LOCUS       NM_001081094            2813 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, HIT type 6 (Znhit6), transcript variant
            1, mRNA.
ACCESSION   NM_001081094 XM_131228
VERSION     NM_001081094.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2813)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2813)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC136729.7.
            
            On Feb 6, 2007 this sequence version replaced XM_131228.7.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK148729.1, BC147498.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-789               AC136729.7         149005-149793       c
            790-855             AC136729.7         147834-147899       c
            856-962             AC136729.7         147643-147749       c
            963-1048            AC136729.7         147471-147556       c
            1049-1152           AC136729.7         143369-143472       c
            1153-1221           AC136729.7         133117-133185       c
            1222-1302           AC136729.7         131321-131401       c
            1303-1380           AC136729.7         129800-129877       c
            1381-1502           AC136729.7         125422-125543       c
            1503-2813           AC136729.7         120756-122066       c
FEATURES             Location/Qualifiers
     source          1..2813
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 69.89 cM"
     gene            1..2813
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="zinc finger, HIT type 6"
                     /db_xref="GeneID:229937"
                     /db_xref="MGI:MGI:1916996"
     exon            1..789
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             161..1543
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="isoform 1 is encoded by transcript variant 1; box
                     C/D snoRNA protein 1; zinc finger HIT domain-containing
                     protein 6"
                     /codon_start=1
                     /product="box C/D snoRNA protein 1 isoform 1"
                     /protein_id="NP_001074563.1"
                     /db_xref="CCDS:CCDS38662.1"
                     /db_xref="GeneID:229937"
                     /db_xref="MGI:MGI:1916996"
                     /translation="MESAAEKEGTPGGGSQRVAEGARPRPAAGGEGARDLDGSPEAGD
                     GEERNGLAGTKTTEDAEEIKMDLAVVKQEVVDWSDLDSGVADSQWVKQEVEGGPEVKD
                     EKGVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEVKEEDLTIKQELFVG
                     QNVKEEQVMDAAPIKEEGSLKSEAMEDAKVKEEPQMNPRVGSKRKLALSRCETCGTEE
                     AKYRCPRCMRFSCSLPCVKKHKADLTCSGVRDKTAYVSLQQFTEMNLLSDYRFLEDVA
                     RTADKVSRDTFLKRPKRKKYLFFMKNRARKQGIYLRLLPNGFSKRKENSTVFDHRKQQ
                     FCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEESDPVIRQRLKAYAQSQTGV
                     QILMRVENMQQNMIRYHELDPYKSLSDNLKDKVIIEYPTLHVVLRGSSNDKQLLQVKS
                     ESAQKLGNGN"
     exon            790..855
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            856..962
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1048
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1152
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1221
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1302
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1380
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1502
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..2813
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1654..1659
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1682
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="major polyA site"
     regulatory      2262..2267
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="hexamer: AACAAA"
     polyA_site      2274
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
     regulatory      2314..2319
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="hexamer: AATATA"
