LOCUS       NM_001199141            4136 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger, MYND domain containing 11 (Zmynd11),
            transcript variant 3, mRNA.
ACCESSION   NM_001199141
VERSION     NM_001199141.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4136)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4136)
  AUTHORS   Parker,C.C., Gopalakrishnan,S., Carbonetto,P., Gonzales,N.M.,
            Leung,E., Park,Y.J., Aryee,E., Davis,J., Blizard,D.A.,
            Ackert-Bicknell,C.L., Lionikas,A., Pritchard,J.K. and Palmer,A.A.
  TITLE     Genome-wide association study of behavioral, physiological and gene
            expression traits in outbred CFW mice
  JOURNAL   Nat Genet 48 (8), 919-926 (2016)
   PUBMED   27376237
REFERENCE   3  (bases 1 to 4136)
  AUTHORS   Galazo,M.J., Emsley,J.G. and Macklis,J.D.
  TITLE     Corticothalamic Projection Neuron Development beyond Subtype
            Specification: Fog2 and Intersectional Controls Regulate Intraclass
            Neuronal Diversity
  JOURNAL   Neuron 91 (1), 90-106 (2016)
   PUBMED   27321927
REFERENCE   4  (bases 1 to 4136)
  AUTHORS   Harter,M.R., Liu,C.D., Shen,C.L., Gonzalez-Hurtado,E., Zhang,Z.M.,
            Xu,M., Martinez,E., Peng,C.W. and Song,J.
  TITLE     BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2
  JOURNAL   PLoS Pathog 12 (2), e1005414 (2016)
   PUBMED   26845565
  REMARK    GeneRIF: This study identifies the BS69 C-terminal domains as an
            inhibitor of EBNA2.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4136)
  AUTHORS   Wen,H., Li,Y., Xi,Y., Jiang,S., Stratton,S., Peng,D., Tanaka,K.,
            Ren,Y., Xia,Z., Wu,J., Li,B., Barton,M.C., Li,W., Li,H. and Shi,X.
  TITLE     ZMYND11 links histone H3.3K36me3 to transcription elongation and
            tumour suppression
  JOURNAL   Nature 508 (7495), 263-268 (2014)
   PUBMED   24590075
REFERENCE   6  (bases 1 to 4136)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   7  (bases 1 to 4136)
  AUTHORS   Yu,B., Shao,Y., Zhang,C., Chen,Y., Zhong,Q., Zhang,J., Yang,H.,
            Zhang,W. and Wan,J.
  TITLE     BS69 undergoes SUMO modification and plays an inhibitory role in
            muscle and neuronal differentiation
  JOURNAL   Exp Cell Res 315 (20), 3543-3553 (2009)
   PUBMED   19766626
REFERENCE   8  (bases 1 to 4136)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   9  (bases 1 to 4136)
  AUTHORS   Velasco,G., Grkovic,S. and Ansieau,S.
  TITLE     New insights into BS69 functions
  JOURNAL   J Biol Chem 281 (24), 16546-16550 (2006)
   PUBMED   16565076
  REMARK    GeneRIF: BS69 has roles in gene repression and chromatin remodeling
REFERENCE   10 (bases 1 to 4136)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY131252.1, CB526775.1, AK145892.1, BC058999.1 and AW488181.1.
            
            On Nov 29, 2016 this sequence version replaced NM_001199141.1.
