LOCUS       NM_027964               2073 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus zinc finger SWIM-type containing 2 (Zswim2),
            transcript variant 1, mRNA.
ACCESSION   NM_027964
VERSION     NM_027964.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2073)
  AUTHORS   Nozawa,K., Fujihara,Y., Devlin,D.J., Deras,R.E., Kent,K.,
            Larina,I.V., Umezu,K., Yu,Z., Sutton,C.M., Ye,Q., Dean,L.K.,
            Emori,C., Ikawa,M., Garcia,T.X. and Matzuk,M.M.
  TITLE     The testis-specific E3 ubiquitin ligase RNF133 is required for
            fecundity in mice
  JOURNAL   BMC Biol 20 (1), 161 (2022)
   PUBMED   35831855
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2073)
  AUTHORS   Nishito,Y., Hasegawa,M., Inohara,N. and Nunez,G.
  TITLE     MEX is a testis-specific E3 ubiquitin ligase that promotes death
            receptor-induced apoptosis
  JOURNAL   Biochem J 396 (3), 411-417 (2006)
   PUBMED   16522193
  REMARK    GeneRIF: MEX(identical to Zswim2) has homology to MEKK1 & is
            expressed uniquely in testis. MEX has 4 putative zinc-binding
            domains including an N-terminal SWIM (SWI2/SNF2 & MuDR) domain of
            unknown function & 2 RING fingers separated by ZZ zinc finger
            domain
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772256.15.
            
            On Mar 23, 2023 this sequence version replaced NM_027964.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC120837.1, AK006367.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               AL772256.15        108009-108223       c
            216-292             AL772256.15        106622-106698       c
            293-333             AL772256.15        105728-105768       c
            334-544             AL772256.15        92057-92267         c
            545-796             AL772256.15        90564-90815         c
            797-881             AL772256.15        87658-87742         c
            882-991             AL772256.15        84889-84998         c
            992-1145            AL772256.15        83840-83993         c
            1146-2073           AL772256.15        82065-82992         c
FEATURES             Location/Qualifiers
     source          1..2073
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.33 cM"
     gene            1..2073
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /note="zinc finger SWIM-type containing 2"
                     /db_xref="GeneID:71861"
                     /db_xref="MGI:MGI:1919111"
     exon            1..215
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            216..292
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            293..333
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            334..544
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            545..796
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            797..881
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            882..991
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            992..1145
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..2073
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1922..1927
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /note="hexamer: AATAAT"
     polyA_site      1955
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
     regulatory      2046..2051
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /note="hexamer: TATAAA"
     polyA_site      2073
                     /gene="Zswim2"
                     /gene_synonym="1700025P14Rik; 4933437F18Rik; MEX"
                     /note="major polyA site"
ORIGIN      
        1 atagagaccc aaggcgcctc agaaagctag aggctccacg gccgccaggg atgcttcgcg
       61 gaggctgtaa agcctcagaa aagcgaagac acttaagcga gagcctcagc tggcagcaag
      121 accaggcgct gagtagcagc atctatctcc tgcgacagat cggccccaca ggcttcctac
      181 tgaaggagga ggagccagaa aagggggatt tccgagtttt gcttggaaac ccacatgagt
      241 gcagctgccc cacgtttctg aagagggggg aactgtgcaa gcacatatgc tgggtgttat
      301 tgaaaaaatt caagcttcca aggaatcatg aatctgcttt tcagttgggt cttaccgaag
      361 gagaaataaa tgacttgctc cgggggatac atcaggtcca agctccacag cttagagcaa
      421 gtgatgagac tgcacaggtg gaagaagacg gctaccttaa gcagaaggac atcaatgcag
      481 gggatatctg tcctatttgt caagaagtgc tgctggagaa aaaactccct gtcaccttct
      541 gcagatttgg ttgtggcaat aatgttcaca taaaatgcat gcggatcttg gctaactacc
      601 aagacacagg gtctgacagt tccgtgttaa gatgtccgct gtgcagagaa gagtttgcac
      661 cactaaaagt tatcttggag gagttcaaaa actctaacaa actcataact atatctgaga
      721 aagaacgact ggacaaacac ctcggaattc cctgtaataa ctgtaaccaa ctgccaatcg
      781 aggggaggtg ctacaagtgt actgagtgtg tggagtacca cttatgccag gagtgctttg
      841 acagctgctg tcactcttcc catgcctttg cgtcccgtga gaaaagaaac caaagatgga
      901 gatcagtaga aaaaagatca gaagtcatga aatatttaaa tactgaaaat gagggtgaag
      961 caaagccggg atgttttcaa gaaaagcagg gtcagtttta cacaccgaag catgttgtaa
     1021 agtctctgcc tctcctgatg attacaaaga agagcaagct gctggcccca gggtaccagt
     1081 gtcgactttg cttgaaatca ttttcttttg gtcaatatac aagactgcta ccatgtactc
     1141 acaagtttca caggaaatgt attgacaatt ggttactcca caagtgcaat tcatgcccga
     1201 ttgacagaca agtcatatat aaccctctga tctggaaagg catagccacg gatggacaag
     1261 cacatcagtt ggcttcaagc aaagatatcg cctgtctgtc gaagcagcaa gagccaaaac
     1321 tttttattcc tggtactgga ttagttttaa aaggaaagag aatgggggtt ttacctagca
     1381 ttccccagta taattctaaa gtattgacta cacttcaaaa tccatcagac aactatcaga
     1441 atataacaat ggacgaccta tgctcagtca aattagataa ttcaaattcc agaaaattag
     1501 tttttggata taaaattagc aaacagttcc ccacatatct gaaaaatcca accactgggc
     1561 aaacaccatc tcaaacattt cttccttccc ttcctcataa gaacattatt tgtctcactg
     1621 gaagggaaag cccacatatc tatgaaaaag atcatattgg tcagagtcaa aagacaagca
     1681 gaggttacga acatataaac tataacacaa ggaaatctct tggttctaga ttaagacaac
     1741 acaagagatc aagtgcatta tcttcagaag atttaaatct tactatcaac ttgggtacaa
     1801 ccaaacttag tttgtctaag aggcaaaata attccatggg gaaagttaga caaaaacttg
     1861 gtcatccacc cagacgacct gcgtatcccc ctttacaaac acaaaatgct gctctgtctt
     1921 taataatgca aggaattcaa ctctgaaaaa aaacagtttt attacacctg aaaaaatgaa
     1981 tatttaatat gcaaaatatt ttatttgtaa cacataagaa tccatgtaca tccttgacaa
     2041 atatatataa aatactctat tgtcattttt gcc
//
