LOCUS       NM_199377               4541 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ATP binding cassette subfamily C member 12
            (Abcc12), mRNA.
ACCESSION   NM_199377 XM_226344
VERSION     NM_199377.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4541)
  AUTHORS   Shimizu,H., Taniguchi,H., Hippo,Y., Hayashizaki,Y., Aburatani,H.
            and Ishikawa,T.
  TITLE     Characterization of the mouse Abcc12 gene and its transcript
            encoding an ATP-binding cassette transporter, an orthologue of
            human ABCC12
  JOURNAL   Gene 310, 17-28 (2003)
   PUBMED   12801629
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY188179.1.
            
            On Jan 11, 2004 this sequence version replaced XM_226344.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY188179.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4541
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     gene            1..4541
                     /gene="Abcc12"
                     /note="ATP binding cassette subfamily C member 12"
                     /db_xref="GeneID:291923"
                     /db_xref="RGD:735100"
     exon            1..21
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            22..190
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..4172
                     /gene="Abcc12"
                     /note="multidrug resistance-associated protein 9;
                     ATP-binding cassette transporter sub-family C member 12;
                     ATP-binding cassette, sub-family C (CFTR/MRP), member 12;
                     ATP-binding cassette, subfamily C (CFTR/MRP), member 12"
                     /codon_start=1
                     /product="ATP-binding cassette sub-family C member 12"
                     /protein_id="NP_955409.1"
                     /db_xref="GeneID:291923"
                     /db_xref="RGD:735100"
                     /translation="MVGEDPYLISDLDRRGRRRSFAERYDPSLKTMIPMRPYARLAPN
                     PVDDAGLLSFATFSWLTPVMIRSYKHTLTVDTLPPLSPYDSSDVNAKRLQILWDEEIE
                     RVGPERASLGRVVWKFQRTRVLMDVVANILCIIMAALGPTVLIHQILQHVTNISSGHI
                     GISICLCLALFATEFTKVLFRALAWAINYRTAIRLKVALSTLIFKNLLSFKTLTHISA
                     GEVLNVLSSDSYSLFEAALFCPLPATIPILMVVCAVYAFFILGSTALVGICVYLIFIP
                     IQMFMAKLNSAFRRSAISVTDKRVQTMNEFLTCIKLIKMYAWEKSFMNTIHDIRKREK
                     KLLEKAGYVQSGNSALAPIVSTIAIVSTFTCHIFLKRTLTAPVAFSVIAMFNVMKFSI
                     AILPFSVKAVAEASVSLRRMKKILVAKSPPSYITQPEDPDTILLLANATLTWEQEINR
                     KRGPSKTQDQRRHVFKKQRAELYSEQSLSDQGVASPERQSGSPKSVLHNISFVVRKGK
                     VLGICGNVGSGKSSLISALLGQMQLQKGVVAASGPLAYVSQQAWIFHGNVRENILFGE
                     KYNHQRYQHTVHVCGLQKDLNSLPYGDLTEIGERGVNLSGGQRQRISLARAVYANRQL
                     YLLDDPLSAVDAHVGKHVFEECIKKTLKGKTVVLVTHQLQFLESCDEVILLEDGEICE
                     KGTHKELMEERGRYAKLIHNLRGLQFKDPEHIYNVAMVETLKESQAQRDEDAVLASGD
                     ERDEGKEPETEEFVDIKAPVHQLIQIESPQEGIVTWKTYHTYIKASGGYLVSFLVLCL
                     FFLMMGSSAFSTWWLGLWLDSGSQVICAPQSNETACNVNQTLQDTKHHMYQLVYIASM
                     MSVLTFGIIKGFTFTNTTLMASSSLHNRVFNKIVSSPMSFFDTTPTGRLMNRFSKDMD
                     ELDVRLPFHAENFLQQFSMVVFILVIMAASFPVVLVVLAGLAILFFILLRIFHRGVQE
                     LKQVENISRSPWFSHITSSMQGLGVIHAYDKKDDCISKFKALNDENSSHLLYFNCALR
                     WFALRMDILMNIVTFVVALLVTLSFSSISASSKGLSLSYIIQLSGLLQVCVRTGTETQ
                     AKFTSAELMREYISTCVPEHTQSFKVGTCPKDWPSRGEITFKDYRMRYRDNTPLVLDG
                     LNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPASGTIFIDEVDICTVGLEELRTKL
                     TMIPQDPVLFVGTVRYNLDPLGSHTDEMLWHVLERTFMRDTIMKLPEKLQAEVTENGE
                     NFSVGERQLLCMARALLRNSKIILLDEATASMDSKTDTLVQSTIKEAFKSCTVLTIAH
                     RLNTVLNCDLVLVMENGKVIEFDKPEVLAEKPDSAFAMLLAAEVGL"
