LOCUS       NM_001417872            2826 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zona pellucida like domain containing 1 (Zpld1),
            transcript variant 2, mRNA.
ACCESSION   NM_001417872 XM_006522132
VERSION     NM_001417872.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2826)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2826)
  AUTHORS   Vijayakumar,S., Jones,S.M., Jones,T.A., Tian,C. and Johnson,K.R.
  TITLE     Spontaneous mutations of the Zpld1 gene in mice cause semicircular
            canal dysfunction but do not impair gravity receptor or hearing
            functions
  JOURNAL   Sci Rep 9 (1), 12430 (2019)
   PUBMED   31455802
  REMARK    GeneRIF: Spontaneous mutations of the Zpld1 gene in mice cause
            semicircular canal dysfunction but do not impair gravity receptor
            or hearing functions.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155271.1.
            
            On Mar 10, 2023 this sequence version replaced XM_006522132.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2884349.1,
                                           SRR7652917.47632.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AC155271.1         178993-179069       c
            78-191              AC155271.1         177772-177885       c
            192-285             AC155271.1         140219-140312       c
            286-388             AC155271.1         139911-140013       c
            389-502             AC155271.1         124223-124336       c
            503-723             AC155271.1         108597-108817       c
            724-905             AC155271.1         105267-105448       c
            906-978             AC155271.1         103638-103710       c
            979-1076            AC155271.1         98366-98463         c
            1077-1157           AC155271.1         96853-96933         c
            1158-1329           AC155271.1         90524-90695         c
            1330-1438           AC155271.1         89237-89345         c
            1439-1468           AC155271.1         83963-83992         c
            1469-2826           AC155271.1         82204-83561         c
FEATURES             Location/Qualifiers
     source          1..2826
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 33.65 cM"
     gene            1..2826
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /note="zona pellucida like domain containing 1"
                     /db_xref="GeneID:239852"
                     /db_xref="MGI:MGI:2443415"
     exon            1..77
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            78..191
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            192..285
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            286..388
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            389..502
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             397..1644
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /note="zona pellucida-like domain-containing protein 1; ZP
                     domain-containing protein 1; cupulin"
                     /codon_start=1
                     /product="zona pellucida-like domain-containing protein 1
                     precursor"
                     /protein_id="NP_001404801.1"
                     /db_xref="GeneID:239852"
                     /db_xref="MGI:MGI:2443415"
                     /translation="MERVWLLFLLAIRVSPGSAQFNSYNCDANLHSRFPAERDISVYC
                     GVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLE
                     GCGNNLVVSTIPGVGASGNATTVQIGNISGYIDTPDPPAVISYLPGLLYKFSCSYPLE
                     YLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAA
                     VQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSF
                     EVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSG
                     NAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVLCFSLLLCS
                     LALLHRKGSTSLVLNGVRNPVFE"
     exon            503..723
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            724..905
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            906..978
