LOCUS       XM_039092093            6231 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ATP binding cassette subfamily C
            member 6 (Abcc6), transcript variant X1, mRNA.
ACCESSION   XM_039092093
VERSION     XM_039092093.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039092093.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6231
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6231
                     /gene="Abcc6"
                     /gene_synonym="Mrp6"
                     /note="ATP binding cassette subfamily C member 6; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 8 ESTs, 2 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     4 samples with support for all annotated introns"
                     /db_xref="GeneID:81642"
                     /db_xref="RGD:620268"
     CDS             762..5009
                     /gene="Abcc6"
                     /gene_synonym="Mrp6"
                     /codon_start=1
                     /product="ATP-binding cassette sub-family C member 6
                     isoform X1"
                     /protein_id="XP_038948021.1"
                     /db_xref="GeneID:81642"
                     /db_xref="RGD:620268"
                     /translation="MQRPGSLPRAAFSLVWEDEESGTLPFCPPPSLVQSFATFLIHME
                     RKKGVRASGLLFGYWLLCCLVPAIDTVQQASAGSFRQEPLHHLATYLCLSLVVAELVL
                     SCLVDQPPFFSEDSKPLNPCPEAEASFPSKAMFWWASGLLWKGYRKLLGPKDLWSLER
                     ENSSEELVSQLEREWRRNFSELPGHKGHSGMGTPETEAFLQPERSQRGPLLRAIWRVF
                     RSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDLESSAWTGWLLAVLMFLSACLQTL
                     FEQQYMYRVKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDVQRLVES
                     ILHLNGLWLLFLWIIVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRSFHQEEQM
                     RQKASRARLTSSMLRTVRTIKSHGWECAFLERLLHIRGQELGALKTSAFLFSVSLVSF
                     QVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCLVQARV
                     SFDRLAAFLCLEEVDPNGMVLSPSRCSSKDRISIHNGTFAWSQESPPCLHGINLTVPQ
                     GCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCF
                     RQELDLPWLQEVLEACALGSDVASFPAGVHTPVGEQGMNLSGGQKQRLSLARAVYRRA
                     AVYLMDDPLAALDAHVSQEVFKQVIGPSGLLQGTTRILVTHTLHVLPQADQILVLANG
                     TIAEMGSYQDLLHRNGALVGLLDGARQPAGEGEGEAHAAATSDDLGGFSGGGTPTRRP
                     ERPRPSDAAPVKGSTSEAQMEPSLDDVEVTGLTAGEDSVQYGRVKSATYLSYLRAVGT
                     PLCTYTLFLFLCQQVASFCQGYWLSLWADDPVVDGKQMHSALRGSIFGLLGCLQAIGL
                     FASMAAVFLGGARASCLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDIVDVDIP
                     DKMRTLLTYAFGLLEVGLAVSMATPLAIVAILPLMLLYAGFQSLYVATCCQLRRLESA
                     SYSSVCSHLAETFQGSQVVRAFQAQGPFTAQHDALMDENQRISFPRLVADRWLAANLE
