LOCUS       XM_017592620            2722 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ATP binding cassette subfamily G
            member 2 (Abcg2), transcript variant X4, mRNA.
ACCESSION   XM_017592620
VERSION     XM_017592620.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017592620.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017592620.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2722
                     /gene="Abcg2"
                     /gene_synonym="Bcrp; BCRP1"
                     /note="ATP binding cassette subfamily G member 2; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 7 ESTs, 17 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     15 samples with support for all annotated introns"
                     /db_xref="GeneID:312382"
                     /db_xref="RGD:631345"
     CDS             281..2254
                     /gene="Abcg2"
                     /gene_synonym="Bcrp; BCRP1"
                     /codon_start=1
                     /product="broad substrate specificity ATP-binding cassette
                     transporter ABCG2 isoform X1"
                     /protein_id="XP_017448109.1"
                     /db_xref="GeneID:312382"
                     /db_xref="RGD:631345"
                     /translation="MSSSNDHVLVPMSQRNKNGLPGMSSRGARTLAEGDVLSFHHITY
                     RVKVKSGFLVRKTAEKEILSDINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPRGLS
                     GDVLINGAPQPANFKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNERI
                     NTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSS
                     TANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYF
                     ASAGYHCEPYNNPADFFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAE
                     FYINSTIYGETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIARRSFKNLLGNP
                     QASVAQLIVTVILGLIIGALYFGLKNDPTGMQNRAGVFFFLTTNQCFTSVSAVELFVV
                     EKKLFIHEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCILYFMLGLKRTVEAFFI
                     MMFTLIMVAYTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLS
                     WLQYFSIPRYGFTALQHNEFLGQEFCPGLNVTMNSTCVNSYTICTGNDYLINQGIDLS
                     PWGLWRNHVALACMIIIFLTIAYLKLLFLKKYS"
ORIGIN      
        1 ttttttacac atcaggagcc aggtttttgt tgtcattttt tatataattt gttggctcac
       61 tgctgctaat tttgagcttt tgccagtgag ttcctgtagc ttgtgcttcc tgatcctagt
      121 ttaagattca gttcctgaaa gtcattgcct atagtgtagt agaggaaaaa ctcttctccc
      181 ttctcaggtt gaatatttgg agacatgtga actgaactga gaagaaccag atcaattata
      241 actgcacatt gagagaaaac taaaggcata gatcctaaag atgtcttcta gtaatgacca
      301 cgtgttagta ccgatgtcac agagaaacaa gaacggcctt cctggaatga gctccagagg
      361 cgcgaggacg ctcgcagagg gagatgtgct aagttttcat cacatcacct atcgagtgaa
      421 agtgaagagt ggctttctag tccggaaaac agctgagaaa gaaatactat cagatatcaa
      481 tgggatcatg aaacctggtc ttaatgctat tctgggaccc acaggcggag gcaagtcttc
      541 gttgctagat gtcctagcag caaggaaaga cccacgggga ttatctggag atgttttgat
      601 aaacggggca cctcaacctg ccaatttcaa atgcagttca ggttatgtgg ttcaagatga
      661 cgttgtgatg ggcaccctga cagtgagaga aaacttacag ttctcagcag ctcttcgcct
      721 tccaaaagct atgaagacgc atgaaaaaaa tgaacggatt aacacgatca ttaaagagtt
      781 aggcctggac aaagtagcag attccaaggt tggaactcag tttacccgtg gtatctctgg
      841 aggagaaaga aaaaggacaa gcataggaat ggagctcatc actgaccctt ccatcctctt
      901 cctggatgag cccacaactg gtttggactc aagcacagca aatgctgtcc ttttgctcct
      961 gaaaaggatg tctaaacagg gccggaccat catcttctcc attcaccagc ctcggtattc
     1021 catctttaag ttgtttgaca gcctcacctt actggcttct gggaaactca tgtttcatgg
     1081 cccagcacag aaggccttgg agtactttgc atcagcaggt taccactgtg agccctacaa
     1141 caaccctgca gacttcttcc ttgacgtcat caacggagat tcttcggctg taatgttaaa
     1201 cagaggggaa caagaccatg aagcaaacaa gacagaagag ccttccaaga gagagaagcc
     1261 aataatagaa aatttagccg agttttatat caactccacc atctatggag aaacaaaagc
     1321 tgaattagat caacttccag tagctcagaa aaagaaagga tcatcagcct tcagagagcc
     1381 tgtatatgtt acctcgttct gtcatcagct cagatggatt gccaggcgtt catttaaaaa
     1441 cctgctcggg aatcctcaag cttctgtagc tcagttaatt gttacagtca tactgggact
     1501 gattattggt gccctttact ttggtctgaa aaatgatccc actggaatgc aaaatagagc
     1561 tggggttttc tttttcctga ctaccaacca gtgttttacc agtgtgtcag ctgtggagct
     1621 cttcgtagtg gagaagaaac tctttataca tgagtacatc agtggatatt acagagtatc
     1681 ttcttacttc tttggaaagc ttgtgtctga cttactacct atgaggttct tgccaagtgt
     1741 tatatacact tgtatattat acttcatgtt aggactgaag aggacggtgg aggctttttt
     1801 catcatgatg tttaccctta taatggtggc ttatacggcc agttccatgg ccctggccat
     1861 agccgcaggc caaagcgtag tgtctgtagc aacacttctc atgacgatct cttttgtgtt
     1921 tatgatgctc ttttctggcc tcttggtgaa tctcagaacc atcgggcctt ggctgtcctg
     1981 gcttcagtac tttagcattc ctcgatatgg cttcacagct ttgcagcata atgaattctt
     2041 gggacaagaa ttttgcccag gactcaatgt aactatgaac agcacctgtg ttaacagcta
     2101 tacaatatgt actggtaatg actacttgat aaatcagggc atcgatctgt caccttgggg
     2161 actgtggagg aatcatgtgg ccctggcttg catgatcatt atcttcctca caattgccta
     2221 cctgaaattg ttgtttctta agaagtattc ttaatttccc cttgaaagga ctattgatag
     2281 tactcctatt aaatatgggc actttgatta acatagtcag tgttcttttc ttcacagtta
     2341 ttctgacata caaaaatacc tagtactgaa aactaaggac atcatattaa gcccatcaat
     2401 tagtagtcat gggcagaaaa atccagtcag atttcctgat ttgaaaaggg gagacttgaa
     2461 ttctagatac tggtgatatg tcactaatct gtatttcatc atcttttaaa ctgatatgca
     2521 gaagccaggc atggtggcat ccctagtaat cctgacactt aggaggcaga aacagattgt
     2581 aggttgaggt ttgtttggac cctgtattaa aatgacagtg agtgaggcaa tcgggtaggg
     2641 gagtgacact tgaatagtct gcaagtttat ggcctgctgt tatttgataa ctaatgcata
     2701 tattaaagct gttttagaag tc
//