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1076
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1157
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1329
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1330..1438
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1439..1468
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..2826
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1877..1882
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1907
                     /gene="Zpld1"
                     /gene_synonym="9430016A21Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggctgcttt tgagtcccag ctgaaccacc ccagcgcatt gctgtatgag ctaacaatgg
       61 gctgttaaca cagatttgta ccctgccaac tgagccatct agccagtcca aggaagtaga
      121 gtttcctaag cttggaacag tactagagaa tgtgaaaatg gcatgaaaaa gtttaacacc
      181 cttttcctca gacctgcagg ctttccctca tgaagctgac caaggctctc ttcacacata
      241 ccacacaaga ctcctgtaca gtgtaaaatg gaagatcaaa agcaggttgg aatcttttct
      301 gaaaaagttt ggtaggcatt tgaacactgt cacatgcagt gaaccaggca catggaggac
      361 agctgactct acagaaccag ggacttgggt tttgccatgg aacgagtatg gttgctgttc
      421 cttctagcga ttagagtgag tccagggtct gctcagttca acagttacaa ctgtgatgcc
      481 aacctccaca gcagatttcc tgcggaaaga gacatcagtg tctactgtgg agtgcaggcc
      541 attacgatga agattaattt ttgcacggtc cttttctcgg gatattcaga aacagatctg
      601 gcactgaatg gaagacatgg ggattcccac tgcaggggct tcatcaataa caacaccttt
      661 ccagcagtgg tcattttcat cattaatctc agcaccttgg agggctgtgg aaacaattta
      721 gtggtgtcca caattcctgg tgttggtgct tctggaaatg ctaccacagt acagatagga
      781 aatatttctg gatatattga tactccggac cctccagcag ttatcagcta tcttcctggg
      841 cttctttaca aatttagttg tagttatccg ttggaatacc tggttaataa cacccagctt
      901 gcttcgtcct cagctgctat ttctgtgaga gagaacaatg ggacatttgt cagtactttg
      961 aacttgctcc tttataacga ttcaacctac agggagcaat taattatccc gagtatagga
     1021 ttacccttga aaaccaaagt gtttgcagct gtgcaagcta ctaatctgga tggcagatgg
     1081 aatgttttaa tggattattg ctacacaacc ccatctggga atccaaatga tgatactcgg
     1141 tatgatctct tccttagctg tgacaaagat cctcagacca ctgtcatcga aaatggcaga
     1201 agccagcgag gccggttttc atttgaagtc ttccgttttg tgaaacacaa gaatcaaaag
     1261 atgtccactg tgttcctgca ctgcctcacg aaactctgca gagctgatga ctgtcctctt
     1321 ctcatgccaa tttgtggcaa cagaaaaagg agagatgctc agagctggac aacgtgggcc
     1381 ccgcagagca cttctggaaa tgcggtcctg tctgcaggac ccatcatcac ccggagcgat
     1441 gagactccaa ccaacaattc acagcttggt tcgctgagtg tgcctccctt tcagctgaat
     1501 gccgtcacca gctctctgat atcaggaatg gtcattctgg gagtcctgtg tttctctctc
     1561 ctcttgtgtt cactggccct tctacaccga aagggatcta ccagcttggt attgaatggt
     1621 gtaagaaatc ctgtctttga gtgacagtga ctggtcctgc tccagaagga gggtgtcact
     1681 gaccattctg tgtgactgtg gtcagcagtc catctgagtt caatgacagc cacccttgat
     1741 attttttagg ttaggttgat atcttgttgt agctcatgag tgttaaccta gggaaagact
     1801 tttgatagta ttgctactgc cacctatgta agtggccaac cccactttct tatcatcaaa
     1861 gggcacattg acagtaaata aaaatattga ggacttagac cttaaaaggt cagtcatttt
     1921 tcacttcatt tgtaatttct gttgatggtt ggtattaggg gtcaatctag ctatagagga
     1981 aaaaaaaaag aatttgttcc atttttctgt aagcagcaaa gcccaatgca atggttttaa
     2041 attagtgtgt cttgtccaaa aatgaaagtt acctttttat tttaaattcc aggtaattcc
     2101 agcttaaggc tacattttaa agggacattt gtgagttacc tactatttct actgacctac
     2161 tgtgtcatgg gttgattttt aatcctgatg acatttgttt caaaaggaaa caccaaaaaa
     2221 actacaaata tgcttggaaa atctattcac ataacaaata gttaaagtgg tttttaatgt
     2281 tcaaaggatg cattgtgtgt taggaaatta ttcctttggc tagcaatggc tgtgaagctt
     2341 catcctggta catatggggc catcagcaca gggtaactca cctgccagtt aaacactcag
     2401 cttccatgta gtcaagggca ctgtgcgaag ggtgttgcta attcacaagt gattacgtga
     2461 gcagcagaca ttgtcagcac catataagca tgatgctccc attcgggtcc cccagcaggc
     2521 cagaattctt tttatcctag aacaaagagg aaatacagag taagtgttgt ttgtagaaca
     2581 ttttagaagc caacatgaaa aagatgttcc tttgttcaag actttttatg agaggtaggg
     2641 aaatgaatga tccaaagggg ctttctttat aagccatcac tttttttaga tgctataatc
     2701 actacacaat gaacagtagc ttcacctagt actaaactct gagagcattt aatgccttaa
     2761 cagctttgcc aaaaaaaaaa taatgtttaa accaattttt aaacaagtca cgttcaacac
     2821 aaaagc
//
