LOCUS       NP_001005223             151 aa            linear   ROD 27-APR-2025
DEFINITION  zinc finger HIT domain-containing protein 3 isoform 1 [Mus
            musculus].
ACCESSION   NP_001005223
VERSION     NP_001005223.1
DBSOURCE    REFSEQ: accession NM_001005223.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 151)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 151)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   3  (residues 1 to 151)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (residues 1 to 151)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014350.1, AK004259.1 and AI851492.1.
            
            Transcript Variant: This variant (1) encodes the longer protein
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014350.1, BY704502.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..151
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 51.34 cM"
     Protein         1..151
                     /product="zinc finger HIT domain-containing protein 3
                     isoform 1"
                     /note="thyroid hormone receptor interactor 3; zinc finger
                     HIT domain-containing protein 3; myosin head domain
                     containing 1; thyroid receptor-interacting protein 3;
                     TR-interacting protein 3"
                     /calculated_mol_wt=16936
     Region          9..43
                     /region_name="zf-HIT_ZNHIT2-3"
                     /note="zinc finger HIT (zf-HIT) found in zinc finger HIT
                     domain-containing protein 2 (ZNHIT2), 3 (ZNHIT3) and
                     similar proteins; cd23024"
                     /db_xref="CDD:467796"
     Site            order(11,14,22,25,30,34,38,42)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:467796"
     Region          43..81
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CQK1.1)"
     Site            76
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q9CQK1.1)"
     CDS             1..151
                     /gene="Znhit3"
                     /gene_synonym="Myohd1; TRIP-3; Trip3"
                     /coded_by="NM_001005223.3:26..481"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS25189.1"
                     /db_xref="GeneID:448850"
                     /db_xref="MGI:MGI:3051596"
ORIGIN      
        1 maslncrtav cvvclekpky rcptcrvpyc svpcfqkhke qcssearpve krragppvrs
       61 eeskdddssv adflnsdeee drvslqnlkn lgesetlrsl llnphlrqlm isldqgdnka
      121 klmracmqep lfvefadccl givepsqkrd s
//
