LOCUS       NM_022238               3320 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus ATP binding cassette subfamily B member 9
            (Abcb9), mRNA.
ACCESSION   NM_022238
VERSION     NM_022238.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3320)
  AUTHORS   Demirel,O., Jan,I., Wolters,D., Blanz,J., Saftig,P., Tampe,R. and
            Abele,R.
  TITLE     The lysosomal polypeptide transporter TAPL is stabilized by
            interaction with LAMP-1 and LAMP-2
  JOURNAL   J Cell Sci 125 (Pt 18), 4230-4240 (2012)
   PUBMED   22641697
REFERENCE   2  (bases 1 to 3320)
  AUTHORS   Kamakura,A., Fujimoto,Y., Motohashi,Y., Ohashi,K.,
            Ohashi-Kobayashi,A. and Maeda,M.
  TITLE     Functional dissection of transmembrane domains of human TAP-like
            (ABCB9)
  JOURNAL   Biochem Biophys Res Commun 377 (3), 847-851 (2008)
   PUBMED   18952056
REFERENCE   3  (bases 1 to 3320)
  AUTHORS   Zhao,C., Haase,W., Tampe,R. and Abele,R.
  TITLE     Peptide specificity and lipid activation of the lysosomal transport
            complex ABCB9 (TAPL)
  JOURNAL   J Biol Chem 283 (25), 17083-17091 (2008)
   PUBMED   18434309
REFERENCE   4  (bases 1 to 3320)
  AUTHORS   Demirel,O., Waibler,Z., Kalinke,U., Grunebach,F., Appel,S.,
            Brossart,P., Hasilik,A., Tampe,R. and Abele,R.
  TITLE     Identification of a lysosomal peptide transport system induced
            during dendritic cell development
  JOURNAL   J Biol Chem 282 (52), 37836-37843 (2007)
   PUBMED   17977821
REFERENCE   5  (bases 1 to 3320)
  AUTHORS   Schroder,B., Wrocklage,C., Pan,C., Jager,R., Kosters,B.,
            Schafer,H., Elsasser,H.P., Mann,M. and Hasilik,A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   6  (bases 1 to 3320)
  AUTHORS   Kobayashi,A., Maeda,T. and Maeda,M.
  TITLE     Membrane localization of transporter associated with antigen
            processing (TAP)-like (ABCB9) visualized in vivo with a
            fluorescence protein-fusion technique
  JOURNAL   Biol Pharm Bull 27 (12), 1916-1922 (2004)
   PUBMED   15577206
REFERENCE   7  (bases 1 to 3320)
  AUTHORS   Yamaguchi,Y., Iseoka,H., Kobayashi,A. and Maeda,M.
  TITLE     The carboxyl terminal sequence of rat transporter associated with
            antigen processing (TAP)-like (ABCB9) is heterogeneous due to
            splicing of its mRNA
  JOURNAL   Biol Pharm Bull 27 (1), 100-104 (2004)
   PUBMED   14709908
REFERENCE   8  (bases 1 to 3320)
  AUTHORS   Kobayashi,A., Kasano,M., Maeda,T., Hori,S., Motojima,K., Suzuki,M.,
            Fujiwara,T., Takahashi,E., Yabe,T., Tanaka,K., Kasahara,M.,
            Yamaguchi,Y. and Maeda,M.
  TITLE     A half-type ABC transporter TAPL is highly conserved between rodent
            and man, and the human gene is not responsive to interferon-gamma
            in contrast to TAP1 and TAP2
  JOURNAL   J Biochem 128 (4), 711-718 (2000)
   PUBMED   11011155
REFERENCE   9  (bases 1 to 3320)
  AUTHORS   Zhang,F., Zhang,W., Liu,L., Fisher,C.L., Hui,D., Childs,S.,
            Dorovini-Zis,K. and Ling,V.
  TITLE     Characterization of ABCB9, an ATP binding cassette protein
            associated with lysosomes
  JOURNAL   J Biol Chem 275 (30), 23287-23294 (2000)
   PUBMED   10748049
REFERENCE   10 (bases 1 to 3320)
  AUTHORS   Yamaguchi,Y., Kasano,M., Terada,T., Sato,R. and Maeda,M.
  TITLE     An ABC transporter homologous to TAP proteins
  JOURNAL   FEBS Lett 457 (2), 231-236 (1999)
   PUBMED   10471785
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000228.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by NM_022238.3.