            
            Transcript Variant: This variant (3) differs in the 5' UTR and uses
            an alternate in-frame splice site in the 3' coding region, compared
            to variant 8. The encoded isoform (gamma) is shorter than isoform
            beta. Variants 3, 4 and 5 all encode isoform gamma.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022945.1, SRR13861890.198145.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 BY131252.1         1-7
            8-378               CB526775.1         1-371
            379-2714            AK145892.1         4-2339
            2715-3848           BC058999.1         2674-3807
            3849-4136           AW488181.1         1-288               c
FEATURES             Location/Qualifiers
     source          1..4136
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 3.72 cM"
     gene            1..4136
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /note="zinc finger, MYND domain containing 11"
                     /db_xref="GeneID:66505"
                     /db_xref="MGI:MGI:1913755"
     exon            1..267
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            268..402
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     CDS             287..2095
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /note="isoform gamma is encoded by transcript variant 3;
                     zinc finger MYND domain-containing protein 11"
                     /codon_start=1
                     /product="zinc finger MYND domain-containing protein 11
                     isoform gamma"
                     /protein_id="NP_001186070.1"
                     /db_xref="CCDS:CCDS56870.1"
                     /db_xref="GeneID:66505"
                     /db_xref="MGI:MGI:1913755"
                     /translation="MARLTKRRQADTKAIQHLWAAIEIIRNQKQIANIDRITKYMSRV
                     HGMHPKETTRQLSLAVKDGLIVETLTVGCKGSKAGIEQEGYWLPGDEIDWETETHDWY
                     CFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSHWQCPVCRSIKKKHSNKQEMGT
                     YLRFIVSRMKERAIDLNKKGKDSKHPMYRRLVHSAVDVPTIQEKVNEGKYRSYEEFKA
                     DAQLLLHNTVIFYGADSEQADIARMLYKDTCHELDELQLCKNCFYLSNARPDNWFCYP
                     CIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFGHHHQRAWIPSENIQDITVNVHR
                     LHVKRSMGWKKACDELELHQRFLREGRFWKSKNEDRGEEEAESSISSTSNEQLKVTQE
                     PRAKKGRRNQSVEPKKEEPEPETEAVSSSQEIPTMPQPIERVSVSTQTKKLSASSPRM
                     LHRSTQTTSDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEE
                     KRQAVNKAVASLQGDMDRKGKQLKEKCKEEFVEEIKKLAAQHKQLISQTKKKQWCYNC
                     EEEAMYHCCWNTSYCSIKCQQEHWHAEHKRTCRRKR"
     exon            403..562
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            563..724
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            725..802
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            803..895
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            896..983
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1039
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1117
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1236
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1444
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1513
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1786
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1972
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     exon            1973..4121
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4098..4103
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /note="hexamer: AATAAA"
     polyA_site      4121
                     /gene="Zmynd11"
                     /gene_synonym="2210402G22Rik; BS69"
                     /note="major polyA site"
ORIGIN      
        1 agtagtacac gggcgagtgc ttgtccaaca cggagccatt aggagccaag caaagtgccg
       61 agcgggtcca caccgcaagc tgcaacgcag cccaccgggc ttggccggat cctaacaatg
      121 ctaccctcgt gtctcggtgc tcgcctccag cgcgcctgca cgtacgtagc tcgcacgtgt
      181 gtgttgacat ggagttcgtg tgtggacccc cttagaatat gctgaaaccg atttctcagc
      241 gaggcgccgg agacaggtcg agggaagcta aagaagtaaa caggtcatgg cacgtttaac
      301 aaaaagacga caggcggata caaaagctat ccagcatctt tgggcagcca ttgaaattat
      361 cagaaatcag aagcagattg ccaacattga tcgtattaca aagtatatgt cccgagtcca
      421 cggtatgcat cccaaagaga ccacccgcca gctgagctta gctgtgaaag atggtcttat
      481 tgtcgaaact ctaacagtgg gctgcaaagg ttcaaaagct ggtattgaac aggaaggata
