LOCUS       NP_955409               1366 aa            linear   ROD 03-APR-2024
DEFINITION  ATP-binding cassette sub-family C member 12 [Rattus norvegicus].
ACCESSION   NP_955409 XP_226344
VERSION     NP_955409.1
DBSOURCE    REFSEQ: accession NM_199377.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1366)
  AUTHORS   Shimizu,H., Taniguchi,H., Hippo,Y., Hayashizaki,Y., Aburatani,H.
            and Ishikawa,T.
  TITLE     Characterization of the mouse Abcc12 gene and its transcript
            encoding an ATP-binding cassette transporter, an orthologue of
            human ABCC12
  JOURNAL   Gene 310, 17-28 (2003)
   PUBMED   12801629
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY188179.1.
            
            On Jan 11, 2004 this sequence version replaced XP_226344.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY188179.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     Protein         1..1366
                     /product="ATP-binding cassette sub-family C member 12"
                     /note="multidrug resistance-associated protein 9;
                     ATP-binding cassette transporter sub-family C member 12;
                     ATP-binding cassette, sub-family C (CFTR/MRP), member 12;
                     ATP-binding cassette, subfamily C (CFTR/MRP), member 12"
                     /calculated_mol_wt=152835
     Region          43..1366
                     /region_name="MRP_assoc_pro"
                     /note="multi drug resistance-associated protein (MRP);
                     TIGR00957"
                     /db_xref="CDD:188098"
     Site            125..145
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            160..180
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            235..255
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            257..277
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            349..369
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            377..397
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            439
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6Y306.1)"
     Region          472..494
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Region          729..751
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            788..808
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            837
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            850..870
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            943..963
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            978
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q6Y306.1)"
     Site            1038..1058
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6Y306.1)"
     CDS             1..1366
                     /gene="Abcc12"
                     /coded_by="NM_199377.1:72..4172"
                     /db_xref="GeneID:291923"
                     /db_xref="RGD:735100"
ORIGIN      
        1 mvgedpylis dldrrgrrrs faerydpslk tmipmrpyar lapnpvddag llsfatfswl
       61 tpvmirsykh tltvdtlppl spydssdvna krlqilwdee iervgperas lgrvvwkfqr
      121 trvlmdvvan ilciimaalg ptvlihqilq hvtnissghi gisiclclal fateftkvlf
      181 ralawainyr tairlkvals tlifknllsf ktlthisage vlnvlssdsy slfeaalfcp
      241 lpatipilmv vcavyaffil gstalvgicv ylifipiqmf maklnsafrr saisvtdkrv
      301 qtmnefltci klikmyawek sfmntihdir krekklleka gyvqsgnsal apivstiaiv
      361 stftchiflk rtltapvafs viamfnvmkf siailpfsvk avaeasvslr rmkkilvaks
      421 ppsyitqped pdtilllana tltweqeinr krgpsktqdq rrhvfkkqra elyseqslsd
      481 qgvasperqs gspksvlhni sfvvrkgkvl gicgnvgsgk sslisallgq mqlqkgvvaa
      541 sgplayvsqq awifhgnvre nilfgekynh qryqhtvhvc glqkdlnslp ygdlteiger
      601 gvnlsggqrq rislaravya nrqlyllddp lsavdahvgk hvfeecikkt lkgktvvlvt
      661 hqlqflescd evilledgei cekgthkelm eergryakli hnlrglqfkd pehiynvamv
      721 etlkesqaqr dedavlasgd erdegkepet eefvdikapv hqliqiespq egivtwktyh
      781 tyikasggyl vsflvlclff lmmgssafst wwlglwldsg sqvicapqsn etacnvnqtl
      841 qdtkhhmyql vyiasmmsvl tfgiikgftf tnttlmasss lhnrvfnkiv sspmsffdtt
      901 ptgrlmnrfs kdmdeldvrl pfhaenflqq fsmvvfilvi maasfpvvlv vlaglailff
      961 illrifhrgv qelkqvenis rspwfshits smqglgviha ydkkddcisk fkalndenss
     1021 hllyfncalr wfalrmdilm nivtfvvall vtlsfssisa sskglslsyi iqlsgllqvc
     1081 vrtgtetqak ftsaelmrey istcvpehtq sfkvgtcpkd wpsrgeitfk dyrmryrdnt
     1141 plvldglnln iqsgqtvgiv grtgsgkssl gmalfrlvep asgtifidev dictvgleel
     1201 rtkltmipqd pvlfvgtvry nldplgshtd emlwhvlert fmrdtimklp eklqaevten
     1261 genfsvgerq llcmarallr nskiilldea tasmdsktdt lvqstikeaf ksctvltiah
     1321 rlntvlncdl vlvmengkvi efdkpevlae kpdsafamll aaevgl
//
