LOCUS       NM_009580               1925 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zona pellucida glycoprotein 1 (Zp1), mRNA.
ACCESSION   NM_009580 XM_981692 XM_984406 XM_986504
VERSION     NM_009580.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1925)
  AUTHORS   He,Y., Chen,Q., Dai,J., Cui,Y., Zhang,C., Wen,X., Li,J., Xiao,Y.,
            Peng,X., Liu,M., Shen,B., Sha,J., Hu,Z., Li,J. and Shu,W.
  TITLE     Single-cell RNA-Seq reveals a highly coordinated transcriptional
            program in mouse germ cells during primordial follicle formation
  JOURNAL   Aging Cell 20 (7), e13424 (2021)
   PUBMED   34174788
REFERENCE   3  (bases 1 to 1925)
  AUTHORS   Kato,Y., Iwamori,T., Ninomiya,Y., Kohda,T., Miyashita,J., Sato,M.
            and Saga,Y.
  TITLE     ELAVL2-directed RNA regulatory network drives the formation of
            quiescent primordial follicles
  JOURNAL   EMBO Rep 20 (12), e48251 (2019)
   PUBMED   31657143
REFERENCE   4  (bases 1 to 1925)
  AUTHORS   Wang,Y., Lv,C., Huang,H.L., Zeng,M.H., Yi,D.J., Tan,H.J.,
            Peng,T.L., Yu,W.X., Deng,H.W. and Xiao,H.M.
  TITLE     Influence of mouse defective zona pellucida in folliculogenesis on
            apoptosis of granulosa cells and developmental competence of
            oocytesdagger
  JOURNAL   Biol Reprod 101 (2), 457-465 (2019)
   PUBMED   31162612
  REMARK    GeneRIF: Influence of mouse defective zona pellucida in
            folliculogenesis on apoptosis of granulosa cells and developmental
            competence of oocytesdagger.
REFERENCE   5  (bases 1 to 1925)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1925)
  AUTHORS   Rowe,L.B., Janaswami,P.M., Barter,M.E. and Birkenmeier,E.H.
  TITLE     Genetic mapping of 18S ribosomal RNA-related loci to mouse
            chromosomes 5, 6, 9, 12, 17, 18, 19, and X
  JOURNAL   Mamm Genome 7 (12), 886-889 (1996)
   PUBMED   8995758
REFERENCE   7  (bases 1 to 1925)
  AUTHORS   Epifano,O., Liang,L.F. and Dean,J.
  TITLE     Mouse Zp1 encodes a zona pellucida protein homologous to egg
            envelope proteins in mammals and fish
  JOURNAL   J Biol Chem 270 (45), 27254-27258 (1995)
   PUBMED   7592984
REFERENCE   8  (bases 1 to 1925)
  AUTHORS   Epifano,O., Liang,L.F., Familari,M., Moos,M.C. Jr. and Dean,J.
  TITLE     Coordinate expression of the three zona pellucida genes during
            mouse oogenesis
  JOURNAL   Development 121 (7), 1947-1956 (1995)
   PUBMED   7635043
REFERENCE   9  (bases 1 to 1925)
  AUTHORS   Tong,Z.B., Nelson,L.M. and Dean,J.
  TITLE     Inhibition of zona pellucida gene expression by antisense
            oligonucleotides injected into mouse oocytes
  JOURNAL   J Biol Chem 270 (2), 849-853 (1995)
   PUBMED   7822321
REFERENCE   10 (bases 1 to 1925)
  AUTHORS   Harris,J.D., Hibler,D.W., Fontenot,G.K., Hsu,K.T., Yurewicz,E.C.
            and Sacco,A.G.
  TITLE     Cloning and characterization of zona pellucida genes and cDNAs from
            a variety of mammalian species: the ZPA, ZPB and ZPC gene families
  JOURNAL   DNA Seq 4 (6), 361-393 (1994)
   PUBMED   7841460
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC125613.1.
