LOCUS       NM_019831               5430 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus zinc finger, MYM-type 3 (Zmym3), transcript variant 1,
            mRNA.
ACCESSION   NM_019831
VERSION     NM_019831.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5430)
  AUTHORS   Shapson-Coe,A., Valeiras,B., Wall,C. and Rada,C.
  TITLE     Aicardi-Goutieres Syndrome associated mutations of RNase H2B impair
            its interaction with ZMYM3 and the CoREST histone-modifying complex
  JOURNAL   PLoS One 14 (3), e0213553 (2019)
   PUBMED   30889214
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5430)
  AUTHORS   Zhou,J., Wang,R., Zhang,J., Zhu,L., Liu,W., Lu,S., Chen,P., Li,H.,
            Yin,B., Yuan,J., Qiang,B., Shu,P. and Peng,X.
  TITLE     Conserved expression of ultra-conserved noncoding RNA in mammalian
            nervous system
  JOURNAL   Biochim Biophys Acta Gene Regul Mech 1860 (12), 1159-1168 (2017)
   PUBMED   29055695
REFERENCE   3  (bases 1 to 5430)
  AUTHORS   Hu,X., Shen,B., Liao,S., Ning,Y., Ma,L., Chen,J., Lin,X., Zhang,D.,
            Li,Z., Zheng,C., Feng,Y., Huang,X. and Han,C.
  TITLE     Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic
            metaphase with defects in spindle assembly checkpoint
  JOURNAL   Cell Death Dis 8 (6), e2910 (2017)
   PUBMED   28661483
  REMARK    GeneRIF: Zmym3 KO also resulted in up-regulated expression of
            meiotic genes in spermatogonia. These results show that ZMYM3 has
            an essential role in metaphase to anaphase transition during mouse
            spermatogenesis by regulating the expression of diverse families of
            genes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5430)
  AUTHORS   Amakawa,Y., Sakata,Y., Hoki,Y., Arata,S., Shioda,S., Fukagawa,T.,
            Sasaki,H. and Sado,T.
  TITLE     A new Xist allele driven by a constitutively active promoter is
            dominated by Xist locus environment and exhibits the
            parent-of-origin effects
  JOURNAL   Development 142 (24), 4299-4308 (2015)
   PUBMED   26511926
REFERENCE   5  (bases 1 to 5430)
  AUTHORS   Carmona-Mora,P., Widagdo,J., Tomasetig,F., Canales,C.P., Cha,Y.,
            Lee,W., Alshawaf,A., Dottori,M., Whan,R.M., Hardeman,E.C. and
            Palmer,S.J.
  TITLE     The nuclear localization pattern and interaction partners of
            GTF2IRD1 demonstrate a role in chromatin regulation
  JOURNAL   Hum Genet 134 (10), 1099-1115 (2015)
   PUBMED   26275350
REFERENCE   6  (bases 1 to 5430)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5430)
  AUTHORS   Chiba,H., Hirasawa,R., Kaneda,M., Amakawa,Y., Li,E., Sado,T. and
            Sasaki,H.
  TITLE     De novo DNA methylation independent establishment of maternal
            imprint on X chromosome in mouse oocytes
  JOURNAL   Genesis 46 (12), 768-774 (2008)
   PUBMED   18932249
REFERENCE   8  (bases 1 to 5430)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   9  (bases 1 to 5430)
  AUTHORS   Scheer,M.P., van der Maarel,S., Kubart,S., Schulz,A., Wirth,J.,
            Schweiger,S., Ropers,H. and Nothwang,H.G.
  TITLE     DXS6673E encodes a predominantly nuclear protein, and its mouse
            ortholog DXHXS6673E is alternatively spliced in a developmental-
            and tissue-specific manner
  JOURNAL   Genomics 63 (1), 123-132 (2000)
   PUBMED   10662551
REFERENCE   10 (bases 1 to 5430)
  AUTHORS   van der Maarel,S.M., Scholten,I.H., Huber,I., Philippe,C.,
            Suijkerbuijk,R.F., Gilgenkrantz,S., Kere,J., Cremers,F.P. and
            Ropers,H.H.
  TITLE     Cloning and characterization of DXS6673E, a candidate gene for
            X-linked mental retardation in Xq13.1
  JOURNAL   Hum Mol Genet 5 (7), 887-897 (1996)
   PUBMED   8817323
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL831722.8.
