LOCUS       XM_006244513            3958 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus alanyl-tRNA synthetase 2,
            mitochondrial (Aars2), transcript variant X1, mRNA.
ACCESSION   XM_006244513
VERSION     XM_006244513.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051344.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006244513.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006244513.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3958
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3958
                     /gene="Aars2"
                     /gene_synonym="Aarsl; AlaRS"
                     /note="alanyl-tRNA synthetase 2, mitochondrial; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 6 ESTs, 1 long SRA read, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 151 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:301254"
                     /db_xref="RGD:1310617"
     CDS             25..3198
                     /gene="Aars2"
                     /gene_synonym="Aarsl; AlaRS"
                     /codon_start=1
                     /product="alanine--tRNA ligase, mitochondrial isoform X1"
                     /protein_id="XP_006244575.1"
                     /db_xref="GeneID:301254"
                     /db_xref="RGD:1310617"
                     /translation="MAASVAAAAGRLRRAIGRSCPWQRFSTEPHPPHGAAVRDAFLSF
                     FRDRHGHRLVPSASVRPRGDPSLLFVNAGMNQFKPIFLGTVDPRSEMAGFRRVANSQK
                     CVRAGGRHNDLEDVGRDLSHHTFFEMLGNWAFGGEYFKKEACSMAWELLTQVYGIPED
                     RLWVSYFSGDSKTGLDPDLETRDIWLSLGVPASRVLSFGLQENFWEMGDTGPCGPCTE
                     IHYDLAGGMGPPQLVELWNLVFMQHYREADGSLHLLPQQHVDTGMGLERLVAVLQGKH
                     STYDTDLFSPLLDAIHQSCRVPPYSGRVGAADEGRIDTAYRVVADHIRTLSVCIADGV
                     SPGMSGAPLVLRRILRRAVRYSTEVLQAPPGFLGNLVPVVVATLGAAYPELQKNSVKI
                     ANLVSEDEAAFLASLQRGRRIIDRTVKRLGPSDLFPAEVAWSLSLSGNLGIPLDLVQL
                     MLEEKGVKLDTAGLEQLAQKEAQHRAQQAEAAQEEGLCLDVHALEELHRQGIPTTDDS
                     PKYNYSLRPNGDYEFGLCEAQVLQLYSETGTAVASVGEGQRCGLLLDRTNFYAEQGGQ
                     ASDRGYLIRTGQQDVLFPVARAQVCGGFILHEAMAPECLQVGDRVQLYVDKAWRMGCM
                     VKHTATHLLNWALRQTLGPTTEQRGSHLNPERLRFDVATQTPLTTEQLRTVESYVQEA
                     VGQDKPVYMEEVPLAHTARIPGLRSLDEVYPDPVRVVSVGVPVAQALAPASQAALQTS
                     VELCCGTHLLSTGAVGDLVIIGDRQLVKGITRLLAITGEQAQQAREVGQSLSQEVEVA
                     SERLSRGSRDLLEAHRLSKDIGRLIEFTESAVIPQWQRQEQQTTLKMLQRRANTAIRK
                     LEKSQQPRGPCDRIEEPRQSQKATDATQESSRTRQSPAHHLSSELMAFMERASMGGRG
                     LSGWVSVQKWNIQLRPLCCSSAPQATEKSQELLKRHSEGPLIVDTVSAQSLSVLVKVV
                     RQLCKQAPSMSVLLLSPQPTGSVLCACQVAQGATPTFTAEAWALAVCSHMGGKAWGSP
                     VIAQGTGHTADLEAALRTARAYALNQL"
ORIGIN      
        1 gcgaagccgt tgcccggagc taaaatggcg gcgtcagtgg ctgctgcggc cgggaggctg
       61 cggcgagcca ttgggaggtc gtgcccatgg cagcggttct caaccgagcc ccacccaccc
      121 cacggagcgg ccgtgcggga cgccttcctg agcttcttcc gagatcgcca cggccaccgg
      181 ctcgtgccct ccgcttccgt gaggccgcgc ggcgacccca gcctgctttt cgtcaacgca
      241 ggcatgaacc agttcaagcc catcttcctg ggcacggtgg atccacgaag cgagatggca
      301 ggcttccgac gagtagctaa cagccagaaa tgtgtcaggg ctggaggacg ccataacgac
      361 ctggaagatg tgggccgtga tctctctcat catacttttt ttgagatgct tggcaactgg
      421 gcttttgggg gtgaatattt taagaaagaa gcatgtagca tggcctggga actgctgact
      481 caagtctatg ggatccctga ggacaggtta tgggtctcct atttcagtgg tgactccaag
      541 acagggttgg acccagacct ggagaccaga gacatctggc tcagcttggg ggtacctgcc
      601 agccgtgtgc tctcgttcgg actgcaagag aacttctggg agatgggaga caccggacct
      661 tgtgggcctt gtaccgagat ccattacgat ctggctggtg gaatgggacc cccccagctg
      721 gttgagctat ggaatctggt cttcatgcaa cactacagag aggcagacgg aagcctgcat
      781 ctgctgccac agcaacatgt ggacacagga atgggcctgg aaagactggt ggctgtactg
      841 cagggcaagc attccaccta cgacaccgac ctcttttctc cactgcttga tgctatacac