      541 ttggttacca ggagatgaga ttgactggga aacagaaact catgactggt attgttttga
      601 atgccatttg cctggagagg tgttgatatg tgacctgtgt tttcgtgtgt atcattccaa
      661 gtgtttgtct gatgagttca ggcttagaga cagcagtagt cactggcagt gcccagtttg
      721 caggagcatt aagaagaagc actctaacaa gcaggaaatg ggcacctact tgaggttcat
      781 cgtctcccga atgaaggagc gggctataga ccttaataag aaaggaaagg acagtaagca
      841 tcctatgtac cggaggctgg tccactcagc tgttgacgtc cctaccatac aagagaaggt
      901 gaatgagggg aagtaccgga gttacgagga gttcaaggct gacgcacagc tgcttctcca
      961 caacacagtg atcttctatg gagcagacag tgagcaggcg gacattgcac ggatgttata
     1021 taaagacacg tgtcacgagc tggacgagct gcagctttgc aagaactgct tctatctgtc
     1081 aaacgcacgg cccgacaact ggttctgcta cccttgcata cctaatcatg agctggtttg
     1141 ggctaaaatg aaaggttttg ggttttggcc agccaaagtc atgcagaaag aagacaatca
     1201 agtggatgtt cgcttctttg gccatcacca ccagagagcc tggattcctt ctgaaaacat
     1261 ccaggatatc acggtcaatg ttcaccgact gcacgtgaag cgcagcatgg gctggaagaa
     1321 ggcctgtgac gagctggaac tgcatcagcg cttcctccgt gaaggaaggt tctggaagtc
     1381 taagaatgag gaccgaggtg aggaagaggc agaatccagt atctcctcca ccagtaacga
     1441 gcagctgaag gtcactcaag agccaagagc aaagaaagga cgacgtaatc agagtgtgga
     1501 gcccaaaaag gaagaacccg agccagaaac ggaagcagtg agttccagcc aggaaatccc
     1561 cacaatgcct cagccaattg agagggtgtc agtgtcaacc cagaccaaga agttaagtgc
     1621 ctcttcccca cgaatgctgc atcgaagcac tcagacgacg agcgacggcg tctgtcagag
     1681 catgtgccac gacaagtaca ccaaaatttt taatgacttt aaagacagga tgaagtcgga
     1741 ccacaagcgg gaaacagaga gagtggtccg tgaagcgctg gaaaagttgc gttctgaaat
     1801 ggaagaagaa aaaagacagg ccgtgaacaa agctgtggcc agcctgcagg gcgacatgga
     1861 cagaaagggt aagcagctga aggagaagtg caaggaagag tttgtagagg agatcaagaa
     1921 gctagcggcg cagcacaagc agctcatttc ccagaccaag aagaagcagt ggtgctacaa
     1981 ctgtgaggag gaggccatgt accactgctg ctggaacacg tcctactgct ccatcaagtg
     2041 ccagcaggag cactggcacg cagagcacaa gcgcacctgc cgccggaaga gatgagcctg
     2101 ccgccaccct cacacgcagc ggtttttgtt cccaagaagc caaaattgtt tagaatttgc
     2161 ttcccatttt gcaccagcct ttaaacactt ttcgtggtga aattttgcac agtagtttaa
     2221 atcttttgtt aatgctcctc cggcattttt cgggggctga agtaacatca atggagggta
     2281 ctactctaaa taaatctaat tgcggatttg ttgcattttc agcaaatttt aaaacatttt
     2341 taggttttac agaaatttta acctttaaac aacaaatctt aaaaaaacaa cgacaggtga
     2401 ataagagaga gtctaacaga gacagaacgg agctgaatgt aagagcggat gcttcagaac
     2461 agactacctg gccgtgacct tgctgagctg gttttgggca gcttgcttac tgcctacagg
     2521 ccttgcctgg ggctgtgctg gcggcatgtg attgaatata gggaacaggg ttcacacagc
     2581 agggctagcc ctgcggattt tttcttaaat atttcccaat tgtgttttca ttatttcttt
     2641 tcaatatata acttttataa caaattatta gctttgatct tgtagtttaa aattgcaggg
     2701 aaactggggt aatcttttac tgagctggat cttagagaaa aatgaatatt taaattttaa
     2761 agtttgcaca tttcatcttt gtcctgacat gagtgcttgt aacaaaatca gcagcaaaaa
     2821 caaaaatcaa aagccaaaaa ctacctgtac tcagaacacg gaattacagc tgaggcatac
     2881 gagtttataa ctgagtcccc tcccaccttc cctccccagt gccaccctaa cccaccctgt
     2941 gtctcctact cagagggaga gagcacttgc gtgtcacaca ctgctactaa caaatccctg
     3001 actgtacaca gtgagaatgc atgctccgtt ccttgtatta aagatgccgt gatttgtaca
     3061 aagtccgtat tctgcggggt gtctgcttaa gcagcgttac tggtaggaat ggatcgatag
     3121 ttgaataaca ttttttatac atagatatat aaaagacaac caggaaaatt aaatttcttt
     3181 aaaactatct caccaattgt ttttttttct cctccaagac tcatcacaga ccgaaccaaa
     3241 ttcctacttt atcctttagt tattttttga ggttagagaa ataatttgta aatatttatt
     3301 tagacctttg atatttatta aagcaattac tcaaaacaga agtgaaagag tcgggagaaa
     3361 agcctttaag acagttttcc ccggttcatc agggtcactc taaagatgaa aggaaggagc
     3421 cgtctgtgag gcctcctcca cgcagtgccg gtgctactgc agacggcgta actactgcca
     3481 cacacgcgca cggggcgagc tcttttgtaa aaccaaccgt agcccaggag ctccctcggg
     3541 ttatacagga actgcaatag cttacaggca ccaccgcccc ctcctcgctg ccgtgtacca
     3601 tcactgctgc tgcgctgccc gaacaaggac acttgacggt ctttgattgt tttcagacgt
     3661 tgatccaccc ctgtgagagc aagttattgt gggaatattt ttggtgtaaa atcattccag
     3721 agtatgtact atttacctga tagctgcatg aacgtgaggt ccctgttact ttggcttctt
     3781 gtctctgtcg acacggctgc acatttccaa gtaactacag tgtgaaaact gtgtgtttta
     3841 aaaaaaaaca acaaaaaaaa aattaaaaaa agagattgtg gcctggtttt gtaaaagttt
     3901 taggtaaaat tacaattgat tgttttagga ctcattaaat ttttctgcaa tcctaaagct
     3961 ctatcaaggt gttgagtgtc ccgctctgca cactgtaagt accattgtgg ctgtccagtt
     4021 ctatgatgcc ctctggcatt ttgtaagctg ctctgactag caatatatag atttcattta
     4081 ctgtgttaac attggttaat aaatgtattt aaaaaaccca aaaaaaaaaa aaaaaa
//
