LOCUS       NM_001029929            2993 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, MYND-type containing 15 (Zmynd15),
            transcript variant 1, mRNA.
ACCESSION   NM_001029929
VERSION     NM_001029929.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2993)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2993)
  AUTHORS   Saita,S., Shirane,M., Ishitani,T., Shimizu,N. and Nakayama,K.I.
  TITLE     Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog
            (Shh) signaling pathway
  JOURNAL   J Biol Chem 289 (37), 25639-25654 (2014)
   PUBMED   25077969
REFERENCE   3  (bases 1 to 2993)
  AUTHORS   Yan,W., Si,Y., Slaymaker,S., Li,J., Zheng,H., Young,D.L.,
            Aslanian,A., Saunders,L., Verdin,E. and Charo,I.F.
  TITLE     Zmynd15 encodes a histone deacetylase-dependent transcriptional
            repressor essential for spermiogenesis and male fertility
  JOURNAL   J Biol Chem 285 (41), 31418-31426 (2010)
   PUBMED   20675388
  REMARK    GeneRIF: ZMYND15 represents the first transcriptional repressor
            identified to be essential for sperm production and male fertility.
REFERENCE   4  (bases 1 to 2993)
  AUTHORS   Aslanian,A.M. and Charo,I.F.
  TITLE     Targeted disruption of the scavenger receptor and chemokine CXCL16
            accelerates atherosclerosis
  JOURNAL   Circulation 114 (6), 583-590 (2006)
   PUBMED   16880330
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL596096.7, BY206104.1 and AK029988.1.
            
            On Feb 8, 2017 this sequence version replaced NM_001029929.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029988.1, BC151086.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                AL596096.7         142011-142050
            41-189              BY206104.1         214-362             c
            190-2990            AK029988.1         2-2802
            2991-2993           AL596096.7         148778-148780
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.99 cM"
     gene            1..2993
                     /gene="Zmynd15"
                     /note="zinc finger, MYND-type containing 15"
                     /db_xref="GeneID:574428"
                     /db_xref="MGI:MGI:3603821"
     exon            1..648
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            649..1237
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     CDS             667..2877
                     /gene="Zmynd15"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger MYND domain-containing protein 15"
                     /codon_start=1
                     /product="zinc finger MYND domain-containing protein 15
                     isoform 1"
                     /protein_id="NP_001025100.1"
                     /db_xref="CCDS:CCDS24949.1"
                     /db_xref="GeneID:574428"
                     /db_xref="MGI:MGI:3603821"
                     /translation="MEFVSGYRDEFLDFAALLFGWFRKFVAERGTMGTSLEGRWRQLE
                     SQIRRLPQDPALWVLHVLPNRSVGISLGQGAEPGPGPGLGASRLLGDEPPLHLRDLSP
                     YVSFVSLEDGEEGEEEEEDEEHGERPGMEKVEPQEGGEPAPPSKRFPQEAKPAPESEV
                     TQQEASREEGSREERPEDERAPEKRKGQKNAEAAPLHLSCLLLVTDEHGTILGIDLLM
                     DGAQGSVGQNPGTENLAPRAYALLCHSMACPMGSGDPRKPRQLTVGDAHLHRELESLV
                     PRLGVKLAKTPMRTWGPRPGFTFASLRARTCHVCHKHSFEVKLTPCPQCSAVLYCGEA
                     CLQADWRRCPDDVSHRFWCPRLSAFMERVGELASLPFTYTAEVTSETFNKEAFLASRG
                     LTRGYWTQLSMLIPGPGAPRYPWGSTSSLSCLLNGDPYQLLQGDGPALMPPVPLEPPR
                     SLFGSWQDYYTWRGLSLDSPMAVLLTYPLTVYYVITHLVPQSFPELNIQNKQSLKIHV
                     VEAGKEFDLVMVFWELLVLLPHVALELQFVGDSLPPESDQQHFTMQRDGPEVSLRPGS
                     GVSARFNSGTKEKGGRRDLQIRVSARPYHLLQGPKPDLVIGFNSGFGLKDTWLSSLPR
                     LQSLRVPAFFTESSEYGCVMDDQTMAVATGGGTSSPQPNPFRSPFRLRAADNCMPWYC
                     NAFIFHLVYKPPQGGTVRSAPGPAPRPPTPAAPPVPARRRRGEKKAARGPRRRR"
     exon            1238..1475
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1631
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1792
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1945
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            1946..2026
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2027..2143
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2232
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2331
