LOCUS       NM_001005223            1010 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus zinc finger, HIT type 3 (Znhit3), transcript variant
            1, mRNA.
ACCESSION   NM_001005223
VERSION     NM_001005223.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1010)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   3  (bases 1 to 1010)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 1010)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014350.1, AK004259.1 and AI851492.1.
            
            On Dec 23, 2017 this sequence version replaced NM_001005223.2.
            
            Transcript Variant: This variant (1) encodes the longer protein
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014350.1, BY704502.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AK014350.1         2-11
            11-993              AK004259.1         3-985
            994-1010            AI851492.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 51.34 cM"
     gene            1..1010
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /note="zinc finger, HIT type 3"
                     /db_xref="GeneID:448850"
                     /db_xref="MGI:MGI:3051596"
     exon            1..111
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..481
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     thyroid hormone receptor interactor 3; zinc finger HIT
                     domain-containing protein 3; myosin head domain containing
                     1; thyroid receptor-interacting protein 3; TR-interacting
                     protein 3"
                     /codon_start=1
                     /product="zinc finger HIT domain-containing protein 3
                     isoform 1"
                     /protein_id="NP_001005223.1"
                     /db_xref="CCDS:CCDS25189.1"
                     /db_xref="GeneID:448850"
                     /db_xref="MGI:MGI:3051596"
                     /translation="MASLNCRTAVCVVCLEKPKYRCPTCRVPYCSVPCFQKHKEQCSS
                     EARPVEKRRAGPPVRSEESKDDDSSVADFLNSDEEEDRVSLQNLKNLGESETLRSLLL
                     NPHLRQLMISLDQGDNKAKLMRACMQEPLFVEFADCCLGIVEPSQKRDS"
     exon            112..143
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /inference="alignment:Splign:2.1.0"
     exon            144..218
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /inference="alignment:Splign:2.1.0"
     exon            219..299
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /inference="alignment:Splign:2.1.0"
     exon            300..998
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      904..909
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /note="hexamer: ATTAAA"
     polyA_site      929
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /note="major polyA site"
     regulatory      978..983
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /note="hexamer: AATAAA"
     polyA_site      996
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
ORIGIN      
        1 gagcgcgggt gtcttctggg aagtcatggc gtcgctgaat tgtaggactg cggtctgtgt
       61 ggtctgtttg gagaagccga aataccgttg cccgacttgc cgcgtgccct actgttcggt
      121 cccctgtttt cagaagcaca aagagcagtg cagctctgaa gcccgacctg ttgagaagag
      181 aagagcaggg cctcctgtga ggtctgagga gagcaaagat gatgactcct ccgtagctga
      241 tttcctcaac agtgatgagg aagaagacag agtgtctctg cagaatttaa agaatctagg
      301 tgaatcggaa actttaagaa gcttgctgct gaacccacac ctgaggcagt tgatgattag
      361 cctcgatcag ggtgacaaca aagcaaagct gatgcgagcc tgtatgcagg agcccctttt
      421 cgtggagttt gcagactgct gtttaggaat cgtggaacca tcccagaaga gggattccta
      481 agactggatg tgttctctgc tcaagttacc tgctgctgct ccaagaggtg gctgttttca
      541 aggccaccat acgcagcatg cacacgtggg tcttcctcta ccacatggct cgctgcagca
      601 acttcatgaa gaggaaactt gtagccctgg agtgatggct cagcagttag gagcattgac
      661 tgcttttcca gaggacccca gttttcagca cctatttgac tacttacaac tgtaattggt
      721 tgcagaggat ctgacagtct ttactgtatg catgtgcata gccatatgta cagggaaaac
      781 tcctacatac ataaaatact taaaacaaaa acaaaaggtt ggctatttat atttagatgg
      841 ttctaaattt tatttcttgt acagttcaga gttgcatcat aaataccaag tatatccatt
      901 tgaattaaaa acatagtgta acaatttaag gtgtggttct cttgatgctg cattgttcat
      961 tgttcttggt aacattaaat aaatcagttt attaaataaa aaaaaaaaaa
//