     polyA_site      2346
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
     regulatory      2365..2370
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
                     /note="hexamer: AATGAA"
     polyA_site      2370
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
     polyA_site      2391
                     /gene="Znhit6"
                     /gene_synonym="2410019A14Rik"
ORIGIN      
        1 tttacggcta gctcggcttc ccgcaggcgt gcagagcttg ccgcggctgc tttgctgcac
       61 gtgtggcgct gtcggcggtt cgtttggtaa tctctcttat tggcttggtg gtgccaccgt
      121 gaagaacgga gtggcagctt cggcctaggc tcgtgagctc atggaatctg cagctgagaa
      181 ggaagggact ccgggaggag gttcccagag ggtagcggag ggggcgcggc cgaggcctgc
      241 ggctggtggg gagggagcca gggacttaga cgggagccca gaagctggcg atggagagga
      301 gaggaacgga ctggcaggaa ctaagaccac ggaggatgcg gaggagataa agatggactt
      361 agctgtggtg aagcaggaag tagtagactg gtcggattta gacagtggtg ttgcggacag
      421 ccagtgggtg aagcaggagg tggagggcgg gcccgaggtg aaggatgaga aaggcgtgtt
      481 ggaagtgaag caggaggcgg atagtagcct ggtggtgaaa gaagaggagg tggatgagcc
      541 agaagtgaag gaagagaagg tgaaggtgaa ggaggaggtg acggactggg aagaagtgaa
      601 ggaggaggac ttgaccataa aacaggagtt gtttgttggt cagaacgtaa aggaagagca
      661 agtgatggat gcagcgccta taaaagaaga gggttccctc aagagcgaag cgatggaaga
      721 cgcgaaggtg aaggaagagc cccagatgaa cccccgagtg ggcagcaaga ggaaattggc
      781 tctgtcaagg tgtgagactt gtgggacaga agaagcgaag tacagatgtc cacgctgcat
      841 gcgcttttcc tgcagtttgc cctgtgtaaa gaaacacaaa gctgacctga cgtgcagtgg
      901 agtccgggat aagaccgctt atgtgtcgct gcagcagttt actgagatga atctcctgag
      961 tgactataga tttttggaag acgtggcaag aacggcagac aaggtttcaa gagatacttt
     1021 cttgaaaaga ccaaagcgca aaaaatatct gttctttatg aagaatcgtg cccgaaagca
     1081 aggcatttac ttgaggcttc tacccaatgg atttagcaag agaaaagaga attcaacagt
     1141 ttttgaccat aggaagcagc agttttgttg gcatgtcaag ctccagtttc ctcagagtca
     1201 agcagagtac atagaaaaaa gagtaccaga tgataaaact attaatgaaa ttctaaagcc
     1261 ttacatcgat cctgaagagt ctgaccctgt gatccgtcag agattgaaag cttacgcaca
     1321 gtcacagact ggggtccaaa ttttaatgag ggtcgaaaat atgcagcaaa atatgataag
     1381 gtatcatgaa ctggatcctt acaaaagcct ttcagacaac ttgaaggaca aagtgatcat
     1441 tgagtacccg actttgcacg tggtgttgag aggatctagt aatgacaagc agctacttca
     1501 agtgaaaagt gagtctgccc agaagcttgg caatggaaat taagcactga gaaagaaggt
     1561 ggccgttccc agagggctga gaagattgtg tgttactgga ctgctgggtg actgggtccg
     1621 tcagtgggta gtgtgttgtt tatccaaaaa gtaattaaac agcataaggt ttctcacggg
     1681 gagaaagtgc atgttactgc cttttgagct aagtgactta taaaccctct tcttccatag
     1741 gatgagctcc tggttcaccc gactgctgta gtccttgcta ggcattcagt gtgctcattt
     1801 ctataagctg aaaacctgtt ttatttgtta agttgtcacg agaccaagcc caagggtcac
     1861 ctgtgtcaac cacaacgctg gcgctctctg tggtctcagc tctctgaaga gaatgcctca
     1921 catcaaagca tctagctagg gagaagccgc tgtccaggag ttggctgtcc tctggttggg
     1981 cttatgtgct atacaaaggg ttcatgtgga gccgtgttgt tgccagggcc acagggaaga
     2041 cgggaggctc catctcacgg gatgcagatg gagccaaagg tggagtctgt gtccctgaca
     2101 cgggcaggaa ggaattgaac tgaactgtct gggggtttgg gggaagaggg agaaagtaca
     2161 cagaaggaca tgtgatccaa gtgtggggag tgagggctct cctcactgaa atcagcactt
     2221 tcctctgaag ttgaagaaaa gtgttgagct ttataaaact aaacaaagaa aaaatttatt
     2281 ctgtgctttc ctctgcttcc cggagttcac ctaaatataa ctgccagctc atttggctaa
     2341 tatgcatatt tattcccaat ttataatgaa catgtgttat gtgttgtctt agttaagact
     2401 ttatgttgtg aacagacacc atgacctagg caactcttca aaagagcatt tcattggagc
     2461 tggcttacag gttcagaggt tcagtcaatg atcacgaagg taggatcata gcagtgtcca
     2521 tatgtggtac aggagatgct gagagttgta cgtcttcatc tgaaggctgc tagcagaatg
     2581 ctgacttctg ggcattgggg atgagggtct caattgcgtt ggcattgaac atcagaagcc
     2641 cacatccaca gtgccacgcc tactccaaca gagccacacc gtctaatagt gcctcccctg
     2701 ggctgagcat gtgcaaacca tcacatgtgt cataatgaat aatcgtgtta tacttacagg
     2761 gggtgaggtt ggaatagttt gctgagagcc ctggaaggca gaggtattaa agc
//