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2485
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2486..2544
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2545..2705
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     exon            2706..2993
                     /gene="Zmynd15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2973..2978
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zmynd15"
                     /note="hexamer: AATAAA"
     polyA_site      2993
                     /gene="Zmynd15"
                     /note="major polyA site"
ORIGIN      
        1 aaagccccgc ctcatctccg gcttctgcgg agcttgttgg gacgaggtca cctagccgac
       61 atccagccaa ttctctaaag ctttctcttc ttcaccctga ctgatgtttt gcgaaggcgc
      121 tgatccgtgc caagctcagg aggggagggg gcgcgaggtg gtggcgcctt ctgtcccccg
      181 gcgcgcgctg tccggaaccg accgtctggt cggtaccggg gagcccgctt tgcgcccagc
      241 tcccagtcgg gggacacaca cacccctgcc ccgaaggcgg agctccagtc tccggccggc
      301 cagccgtagg gtcagccaag actatccgac aaaaccgaaa gaaaatttgg gctgtagaac
      361 cagaggaatc cgagtgagca agctgtggtt cccgaagaat gactcggttg ggttcgggga
      421 tttcagccct cttgagaagt catctgtctg tctgctggtt tgtaaagtgg gtgaccctct
      481 agatccttcc tctggctcca agatgctttc acttccctgg accgctgggt ctcagtagga
      541 tccagtcaca tggccaaggt gaagcagtca aacaagtcac cagacctgta ggaatgccca
      601 cgccctggcc tgatactgcc tgacgtcacg acggtcctcc agcacgagcc ctgagtatct
      661 aaagacatgg agtttgtgtc tggataccga gacgagttcc tcgattttgc tgctcttctc
      721 tttggctggt tccgcaagtt tgtggcagag agggggacca tggggaccag ccttgagggc
      781 cgatggcgtc aactggagtc acagataagg aggctgcctc aggatcctgc cctttgggtg
      841 ctccatgtct taccaaaccg cagtgtgggc atcagcctgg ggcaaggtgc cgagccaggt
      901 cctgggccag gcctaggggc ttcccggctc ctgggagatg agcctccact tcacctgaga
      961 gacctgagtc cttatgtcag ttttgtcagc ctagaggatg gggaagaagg ggaggaggag
     1021 gaggaagatg aggagcatgg agagaggcca ggcatggaga aggtggaacc acaggagggt
     1081 ggggagccag cccctccaag caagagattc ccccaagaag caaagcctgc tccagagtca
     1141 gaggtgaccc agcaggaggc aagccgagaa gaaggcagca gagaggagcg accagaggat
     1201 gagagggctc ctgaaaagag gaaaggacag aagaatgcag aggctgcccc cctgcacctt
     1261 tcctgccttt tgctggtgac ggacgagcat ggcaccatct tgggcattga tctgctaatg
     1321 gatggagccc aggggagtgt aggccagaac ccaggcactg agaatctggc tcctcgggcc
     1381 tatgctctcc tctgtcatag catggcctgc cctatgggct ctggggaccc ccgcaagccc
     1441 cgacagctta ccgtaggaga cgcccatctc catcgagagc tagagagcct ggtcccaagg
     1501 ctgggtgtga agttggcaaa aaccccaatg cgcacgtggg gtcctcggcc aggttttact
     1561 tttgcctccc ttcgggctcg aacctgccat gtttgtcaca agcacagctt tgaggtgaag
     1621 ttgacaccct gcccccagtg cagtgcagtc ttgtactgtg gagaggcttg tctccaggct
     1681 gattggcggc gatgcccaga tgacgtgagc caccgattct ggtgcccaag gctctcagcg
     1741 ttcatggagc gggtcggaga actggcaagt ttgcctttca cctatactgc agaagttacc
     1801 agtgaaacct ttaacaagga agctttcctg gcctcccgag gcctcactcg tggttattgg
     1861 acccagctca gcatgctgat tccagggccg ggtgccccca ggtacccctg gggcagcaca
     1921 tcatccctca gctgccttct caacggtgat ccttaccagc ttctgcaggg agacgggcct
     1981 gccttgatgc ctccggtgcc cctcgagcca cccaggagcc tctttggttc atggcaggat
     2041 tactacacgt ggcggggcct cagcctggac tcccccatgg ctgtgcttct cacctaccca
     2101 ctgacggtgt actatgtcat cacccacctg gtaccccagt ccttccctga gctcaacatc
     2161 cagaacaagc aatccctgaa gatccacgtg gtggaggctg gcaaggaatt cgatctcgtc
     2221 atggtgtttt gggagctctt ggtccttctc ccccatgtgg ccctggagct acagtttgtg
     2281 ggtgacagcc tgccacctga gagtgaccag cagcatttta ctatgcagag ggatggacct
     2341 gaggtgtctc tgcgtcctgg ttctggagta tcagcacggt tcaactctgg gactaaggag
     2401 aagggaggtc gaagggacct gcaaatcagg gtgtctgcca ggccctatca cctgctccag
     2461 ggacccaagc ctgacctggt tattggattt aactccggct ttggtctcaa agatacatgg
     2521 ctgagctctc taccccggtt acagtctctc cgagtgccag cattcttcac tgagagcagt
     2581 gagtacggct gtgtgatgga cgatcagact atggcggtgg ccaccggagg gggcaccagc
     2641 tcgccacagc ccaacccctt ccgctcccca ttccgcctta gagcagctga caactgtatg
     2701 ccctggtact gcaacgcctt catcttccat ttggtctaca agcctcccca aggcggcaca
     2761 gtccgctcgg ctcccggccc tgcacctaga cccccaactc ccgctgcacc tcctgtcccg
     2821 gctcgaaggc gccgaggaga aaagaaagct gcacgcgggc cccgccggcg cagatgagag
     2881 cggacttggc agccgtccat tcccaagcat gcgccctaaa ggaaaacatt ccaaggccca
     2941 gggaagactg attgtcggaa cacaaaaggt taaataaaat tacttgtttg aaa
//
