LOCUS       NM_001108201            4859 bp    mRNA    linear   ROD 12-JUN-2023
DEFINITION  Rattus norvegicus ATP binding cassette subfamily C member 10
            (Abcc10), mRNA.
ACCESSION   NM_001108201 XM_001066454 XM_236930
VERSION     NM_001108201.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H,
            Elsasser HP, Mann M and Hasilik A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   2  (bases 1 to 4859)
  AUTHORS   Hagenbuch B, Gao B and Meier PJ.
  TITLE     Transport of xenobiotics across the blood-brain barrier
  JOURNAL   News Physiol Sci 17, 231-234 (2002)
   PUBMED   12433976
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473987.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236930.4, XM_001066454.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132291,
                              SAMD00132308 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..4859
                     /gene="Abcc10"
                     /note="ATP binding cassette subfamily C member 10"
                     /db_xref="GeneID:316231"
                     /db_xref="RGD:1306696"
     exon            1..232
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..4556
                     /gene="Abcc10"
                     /note="multidrug resistance-associated protein 7;
                     ATP-binding cassette, sub-family C (CFTR/MRP), member 10;
                     ATP-binding cassette, subfamily C (CFTR/MRP), member 10"
                     /codon_start=1
                     /product="ATP-binding cassette sub-family C member 10"
                     /protein_id="NP_001101671.1"
                     /db_xref="GeneID:316231"
                     /db_xref="RGD:1306696"
                     /translation="MEGLLAQLCGTDAARPLPLWEGDTTGHCFTQLVLSVLPHALLAV
                     LSACHLGTPRTNNIIQPFNPGWRLRLTASFLLSVFPLLDLLPVVLPPVSHPGPLWLEV
                     LAGCVTAVAWFTHSLALWALVHSPHGHSRGPLALALAAFLPTPALVLTLLWHCQRGTF
                     LPPLLPGPLGRVCLLILQLAAVLAYGLGWAAPGGPREPWTHDPFLSPESQEREVAEDG
                     ESWLSRFSYAWLAPLLARGVRGELRQPQDTCRLPRRLHPAYLARAFQAHWKEGAQLWR
                     ALYGAFGCCYIALGLLKMVGTMLGFSGPLLLSLLVGFLEEGQEPLSHGLLYVLGLASG
                     SVISAVLQNQYGYEVRKVTLQARVAVLSILYRKTLKLGPSRPPTGEVLNLLGTDSERL
                     LNFAGSFHEAWGLPLQLAITLYLLYEQVGVAFLAGLVLALLLVPVNKVIATRIMANNQ
                     EMLRHKDARVKLMTELLSGIRVLKFFRWEQALGDRVKACRTQELGRLRVIKYLDAACV
                     YLWAALPVVICIVIFITYVLLGHQLTATKVFTALALVHMLILPLNNFPWVINGLLESK
                     VSLDRIQRFLDLPSYSPEAYYSPDPPTEPSTVLELHEALFSWDPTGTSQKTFISHLQV
                     KKGMLVGIVGKVGCGKSSLLAAITGELHRLCGWVAVSDLSKGFGLATQEPWIQCATIR
                     DNVLFGKTFDAQLYREVLEACALNDDLSILPAGDQTEVGEKGVTLSGGQRARIALARA
                     VYQEKTLYLLDDPLAAVDADVANHLLHRCILGVLGHTTRLLCTHRTEYLERADLVLLM
                     EAGRLVRAGPPSEILPLVQAAPTALADKEQVTDSGQSPSVHNLEKTTEELDVAQNTSG
                     RLVQEESKSEGAVALHVYRAYWRAMGSGLATAILISLLLMQATRNGADWWLAHWLSQL
                     KAGRNSSEERPASSSPRSMGFFSPRLLLFSPGNLYIPLHKATSNGSSDVHFYLTVYAT
                     IAGVNSLCTLLRAVLFAAGALQAAASLHHRLLHRLLMAPVTFYDSTPSGRVLNRFSSD
                     VACVDDSLPFLLNILLANSVGLLGLLAVLGSGLPWLLLLLPPLSFIYYGVQRRYRASF
                     RELRRLGSLTLSPLYSHLADTLAGLPVLRAAGATYRFEEENQRLLELNQRCQFASYAT
                     MQWLDIRLQLMGAAVVSAIAGIALVQHQQGLANPGLVGLVLSYALSLTGLLSGLVSSF
                     TQTEAMMVSVERLEEYSCDIPQEPHGQPPQSPHQRVSWLTQGSVEFQDVVLVYRPGLP
                     NALDGVTFRVEPGEKLGIVGRTGSGKSSLFLVLFRLLEPSAGQVLLDGVDTSQLELAE
                     LRSQLAVIPQEPFLFSGTVRENLDPQGLHEDRALWQALEQCHLSEVAMAIGGLDGELG
                     ERGRDLSLGQRQLLCLARALLTDAKILCIDEATASVDQKTDQLLQQTICRRFANKTVL
                     TIAHRLNTILNSDRVLVLQAGRVVELDSPSALRNQPHSLFRQLLQSSQQGAHSLPAAC
