LOCUS       XM_039105932            5205 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ATP binding cassette subfamily B
            member 11 (Abcb11), transcript variant X2, mRNA.
ACCESSION   XM_039105932
VERSION     XM_039105932.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039105932.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5205
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5205
                     /gene="Abcb11"
                     /gene_synonym="Bsep; Spgp"
                     /note="ATP binding cassette subfamily B member 11; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 16 ESTs, 7 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     4 samples with support for all annotated introns"
                     /db_xref="GeneID:83569"
                     /db_xref="RGD:619930"
     CDS             158..4123
                     /gene="Abcb11"
                     /gene_synonym="Bsep; Spgp"
                     /codon_start=1
                     /product="bile salt export pump isoform X1"
                     /protein_id="XP_038961860.1"
                     /db_xref="GeneID:83569"
                     /db_xref="RGD:619930"
                     /translation="MSDSVILRSVKKFGEENHAFESDGSHNNDKKSRLQDKMKEGDIR
                     VGFFELFRFSSSKDIWLMLMGGVCALLHGMAQPGILIIFGIMTDIFIKYDIERQELEI
                     PGKACVNNTIVWINSSFHQNMTNGTVCGLVDIESEMIKFSGIYAGVGMTVLILGYFQI
                     RLWVITGARQIRRMRKIYFRRIMRMEIGWFDCTSVGELNSRFADDIEKINDAIADQLA
                     HFLQRMSTAMCGLLLGFYRGWKLTLVILAVSPLIGIGAAVIGLSIAKFTELELKAYAK
                     AGSIADEVLSSIRTVAAFGGENKEVERYEKNLVFAQRWGIWKGMVMGFFTGYMWCLIF
                     FCYALAFWYGSTLVLDEEEYTPGTLVQIFLCVILAAMNIGHASSCLEIFSTGCSAATN
                     IFQTIDRQPVIDCMSGDGYKLDRIKGEIEFHNVTFHYPSRPDVKILDNLSMVIKPGET
                     TALVGSSGAGKSTALQLIQRFYDPCEGMVTLDGHDIRSLNIRWLRDQIGIVEQEPVLF
                     STTIAENIRFGREDATMEDIVQAAKDANAYNFIMALPQQFDTLVGEGGGQMSGGQKQR
                     VAIARALIRNPKILLLDMATSALDNESEARVQEALNKIQHGHTIISVAHRLSTVRAAD
                     VIIGFEHGVAVERGTHEELLERKGVYFMLVTLQSQGDNAHKETSIMGKDATEGGTLER
                     TFSRGSYRDSLRASIRQRSKSQLSLLTHDPPLAVADHKSSYKDSKDNDVLVEEVEPAP
                     VRRILKYNIPEWHYILVGSLSAAINGAVTPIYSLLFSQLLGTFSLLDKEQQRSEIHSM
                     CLFFVILGCVSIFTQFLQGYTFAKSGELLTKRLRKFGFKAMLGQDIGWFDDLRNNPGV
                     LTTRLATDASQVQGATGSQVGMMVNSFTNIIAALLIAFFFSWKLSLIITIFFPFLALS
                     GAVQTKMLTGFASQDKQALEKAGQITSEALSNIRTVAGIGVEGRFIKAFEVELQTSYK
                     TAVRKANIYGLCFAFSQGIAFLANSAAYRYGGYLIAYEGLGFSHVFRVVSSVALSATA
                     VGRTFSYTPSYAKAKISAARFFQLLDRKPPINVYSEAGEKWDNFQGKIDFIDCKFTYP
                     SRPDIQVLNGLSVSVNPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGTVMIDGHDSKK
                     VNIQFLRSNIGIVSQEPVLFDCSIMDNIKYGDNTKEISVERAIAAAKQAQLHDFVMSL
                     PEKYETNVGIQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQTALD
                     KAREGRTCIVIAHRLSTIQNSDIIAVVSQGVVIEKGTHEKLMAQKGAYYKLVITGAPI
                     S"
ORIGIN      
        1 tgttctggaa aaagcctgat ttctgttcgg tgctttatta cgatgaaaac tgaacttgaa
       61 aactggtgta caatcctgac tttccacagt ggggtctctc tcttctcctg gctccgtcaa