                     LLGNGLVFVAATCAVLSKAHLSAGLAGFSVSAALQVTQTLQWVVRSWTDLENSMVAVE
                     RVQDYVHTPKEAPWRLPSSAAQPLWPCGGQIEFRDFGLRHRPELPMAVQGVSLKIHAG
                     EKVGIVGRTGAGKSSLTWGLLRLQEATEGGIWIDGVPITDMGLHTLRSRITIIPQDPV
                     LFPGSLRMNLDLLQENTDEGIWAALETVQLKAFVTSLPGQLQYECSGQGDDLSVGQKQ
                     LLCLARALLRKTQILILDEATASVDPGTEIQMQAALERWFAQCTVLLIAHRLRSVMNC
                     ARVLVMDEGQVAESGSPAQLLAQKGLFYRLAQESGLA"
ORIGIN      
        1 gacacaggtg agaggctaag gcagactcgt gaagaaacgt ttcactgacg cagactcagg
       61 agaggatgtt ctgctcaagc aagcccgtga aaggtcgtgt gatgaaggat cctttgctga
      121 catgcatgta tggtctgcct tacactgctt agttgagctg catttgttgg gagaagtgca
      181 ccaaaaaaaa agcaaaaaca aaaacaaaca aacaaacaaa caaaaaaaca ccttctggtg
      241 gtgggctgca gtttcttgct gaggcaagac ctgtggagga cacgtgatgt ttggcgagag
      301 tatagaaatg actcagtgga cagtgtgatg gaggctcttt ataggtcgag ctgggtaacg
      361 cttgtctcaa tcttcgctga gagagacaca gctgagaatt taccctggcg ttcctcctgg
      421 tccctcctgc caaggctgag gcctggctgt ctctgccagg taatgtcacc actgctgatt
      481 cgtgtttgct atcccagact ctaccgaact ggactgctgg tgaatcagtg aaggtgtttt
      541 cgagtagatc gagttgccac tgctgactcc tgtgaactga actgcagatt tccaaacaac
      601 acagacgagc gtgtctgaac aggtgctcgg ctttgccctc atccttctct acaccttcaa
      661 cgcggccgtg cctctctgga ggatccaccg gggcatgccc caggccccag agcttctcat
      721 tcaccctacc gtgtggctca ccaccatggt aaccgctgcc tatgcagagg cctggctcgc
      781 tcccaagagc tgctttctca ctggtgtggg aggatgagga aagtgggacc ctccccttct
      841 gccctccacc ctctcttgtc cagagcttcg ccaccttcct gatccacatg gagagaaaga
      901 agggggtccg tgcatctggg ttgttgttcg ggtactggct gctctgctgc ctcgtgccag
      961 ccatcgacac tgtccagcag gcctccgcag ggagcttccg ccaggagccc ctccaccacc
     1021 tggccaccta cctgtgcttg tccctggtgg tggcagagct ggtgctgtct tgtctggtag
     1081 accagccacc cttcttctcg gaagactcca agccattgaa tccatgtcca gaggccgagg
     1141 cctcttttcc ctccaaggcc atgttctggt gggcctctgg actgctatgg aagggctaca
     1201 ggaaactgct ggggccaaaa gacctctggt cacttgagag agaaaactct tcagaagaac
     1261 ttgtttccca gctggaaaga gaatggagga ggaacttcag tgagctgccg gggcacaaag
     1321 ggcacagtgg tatggggacc cccgagacag aggccttcct gcagccagag aggagccagc
     1381 ggggcccgct gctcagggct atctggcgtg tgttccggtc cactttcctg ctggggaccc
     1441 tcagcctggt cattagcgat gccttcaggt ttgctgttcc caagctcctc agtctgtttc
     1501 tggagttcat gggcgacctc gagtcctcgg cttggacggg ctggctcctg gctgtgctga
     1561 tgttcttgtc ggcctgccta cagacactgt ttgaacagca gtacatgtac agagtcaagg
     1621 tcctgcagat gaggctgcga acagccatca ctggcctggt gtacagaaag gtcctggtcc
     1681 tgtccagtgg ttccagaaag tccagtgcag caggggacgt ggtcaacctg gtgtcagtgg
     1741 acgtacagcg gctggtcgag agcatcctcc acctcaacgg gctgtggctg ctcttcctgt