     exon            191..346
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            347..494
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            495..731
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            732..905
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1053
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1202
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1203..1310
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1589
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1661
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1786
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1859
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..2063
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2198
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2274
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2275..2343
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2344..2433
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2434..2537
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2538..2735
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2736..2962
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            2963..3100
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3101..3287
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3377
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3378..3567
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3568..3727
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3728..3806
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3807..3920
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            3921..4085
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
     exon            4086..4541
                     /gene="Abcc12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccacagag gaggaagcta gagtgaacgt gtctcaaagc caggagtcca gggctccaga
       61 acaccatcaa gatggtgggc gaagacccgt accttatctc agacctggat cgcagaggcc
      121 gtcggagatc ctttgccgag agatatgatc ccagcctgaa aaccatgatc ccaatgcgac
      181 cctatgcaag gctggcaccc aatcctgtgg atgatgcggg gctgctgtcc ttcgccacgt
      241 tttcctggct cacacctgtg atgattcgaa gttacaagca cacgctgacc gtggacaccc
      301 tgcctccact atctccttac gactcatcgg atgtcaatgc caagagactc caaatccttt
      361 gggatgaaga aatagaaagg gtagggcccg agcgggcctc tttgggccgt gtggtttgga
      421 aattccagag gacccgtgtt ctgatggatg ttgtagccaa cattctctgc atcatcatgg
      481 cagccttagg gccgacagtt ctcattcacc aaatcctcca gcacgttacc aacatctcct
      541 ccggacacat cgggatcagc atctgcttgt gtctggccct ttttgccacc gagtttacca
      601 aagtcctctt tcgggccctt gcctgggcca taaattaccg cacagcgatt cgactgaagg
      661 tggccctgtc cacgctaatt ttcaaaaatc tgttgtcctt caagacatta acccacatct
      721 ctgcaggcga ggtactcaat gtactatcga gtgatagtta ttccttgttt gaggctgcct
      781 tgttttgtcc tttgccagcc accatcccga tcctaatggt cgtttgtgcc gtgtatgcct
      841 ttttcattct ggggtccacc gctcttgttg ggatatgcgt gtatctcata ttcatcccga
      901 tccagatgtt tatggccaaa ctcaactcag ctttccgaag atcagcaatt tcagtgacag
      961 acaagcgggt tcagacaatg aatgagtttc tgacctgcat caaactgatt aaaatgtatg
     1021 cctgggagaa atcttttatg aacaccattc acgacataag aaagagagag aaaaaattac
     1081 tggaaaaggc tggatacgtc caaagtggga actcagccct ggctcccata gtgtctacca
     1141 tagccattgt gtctactttc acctgccaca ttttcctgaa acgcacactc actgcccctg
     1201 tggcatttag tgtgattgcc atgtttaatg taatgaagtt ttcaattgca atcttgcctt
     1261 tctcggtcaa agcagtggcc gaagccagtg tctctctaag gagaatgaag aaaattcttg
     1321 tagctaaaag tcccccatcc tacatcaccc aaccagaaga cccagatact atcttgcttt
     1381 tagcaaatgc caccctgaca tgggaacaag aaatcaacag gaaaagaggc ccatcgaaga
     1441 cacaagatca gagaaggcac gttttcaaga aacagagggc agagctatac agtgagcaaa
     1501 gtctctcaga tcagggagtt gccagcccag agcggcaaag tggcagcccc aagtcagtac
