LOCUS       NM_001100186            1992 bp    mRNA    linear   ROD 26-JUN-2024
DEFINITION  Mus musculus zinc finger and SCAN domain containing 4D (Zscan4d),
            mRNA.
ACCESSION   NM_001100186 XM_620418 XM_899474 XM_919959 XM_919970
VERSION     NM_001100186.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1992)
  AUTHORS   Lamacova,L., Jansova,D., Jiang,Z., Dvoran,M., Aleshkina,D.,
            Iyyappan,R., Jindrova,A., Fan,H.Y., Jiao,Y. and Susor,A.
  TITLE     CPEB3 Maintains Developmental Competence of the Oocyte
  JOURNAL   Cells 13 (10), 850 (2024)
   PUBMED   38786074
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1992)
  AUTHORS   Shi,F., Xu,Y., Zhang,S., Fu,Z., Yu,Q., Zhang,S., Sun,M., Zhao,X.
            and Feng,X.
  TITLE     Decabromodiphenyl ethane affects embryonic development by
            interfering with nuclear F-actin in zygotes and leads to cognitive
            and social disorders in offspring mice
  JOURNAL   FASEB J 36 (8), e22445 (2022)
   PUBMED   35816173
REFERENCE   3  (bases 1 to 1992)
  AUTHORS   Smith,R., Susor,A., Ming,H., Tait,J., Conti,M., Jiang,Z. and
            Lin,C.J.
  TITLE     The H3.3 chaperone Hira complex orchestrates oocyte developmental
            competence
  JOURNAL   Development 149 (5) (2022)
   PUBMED   35112132
REFERENCE   4  (bases 1 to 1992)
  AUTHORS   Liu,Y., Sun,J., Su,Y., Lin,J., Lv,C., Mo,K., Xu,S. and Wang,S.
  TITLE     Nuclear-localized eukaryotic translation initiation factor 1A is
            involved in mouse preimplantation embryo development
  JOURNAL   J Mol Histol 52 (5), 965-973 (2021)
   PUBMED   34405343
REFERENCE   5  (bases 1 to 1992)
  AUTHORS   Rong,Y., Ji,S.Y., Zhu,Y.Z., Wu,Y.W., Shen,L. and Fan,H.Y.
  TITLE     ZAR1 and ZAR2 are required for oocyte meiotic maturation by
            regulating the maternal transcriptome and mRNA translational
            activation
  JOURNAL   Nucleic Acids Res 47 (21), 11387-11402 (2019)
   PUBMED   31598710
REFERENCE   6  (bases 1 to 1992)
  AUTHORS   Eckersley-Maslin,M.A., Svensson,V., Krueger,C., Stubbs,T.M.,
            Giehr,P., Krueger,F., Miragaia,R.J., Kyriakopoulos,C.,
            Berrens,R.V., Milagre,I., Walter,J., Teichmann,S.A. and Reik,W.
  TITLE     MERVL/Zscan4 Network Activation Results in Transient Genome-wide
            DNA Demethylation of mESCs
  JOURNAL   Cell Rep 17 (1), 179-192 (2016)
   PUBMED   27681430
REFERENCE   7  (bases 1 to 1992)
  AUTHORS   Nakai-Futatsugi,Y. and Niwa,H.
  TITLE     Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic
            Stem Cells
  JOURNAL   Stem Cell Reports 6 (4), 483-495 (2016)
   PUBMED   26997646
  REMARK    GeneRIF: Data show that zinc finger protein 42 (Rex1) and zinc
            finger and SCAN domain containing 4D/4C (Zscan4D/4C) correlate with
            the cell-cycle length under different mechanisms.
REFERENCE   8  (bases 1 to 1992)
  AUTHORS   Amano,T., Hirata,T., Falco,G., Monti,M., Sharova,L.V., Amano,M.,
            Sheer,S., Hoang,H.G., Piao,Y., Stagg,C.A., Yamamizu,K., Akiyama,T.
            and Ko,M.S.
  TITLE     Zscan4 restores the developmental potency of embryonic stem cells
  JOURNAL   Nat Commun 4, 1966 (2013)
   PUBMED   23739662
  REMARK    GeneRIF: These results indicate the active roles of Zscan4 in the
            long-term maintenance of embryonic stem cell potency.[Zscan4]
REFERENCE   9  (bases 1 to 1992)
  AUTHORS   Sonehara,H., Nagata,M. and Aoki,F.
  TITLE     Roles of the first and second round of DNA replication in the
            regulation of zygotic gene activation in mice
  JOURNAL   J Reprod Dev 54 (5), 381-384 (2008)
   PUBMED   18580041
  REMARK    GeneRIF: Inhibiting the first round increased the expression levels
            of hsp70.1, eif-1a and zscan4d but decreased that of muerv, while
            inhibiting the second round increased the expression levels of all
            four genes.
REFERENCE   10 (bases 1 to 1992)
  AUTHORS   Falco,G., Lee,S.L., Stanghellini,I., Bassey,U.C., Hamatani,T. and
            Ko,M.S.
  TITLE     Zscan4: a novel gene expressed exclusively in late 2-cell embryos
            and embryonic stem cells
  JOURNAL   Dev Biol 307 (2), 539-550 (2007)
   PUBMED   17553482
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF143406.1.