     1801 ggatcattgt gtgctttgtc tacctgtggc agctccttgg gccctctgcc ctcacagccg
     1861 ttgctgtctt cctgagcctt ctccccctga acttcttcat taccaagaag aggagcttcc
     1921 atcaggaaga acagatgagg cagaaggcct cccgagcacg gctcaccagc tccatgctca
     1981 gaactgtgag aaccatcaag tcccacggct gggagtgtgc cttcctggag cgactcctgc
     2041 atatccgggg ccaggagcta ggtgccctga agacctccgc cttcctcttc tctgtgtctc
     2101 tcgtgtcctt ccaagtgtct acatttctgg tggcgctggt tgtgtttgct gtccacaccc
     2161 tggtggcaga ggacaacgcc atggatgcgg agaaggcgtt tgtgacgctc acggtgctca
     2221 gcatccttaa caaagcccag gccttcctcc ccttctctgt gcactgcctc gttcaggctc
     2281 gggtgtcctt tgaccgccta gctgctttcc tgtgcctgga agaagtagac cccaatggca
     2341 tggtcttgag tccctccaga tgctcctcga aggatcgaat ttctatacac aatggcacct
     2401 tcgcttggtc ccaggagagc ccgccctgcc tgcacgggat caacctcacc gtgccccagg
     2461 gctgtctgct ggctgttgtg ggtccagtgg gggctggaaa gtcctccctg ctgtctgccc
     2521 tgcttgggga gctgttgaag gtagaagggt ctgtgagcat tgagggttcc gtggcctacg
     2581 tgcctcagga ggcttgggtc cagaatacct ctgtggtgga gaatgtgtgc ttcaggcagg
     2641 agctggatct gccatggttg caggaagttc tagaagcctg tgccttgggg tctgatgtgg
     2701 ccagcttccc tgcaggagtt cacaccccag taggggagca gggcatgaat ctttctgggg
     2761 gccagaagca gcggctgagc ttggctcggg ctgtgtacag aagggctgct gtgtacctga
     2821 tggatgaccc cctagcagcc ctggatgcgc atgtcagcca ggaagtcttc aaacaggtca
     2881 ttggccccag tggacttctc caaggtacga ctcggatcct tgtaacacac acgctgcatg
     2941 tcctgcccca agctgaccag atcctggtgc tggccaatgg gaccatcgca gagatgggct
     3001 cctaccaaga ccttctgcat aggaacggag ccctggtggg tcttctggat ggagccagac
     3061 agcctgcagg cgaaggagaa ggagaagcac atgctgcagc caccagtgat gaccttggag
     3121 gcttttctgg aggtgggacg cccacgcgca gaccagagag gcccagaccc agtgacgcag
     3181 cccctgtgaa gggcagtact tcagaggcac agatggagcc ttctctggat gacgttgagg
     3241 tcactggact gacagcagga gaggacagtg tgcagtatgg ccgggtgaag agcgccacat
     3301 acctgagcta cctgcgggcg gtgggcacac cgctctgcac ctacaccctg ttcctcttcc
     3361 tctgccagca agtggcgtcc ttctgccaag gctactggct gagcctctgg gccgacgacc
     3421 cggtcgtgga tgggaagcag atgcattcag ccctgcgtgg ctccatcttt ggactccttg
     3481 gctgtctgca agccatcgga ctgtttgcct ccatggctgc ggtgttcctg ggtggagccc
     3541 gagcttcatg cctgcttttc cggagcctcc tctgggacgt ggctcgctct cccattggct
     3601 tctttgagcg cacaccagtc gggaacctgc tgaaccgttt ttccaaggag acggacatag
     3661 tggatgtgga catcccagac aagatgagga ccctgctgac ctatgccttt ggactcctgg
     3721 aggttggcct ggcagtgtcg atggccacac cactggctat tgtggccatc ctacctctta
     3781 tgctccttta tgctgggttt cagagcctct acgtggccac atgttgccag ctgagacgcc
     3841 tggagtcggc cagttactcc tcagtgtgtt cccatctggc tgagaccttc cagggcagtc
     3901 aggtggtcag ggccttccag gcccaggggc ccttcacagc tcagcacgat gccctcatgg
     3961 atgagaacca gaggatcagt ttcccgaggc tggtggctga caggtggctg gctgccaacc