     1561 tacacaacat cagctttgtg gtgagaaagg gaaaggtctt ggggatatgc gggaatgttg
     1621 gaagcgggaa gagttccctc atttctgctc ttctagggca gatgcagtta cagaaagggg
     1681 tcgtggctgc cagtggacct ttggcttatg tttctcagca agcttggatc ttccacggaa
     1741 atgtgaggga gaacatcctg tttggagaga agtacaacca ccaaaggtac caacacacgg
     1801 ttcatgtctg tgggctccag aaggatttga acagcctccc ttatggagac ctgactgaga
     1861 ttggggagcg gggtgtgaac ctctccgggg gacagaggca gaggatcagc ctggcccggg
     1921 ctgtgtacgc caaccgtcag ctctacctgc tggatgaccc gctctcggca gtggatgccc
     1981 atgtggggaa gcacgtcttt gaagaatgca ttaaaaagac actcaagggg aagactgtgg
     2041 tgctggttac ccaccagctg cagttcctgg agtcttgcga tgaggtcatt ctgttagaag
     2101 atggagagat ctgtgaaaag ggcacccaca aggagttgat ggaagagaga ggccgctatg
     2161 caaagctgat ccacaacctc aggggactgc aattcaagga tccagagcac atttacaatg
     2221 tagccatggt ggagaccctg aaggagagcc aagctcaaag ggatgaagac gctgtcttgg
     2281 cttcaggaga tgagagagat gaaggaaaag aacccgagac agaagaattt gtggacataa
     2341 aagctcccgt gcaccagctc atccagattg aatcccccca agaaggaatc gtgacctgga
     2401 aaacatatca cacgtatatt aaagcttctg gagggtacct ggtctccttc ctggttttgt
     2461 gtctcttctt cctgatgatg ggcagctctg ccttcagcac ctggtggctg gggctctggt
     2521 tggacagtgg ctcccaggtc atctgtgcac cccagagcaa tgagacagcc tgcaacgtta
     2581 accagacgct gcaggacacc aaacaccaca tgtaccagtt ggtttacata gcaagcatga
     2641 tgtctgtgct gacgtttggc atcatcaaag gcttcacctt caccaacacg acactgatgg
     2701 cgtcctcctc cctccacaac agagtgttta acaagatcgt cagcagccca atgagcttct
     2761 ttgacacgac tcccacaggc cggctaatga accgcttttc taaagatatg gatgagctag
     2821 atgtgaggct gccatttcac gctgagaatt ttttgcagca gttttctatg gtggtgttta
     2881 ttctggtgat tatggctgcc tcgtttcctg ttgtcctcgt ggtgctggct ggcctggcta
     2941 ttctcttctt catcctttta cgcattttcc atcgaggggt gcaggagctc aagcaggtgg
     3001 agaacatcag ccggtcccct tggttctctc acatcacctc ctccatgcag ggtctgggtg
     3061 tcatccatgc ctacgacaaa aaggacgatt gcatcagcaa gtttaaggcg ctcaatgatg
     3121 aaaactccag ccacctcttg tactttaact gtgcactcag gtggtttgct ctcagaatgg
     3181 acatcctcat gaacatcgtc acctttgtcg tggccttgct ggtgaccctg agcttttctt
     3241 caatcagtgc ttcatccaaa ggcttgtccc tgtcttacat catccagctc agtggactgc
     3301 ttcaagtgtg tgtgcgaaca ggaacagaga cccaagccaa gttcacctct gcagagctaa
     3361 tgagggagta catttcgacc tgtgtccctg aacacactca atccttcaaa gtggggacct
     3421 gtcccaaaga ctggccgagc cgtggggaga taactttcaa ggactatcgg atgagataca
     3481 gagacaacac ccctctcgtt ctcgatgggt tgaacctgaa catccaaagc gggcagacag
     3541 ttgggattgt gggaagaacg ggctctggta aatcatcact gggcatggcc ctgtttcgtc
     3601 tggtggaacc agcctctggc accatcttca ttgacgaggt ggatatctgc actgtgggtc
     3661 tggaagagct ccgaaccaag ctgaccatga tcccccagga tcctgtcctg tttgtaggta
     3721 cagtaaggta caacttggat cccttgggga gtcacaccga cgagatgctc tggcatgttt
     3781 tggagagaac attcatgaga gacacaataa tgaaactccc agagaaatta caggcagaag
     3841 tcacagaaaa cggggaaaac ttctcagtag gagaacgcca gctgctttgt atggcccggg
     3901 cacttctccg taattcaaaa atcattctcc ttgatgaagc tactgcctcc atggattcca
     3961 agacggacac ccttgttcag agcaccataa aagaggcctt caaaagctgc acagtgctga
     4021 ccatcgctca tcgcctaaac actgttctca actgtgacct tgtcctggtc atggaaaatg
     4081 ggaaggtgat tgagtttgac aagcctgaag tcctcgctga gaagcctgac tctgcatttg
     4141 cgatgttact agctgcagaa gttggactgt aaaggtcccg tggttggttt gagaggagac
     4201 aatggatgtg tgagaggaga agcctgaagg tagagtcaag cagccctggc cacagcccct
     4261 cccacccatg gagcacaggg tgagctgggg ctgagatgtg tcccttgccc ttctggtcac
     4321 ctcccttggc agactcaggg ttagttctgg atggtgaaga atccagacaa agctgggggg
     4381 ttggaagctg cctctcactt ctgaaaaccc caagggtcct catggtcctc atcaatacta
     4441 cataatgctc gagaatggga acattctaac tttccgtcca aaagcagtaa aagcgaatga
     4501 gatggaaaat gcccaaggct ggaggtaaca gcgctcctcg c
//