            
            On or before Jul 30, 2007 this sequence version replaced
            XM_919970.2, XM_919959.2, XM_899474.2, XM_620418.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF143406.1, SRR17253012.948797.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849383 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1992
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="B6D2F1/J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 6.86 cM"
     gene            1..1992
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /note="zinc finger and SCAN domain containing 4D"
                     /db_xref="GeneID:545913"
                     /db_xref="MGI:MGI:3645954"
     exon            1..96
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /inference="alignment:Splign:2.1.0"
     exon            97..568
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /inference="alignment:Splign:2.1.0"
     CDS             194..1714
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /codon_start=1
                     /product="zinc finger and SCAN domain containing protein
                     4D"
                     /protein_id="NP_001093656.1"
                     /db_xref="CCDS:CCDS52013.1"
                     /db_xref="GeneID:545913"
                     /db_xref="MGI:MGI:3645954"
                     /translation="MASQQAPAKDLQTNNLEFTPSHSSGVQWVEDISNSPSAQLNFSP
                     SNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLIGHCKDKYALTEKWK
                     ASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPT
                     PDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQY
                     PEHEEGNVVFQFPLDARRASQGNSSHHVDFRSAPTPADVPMEEQPKDLSRENISEDKN
                     NCYNTSRNAATQVYRSDNIPRKKTDSLSINKRIYHSEPEEGDIPYGVPQDSTRASQGT
                     STCLQESLGECFSEKDPRELPGLESRQEEPISDPVFLGKDHEANLPCESHQKRFRRDA
                     KLFKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEK
                     PFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD"
     exon            569..728
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /inference="alignment:Splign:2.1.0"
     exon            729..1992
                     /gene="Zscan4d"
                     /gene_synonym="EG545913"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccctggg cttcttggca tcacccttga agttcactgg acaaagaggt gaggtggagg
       61 agtaggtaaa cttcccttcc tagtggtcgt gaatgtcttt tacagtacat ccatcaactg
      121 ttagcatttt cataaagtca caaaacagat actaaactgc tatagttgaa tctttcacac
      181 cattgtcacc acaatggctt cacagcaggc accagcaaaa gaccttcaga ccaacaattt
      241 agagtttact ccatctcata gttctggtgt gcagtgggta gaagacatct ctaactcacc
      301 aagtgctcag ctaaactttt ctccaagtaa caatggctgc tgggcaactc aggagctgca
      361 aagtctctgg aagatgttca actcctggtt gcagccagaa aagcagacta aggagcagat
      421 gatttctcaa ctggtcttgg agcagtttct cctcattggg cactgcaagg acaagtatgc
      481 tttgacagag aagtggaaag ccagtggtag cgatatgagg agattcatgg agagtctgac
      541 tgatgagtgc ttgaagcctc ctgtcatggt ccatgtttca atgcaaggac aagaagctct
      601 cttttctgaa aacatgccat taaaagaagt catcaagctt ttgaaacaac agcaatctgc
      661 aacaaggcca acaccagata atgagcagat gccagtagac accacacaag atagattatt
      721 ggccacagga caagaaaaca gtgaaaatga atgcaacaac tcttgtaatg ctactgaagc
      781 aaatgttggt gaaagctgta gtggaaatga aatggactcc cttcttatta tccagaaaga
      841 acagtaccct gagcatgaag aggggaatgt tgtttttcaa ttccctcttg atgccagaag
      901 agcaagtcaa ggcaactcca gtcatcatgt agacttccgg agtgctccga ctcctgcgga
      961 tgtccccatg gaggaacaac caaaggattt atccagagaa aacatctctg aggacaagaa
     1021 caattgctat aacacttcca ggaatgcagc tactcaagta tatagaagtg ataatattcc
     1081 caggaaaaag acagactccc tttccattaa caagagaata tatcattctg agcctgagga
     1141 gggagatatt ccttatggag ttcctcagga ttctacaaga gcaagtcaag gaacatctac
     1201 atgcttgcaa gagtcacttg gggaatgttt ttctgaaaaa gaccctaggg agctaccagg
     1261 gttggagtct aggcaagagg agcctatctc tgatcctgtc tttcttggta aggatcatga
     1321 ggcaaactta ccatgtgaaa gtcatcaaaa gagattccgt agagatgcca aactattcaa
     1381 gtgtgaagaa tgttctagga tgttcaaaca tgccaggagc ctttcgtccc accagagaac
     1441 tcacctgaat aagaagagtg aattgctttg tgtcacctgt cagaaaatgt tcaaacgagt
     1501 ctctgaccgc cgaacccatg agatcataca catgccagaa aagcctttca agtgcagcac
     1561 atgtgaaaag tccttcagcc acaagaccaa cctgaagtct catgagatga ttcacacagg
     1621 agaaatgcct tatgtctgtt ccctatgtag ccgtcgcttt cgccaatcat ccacttacca
     1681 tcgtcacctg aggaattacc acagatctga ctgaagtatc taacatcctc agcagagact
     1741 ggtagggctt cagcctcagt atgtcatctt caaagagaga agaatgttgc aagtaaattg
     1801 tactgtccca ataatgatat aacatgcttg tggattgcca cttttatgtt ttgtttttta
     1861 ttgtgtgtgt gtgtgtatgt aattttttgt ctgtaatttc catagttcca cagcataagt
     1921 tattagaata ctttgctgtt aattcttgag ttgcttcttg cttttagaca gtgtctttct
     1981 ggttggcagc tt
//