      121 gttcacatct gtagggttgt tgagtgcaga ttctgcaatg tctgactcag tgattcttcg
      181 cagcgtgaag aaatttggag aggagaatca tgctttcgaa tcagatggat cacataacaa
      241 tgataagaaa tcaaggttac aagataagat gaaggaggga gacattcgag ttggcttctt
      301 tgaactgttt cgattttctt catcaaaaga catctggctg atgcttatgg gaggcgtatg
      361 cgcattgcta catggaatgg cccagccagg catacttatt atttttggta taatgacaga
      421 tatttttatt aaatatgaca ttgaaaggca agaactcgag ataccaggaa aagcgtgtgt
      481 gaataacacc attgtatgga tcaacagctc cttccaccag aacatgacaa atggaacagt
      541 ctgtgggttg gtggacattg aaagtgaaat gatcaaattc tctggcatct acgcaggagt
      601 cggcatgacc gtacttatcc ttggatactt tcaaataagg ttatgggtca tcactggggc
      661 tcgtcagata aggagaatga ggaaaattta cttccggaga ataatgagaa tggaaattgg
      721 gtggttcgac tgcacttctg tgggagagct gaattcaagg tttgctgatg atattgaaaa
      781 aatcaatgac gccattgccg accagttggc tcatttcctc cagcgcatgt cgacggctat
      841 gtgtgggtta cttttagggt tctacagggg ttggaaacta accttggtga ttcttgctgt
      901 cagccctctc attggcattg gggcagccgt cataggtctg agtatagcca agttcacgga
      961 gcttgagttg aaggcttatg ccaaagcggg gtctattgct gatgaagtcc tctcatctat
     1021 tcgaacagtg gccgcttttg gtggtgagaa caaagaggtt gaaaggtatg agaaaaatct
     1081 tgtgtttgcc cagcgctggg gaatttggaa aggaatggtg atgggcttct tcactgggta
     1141 catgtggtgt ctcattttct tctgttatgc actggccttc tggtatggtt ccacacttgt
     1201 cctagatgaa gaagagtata caccagggac actggtccag attttcctct gtgtcatatt
     1261 agcagctatg aatattggcc atgcatcttc ttgcttggaa atcttctcca ctgggtgttc
     1321 agcagctacc aatatttttc aaacaataga caggcaacct gtcattgact gcatgtcagg
     1381 agacggctac aagctagacc gaatcaaggg tgaaattgag ttccacaatg tgaccttcca
     1441 ttatccttct agaccggacg tgaagatttt agataacctc agcatggtca taaagccagg
     1501 ggaaacgacg gctctggtgg gatccagtgg ggctgggaag agtacagcat tacagctcat
     1561 tcagagattc tatgacccct gtgaaggcat ggtgactctg gacggccatg acattcgctc
     1621 tcttaacatc cggtggctga gagatcaaat cgggatcgtg gaacaggagc ccgttctgtt
     1681 ctccaccact atcgcagaaa acatccgttt tggcagagaa gatgcaacaa tggaagacat
     1741 agtccaagct gccaaggatg ctaatgcata caacttcatt atggccctgc cgcagcaatt
     1801 tgacaccctt gttggagaag gaggaggcca gatgagtggt ggtcagaagc aaagagtagc
     1861 cattgcccga gccctcatac ggaatcccaa gatcttgctt ctggatatgg ctacctcagc
     1921 actggacaat gagagtgaag ctagagtaca agaagcattg aataagatcc aacatgggca
     1981 tacaatcatc tcagttgccc atcgcctgtc aacagtcaga gctgcagatg tgatcattgg
     2041 gtttgagcat ggagtagctg tggaaagagg cacccatgaa gagctgctag aaagaaaagg
     2101 tgtctacttc atgcttgtga ccctgcaaag ccaaggagat aatgctcaca aagaaacgag
     2161 cataatgggg aaagatgcga cggaaggtgg cacccttgag aggacctttt ccagaggcag
     2221 ctatcgggat agtttaagag cttcgatccg gcaacgctcc aagtctcagc tgtctcttct
     2281 gacacatgac cctccactgg ctgttgctga tcacaaatcc tcttacaaag acagcaagga
     2341 caatgacgtg cttgtggaag aagttgaacc tgccccagtt aggaggattc taaaatacaa
     2401 cattccagaa tggcactaca ttctggtagg atctttgagt gcagccatta atggggcagt
     2461 cacacccatc tactcccttt tattcagcca gctccttggg actttttcac tcctcgataa
     2521 agaacaacaa aggtcagaga ttcacagcat gtgtctgttc tttgtcatcc tgggctgtgt
     2581 atccattttc acacaatttc tgcagggtta cacttttgcc aaatccggag agctcctcac
