LOCUS       NM_012039               2917 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus zw10 kinetochore protein (Zw10), mRNA.
ACCESSION   NM_012039 NM_029534
VERSION     NM_012039.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2917)
  AUTHORS   Park,Y., Kim,J.S. and Oh,J.S.
  TITLE     Zw10 is a spindle assembly checkpoint protein that regulates
            meiotic maturation in mouse oocytes
  JOURNAL   Histochem Cell Biol 152 (3), 207-215 (2019)
   PUBMED   31250100
  REMARK    GeneRIF: results demonstrate that Zw10 is localized at kinetochores
            and functions as an essential spindle assembly checkpoint component
            in mouse oocytes
REFERENCE   2  (bases 1 to 2917)
  AUTHORS   Starr,D.A., Williams,B.C., Li,Z., Etemad-Moghadam,B., Dawe,R.K. and
            Goldberg,M.L.
  TITLE     Conservation of the centromere/kinetochore protein ZW10
  JOURNAL   J Cell Biol 138 (6), 1289-1301 (1997)
   PUBMED   9298984
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ172982.1, AK168479.1 and BC067405.1.
            
            On Mar 22, 2011 this sequence version replaced NM_012039.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC012435.1, AK145270.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-444               CJ172982.1         2-445
            445-2895            AK168479.1         414-2864
            2896-2917           BC067405.1         4934-4955
FEATURES             Location/Qualifiers
     source          1..2917
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 26.58 cM"
     gene            1..2917
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /note="zw10 kinetochore protein"
                     /db_xref="GeneID:26951"
                     /db_xref="MGI:MGI:1349478"
     exon            1..207
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..2442
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /note="ZW10 homolog, centromere/kinetochore protein"
                     /codon_start=1
                     /product="centromere/kinetochore protein zw10 homolog"
                     /protein_id="NP_036169.1"
                     /db_xref="CCDS:CCDS23161.1"
                     /db_xref="GeneID:26951"
                     /db_xref="MGI:MGI:1349478"
                     /translation="MASFVTEVLAHSGSLEKEDLGTRISRLTRRVEEIKGEVCNMISK
                     KYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQQLERD
                     SVVLTLLKQLQEFSSAIEEYNSALAEKKYIPAARHLEEAQECLKLLKSRKCFDLKMLK
                     SLSMELTVQKQNILYHLGEDWQKLVVWKFPPAKDTSSLESCLQTELHLCTEQPEKEDM
                     TPLPSISSVLLAFSILGELPTKLKSFGQMLLKYILKPLVTCPSLHAVIERQPSSVSIC
                     FESLTTDLEHPSPPEAFAKIRLVLEVLQKQLLDLPLDADLEIGKVPGIVLAEMLGEGI
                     WEDLSECLIRNCLVYSIPTNSSKLQEYEEIIQSTEEFEKFLKEMRFLKGDTTDLLKYA
                     RNINSHFANKKCQDVIVAARNLMTSEIHNTVKIGPDCKEALPDLPSPDADHKLQVQTV
                     CKAQFTDAGNLEPETSLDPQSFSLPTCRISEAVKKLMELAYQTLLEATTSSDQCAVQL
                     FYSVRNIFHLFHDVVPTYHKENLRKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAPI
                     LCDGTTTFVDLVPGFRRLGTECFLAQMQAQKGELLERLSSARSFANMDDEENYSAASK
                     AVRQVLHQLRRLGIVWQDVLPVNIYCKAMGTLLNTAIAEMMSRITALEDISTEDGDRL
                     YSLCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDR
                     WADGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK"
     exon            208..342
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            343..444
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            445..522
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            523..682
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            683..835
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            836..1027
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1191
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1374
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1613
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1685
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1855
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1986
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1987..2118