            
            On or before Jan 29, 2007 this sequence version replaced
            XM_986504.1, XM_981692.1, XM_984406.1, NM_009580.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC125613.1, BC100347.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 7.36 cM"
     gene            1..1925
                     /gene="Zp1"
                     /note="zona pellucida glycoprotein 1"
                     /db_xref="GeneID:22786"
                     /db_xref="MGI:MGI:103073"
     exon            1..198
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..1898
                     /gene="Zp1"
                     /note="zona pellucida sperm-binding protein 1; zp-1"
                     /codon_start=1
                     /product="zona pellucida sperm-binding protein 1
                     precursor"
                     /protein_id="NP_033606.2"
                     /db_xref="CCDS:CCDS37918.1"
                     /db_xref="GeneID:22786"
                     /db_xref="MGI:MGI:103073"
                     /translation="MAWGCFVVLLLLAAAPLRLGQRLHLEPGFEYSYDCGVRGMQLLV
                     FPRPNQTVQFKVLDEFGNRFEVNNCSICYHWVTSEAQEHTVFSADYKGCHVLEKDGRF
                     HLRVFIQAVLPNGRVDIAQDVTLICPKPDHTVTPDPYLAPPTTPEPFTPHAFALHPIP
                     DHTLAGSGHTGLTTLYPEQSFIHPTPAPPSLGPGPAGSTVPHSQWGTLEPWELTELDS
                     VGTHLPQERCQVASGHIPCMVNGSSKETCQQAGCCYDSTKEEPCYYGNTVTLQCFKSG
                     YFTLVMSQETALTHGVLLDNVHLAYAPNGCPPTQKTSAFVVFHVPLTLCGTAIQVVGE
                     QLIYENQLVSDIDVQKGPQGSITRDSAFRLHVRCIFNASDFLPIQASIFSPQPPAPVT
                     QSGPLRLELRIATDKTFSSYYQGSDYPLVRLLREPVYVEVRLLQRTDPSLVLVLHQCW
                     ATPTTSPFEQPQWPILSDGCPFKGDNYRTQVVAADREALPFWSHYQRFTITTFMLLDS
                     SSQNALRGQVYFFCSASACHPLGSDTCSTTCDSGIARRRRSSGHHNITLRALDIVSSP
                     GAVGFEDAAKLEPSGSSRNSSSRMLLLLLAITLALAAGIFVGLIWAWAQKLWEGIRY"
     exon            199..320
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            321..684
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..828
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            829..1016
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1114
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1242
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1432
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1577
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1659
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1767
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1925
                     /gene="Zp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgctgaca gacagggacc tccatcatgg cctggggttg ttttgtggtc ctgcttctgc
       61 tggcggcagc tcccctgaga ttgggtcagc gcctgcatct cgagcctggc tttgaataca
      121 gctatgactg tggggtacgg ggcatgcagc tgctggtgtt ccctaggcca aaccagactg
      181 tccaattcaa ggtgctggat gaatttggga accggtttga ggtgaataac tgctctatct
      241 gctaccactg ggtgaccagt gaggcccagg agcacacagt attctcagct gattacaaag
      301 gctgccacgt tctagagaag gatgggcggt tccacctgag ggtgttcata caagccgtcc
      361 tacccaatgg ccgtgtggat atagcacaag atgtcacact gatctgtccc aaaccagacc
      421 acaccgtgac tccggacccc tacctggctc cacccaccac acctgagcct tttacacctc
      481 atgcttttgc ccttcacccc atccctgacc acaccttggc tgggtctggc cacactggtc
      541 tcactacgtt gtacccagaa cagagcttca tccatccaac tcctgctccg ccatccctag
      601 gacctggacc tgctggatcc actgtacctc actcccaatg gggcacgctg gagccctggg
      661 aattgactga gctggattct gtaggtaccc atctgcccca ggagcggtgc caggtagcct
      721 ccgggcacat cccatgcatg gtaaatggaa gttccaagga aacctgtcag caggctggct
      781 gctgctatga cagtaccaaa gaagagccct gttactatgg caacacagtc actctccagt
      841 gtttcaaaag tggctacttt accttggtca tgtcacaaga aacagccttg acacatggag
      901 tcctgctaga caatgtccac ctggcctatg cccccaacgg atgcccccct acccagaaga
      961 caagtgcttt tgtggtcttc catgtccctc tcaccctctg tggaacagca atccaggtgg
     1021 tcggcgaaca actcatctat gagaaccagc tggtgtctga cattgatgtc caaaaggggc
     1081 cacagggttc catcactcgg gacagtgcct tccggcttca tgttcgctgc atcttcaatg
     1141 ctagcgattt cctgcccatc caggcatcta tcttctcacc ccaaccacct gcccctgtga
     1201 ctcaatctgg acccctgagg ctggagctga ggattgccac ggataagact ttcagctcct
     1261 actatcaggg gagtgactat ccccttgtga gactgctccg ggaaccagtc tatgtagagg
     1321 tccgactcct gcagagaact gatcccagtc tggttctggt gctacaccag tgctgggcca
     1381 cgcccaccac cagccccttt gagcagcccc aatggcctat tctgtcagat gggtgtcctt
     1441 tcaagggtga caactacaga acacaagtag tggccgcaga cagggaggcg cttcccttct
     1501 ggtcccacta tcagcgcttc accatcacca ccttcatgct ccttgactcc agctcccaga
     1561 atgcccttag gggacaggtc tatttcttct gtagtgcctc tgcctgccac cctctggggt
     1621 ctgatacatg ctctactacg tgtgactctg ggatagcaag gcgtcgacga tcctctggtc
     1681 accacaacat cactctccgg gccctggata ttgtaagctc tccaggggca gtgggctttg
     1741 aggatgctgc taaacttgag ccctcaggtt ccagcaggaa ctccagctca agaatgctgc
     1801 tcctgctgct ggccatcacc ctagccctgg cggccgggat ctttgtgggt ctgatctggg
     1861 cctgggccca gaagctctgg gaaggcatca gatattaaat ggactcaata aaccattgtt
     1921 tgaaa
//