     4021 tggagctcct ggggaatggc ctggtgtttg tggccgctac atgtgctgtg ctgagcaagg
     4081 ctcacctgag tgctggcctc gcgggcttct cggtttctgc tgccctccag gtaacacaga
     4141 ctctgcagtg ggtggtccgc agctggacag atctggagaa cagcatggtg gccgtggagc
     4201 gagtacagga ctacgttcac acccccaagg aggctccctg gaggctgccc tcctctgcag
     4261 cccagcctct ctggccctgt gggggacaga ttgagttccg agactttggg ctcagacacc
     4321 gaccagagct gcccatggct gtgcagggtg tgtccctgaa gatccatgca ggggagaagg
     4381 tgggcatcgt gggcaggaca ggggccggga agtcctccct gacttggggc ctgctgcggc
     4441 ttcaggaggc cactgagggt ggtatttgga tcgatggggt ccccatcacc gacatggggc
     4501 tgcacacact gcggtccaga atcaccatca tccctcagga ccctgtcctg ttcccgggct
     4561 cgctgcggat gaacctggac ctgcttcagg agaacacaga tgagggcatc tgggcagcgc
     4621 tggagacggt gcagctcaag gccttcgtga ccagcctgcc tggccagctg cagtatgagt
     4681 gctcaggcca gggagatgac ctgagtgtgg gtcagaagca gctcctgtgt ctggcacgtg
     4741 cccttctccg gaaaacccag atcctcatcc tggatgaagc cactgcctcc gtggacccag
     4801 ggacggagat acagatgcag gcggccctcg agcgctggtt tgcacagtgt acagtgctgc
     4861 tcattgctca ccgcctgcgc tccgtgatga actgcgccag ggttctagtc atggatgagg
     4921 ggcaggtggc agagagtggc agtccagcac agctgctggc ccagaaaggc ctgttttaca
     4981 ggctagccca ggagtcgggc ctagcctgag tcaggactct tcccaaacct cctggagcca
     5041 gccacagagc ctgcagtagc tggagatgcc agagactcag gggccacatg atgcccaatc
     5101 taaactcctt tttgggagga agatagcaga gagagtgaca gagtattgga ataccagacc
     5161 cagaagaacc cagcatgccc aggttggctt gagcaaggcc acacccaccc caggccaaaa
     5221 agaacagtga ctctcagccc aagctgtcta cttcaaggcc atacccaccc caggccattc
     5281 aggttggatg ccctggaccg gggtgatggc gtgcacatat cccctaactc cttattttga
     5341 ggtcattgta gagttcactc acagttttaa gaagccacat ggagagaagc cgcaaaccct
     5401 ctgccctgtt tattccgggg gtgacacctt gtccaaccct aggacaagat gaagcatcac
     5461 actgactccg actgacttgt ctttacctct gctgcgtgtg catcagtgtt tggactccgt
     5521 gctttgtgct ctcattggtt tttgagacag gatttcacat agcccaggct ggccctgaac
     5581 tcactttgtt gctgaggatg gccttgaaca tctgatgctc ctgccttccc tcccaagtgc
     5641 tgggattatg gcctgtgtca ccacgccctg tgtgggggtc tcaaacaagg ctttgtgtgt
     5701 gcttgacagg cactcactct aaaaactgtg ttacagcccc ggctctggat tcggttctac
     5761 tcctgtttaa aattgtagtg gtgaagggtc tcttgctcaa actggcctca aactcgagat
     5821 gctcctgtct cggtctccag agtgctggaa tgacagacgt gtgccactac acctgccttg
     5881 actcaccaca gctaagtagt gacatcccca tgggccaggg ctggtgagtc ccgtgcgtga
     5941 cagtgtgctg agcagtaccc ttcgcttctg ctcagagatg cccttctaaa gctgtggcaa
     6001 agagatttcc acacactgcc gtgccccccc aggactgcat catgaattga tccgccctaa
     6061 tagcacccat gactccctga gcagtgatat gttgggttca ggagaggatt cctgcttgct
     6121 tcttggacag ggcttgctct tccctcgacc ctgaggcttc tctgattggc tacccttaat
     6181 aaaggattta cgggatttcc tttcagctca gaggattccc ctttgcttgt a
//
