggaaa acaagagaca gctggccaac
      541 tataactttg acttcaggag ctggcccgtc gacttccact gggaggagcc cagcagccgg
      601 aaggggtccc gaggtggccc ttcccgcagg ggtgtggccc tgcttcgccc agagcctctg
      661 caccggggaa cagcagacac atttcttaac agagtcaaga agctgccctg tcaaatcacc
      721 agctatctgg tggcacacac cttggggcgc cggatgctgt acccaggctc cgtgtacctg
      781 ctccagaagg ccctcatgcc tgtgctgcta cagggccagg cccgactggt ggaagagtgt
      841 aatgggcgcc gtgcaaaact gctcgcctgt gacggcaatg agattgacac catgtttgtg
      901 gaccggcggg ggactgctga gccccagggg cagaagctgg tgatctgctg tgaggggaat
      961 gcgggattct acgaagtggg ctgtgtctcc acacccctag aagctggata ttctgtcctg
     1021 ggctggaatc atccaggctt tgctgggagc acgggggtac cattcccaca gaatgaggcc
     1081 aatgccatgg atgtggtggt tcagtttgcc atccaccgcc tgggcttcca gccccaggac
     1141 attgtcatct acgcctggtc cattggaggc ttcactgcca cgtgggcagc catgtcctac
     1201 ccagacatta gtgctgttat cctggatgcc tccttcgacg acttggtgcc cttggccttg
     1261 aaggtcatgc cggatagctg gcgagccctg gtgaccagga cagtgaggca gcacctcaac
     1321 ctcaacaacg cggagcagct gtgcaggttc cagggccctg tgctgctggt ccggagaacc
     1381 aaggatgaga tcatcaccac cacggttcct gaggacatca tgtccaacag aggcaatgac
     1441 ctcctgctga agctcctgca gttccggtac cctcgagtga tgacagagga ggggctcaga
     1501 gctgtgaggc agtggctgga ggcctcctcc cagctagagg aagcctccat ttatagtcgc
     1561 tgggaggtgg atgaggactg gtgtgtgtct gtgcttcgct cctaccaggc agagcatggg
     1621 cctgatttcc cctggagtgt gggggaagac atgagtgtag atggacggag gcaactggcg
     1681 ctgtttctgg ctcggaagca tctgcacaac tttgaggcca cacactgcac tccactccca
     1741 gcccagcact tccagatgcc ctggtgcctc taggcaccac atagactcct ctggaaggac
     1801 aagatgggag gagacacgag ggggctactt tgtgactctc ttgatgttgc tgtctatagt
     1861 ctggacagtg gggacatccc ctctggccac cttcctcctg cacgtttcct catctacatg
     1921 gaagctctca gctccccata cacacctgca ttgaatgagt gatttattcc taatgttaat
     1981 aaaaaggtat tttttctaaa aaaaaaaaaa aaaaaaaaaa aa
//