                     "
     exon            233..1454
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1682
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1839
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..1949
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            1950..2029
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2030..2201
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2300
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2490
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..2568
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2569..2763
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2764..2917
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            2918..3098
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            3099..3442
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            3443..3612
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            3613..3773
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            3774..4036
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            4037..4182
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4280
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            4281..4393
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
     exon            4394..4859
                     /gene="Abcc10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggggcgggc tttaactggg gactctgtcc cgagccctgt cactctcggc ttccgcctag
       61 gtgagctgtc tatggagggg ctcctggccc agctttgtgg cacggatgcg gcgcggccac
      121 tcccgctctg ggaaggggac accacgggcc actgcttcac ccagctggtg ctcagcgtcc
      181 ttccacacgc tctcctcgcc gtcctcagcg cctgccactt gggcacccca aggactaaca
      241 atatcatcca acctttcaat cctggctggc gcctccgact cacagcttcc ttcctcctct
      301 ccgtcttccc gctgctagac ctccttccgg ttgttttacc tccggtgtca cacccagggc
      361 ccctatggct agaagtgctg gcagggtgtg tgactgctgt ggcctggttc acccacagcc
      421 tggccctgtg ggcattggtt cattcccctc atggccattc tcgtggaccc ttggccttgg
      481 ctctggcagc cttcttgcca accccagccc tggtactgac cctgctgtgg cattgccagc
      541 gaggtacatt tctgcccccg cttctcccag gacctctggg ccgtgtgtgt cttctcatcc
      601 tgcagttggc agccgtcttg gcctatgggc tgggctgggc agcccctggg ggacctcgag
      661 agccctggac tcacgatccc ttcctgtccc ctgagagtca agaaagagag gtagctgaag
      721 acggagagag ttggctgtca cgcttttcct atgcctggtt ggcacctctg cttgctcgtg
      781 gagtccgagg agagctccgg cagccccagg acacttgccg cctcccccgc agactgcacc
      841 ctgcctacct ggcccgagcc ttccaagcgc actggaagga gggggcccaa ctgtggaggg
      901 ccctgtatgg ggcctttgga tgttgctaca tagcccttgg actgttgaag atggtgggga
      961 ccatgctggg cttctctggg cctttactgc tctccctact ggtgggcttc ctggaggaag
     1021 ggcaagagcc tctaagccac ggcctgctct acgtcctggg gctggccagt gggtctgtga
     1081 taagcgccgt actacagaac cagtatgggt atgaggtgcg taaagtgaca cttcaggcac
     1141 gggtggctgt gctgagcatc ctttaccgca aaaccttgaa gcttgggcct agccgccctc
     1201 ccactgggga ggtcctgaac ctactaggca ccgactccga gaggctgctt aactttgctg
     1261 gcagcttcca tgaggcctgg ggcctgcctc tgcaactggc catcactctc tacctgctgt
     1321 acgagcaggt gggcgtggcc ttcctggctg ggttagtctt ggcactgctc ctggtgcctg
     1381 tcaacaaagt gatcgccacc cgaatcatgg ccaacaacca ggagatgctc cggcacaagg
     1441 atgcacgggt taagctcatg acagagctgc tgagcggcat tcgagtcctc aagttcttca
     1501 ggtgggagca ggctctgggg gaccgggtga aggcttgccg gacccaagag ctgggacggc
     1561 tccgcgtcat caaatacctg gatgcagcct gcgtgtacct ctgggctgct ctgcctgtag
     1621 tcatctgcat cgtcatcttc atcacctacg tcctcctggg gcaccagctc actgccacca
     1681 aggtgtttac agcactggca cttgtgcaca tgctcattct tcctctcaac aacttcccct
     1741 gggtgatcaa tggtctcttg gaatccaaag tatccctgga ccggatccag cgtttcctcg
     1801 accttccaag ctatagccct gaggcctact acagtcctga tccccccaca gagccatcca
