LOCUS       NM_027678               4224 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, RAN-binding domain containing 3 (Zranb3),
            transcript variant 1, mRNA.
ACCESSION   NM_027678 NM_172642 XM_129483 XM_885707 XM_896374 XM_896396
            XM_896419 XM_896436 XM_912948 XM_922552 XM_922558 XM_922565
            XM_922581 XM_922587 XM_922596 XM_974893 XM_974926 XM_974968
            XM_975006 XM_975040 XM_975084
VERSION     NM_027678.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4224)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4224)
  AUTHORS   Puccetti,M.V., Adams,C.M., Kushinsky,S. and Eischen,C.M.
  TITLE     Smarcal1 and Zranb3 Protect Replication Forks from Myc-Induced DNA
            Replication Stress
  JOURNAL   Cancer Res 79 (7), 1612-1623 (2019)
   PUBMED   30610086
REFERENCE   3  (bases 1 to 4224)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   4  (bases 1 to 4224)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129545.5, AK084943.1, BC066035.1 and AC131995.14.
            
            On Oct 26, 2013 this sequence version replaced NM_027678.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC066035.1, AK083641.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AC129545.5         27606-27623
            19-223              AK084943.1         3-207
            224-4217            BC066035.1         161-4154
            4218-4224           AC131995.14        118836-118842       c
FEATURES             Location/Qualifiers
     source          1..4224
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 55.8 cM"
     gene            1..4224
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /note="zinc finger, RAN-binding domain containing 3"
                     /db_xref="GeneID:226409"
                     /db_xref="MGI:MGI:1918362"
     exon            1..219
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            220..387
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     CDS             227..3436
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger Ran-binding domain-containing protein 3; annealing
                     helicase 2; DNA annealing helicase and endonuclease
                     ZRANB3"
                     /codon_start=1
                     /product="DNA annealing helicase and endonuclease ZRANB3
                     isoform 1"
                     /protein_id="NP_081954.1"
                     /db_xref="CCDS:CCDS35697.1"
                     /db_xref="GeneID:226409"
                     /db_xref="MGI:MGI:1918362"
                     /translation="MPTAGSKKKAPTPQISCLTSESYTQLDFLPDKLRTKLLPFQKDG
                     IVFALRRDGRCMVADEMGLGKTIQAIAIAYFYKEEWPLLIVVPSSLRYPWIEELEKWI
                     PELEPEEINVVMNKTDIGRIPGSRVTVLGYGLLTTDAETLLDALNTQNFRVVIVDESH
                     YMKSRTAARSKILLPMVQKARRAILLTGTPALGRPEELFMQIEALFPQKFGTWIEYAK
                     RYCNAHVRYFGKRRQWDCRGASNLSELHQLLNDIMIRRLKSEVLSQLPPKVRQRIPFD
                     LPPAAVKELNASFEEWQKLMRAPNSGAMETVMGLITRMFKQTAIAKAGAVKDYIKMLL
                     QNDSLKFLVFAHHLSMLQACTEAVIESKSRYIRIDGSVPSSERIHLVNQFQKDPDTRV
                     AILSIQAAGQGLTFTAASHVVFAELYWDPGHIKQAEDRAHRIGQCSSVNIHYLIANGT
                     LDSLMWAMLNRKAQVTGSTLNGRKEKLQATEDDKEKWGFLQFAEAWTPSDSFEELKDS
                     VFTHFEKEKQHDIRSFFLPKLKKRQLETTCDDPEAFKEKITVASDPRKMATSDSTADK
                     NGCEPEAKRLKSLSTEDHSSALEEGPSLQARATSMEVVHEVKPPLASPALPEKGWQCG
                     FCTFLNNPGLPYCEMCENPRSRAAGRNHLQDNNKNDEDAAQESTSKSDQAGLECERQC
                     PERLEAEQSANSKEEALEGGGEDRLPSQPEIGQLNNSGTLPVRETFMFCASRNTDRIH
                     LYTKDGKPMNCNFIPLDIKLDLWEDLPATFQLKQNRSLILRFVREWSSLTAMKQRVLR