            
            On Mar 5, 2021 this sequence version replaced NM_022238.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB027520.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               JACYVU010000228.1  1704626-1704772
            148-822             JACYVU010000228.1  1710198-1710872
            823-937             JACYVU010000228.1  1716477-1716591
            938-1068            JACYVU010000228.1  1716972-1717102
            1069-1274           JACYVU010000228.1  1718029-1718234
            1275-1472           JACYVU010000228.1  1719894-1720091
            1473-1601           JACYVU010000228.1  1721151-1721279
            1602-1790           JACYVU010000228.1  1722733-1722921
            1791-1964           JACYVU010000228.1  1723587-1723760
            1965-2124           JACYVU010000228.1  1726174-1726333
            2125-2261           JACYVU010000228.1  1727789-1727925
            2262-3320           JACYVU010000228.1  1736287-1737345
FEATURES             Location/Qualifiers
     source          1..3320
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q15"
     gene            1..3320
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /note="ATP binding cassette subfamily B member 9"
                     /db_xref="GeneID:63886"
                     /db_xref="RGD:620254"
     exon            1..147
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            148..822
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..2522
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /EC_number="7.4.2.6"
                     /note="ATP-binding cassette sub-family B member 9;
                     TAP-like protein; ABC transporter 9 protein; ATP-binding
                     cassette transporter 9; ATP-binding cassette, sub-family B
                     (MDR/TAP), member 9; TAP-like ABC transporter; ATP-binding
                     cassette, subfamily B (MDR/TAP), member 9"
                     /codon_start=1
                     /product="ABC-type oligopeptide transporter ABCB9"
                     /protein_id="NP_071574.1"
                     /db_xref="GeneID:63886"
                     /db_xref="RGD:620254"
                     /translation="MRLWKAVVVTLAFVSMDVGVTTAIYAFSHLDRSLLEDIRHFNIF
                     DSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMAKLL
                     LFSEVRRPIRDPWFWALFVWTYISLAASFLLWGLLATVRPDAEALEPGNEGFHGEGGA
                     PAEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDSIVIQKSM
                     DQFTTAVVVVCLLAIGSSLAAGIRGGIFTLVFARLNIRLRNCLFRSLVSQETSFFDEN
                     RTGDLISRLTSDTTMVSDLVSQNINIFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPI
                     IMMVSNIYGKYYKRLSKEVQSALARASTTAEETISAMKTVRSFANEEEEAEVFLRKLQ
                     QVYKLNRKEAAAYMSYVWGSGLTLLVVQVSILYYGGHLVISGQMSSGNLIAFIIYEFV
                     LGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGRLAPDHLEGRVDFENVTFT
                     YRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLQGGRVLLDGEPI
                     GAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMEL
                     QDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIH
                     GNLQRHTVLIIAHRLSTVERAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLG
                     LEHPLDYTAGHKEPPSNTEHKA"
     exon            823..937
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1068
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1274
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1472
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1601
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1602..1790
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1964
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2124
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2261
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
     exon            2262..3320
                     /gene="Abcb9"
                     /gene_synonym="Tapl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggctccgac cttgtagcgg cgcagcgccg gctccgaggc agagcggctg ctcagcgcgg