      901 cagagctgca gggttccccc gtactctggc cgcgtagggg cagcggatga gggacgaata
      961 gacacagcgt accgagttgt agctgatcac atccgcacgc tcagtgtctg cattgctgat
     1021 ggcgtctccc cggggatgtc aggcgccccg ctagttcttc gtcggattct ccgtcgagct
     1081 gtgcgctatt ccacagaggt cttgcaggca ccacctggct ttctgggcaa cctggtacca
     1141 gtggtggtgg cgacattggg agctgcttac ccagaacttc agaagaactc agtcaagata
     1201 gccaacctgg tgtcagagga tgaggcagcc ttcctggcct ccctgcagag aggccgtcgg
     1261 atcattgatc gcaccgttaa gcgcttgggc ccttctgatt tgttccctgc cgaagtggcc
     1321 tggtcactgt cactgtctgg gaatctgggg atccccctgg acctggtgca gctaatgttg
     1381 gaggagaagg gggtgaagct ggacactgcg ggcctggagc agctagccca gaaggaagcc
     1441 cagcaccggg cccagcaggc agaggcagct caggaggagg gattgtgtct tgatgtccac
     1501 gcactggagg agctgcaccg tcaaggcata cccacaactg atgacagccc caaatataac
     1561 tactctcttc gccccaatgg ggattatgag tttggcctct gtgaggccca ggtattacag
     1621 ctgtattcag agactgggac agctgtggcc tccgtgggag aaggccagcg ctgtggcctc
     1681 ctattggaca gaaccaactt ctatgctgaa caagggggtc aggcttcgga ccgaggctac
     1741 ctcattcgta cagggcagca ggatgtgttg ttccctgtgg cccgggctca ggtctgtgga
     1801 ggcttcatcc tgcatgaggc catggctccc gagtgcttac aagtcgggga ccgagtgcag
     1861 ctctatgtgg ataaggcctg gcgaatggga tgcatggtga agcacacagc cacccacctg
     1921 ctgaactggg cacttcggca gacgctcgga ccaaccaccg aacagcgggg ctcccatctc
     1981 aacccggagc ggctgcgctt tgatgtggcc acgcagaccc cactgaccac agagcagcta
     2041 cggacagtag agagctacgt gcaggaagct gtggggcagg ataagcctgt atacatggag
     2101 gaagtgcccc tggcacacac tgcccgtatc cccggccttc gctcactgga tgaggtgtac
     2161 ccagaccccg ttcgggtcgt gtcagtgggg gttcctgtgg cccaggcact ggcaccagcc
     2221 tcccaagctg cactgcagac ttcggtggag ctgtgctgcg ggacgcacct gctaagtact
     2281 ggggctgtgg gagacctggt gattattggg gatcgccagc tggtcaaagg catcactcgc
     2341 ctactggcca tcaccgggga gcaggcccaa caggcccgag aggtgggcca gagcctgtcg
     2401 caggaggtgg aagtggcaag cgaacggcta agtcggggca gccgggacct gctggaggct
     2461 caccggctat ctaaggacat aggacgtctc attgagttca cagagtctgc tgtgatacct
     2521 cagtggcagc ggcaggagca gcagaccaca ctgaagatgc tacagcgccg tgccaacacc
     2581 gccatccgga aactggagaa gagccagcaa cctagagggc cctgtgacag aatagaagag
     2641 ccaaggcagt cacagaaggc cacagatgca acccaagaaa gcagccgcac caggcagagc
     2701 cccgcccacc acctctcctc agaactgatg gcctttatgg agagagcgag catgggaggg
     2761 cgggggctgt caggctgggt ctcagttcag aagtggaata tccaactccg gcccctctgc
     2821 tgctcctcgg ccccacaggc tacggagaaa tcccaggagc tgttgaaacg gcactcggag
     2881 gggcctctga ttgtggacac tgtctccgcc cagtccctct cggtgctggt aaaggtcgtg
     2941 cggcagctgt gcaaacaggc ccccagcatg tccgtgctgc tgctcagccc ccagcccact
     3001 ggcagtgtcc tgtgtgcctg ccaggtggcc cagggtgcca cacctacctt cacagctgag
     3061 gcctgggccc tagctgtgtg cagccacatg ggaggcaagg cttggggctc tccagtgata
     3121 gcccagggta ctggacacac tgctgacctg gaggctgccc tcaggacagc ccgagcttat
     3181 gcactcaacc agctctgacg aggcccaccc aggacacaga ggaatagaag gcaggcaagc
     3241 atctggagcc acataatctt cccggaggcg ggagcagagg accagcggct ggaggccagg
     3301 tctccgagcc aaagcagggc accagggcca ctgagaggcg agcaggaaga agtgtggatt
     3361 gaggggcagc aaccccagca aatggaagac ctgggctgct gtggttggga gcacccattc
     3421 aaagtgtttc accggctgca gactcagctc agtggttaag agcacttgtt cctagaaggg
     3481 acccaggttc ggttcccagc atccacatgg aggttcccca ccccatcagg caccagaaat
     3541 acatgtggta cacagacata catgtaggca ctcgtgtata cagacactca tacatgcaaa
     3601 gtaataaaac aatttttttt tctttttttc ggagctgggg accgaaccca gggccttgcg
     3661 cttgctaagc aagcgctcta ccgcggagct aaatccccaa ccccataaaa caattttttt
     3721 aaaaaagtgt ttcacagagc attagaagtc ctagaaaagt ctgtctgtgg gaaaaagagt
     3781 ggcctgcccg tctgtgcttc cggaggccca aggtgagctc ccagcagcca tatatggctc
     3841 acagtcgctt ttaactccac cagcagcaag cctgttgcct ttttctggat tctgtggcct
     3901 ttgcaaatat gtgacataaa aaaaaaaaaa aaaagaaaga aagaaagaaa gaaaaaaa
//
