LOCUS       NM_001359455            2180 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus zinc finger containing ubiquitin peptidase 1 (Zup1),
            transcript variant 1, mRNA.
ACCESSION   NM_001359455 XM_006512867
VERSION     NM_001359455.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2180)
  AUTHORS   Li,T. and Li,S.
  TITLE     MAVS promotes interferon signaling in RNA virus infection by
            ZUFSP-mediated chromatin regulation
  JOURNAL   Int Immunopharmacol 131, 111819 (2024)
   PUBMED   38460305
  REMARK    GeneRIF: MAVS promotes interferon signaling in RNA virus infection
            by ZUFSP-mediated chromatin regulation.
REFERENCE   2  (bases 1 to 2180)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077304.1, AK077730.1 and AV316666.1.
            
            On Jan 4, 2018 this sequence version replaced XM_006512867.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089514.1, AK077304.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AK077304.1         2-27
            27-1758             AK077730.1         1-1732
            1759-2175           AK077304.1         1760-2176
            2176-2180           AV316666.1         180-184
FEATURES             Location/Qualifiers
     source          1..2180
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 18.85 cM"
     gene            1..2180
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /note="zinc finger containing ubiquitin peptidase 1"
                     /db_xref="GeneID:72580"
                     /db_xref="MGI:MGI:1919830"
     exon            1..129
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            130..246
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            247..816
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1994
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /EC_number="3.4.19.12"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger with UFM1-specific peptidase domain protein;
                     lys-63-specific deubiquitinase ZUFSP; ubiquitin
                     carboxyl-terminal hydrolase ZUFSP"
                     /codon_start=1
                     /product="zinc finger-containing ubiquitin peptidase 1
                     isoform 1"
                     /protein_id="NP_001346384.1"
                     /db_xref="CCDS:CCDS87987.1"
                     /db_xref="GeneID:72580"
                     /db_xref="MGI:MGI:1919830"
                     /translation="MLSCNICGETVNSEPDMKAHLIVHMENEIICPFCKLSGINYNEI
                     CFHIETVHFEQNAPEKNSEKLAAVQYGHSDRKNTNLQSTAEVTSGIHSACASSFPKES
                     SESLPKDRTVKHEAFYTENITESRKYQKSREKKPGLSEAQGSIYETTYSPPECPFCGK
                     IEGCSQDMEIHVKTKHASLLESPLKDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEES
                     SFQQGMDRVQCSSDRELAHRLQQEEDRKRKSEESRQEREEFQKLQRQYGLDNSGGYKQ
                     QQLRHMELEVNRGRMHPSEFHSRKADMLESIAIGIDDGKTKTSGIIEALHRYYQNTAT
                     DVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQSDVYGDCLKGMAVPCIPKI
                     QSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLRVKCRIIDFHKSTGP
                     LGTHPRLFEWILNYYSSETEGTPKIVCTSKPPIYLQHQGHSRTVVGIEEKKNRTLCLL
                     VFDPGCPSREMQKLLKQDMEASSLRQLRKSVGNLKHKQYQIVAVEGVLSPEEKVARKQ
                     ASQVFTAEKIP"
     exon            817..927
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1049
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1218
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1407
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1573
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1725
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1946
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2180
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2156..2161
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /note="hexamer: AATAAA"
     polyA_site      2180
                     /gene="Zup1"
                     /gene_synonym="2700019D07Rik; DUB; Zufsp"
                     /note="major polyA site"
ORIGIN      
        1 agacggatct gcagcggggc atgctgggat ctctaccctc tctggccagt gaggaaggtc
       61 tgttgtgact gcggaggact cttggaggcc tgggctctct tttgggtcgc ggcgcggcag
      121 tctcgggagt gtgccagtgt tttgactgtc ctacatcgtg tgatcaggca tagatccact
      181 tgggacctgt ctgctcagaa ggtttgagat caggcataga tccactggga catgtcagct
      241 cagaaggccc atgctctgcc atgctttcct gcaacatatg tggtgaaact gtaaactcag
      301 aaccagatat gaaagctcac ctaattgttc acatggaaaa tgaaattatc tgtccatttt
      361 gcaagttgtc aggtataaat tacaacgaaa tatgttttca tatcgaaact gttcattttg
      421 aacaaaatgc accagaaaaa aactctgaga agctagctgc agtgcaatat ggacattcag
      481 accgaaagaa caccaacctg cagagtacag cggaagttac ttcaggcatt cattcagctt
      541 gtgcatctag ctttccaaaa gagtcatctg aaagccttcc taaagatagg actgtaaagc
      601 atgaagcttt ttatacagag aacataactg aatctagaaa gtaccaaaag agcagagaaa
      661 agaagcctgg attgtctgag gcccaaggat caatttatga aacaacatac agtcctcccg
      721 aatgtccatt ttgtggaaaa attgaggggt gtagtcaaga tatggaaatt catgtgaaaa
      781 caaagcatgc cagtctttta gaaagtccat taaaagactg tcatcaacca ctctatgact
      841 gtcccatgtg tgggcttgtc tgtacaaatt accatattct ccaggaacat gtggacttgc
      901 atttagaaga aagcagcttt cagcaaggca tggacagagt ccagtgttct agtgatagag
      961 aattagctca ccggcttcag caagaagaag acagaaagag gaaatctgaa gaatcaagac
     1021 aagaaaggga agagtttcag aagttgcagc ggcaatatgg tttagataat tctggaggat
     1081 acaaacaaca gcagctacga catatggagc tagaagtaaa taggggaaga atgcatccat
     1141 ctgaatttca tagcagaaaa gctgacatgt tggaatcaat agctattggt attgatgatg
     1201 gaaaaacaaa aacttctgga attattgaag ccctccatag gtattatcag aacactgcca
     1261 cagatgtaag gtgtgtgtgg ctttctacag tggtggatca ctttcactca tcttttgggg
     1321 acaaaggttg gggttgcggt tatagaaact tccagatgct actttcatca ttattgcaaa
     1381 gtgatgtata tggtgactgc ttgaaaggta tggcagttcc ttgtattcca aaaattcagt
     1441 ccatgattga agatgcatgg aatgaaggtt ttgatcctca gggagcctct caacttaata
     1501 acaaattaca gggaacaaag gcctggattg gagcgtgtga gatttataca cttctgacct
     1561 cactgagagt aaagtgccgc attattgatt ttcacaagtc aactggtcct ttgggtacac
     1621 accctcgctt atttgaatgg atattgaact attattcttc agagacggaa ggaactccaa
     1681 agatcgtgtg tacatctaaa cctcctatct atctccagca tcagggtcac agtcgaacag
     1741 ttgttggaat tgaagagaaa aaaaaccgaa cattatgctt gctagtattt gatcctggat
     1801 gtccttctcg agaaatgcag aaactgttaa agcaagatat ggaggctagt agtcttagac
     1861 aacttcggaa atctgtggga aatctaaaac ataagcagta ccagatagta gcagtagagg
     1921 gtgttctttc cccagaggaa aaagttgcca ggaaacaagc ttcgcaagtg tttacagcgg
     1981 agaagattcc ttgacccaaa tattttcatg attttgtaat tatccttttt ttccctgata
     2041 atgaactctg atagagtttg aagaatttat ttcacttaag tccttgatat gttatttaag
     2101 ttataatgcc tattaagtta tacttcttag catttcattg tctagtaatt agttgaataa
     2161 aattccttgt ttgctttgtt
//