     2641 aaagaggctg cggaaatttg gtttcaaggc aatgttagga caagatatcg gctggttcga
     2701 tgacctcaga aataatcctg gagtactgac gactaggctt gctacagatg cttcccaagt
     2761 tcaaggggct actggctctc aagttggaat gatggtcaat tccttcacta acatcattgc
     2821 ggccttgctg attgccttct tctttagctg gaagctcagt ctgattataa cgatcttctt
     2881 cccctttctg gctttatcgg gagctgtaca gacaaaaatg ttgacgggat tcgcttctca
     2941 agacaagcaa gctctggaga aggctggtca gatcaccagt gaagccctca gcaatatccg
     3001 cacagttgct gggattggag tggagggaag atttattaaa gcatttgagg ttgagctcca
     3061 gacatcatac aagactgctg tcaggaaggc gaatatctat ggactctgct ttgccttttc
     3121 ccaggggata gcatttcttg caaattccgc tgcctataga tatggaggtt acttaatagc
     3181 ctacgaaggt ctgggcttca gccacgtttt cagggtggtc tcttcagttg cactgagtgc
     3241 aacagccgtt ggaagaacat tctcttatac tccgagctat gccaaagcta aaatatcagc
     3301 tgcacgcttt tttcaactgc tagatcggaa acctccaatt aatgtgtaca gtgaagcagg
     3361 tgaaaaatgg gacaacttcc aagggaagat tgattttatt gactgtaaat ttacgtatcc
     3421 ttctcgaccc gatattcaag ttctgaatgg tctctcagta tctgttaatc ctgggcagac
     3481 gctggcattt gttgggagca gtgggtgtgg caaaagcacc agcattcagc tgttggaacg
     3541 gttctatgat cccgatcagg gaactgtgat gatagatggt catgacagca aaaaagtcaa
     3601 cattcagttc ctccgttcca acatcgggat tgtctcccag gagccagtgc tgtttgactg
     3661 tagcataatg gacaacatca agtacgggga caacactaaa gagatctccg tggagagagc
     3721 catagctgct gcaaagcagg ctcagctgca tgacttcgtc atgtcgctcc cagagaaata
     3781 tgaaactaat gttgggatcc agggctctca gctctctcgt ggggagaaac aacgcattgc
     3841 tattgctcgg gccattgtgc gagatcctaa aatcttacta ctggatgaag ctacgtctgc
     3901 cctagacaca gaaagtgaaa agacagtgca gactgctctg gacaaagcca gagagggtcg
     3961 gacctgcatt gtcattgctc atcgtttgtc caccatccag aactcagata tcattgctgt
     4021 cgtgtcacaa ggagtggtga ttgaaaaagg gacccatgag aaactgatgg cccagaaggg
     4081 agcctactac aagctggtca tcactggagc ccccatcagt tgacctgact ggagacttca
     4141 cacagataat gatgtgctga gtacaggagg gctgtgggtt tttgtagcca tatagagaat
     4201 tattaatgct ttacagacag aagtatccac tgggatccaa agtaattttg agtgactttc
     4261 agtaataatt tcagtttgaa atgtctatgt agaaaggaga gagcccagag tcagcatgag
     4321 tcaaagttca aagtccaagg tcaagtagct gcttatctgc cggccagtgc tgctctgggt
     4381 agaaactggt cactgtctcc atcgaggacg ccgcggtgag agcaaggagt cctccttcag
     4441 gacagagggt tatctcttgc atctgggaaa gctccctgcg cactgagcct gctctgtaat
     4501 ctgcactcaa ctgtttgagc cagttcaagg ccaagagcta aggacccaag gctactggta
     4561 tttcttaact aagtttagtt tgtttactat aaggaagcaa atttatttac ctttaactcc
     4621 tgtgagtagg gtggggagcc ctttcccatt ctggcatctc ccaggctcag ggaggccaag
     4681 gtgacaaaag gagaagtaga ggtcgctggt caggtgtgtt gattgtaccg aaggctcagg
     4741 gtattggtgt cactgtacac tacagtggat ctgccagtgt gaagcagggg ctctctacca
     4801 ggacttcgac ttttcattcc ctgccaccat gtcacctgat gtcccttact cttaggaaat
     4861 tctatgcatg gaatggaaat gcatccgaat cttaagttgt tacataaaaa aatctagtaa
     4921 aacatagtag gaaaaaaatg tatgtttgtc attttcttca gaagaccacc aagtactgaa
     4981 ggctcggtgt ttggtgttac aattcactac agtatacagc agtatgtgac gagagacatc
     5041 cgatgctaag gagatagcaa ggaaaatttc ccagccacac accatcctac catgaagctc
     5101 aacatgtacc cactcagtct ctctatgaaa gtgaatatac acacacatga acacatgcac
     5161 acactcacat acacacacat atacatactc acacacacat acaca
//