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            2119..2321
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     exon            2322..2896
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2875..2880
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /note="hexamer: AGTAAA"
     polyA_site      2896
                     /gene="Zw10"
                     /gene_synonym="6330566F14Rik; MmZw10"
                     /note="major polyA site"
ORIGIN      
        1 agtttcccgg caggccctgc ggtgaggccg ctggcgggac cggagctgcg gcgctggcag
       61 cggggttgac ctatcctgtt tgtgtgggta cgcttcgtgg cgatggcctc tttcgtgaca
      121 gaagtcttgg cccactcggg gagcctggag aaggaggatc tgggcaccag gatcagccgc
      181 ctgacccggc gggtggagga gatcaagggt gaagtatgca atatgatcag caagaagtac
      241 agtgagttcc tgcctaccat gcagagtgcg caggccctag ttacccaggt ggacactcta
      301 tctaacgaca tcgaccagct gaaatccagg atagagactg aggtctgtcg ggatcttcac
      361 atatcaactg ttgagtttac aaacctgaag cagcagctgg aaagagactc tgtagtccta
      421 actctgctca aacaactcca agagttttcc tctgctattg aagagtataa cagtgcgtta
      481 gcagagaaga agtacatccc tgctgctcgg cacctggagg aggctcagga gtgcttgaag
      541 ttattaaagt ccagaaaatg ctttgactta aaaatgttga agtctctcag catggagctc
      601 accgtgcaga agcagaacat actgtaccac ctgggagaag actggcagaa gctggttgta
      661 tggaagtttc cgccggcaaa agataccagc agcttagagt cttgtctaca aacagagctt
      721 catttatgca ctgagcagcc ggagaaagag gacatgactc ctctgccgtc catcagttct
      781 gtcctcttgg ccttttccat tcttggagaa ttacccacca agctgaagtc atttggtcag
      841 atgctgctga agtatatcct taagcctctg gtgacctgcc cgtcgctcca tgctgtgatt
      901 gaaaggcagc caagttcagt tagcatttgt ttcgagtctc tgacgacgga cttggaacac
      961 ccatcaccac ccgaagcttt tgcaaagatc cgattggtcc tggaagtgct ccagaaacag
     1021 cttctagatt tgcctcttga tgctgaccta gaaattggaa aagtccctgg gatcgtgttg
     1081 gctgagatgc ttggtgaggg gatctgggag gacctttctg agtgcctcat cagaaactgc
     1141 ttggtttact ctattcccac aaacagcagc aagctccagg aatacgaaga gattatacag
     1201 tccacagaag aatttgaaaa gttcctaaag gagatgaggt ttttaaaagg cgatactact
     1261 gacttgctga aatatgctcg caatatcaat tctcattttg ctaataagaa gtgccaggat
     1321 gtgattgtgg cggctagaaa tctcatgacc tctgagattc acaacactgt caagattggt
     1381 cccgattgta aggaagcctt accagactta cccagtcctg atgctgatca caagctacaa
     1441 gtacagacgg tctgcaaagc gcagttcacc gacgccggga acctagagcc tgagacttct
     1501 ctggaccctc agtccttttc tttacccacg tgccgcatca gcgaggctgt gaagaagtta
     1561 atggagctcg cttatcagac tttacttgag gcaacaacaa gtagcgacca atgtgctgtc
     1621 cagctcttct actcagtgag gaatatcttc catttgttcc atgatgtggt accaacatac
     1681 cacaaggaga accttcggaa gctcccccag ttggctgcca ttcaccacaa caactgcatg
     1741 tatattgctc accacttgct gaccctcggt catcagttca gattgcggct cgcccccatc
     1801 ctttgcgatg gcacgaccac ctttgtggat cttgtacctg gcttcagaag acttgggacg
     1861 gagtgctttt tggcccaaat gcaggcacag aaaggagaac ttctggagag attgtcaagt
     1921 gctagaagct ttgcgaacat ggacgacgaa gagaattact ctgcagcgag caaggcagtg
     1981 aggcaggtgc tgcaccagct aaggagactt gggatcgtgt ggcaggatgt cctgccagtg
     2041 aacatatact gcaaggccat ggggaccttg ctgaacacag cgattgctga gatgatgagc
     2101 aggatcactg ctctagagga catctcgact gaagatggtg atagattgta ttccctgtgc
     2161 aaaacagtga tggatgaagg tccacaagtg tttgcacctc tgtctgatga aaacaaaaac
     2221 aagaaatacc aagaagaggt tcccgtctat gtgtccaaat ggatgccttt caaagaactc
     2281 atgataatgc tacaagctag cttgcaagaa attggagatc ggtgggcaga tggaaaaggg
     2341 cccctggcaa ctgcattccc ttccagcgaa gtcaaagctt taatccgtgc cttgttccag
     2401 aacacagaaa gaagagcagc tgcccttgct aagattaaat agctcctcct tggagaaagg
     2461 ctctcctgac tctgggttcc tcctttggtg taattatttc cttcaaaacc tctcggaatt
     2521 acttgttggt tttggtgagc cagtatatca tggaagcgta acttcacata aggacatcct
     2581 tgcctggacg aaggttttct gaactggaca ttacgatgat caatttacgc aaagcactgg
     2641 tgggttcatt gactgtcgct gctgtccctt gtcaagtatg agtctgctcc gcagtgtgat
     2701 ttgttcccag gccctcttga gagttgtata cattataatt ttagaccctg gctttggaca
     2761 ttccaaagtt agggttcaga atttgtaaaa tacgtttttt gaggggggtg ggcattaagg
     2821 gcacattact tgttcttaca agaattacag aaacctctta aaatatttct ttccagtaaa
     2881 tgcctttcag agttgaaaaa aaaaaaaaaa aaaaaaa
//