       61 ggcctcagtg agaggcagga tcctgtgtct ctgcgtcccg ggcacggcgc gtcacttctg
      121 gacgactcac ctggtggcag gtggcaggtg tggccttacc cggctgtcag tgatggcctt
      181 gccccggtga gccaaagcct gcccctgtca cccgccggcc gccagccagc aggatgaggc
      241 tgtggaaggc ggtagtggtg acgctggcct tcgtgagcat ggacgtcggc gtgaccacgg
      301 ccatctatgc cttcagccac ctggatcgca gcctgctgga ggacatccga cactttaaca
      361 tcttcgactc ggtgctggac ctctgggctg cctgcctgta ccgcagctgc ttgctgctgg
      421 gggctaccat cggtgtggcc aagaacagcg ctctggggcc acggcgcctg cgggcctcgt
      481 ggctcgtcat caccctcgtg tgcctctttg tgggcatcta tgccatggcc aaactgctac
      541 tcttctcaga ggtgcgcagg cccatccggg acccatggtt ctgggcgctc ttcgtatgga
      601 cctacatctc gctggctgcc tccttcctgc tgtgggggct gctggccacc gtgcggccgg
      661 acgcggaggc cctggagccg gggaacgagg gcttccacgg tgagggtggg gcccctgctg
      721 agcaggcatc aggggccacg ctgcagaagc tgctgtccta cacaaagcct gatgtggcct
      781 tcctagtagc tgcctctttc ttcctcatcg tagcggctct gggagagacc ttcctgccct
      841 actacactgg ccgggccatc gacagcatcg tcatccagaa aagcatggac cagttcacca
      901 cggccgtcgt cgtcgtctgc ctgctggcca tcggcagctc attggccgca ggtattcggg
      961 gcggcatttt caccctcgta tttgccagac tgaacattcg ccttcgcaac tgtctcttcc
     1021 gctccctggt gtcacaggag acgagcttct ttgacgagaa tcgcacaggg gacctcatct
     1081 cccgcctcac ctctgacacc accatggtca gcgacctggt ctcccagaac atcaacatct
     1141 tcctgaggaa cacggtcaag gtcacgggcg tggtggtctt catgttcagc ctctcctggc
     1201 agctctccct ggtcaccttc atgggcttcc ccatcatcat gatggtgtcc aacatctacg
     1261 gcaagtacta caagaggctc tccaaggagg tccagagtgc cctggccaga gccagcacca
     1321 cagccgagga gaccatcagc gccatgaaga cggtccgcag ctttgccaat gaggaagagg
     1381 aggcagaggt gttcctgcgg aagcttcagc aggtctacaa gctgaacagg aaggaggccg
     1441 cagcctacat gtcctacgtc tggggcagtg ggctcacact cctggtggtc caggtcagta
     1501 tcctctacta cgggggccac ctcgtcatct cggggcagat gagcagcggc aacctcatcg
     1561 ccttcatcat ctatgagttt gtcctgggag actgcatgga gtccgtgggc tccgtctata
     1621 gcggcctgat gcagggagtg ggggctgctg agaaggtgtt cgagttcatt gaccggcagc
     1681 caaccatggt gcatgacgga agattggccc ctgaccatct cgagggcagg gtggactttg
     1741 agaatgtaac cttcacctac cgcactcggc cccacacaca ggtcctacag aatgtctcct
     1801 tcagcctgtc cccaggcaag gtgacggctc tggtggggcc ctcgggcagc ggaaagagct
     1861 cctgtgtgaa catcctggag aacttctacc ctctgcaggg cggccgggtg ttgttggacg
     1921 gcgagcccat cggcgcctat gaccacaagt acctgcaccg cgtgatctca ctggtaagcc
     1981 aggagcccgt gctgttcgcc cgctccatca cagacaacat ctcctacggc ctgcctaccg
     2041 tgcccttcga gatggtggtg gaggctgcac agaaggccaa tgctcacggc ttcatcatgg
     2101 agctgcagga cggatacagc acagagaccg gggaaaaggg agcccagctg tcaggtggcc
     2161 agaagcagcg ggtggccatg gcacgtgcac tagtgcggaa ccctcctgtg ctcatcctgg
     2221 acgaagccac cagtgccctg gacgcagaga gtgaatacct gattcagcag gccatccacg
     2281 gcaacctgca gagacacacg gtgctgatca tcgcacaccg gctgagtact gtagagcggg
     2341 cgcacctcat cgtggtgcta gacaagggcc gtgtggtaca gcagggtaca caccagcagc
     2401 tgttggcaca gggcggcctc tatgccaagc tggtgcagcg tcagatgctg gggctcgagc
     2461 accccttgga ctacacggct ggccacaagg agccacccag caacactgaa cacaaggcct
     2521 gacagtggcc ccgggctgaa gcgctggagg cgacctgccg agtcccactc ttgcttcctg
     2581 catcttgcct ccttccactt gctccccagg cacccaccag ctgccatggg cttaccccct
     2641 tctactgtgt cccatcttgg ctcctccagg cctgccaagg tagaacagcc tttttaaacc
     2701 aagctagcag ggtttttact gctcagttca acgcactcca gtcaactcct agatttcaaa
     2761 aacacctttt tgggaccggc agtgagcaag ctcactagga tgttttcaag acttctgagc
     2821 caggagtgca cgaccctttc taactgcctg gaagatgtct gggagagaac taagcactac
     2881 cctttgcctc tgggagaagc agcttccctg tcccctaggg ggacacaagg gttggccttc
     2941 catccttcca gtctcccggc tctgtgagtc aggccagagg tggggcaaga gagtgggagg
     3001 tgcccactgc ctatcacccc ttgccaatca aagccagtct cactgtgaac caccagaacc
     3061 tcagcagagg aggggctggc caggcctggt gggcctcggg gtgccctcag ccccacaccc
     3121 agcacttgaa cccttcatcc tttcccctgg ctggcacctt cccctcctgt ccacccctgc
     3181 aactctgcag aggaaccttg tttgtaagat gtattctcag attggtggag gggaccgagg
     3241 caatgcccag ggtctggctt tgtcctggtt taagattttg ggagaactgg gtcaataaag
     3301 tgtactacct ctgacctcta
//
