LOCUS       NP_444483                440 aa            linear   ROD 02-MAY-2024
DEFINITION  zinc finger MYND domain-containing protein 10 isoform 1 [Mus
            musculus].
ACCESSION   NP_444483 XP_981515
VERSION     NP_444483.2
DBSOURCE    REFSEQ: accession NM_053253.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 440)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 440)
  AUTHORS   Mali,G.R., Yeyati,P.L., Mizuno,S., Dodd,D.O., Tennant,P.A.,
            Keighren,M.A., Zur Lage,P., Shoemark,A., Garcia-Munoz,A.,
            Shimada,A., Takeda,H., Edlich,F., Takahashi,S., von Kreigsheim,A.,
            Jarman,A.P. and Mill,P.
  TITLE     ZMYND10 functions in a chaperone relay during axonemal dynein
            assembly
  JOURNAL   Elife 7, e34389 (2018)
   PUBMED   29916806
  REMARK    GeneRIF: ZMYND10 is a novel co-chaperone that confers specificity
            for the FKBP8-HSP90 chaperone complex towards axonemal dynein
            clients required for cilia motility.
            Publication Status: Online-Only
REFERENCE   3  (residues 1 to 440)
  AUTHORS   Cho,K.J., Noh,S.H., Han,S.M., Choi,W.I., Kim,H.Y., Yu,S., Lee,J.S.,
            Rim,J.H., Lee,M.G., Hildebrandt,F. and Gee,H.Y.
  TITLE     ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic
            pre-assembly of dynein arms
  JOURNAL   PLoS Genet 14 (3), e1007316 (2018)
   PUBMED   29601588
  REMARK    GeneRIF: results demonstrated that ZMYND10 regulated the early
            stage of DA cytoplasmic pre-assembly by stabilizing DNAI1
            Publication Status: Online-Only
REFERENCE   4  (residues 1 to 440)
  AUTHORS   Shi,B., Xue,J., Zhou,J., Kasowitz,S.D., Zhang,Y., Liang,G.,
            Guan,Y., Shi,Q., Liu,M., Sha,J., Huang,X. and Wang,P.J.
  TITLE     MORC2B is essential for meiotic progression and fertility
  JOURNAL   PLoS Genet 14 (1), e1007175 (2018)
   PUBMED   29329290
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 440)
  AUTHORS   Moore,D.J., Onoufriadis,A., Shoemark,A., Simpson,M.A., zur
            Lage,P.I., de Castro,S.C., Bartoloni,L., Gallone,G., Petridi,S.,
            Woollard,W.J., Antony,D., Schmidts,M., Didonna,T.,
            Makrythanasis,P., Bevillard,J., Mongan,N.P., Djakow,J., Pals,G.,
            Lucas,J.S., Marthin,J.K., Nielsen,K.G., Santoni,F., Guipponi,M.,
            Hogg,C., Antonarakis,S.E., Emes,R.D., Chung,E.M., Greene,N.D.,
            Blouin,J.L., Jarman,A.P. and Mitchison,H.M.
  TITLE     Mutations in ZMYND10, a gene essential for proper axonemal assembly
            of inner and outer dynein arms in humans and flies, cause primary
            ciliary dyskinesia
  JOURNAL   Am J Hum Genet 93 (2), 346-356 (2013)
   PUBMED   23891471
REFERENCE   6  (residues 1 to 440)
  AUTHORS   Agathanggelou,A., Dallol,A., Zochbauer-Muller,S., Morrissey,C.,
            Honorio,S., Hesson,L., Martinsson,T., Fong,K.M., Kuo,M.J.,
            Yuen,P.W., Maher,E.R., Minna,J.D. and Latif,F.
  TITLE     Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU
            in human cancers
  JOURNAL   Oncogene 22 (10), 1580-1588 (2003)
   PUBMED   12629521
REFERENCE   7  (residues 1 to 440)
  AUTHORS   Lerman,M.I. and Minna,J.D.
  TITLE     The 630-kb lung cancer homozygous deletion region on human
            chromosome 3p21.3: identification and evaluation of the resident
            candidate tumor suppressor genes. The International Lung Cancer
            Chromosome 3p21.3 Tumor Suppressor Gene Consortium
  JOURNAL   Cancer Res 60 (21), 6116-6133 (2000)
   PUBMED   11085536
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY284492.1, BC052357.1 and AL672219.7.
            
            On or before May 4, 2006 this sequence version replaced
            XP_981515.1, NP_444483.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052357.1, AK132332.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 58.12 cM"
     Protein         1..440
                     /product="zinc finger MYND domain-containing protein 10
                     isoform 1"
                     /note="zinc finger MYND domain-containing protein 10;
                     protein BLu"
                     /calculated_mol_wt=50516
     Region          394..430
                     /region_name="zf-MYND"
                     /note="MYND finger; pfam01753"
                     /db_xref="CDD:460312"
     CDS             1..440
                     /gene="Zmynd10"
                     /gene_synonym="Blu"
                     /coded_by="NM_053253.4:154..1476"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS23493.1"
                     /db_xref="GeneID:114602"
                     /db_xref="MGI:MGI:2387863"
ORIGIN      
        1 mgdlelllpg eaevlvrglr sfqlremgse gwnkqhesle klnmqailda tisqaepiqe
       61 llinhgkipt lveeliavem wkqkvfpvlc rledfkpqnt fpiymvvhhe asiinlletv
      121 ffhkevcesa ddkvldlvdy chrklillva rkgggdlsee eqfqdstpmq elqkqaemme
      181 feislkalsv lryitdcvds lslstlnrml rthnlpcllv ellehspwsr rvggklqhfe
      241 sgrwqtvaps eqqklnkldg qvwialynll lspeararyc ltsfakgqll klqafltdtl
      301 ldqlpnladl kgflahlsla etqppkkdlv leqipeiwdr lerenkgkwq aiakhqlqhv
      361 fslsekdlrq qaqrwaetyr ldvleavape rprcgycnae askrcsrcqn vwyccrecqv
      421 khwekhgktc vlaaqgdrak
//