            
            On May 5, 2010 this sequence version replaced NM_019831.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF156605.1, BC139001.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AL831722.8         24903-24979         c
            78-757              AL831722.8         23030-23709         c
            758-801             AL831722.8         22044-22087         c
            802-874             AL831722.8         21666-21738         c
            875-1169            AL831722.8         20924-21218         c
            1170-1347           AL831722.8         20518-20695         c
            1348-1566           AL831722.8         19945-20163         c
            1567-1717           AL831722.8         19505-19655         c
            1718-1833           AL831722.8         19179-19294         c
            1834-1920           AL831722.8         18932-19018         c
            1921-2071           AL831722.8         18661-18811         c
            2072-2244           AL831722.8         18246-18418         c
            2245-2410           AL831722.8         17869-18034         c
            2411-2508           AL831722.8         17135-17232         c
            2509-2665           AL831722.8         16895-17051         c
            2666-2778           AL831722.8         16602-16714         c
            2779-2953           AL831722.8         16289-16463         c
            2954-3100           AL831722.8         15970-16116         c
            3101-3204           AL831722.8         14814-14917         c
            3205-3373           AL831722.8         14369-14537         c
            3374-3525           AL831722.8         13911-14062         c
            3526-3640           AL831722.8         13234-13348         c
            3641-3895           AL831722.8         11962-12216         c
            3896-4010           AL831722.8         10662-10776         c
            4011-5430           AL831722.8         9141-10560          c
FEATURES             Location/Qualifiers
     source          1..5430
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 44.1 cM"
     gene            1..5430
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /note="zinc finger, MYM-type 3"
                     /db_xref="GeneID:56364"
                     /db_xref="MGI:MGI:1927231"
     exon            1..77
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            78..757
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..4203
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger MYM-type protein 3; zinc finger protein 261"
                     /codon_start=1
                     /product="zinc finger MYM-type protein 3 isoform 1"
                     /protein_id="NP_062805.1"
                     /db_xref="CCDS:CCDS30315.1"
                     /db_xref="GeneID:56364"
                     /db_xref="MGI:MGI:1927231"
                     /translation="MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPSRG
                     WAPPGPSPSSGALDLLDTPSGLEKDPGGVLDGATELLGLGGLLYKAPSPPEVDHGPEG
                     TLAWDSGEQTLEPGPGCQTPEVMPPDPGAGASPPSPEGLLEPLAPDSPIILESPHIEE
                     EIPPLATRRRGSPGQEEEHTQGQPQSPNAPPSPSVGETLGDGINSSQSKPGVCTPTAH
                     PSLPGDGLTGKEIEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDP
                     NDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQ
                     LFCSSSCLTTYSKKPLGRKTCTFCKKEIWNTKDSVVVQTGPGGSFHEFCTSVCLSLYE
                     AQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKT
                     NCCDQCGAYIYARPGGLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCK
                     NFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDR
                     TVYQFCSPSCWTKFQHTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCED
                     FKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCT
                     YCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQ
                     IRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENNHTVRTP
                     DENGNLGKTPVKRATPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKAEMKSKGS
                     QTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIV
                     ETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLF
                     GTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQ
                     DLPRAMRKGQKRLMLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGETSKG
                     DELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQY
                     LLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVY
                     SPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPV
                     RQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYL
                     QPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD"
     exon            758..801
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            802..874
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            875..1169
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1347
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1348..1566
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1567..1717
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1833
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1834..1920
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2071
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2244
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2245..2410
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2508
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2665
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2666..2778
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2779..2953
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3100
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3101..3204
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3205..3373
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3374..3525
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3526..3640
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3641..3895
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            3896..4010
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     exon            4011..5430
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5412..5417
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /note="hexamer: AATAAA"
     polyA_site      5429
                     /gene="Zmym3"
                     /gene_synonym="9030216B10Rik; DXS6673El; Zfp261"
                     /note="major polyA site"
ORIGIN      
        1 cgggtagagt gggctctgga gatagggcgg gcacgggtgt gacggggcca ggctcttgag
       61 ccaggtaagg aaagcagccc atacccagcc atggacccca gtgatttccc cagtccattt
      121 gacccattga ccctgccaga gaagcccctg gctggagacc ttccagtaga catggaattt
      181 ggagaggatc tgctggaatc tcagactgcc ccaagtcgag gatgggctcc cccaggtccg
      241 tctccatcct ctggagccct ggacctgctt gatacccctt ctggcctgga gaaggaccct
      301 ggaggagttc tggatggagc cactgagcta ctggggctgg gggggctact ctataaagcc
      361 ccttctcccc cagaggtgga ccatggtcct gagggaaccc ttgcatggga ttcgggggag
      421 cagaccctag agcctggacc agggtgtcaa acccctgagg tgatgccacc tgatccaggg
      481 gctggggcta gtcccccttc acctgagggg ctactagaac ctttggctcc agattctcca
      541 ataatcctgg agtctcctca tattgaagag gagatacccc ccttagctac aaggagaagg
      601 ggctcccctg ggcaggagga ggagcatacc caagggcagc cacagagccc caatgcaccc
      661 cctagccctt cagtgggaga gactctgggg gatggcatca acagttctca gagcaaacct
      721 ggggtatgta cccctactgc acatccttcg ttgccaggag atggcctgac tgggaaggag
      781 attgagaagc cgcctgagag ggtacagaag agaagcgagc gcgttagaag agcagaacct
      841 ccaaagcctg aggttgtgga ctccactgag agcattccag tgtcagatga ggattctgat
      901 gccatggtag atgaccccaa tgatgaggac tttgtgccat tccggccccg gcgctctcct
      961 cgcatgtccc tgcgctcaag tatggcacaa agggctgggc gctcttcaat gggcaccaag
     1021 atgtcttgtg cacattgccg gacaccactg cagaaggggc agacggccta tcagcgcaag
     1081 gggttgcctc agctcttctg ttcttcatct tgtctcacta cttactccaa gaagcccttg
     1141 ggcagaaaga cctgtacctt ctgcaagaag gagatctgga acaccaagga ctcagttgtg
     1201 gtacagactg gtccaggagg ctccttccat gagttctgca catctgtctg tctctctctc
     1261 tatgaggccc agcagcagcg tccaatcccc cagtctgggg atcctgccga tgccactcgc
     1321 tgcagcatat gccagaagac tggagaggtt cttcatgagg tcagcaatgg cagcgtggta
     1381 caccgactct gcagcgattc ttgcttctcc aaattccgag ccaacaaggg actgaaaacc
     1441 aactgttgtg accagtgtgg ggcttacatc tatgccaggc ctgggggcct tggcccagag
     1501 ctcctgtttc atgatggtca acaaaagcgg ttttgcaaca caacgtgctt gggggcatac
     1561 aagaagaaaa acacacgtgt gtacccatgt gtctggtgca agaccctgtg taagaacttt
     1621 gagatgctat cacatgtgga tcgtaatggc aagaccagct tgttctgttc cctgtgctgt
     1681 accacttctt acaaagtgaa gcaggcaggg ctcactggcc ctccccgacc ctgcagcttc
     1741 tgccgccgca gcctctctga cccttgttac tacaacaaag ttgatcgcac agtctaccag
     1801 ttctgcagcc ccagctgctg gaccaagttc cagcatacta gccctgaggg gggcattcac