     1861 cagtactgga gctgcatgaa gccctgttct cctgggaccc aactggaaca agccagaaga
     1921 ccttcatcag tcacctccaa gtgaaaaagg gcatgctggt gggcatcgtg ggaaaggtcg
     1981 gctgtgggaa gagttcactg ctggctgcca tcactgggga gctccacagg ctgtgtgggt
     2041 gggtggcagt gtcagacctg tccaaaggct ttggactggc cactcaggag ccctggatcc
     2101 agtgtgccac catcagagac aacgtcctgt ttgggaagac atttgatgcc cagctgtaca
     2161 gggaggtgct ggaggcctgc gccctcaatg atgatctcag catcctgcct gctggagacc
     2221 agacagaggt tggagagaag ggtgtgaccc tcagcggggg acagagggcc cggattgccc
     2281 ttgcccgagc tgtctaccag gagaaaacac tctacctcct tgatgaccct ctggctgctg
     2341 tggatgcaga tgtggccaac cacctgttgc acaggtgcat cctgggagtg ctgggccaca
     2401 ccacccggct gctgtgcacc catcgcaccg agtacctgga gagggctgac ctggtgctgt
     2461 tgatggaggc tgggcgcctg gtccgagcag ggcctccctc agagattctg ccattggtgc
     2521 aagctgcccc cacagccttg gctgacaagg aacaagtgac tgactcaggt cagtccccgt
     2581 ctgtacacaa cctagagaaa accacagagg agctggacgt ggcgcagaac acatccggtc
     2641 gcctcgtgca ggaggagagc aaaagcgagg gcgccgtggc cctgcacgtg taccgagcat
     2701 actggagggc catgggcagt ggcctggcca ccgccatcct catctccctg ctcctcatgc
     2761 aagccacgcg caacggtgct gattggtggc tcgctcactg gctctctcag ctgaaggcag
     2821 gcagaaatag ctccgaggag cgtcccgctt cctccagccc acgctccatg ggattcttct
     2881 ccccacggct gctcctcttc tcccccggaa acctctacat cccactgcac aaagctactt
     2941 ccaatggctc ctcagacgtc cacttctacc tcaccgtgta cgcaaccatt gctggtgtca
     3001 attccctctg caccctgctc cgggctgtgc tctttgcagc aggtgccctt caagcagctg
     3061 ctagcctaca ccaccgtcta ctgcaccgac tgctcatggc accagtgact ttctatgact
     3121 ccacaccttc cggccgggtc ttgaaccgct tctcctcaga cgtcgcctgt gtagacgaca
     3181 gcctgccctt cctcctcaac atcctgctgg ccaattctgt agggctgctg ggcctcctcg
     3241 ctgtcctggg ttctggtctg ccctggctgc tgctcctgct gccgcctctg agcttcatct
     3301 actacggcgt gcagcgccgc tacagggctt ccttccggga gctgcggcgt ctgggcagcc
     3361 tcaccttgtc tccgctctac tcccacctgg ctgacaccct ggcaggcctc cctgtgctcc
     3421 gggctgcagg ggccacttac aggtttgagg aggagaacca gcgactcttg gagctgaacc
     3481 agaggtgcca gtttgcttcc tatgccacga tgcagtggtt ggacattcgg ctgcagctca
     3541 tgggggcagc ggtggtcagc gccattgcgg gcattgccct ggtgcagcac cagcagggcc
     3601 ttgccaaccc agggctggtg ggcctcgtgc tttcttatgc actgtctctg acgggcctgc
     3661 tctccggcct ggtgagcagc ttcacacaga cggaagccat gatggtgagc gttgaacgac
     3721 tggaggaata ttcctgtgac attccccagg agccccatgg ccagccacca cagtcacccc
     3781 accagcgcgt cagctggctg acccagggaa gtgtggagtt ccaggatgtg gtgctggtgt
     3841 atcggccagg gctgccaaat gccctagacg gggtgacctt tcgcgtggag cctggcgaga
     3901 agctgggcat tgtgggccgc acaggctccg gcaagtcttc cctgtttctg gtgctcttcc
     3961 ggctgctgga gcccagtgca gggcaagtgc tcctggacgg tgtggacacc agccagctgg
     4021 agctggctga gctcagatcc cagctggctg tcatccccca ggagcccttc ttgttcagtg
     4081 ggaccgttcg ggagaacctg gacccccagg gcctacatga ggacagggcc ctgtggcaag
     4141 ccctagaaca gtgccacctg agtgaggtgg ccatggccat aggaggcctg gatggggagc
     4201 tgggcgaaag gggcagggac ttgtccctag ggcagagaca gctgctatgc ctggcaaggg
     4261 ctcttctcac agatgctaag atcttgtgca ttgacgaggc cacggcaagt gtggaccaga
     4321 agacagacca gctgctccag caaaccatct gcagacgctt tgccaacaag acagtgctga
     4381 ccattgccca caggctcaac acgatcctaa actctgaccg ggtgctggtg ctccaagccg
     4441 ggagggtggt ggaactggac tccccctcag ccctgcgcaa ccagccccat tccctgttta
     4501 ggcagctcct gcagagcagc cagcaggggg cccactccct tcctgccgcg tgctgagcct
     4561 ccctcccact ggggcgtgtg ctccttccca ccaggcctgc tggttacatc ctcctctgtg
     4621 ctcctacctc tcccccactc cctcagaggg gacacagcac cctggcttcc tccatgaaaa
     4681 ccactcctag tgggggccga agactgaggc ttccccagaa ccagcccacg tgggcccttt
     4741 tacccagaat tctgggccgg ttttccttcc gtagaagccc acttgcattt tcataatttt
     4801 atttgataaa attcctatct tacattctgt gttttaaaaa aataatattt ctgatgtga
//
