LOCUS       NM_001123352            1251 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus abhydrolase domain containing 10, depalmitoylase
            (Abhd10), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001123352 XM_001064579
VERSION     NM_001123352.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1251)
  AUTHORS   Iwamura,A., Fukami,T., Higuchi,R., Nakajima,M. and Yokoi,T.
  TITLE     Human alpha/beta hydrolase domain containing 10 (ABHD10) is
            responsible enzyme for deglucuronidation of mycophenolic acid
            acyl-glucuronide in liver
  JOURNAL   J Biol Chem 287 (12), 9240-9249 (2012)
   PUBMED   22294686
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161919.1.
            
            On Apr 13, 2008 this sequence version replaced XM_001064579.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161919.1, CO568709.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1251
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..1251
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /note="abhydrolase domain containing 10, depalmitoylase"
                     /db_xref="GeneID:303953"
                     /db_xref="RGD:1308084"
     exon            1..120
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /inference="alignment:Splign:2.1.0"
     CDS             6..899
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /EC_number="3.1.2.22"
                     /EC_number="3.1.1.93"
                     /note="abhydrolase domain-containing protein 10,
                     mitochondrial; alpha/beta hydrolase domain-containing
                     protein 10, mitochondrial; mycophenolic acid
                     acyl-glucuronide esterase, mitochondrial; acyl-protein
                     thioesterase ABHD10; palmitoyl-protein thioesterase
                     ABHD10, mitochondrial"
                     /codon_start=1
                     /product="palmitoyl-protein thioesterase ABHD10,
                     mitochondrial precursor"
                     /protein_id="NP_001116824.1"
                     /db_xref="GeneID:303953"
                     /db_xref="RGD:1308084"
                     /translation="MAAWVPCRKWGWAAVSFGRHRGLIASLARKPPWAWWLSACRQKT
                     TLSFLKRPELPSLAYKRLKGKNPGIIFIPGYLSNMNGKKAVAIEEFCKSIGHAFIRFD
                     YSGVGSSDGNLAECSVGKWRKDVLSILDDIAEGPQILVGSSLGGWLMLHAAIARPEKV
                     IALIGIASATDGVVTQFHSLPVEMQKEIEMKGEWSLPSKYNKEGYYSIPYSFIKEAAH
                     HCLLHSPIPVTCPVRLLHGMKDEIVPWHRSLQVADRVVSPDVDVILRKHSDHRMKETA
                     DIHLLICTIDDLIDKLSTVTH"
     exon            121..304
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /inference="alignment:Splign:2.1.0"
     exon            305..416
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /inference="alignment:Splign:2.1.0"
     exon            417..554
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /inference="alignment:Splign:2.1.0"
     exon            555..1225
                     /gene="Abhd10"
                     /gene_synonym="RGD1308084"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagatggc tgcctgggta ccttgtcgga agtggggctg ggcggctgtg tccttcggcc
       61 ggcaccgagg cctgatcgcg tcacttgctc ggaagccccc atgggcatgg tggctctcag
      121 cttgcagaca aaagacaaca ctctctttcc ttaaacgacc agaacttcca agcctggctt
      181 ataagaggtt aaagggcaaa aacccaggaa ttatcttcat ccctggttat ctttctaaca
      241 tgaatggtaa aaaggcagta gcgattgagg agttttgcaa atctataggt cacgccttta
      301 tcaggtttga ctactctggg gttggaagct cagatggtaa cttagcagag tgctcagtgg
      361 ggaagtggag aaaggatgtt ctttccatcc ttgatgatat agccgaagga ccacagatac
      421 tggttggatc cagccttggt ggatggctca tgctgcatgc tgcaattgca cggccagaga
      481 aggtcatagc tcttattggg atagcttctg ctacagatgg agtggtgaca cagtttcact
      541 cacttcccgt tgagatgcaa aaggaaatag aaatgaaagg tgaatggtcc ttgccatcaa
      601 aatacaacaa agaaggctat tacagcattc cttacagttt cattaaagag gcggcgcatc
      661 actgcttgtt acacagcccc attcctgtga cgtgccctgt acggttgctc cacggcatga
      721 aggacgaaat agttccttgg cacagatccc tgcaggttgc cgaccgagta gtcagcccag
      781 atgtggatgt catcctccgg aagcacagtg atcacaggat gaaggagaca gcagatatcc
      841 atctgcttat ctgtactatt gatgacttga ttgacaagct ttcaactgtg actcactaga
      901 accgcacttg tgcttggtgt gcactctagt gcgtccagaa gattgaaagg atggtagtaa
      961 atcaaagacc cgggtacttc agggtttccc cttctagtat gtaaatatcc gatacgtatt
     1021 tatttaatga tgtgtttgca caagtacaca aattgggaga aaaatattag ctgctgtttg
     1081 gaaatttttg tcctcctttg atatttttcc cattaaaata gtacctattt tttttattaa
     1141 agagatgttt acctttctta tgtacacttt agctgtgcca gctctcaatt gtgttccttt
     1201 cttctacaat aaagcttgaa tagttaaaaa aaaaaaaaaa aaaaaaaaaa a
//