                     KSGQLFCSPLLASEEITKQQAKENNTRRYITKEDVAKASMNKVKSDGGHIRLITKESM
                     TQDSSLKKIDSACVPSLNPCPADLTVEPSPSKGYIQAVDKEGRPLCLRCQHPTCQPEQ
                     TAKASAWDSRFCSLKCQEEFWIRSNNSYLRAQVFATEHGVCQHCGVDAQELFLRMRDA
                     PKSHRKSLLNAAWTAKLPLEQLNEMLRNPGEGHFWQVDHIRPVYEGGGQCSLDNLQTL
                     CTVCHKERTAQQAKERSQVRRLSLATKHGSDITRFLVKK"
     exon            388..406
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            407..585
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            586..817
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            818..903
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1075
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1076..1192
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1193..1312
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1432
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1612
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1762
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..2168
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2366
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2367..2458
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2560
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2561..2703
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2704..2814
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            2815..3205
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3337
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     exon            3338..4224
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4193..4198
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /note="hexamer: AATAAA"
     polyA_site      4219
                     /gene="Zranb3"
                     /gene_synonym="4933425L19Rik; AH2; C730006D09"
                     /note="major polyA site"
ORIGIN      
        1 ttccgcttag ttgaagacgc ttgcaaaaag tttggcggga gttgaagatt atgaagctag
       61 tgctgcattt tggcggactg tatagggcaa gagatgggaa attgactgca ctttaattgc
      121 gctataagaa aatagtgggt aacagtcggg cgtggtggct gatgcctgta acagctggaa
      181 gctgaaaggt cgccgcgagt tcatagcctg ggctacagag ctcaccatgc ctacagctgg
      241 tagcaagaag aaggctccca caccgcagat ttcttgttta acaagcgaat catatacaca
      301 gctggatttt ttaccggaca agcttagaac aaaactgctt ccgttccaaa aagatggcat
      361 cgtttttgcc ctcagaagag atggcaggtg tatggtggct gatgaaatgg gtctaggaaa
      421 gacaatccag gcgattgcaa ttgcttactt ctacaaagag gagtggcccc tgctgatagt
      481 cgtcccttca tctctaagat acccttggat agaagaacta gaaaaatgga tcccagagct
      541 agagccagag gaaatcaatg tcgtcatgaa caaaactgac attgggagaa tcccgggcag
      601 cagagtgaca gttctgggct acggtctctt aaccacagat gcagagactt tgctggatgc
      661 actgaacacg cagaacttca gggtcgtgat agtggatgag tcacactaca tgaagtccag
      721 aactgctgcc cgcagcaaga ttctcctgcc catggtgcag aaggccagga gagccattct
      781 tcttacagga accccagctc tgggaaggcc tgaggagctt ttcatgcaga ttgaggctct
      841 tttcccacaa aaatttggaa cttggattga gtatgctaaa agatactgca atgcacatgt
      901 cagatacttt ggcaaaaggc gtcagtggga ctgtagaggg gcatcaaacc ttagtgagct
      961 tcaccagctc ctaaatgaca taatgatcag aagactaaag agtgaagttt taagccagct
     1021 gcccccgaaa gtcagacagc gcattccctt tgaccttccc ccagcagctg tcaaggaact
     1081 gaatgccagc tttgaagaat ggcagaaact aatgagagct ccaaattcag gtgccatgga
     1141 gacggttatg gggttgataa cacgcatgtt caaacagact gcaattgcca aggcaggtgc
     1201 agtgaaggac tatattaaga tgctgcttca gaacgactcc cttaaatttc tggtctttgc
     1261 gcaccattta agtatgctcc aggcttgcac agaagcagtc atcgaaagca agtctcgtta
     1321 catcaggata gatggaagtg ttccatcttc agaaagaatt catctggtta atcaatttca