     1861 ctgagctgtc actactgcca tagcctcttc agtggcaagc ctgaggtctt ggagtggcag
     1921 gaccaggtct tccagttctg ctgccgtgat tgctgtgagg acttcaagcg gcttcggggt
     1981 gtggtatccc agtgtgagca ctgccggcag gaaaagctcc tgcacgagaa gcttcgattc
     2041 agtggggtag agaaaagctt ctgcagtgaa ggctgtgtac tgctgtacaa gcaagatttt
     2101 actaagaagc tgggcttatg ttgtatcacc tgtacttact gttcccaaac ctgccagcgt
     2161 ggtgtcactg agcagctgga tggcagcacc tgggacttct gcagcgagga ctgtaagacc
     2221 aagtacctgt tatggtactg caaggctgcc cggtgccatg cctgtaagcg ccaggggaag
     2281 ctgctggaaa cgatccactg gcgtgggcaa atccgtcatt tctgcaacca acagtgtctg
     2341 ctgcgtttct acagccagca gaaccaaccc aacttggata cccagagtgg gccagaaagc
     2401 ctcctgaaca gtcagtcttc tgagtccaag ccccagacac cctctcaaac caaagtggag
     2461 aacaaccaca cagtgaggac cccagacgag aatgggaatt tgggcaagac tcctgtgaag
     2521 agagcaactc caagtgtgcc cactcctcca cccccaccgc ccccggcaac accccgcaaa
     2581 aacaaagctg ccatgtgtaa gccgctgatg cagaaccggg gtgtctcctg caaggcggaa
     2641 atgaagtcca aaggaagtca gacagaagag tggaagccac aagtgattgt gctgcccatc
     2701 ccagtgccca tatttgtgcc agtgcctatg catctatact gccagaaagt cccggtgcct
     2761 ttctcaatgc ctatcccggt gcctgtgccc atgttcttgc ccactacctt ggagagcaca
     2821 gagaagatcg tggagaccat tgaggagctg aaggtgaaga tcccttccaa ccccttggag
     2881 gctgacatcc tggccatggc agagatgatt gcagaggccg aagagttaga caaggcctcc
     2941 tcggatcttt gtgatcttgt gagcaaccag agtgcagagg gacttctgga agactgtgac
     3001 ctgtttggga cagctcggga tgatgtcctg gccatggctg ttaagatggc taatgtctta
     3061 gatgagcctg ggcaagactt ggaggctgat ttccccaaga atcctttgga cattaaccca
     3121 agtgtagact tcctctttga ttgtggcctt gtagggcctg aggatgtatc tactgaacag
     3181 gaccttccta gagccatgag gaagggtcaa aagaggctga tgctttctga aagctgttcc
     3241 agggactctc tgagcagcca gcctagttgt actggtctca actattcata cggtgtcaat
     3301 gcttggaaat gctgggtaca gtcaaaatac gccaatggag agaccagcaa aggtgatgag
     3361 ctacgctttg gccccaaacc catgcgtatc aaggaggata ttctcgcctg ttcagctgct
     3421 gagctcaact atggtctggc ccagttcgtg agagaaatca ctcggcccaa tggtgaacga
     3481 tatgaacctg acagtatcta ctacttgtgt cttggcattc agcagtattt gctggaaaat
     3541 aaccggatgg tgaacatttt cacggacctt tactacttga ctttcgttca agaactcaac
     3601 aagtctctga gtacctggca gcccacactc ctccccaaca atactgtatt ctcccgtgtg
     3661 gaggaagaac acctctggga gtgcaagcaa ctgggggttt attctccctt tgtcctcctc
     3721 aataccctca tgttcttcaa cactaagttt tttggactgc agacagctga ggaacacatg
     3781 caactctctt tcactaatgt ggtacggcag tctcgcaagt gtaccacgcc tcggggcacc
     3841 accaaggtgg tgagcatccg ctactatgcc ccagtccgac agaggaaagg gcgagacaca
     3901 ggtcctggga aacgaaagag agaagatgaa actatcttag agcagcgtga gaatcgcatg
     3961 aatcccctcc gctgccccgt caagttctat gagttctatc tctcaaaatg tcctgaaagc
     4021 ctccgaactc gaaatgatgt gttctatctg caacctgagc gctcctgcat tgccgaatca
     4081 cctctctggt attctgtgat tcccatggac cgaagcatgt tggagagcat gctcaatcgc
     4141 attttagctg tgcgtgagat ttatgaggaa cttggtcgtc ctggggaaga agacctagac
     4201 tgagcccatg ttgtaccttg tacccatcta tcacatcagt gtctgtcctg gaaccaatgc
     4261 tatccattct gaagggccct aactggctcc ttctattctc tccttccctg cctttcccag
     4321 gaacccctgc ctttaacctt ctttcatacc acttgataat catgggcccc cagtgtactc
     4381 aggggctagt cccccagtga tgggtgtgaa cctggtagcc cattttgttt atggaaaccc
     4441 tttctgctgg ggcctgactc tgatggagtg atgatagctc tggtgatcct gttggctttg
     4501 cgttttctga cctacatcta tgtaggtgaa gccctgtggc cctaggtgtg acctagggaa
     4561 gaacccagct gccttctctg ccctgtatcc tctctctctc tcctcttccc ctgtaccatg
     4621 tgaaagggtc ttgtctgaga ggtctgaaag tgaggggacc atttacctaa agcacagagc
     4681 tcagacactc ttatccctcc tgagagaagt gattgtcgac accctgcact accacatcca
     4741 ttacctgacc gacccttcca gcaccacaca gtgctacagt ttctcaaggg ttccagatac
     4801 tttctttttc tcaaaggcag agaatgactc agtatggaga gcagactcct attgtgcaga
     4861 tgactcctgt ccccttggtt tatgtgtttg tctctctctg ccatcttaag gtggcgtgaa
     4921 ccatggtgtc aacatgctta acccctctgt aagctgcctc cctttagttc catgaacaga
     4981 gctcccaagg taaaaatgac cttcgcactt agactggggc tgggttcccc aatgttctac
     5041 cccttccatc aaagccaggc ccacagtatg gggtcctagg ccatctagga tggggtttgt
     5101 ggtcaaaaga taggtgagga gctgtgggcc agggtcctac acctactgcc tactgtcttc
     5161 tcttccccat cttacctttg tgggcccaga aaggttagtg tctgtcagag ggagcaccca
     5221 gttctttccc tgttggcttt gctgttcccc agccttcttt ttgtgttttt ataactgtcc
     5281 tcagtttagc cactgttaaa atgtatatat tgtactgagg tgcctggcct gttccttcag
     5341 tgagccatgc ccacccttgt gttgtagtga gaaactgttg tcacaactaa cttgtctctg
     5401 gaattgtttc aaataaagag ttaaaattgt
//