     1381 gaaggacccc gatactcgtg tggctatcct gagcattcag gctgctggcc agggtttaac
     1441 gtttactgct gcgagtcacg ttgtctttgc tgagttgtac tgggaccctg gacatatcaa
     1501 acaagcagaa gaccgagctc accgaatcgg acagtgcagt tctgtgaata ttcactacct
     1561 tattgcaaat ggtactctgg acagcctaat gtgggcaatg ctgaatcgaa aggctcaggt
     1621 cacagggagc acactgaatg gcaggaagga gaaactccag gctacggaag atgacaagga
     1681 gaagtggggt tttctgcagt ttgctgaagc atggacccca agtgacagtt ttgaagagct
     1741 caaggattct gtgtttactc actttgaaaa agagaaacag catgatattc gatcattctt
     1801 cttaccaaaa ctgaaaaaga gacagttaga aacgacctgt gatgacccag aggcattcaa
     1861 ggagaagatt acagtggcct cggaccctag aaaaatggct acaagtgata gcactgctga
     1921 caaaaatggg tgtgagcctg aagctaaaag gttgaagtcc ctgagcaccg aggaccacag
     1981 cagtgccctg gaggaaggac cgtccttgca agccagagcc acatccatgg aagttgtcca
     2041 tgaggtcaag cccccattgg cttctccagc ccttcctgag aagggatggc agtgtggctt
     2101 ctgcacattc ctcaacaacc caggccttcc atactgtgag atgtgtgaga accctcggag
     2161 cagagctgct ggccgcaacc atcttcagga taacaacaaa aatgatgaag acgctgctca
     2221 ggaaagcacc tccaaaagtg atcaagctgg tttggagtgt gaaaggcaat gccctgaacg
     2281 gttggaagct gagcagtcgg ctaatagcaa ggaagaggca ttggaaggtg gaggggaaga
     2341 cagactgcca tctcagccag agattgggca gttgaataat tcaggcactc tgccagtgcg
     2401 tgagaccttc atgttttgtg caagcagaaa caccgaccgg atccacctct ataccaagga
     2461 tggaaagcca atgaactgca attttattcc tttggatata aagttagacc tttgggaaga
     2521 cttaccagca acctttcaac tgaaacagaa tcgctctctg attctaaggt tcgtccgaga
     2581 gtggagtagt ctgactgcca tgaagcagag agttctcagg aaaagtggtc agctgttctg
     2641 cagcccactg ctggcttcgg aagagatcac aaagcaacaa gccaaggaaa ataatactag
     2701 aagatacatc actaaagaag atgttgccaa ggcttccatg aataaggtga aaagtgatgg
     2761 gggccacatc cgtctcatca ccaaggaatc catgacccag gactcttctc taaaaaagat
     2821 tgatagcgcc tgtgtcccat ctctgaatcc ctgcccagcg gatctcactg ttgagccatc
     2881 cccatccaaa ggctacattc aggcggtgga taaggaagga aggccactct gcctccgctg
     2941 ccagcatccc acctgccagc ctgagcaaac agccaaagcc agtgcctggg actcacggtt
     3001 ctgctccctg aaatgtcagg aagaattctg gatccgatcc aataacagtt acctgagagc
     3061 ccaggtgttt gcaacagaac atggtgtgtg tcagcactgt ggtgtggacg cacaggagct
     3121 ctttctgcgg atgagagatg cccctaaaag tcacaggaag agtctcctca atgctgcctg
     3181 gactgcaaaa ctcccactgg agcagctaaa tgagatgctg agaaacccag gagaaggcca
     3241 cttctggcag gtggatcaca tcaggccagt gtatgaggga ggtggacagt gctccctaga
     3301 caacctgcag accctctgca cagtgtgcca caaggagaga actgcccagc aagccaagga
     3361 aagaagtcag gtgagacgac tctctctggc aacaaagcac ggatcagaca tcacccggtt
     3421 tctggtgaag aagtaaggcg agatataaac agaagcagat ggcctgcagg cagaagcagt
     3481 tgtcacaatt catcttcatg tatgtctagt attttaagaa taggaagttt ttaaatataa
     3541 gtcaataact gaaatttaga tttttgctaa gctctcttag tgttacatac ttaacagaaa
     3601 ctgagggatg atgggaagat tctggggtct tcctgactca tgaagattgt caattatgtt
     3661 tcagcaagat tttgttccgc tttttttccc cttctacacc ttaatcactg cattgggcat
     3721 ggatagtgtg ggacaaatat attcacgcaa acctgacagc tcttgatcac cattgcttct
     3781 ggactgtgta gtataaaggg aacattccag aacaatcagg gacattttgg agacaagcca
     3841 tgattagtaa ggaatgatta cagctcaggc gcatgtttgg ggtgcagcct ccttgcttga
     3901 tttctgggcc agtcctcttc attgaagaga tgcttttgtt aatgaactga ttgtaagctc
     3961 acatggtgtc tgtgtacaac tgctgtgctc tgagtaacca tgagaacaag tgagagacca
     4021 cagtgccgca cagcctcgct tctgttttcc tgtttgctcc cttgtttcct gtcatggttt
     4081 gttttgtttt taatgtataa aatcaggcta attgtcaaaa cagattttgt ctcctggtcc
     4141 tcgtttcctg gttttaaaat cctggtagtg atttgttttg ttctgttctt tcaataaacc
     4201 ttgtaatttt ttaaaaatat tttt
//
