LOCUS       NM_028601               4053 bp    mRNA    linear   ROD 23-DEC-2022
DEFINITION  Mus musculus zinc finger, MIZ-type containing 2 (Zmiz2), transcript
            variant 1, mRNA.
ACCESSION   NM_028601 XM_006514749
VERSION     NM_028601.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4053)
  AUTHORS   Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK,
            Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L,
            Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre
            JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A,
            Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ,
            Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall
            S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA,
            Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR,
            Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana
            S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, MacArthur DG,
            Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC,
            Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL,
            de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown
            SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M and Murray
            SA.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   2  (bases 1 to 4053)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 4053)
  AUTHORS   Lee SH, Zhu C, Peng Y, Johnson DT, Lehmann L and Sun Z.
  TITLE     Identification of a novel role of ZMIZ2 protein in regulating the
            activity of the Wnt/beta-catenin signaling pathway
  JOURNAL   J Biol Chem 288 (50), 35913-35924 (2013)
   PUBMED   24174533
  REMARK    GeneRIF: a novel interaction between ZMIZ2 and beta-caten
REFERENCE   4  (bases 1 to 4053)
  AUTHORS   Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu
            HS, Brennan J, Armstrong J, Little MH, McMahon AP and
            Southard-Smith EM.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4053)
  AUTHORS   Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND and Robson P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 4053)
  AUTHORS   Peng Y, Lee J, Zhu C and Sun Z.
  TITLE     A novel role for protein inhibitor of activated STAT (PIAS)
            proteins in modulating the activity of Zimp7, a novel PIAS-like
            protein, in androgen receptor-mediated transcription
  JOURNAL   J Biol Chem 285 (15), 11465-11475 (2010)
   PUBMED   20159969
  REMARK    GeneRIF: there is an interaction between Zimp7 and PIAS proteins
            with higher preference for PIAS3, in androgen receptor-mediated
            transcription
REFERENCE   7  (bases 1 to 4053)
  AUTHORS   Rodriguez-Magadan H, Ramirez L, Schnabel D, Vazquez M and Lomeli H.
  TITLE     Sexually dimorphic gene expression of the Zimp7 and Zimp10 genes in
            embryonic gonads
  JOURNAL   Gene Expr Patterns 10 (1), 16-23 (2010)
   PUBMED   19931425
  REMARK    GeneRIF: Zimp7 is expressed in germ cells of the embryonic gonad
            and the adult testis.
REFERENCE   8  (bases 1 to 4053)
  AUTHORS   Rodriguez-Magadan H, Merino E, Schnabel D, Ramirez L and Lomeli H.
  TITLE     Spatial and temporal expression of Zimp7 and Zimp10 PIAS-like
            proteins in the developing mouse embryo
  JOURNAL   Gene Expr Patterns 8 (3), 206-213 (2008)
   PUBMED   18053775
REFERENCE   9  (bases 1 to 4053)
  AUTHORS   Brady KP, Rowe LB, Her H, Stevens TJ, Eppig J, Sussman DJ, Sikela J
            and Beier DR.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK617573.1, CB527314.1, CA318375.1, BC063069.1, W54654.1 and
            AL607152.21.
            
            [WARNING] On Nov 22, 2023 this sequence was replaced by
            NM_028601.4.
            
            On or before Mar 14, 2014 this sequence version replaced
            XM_006514749.1, NM_028601.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7974084.24421.1,
                                           SRR11927934.6686393.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-248               CK617573.1         100-347
            249-921             CB527314.1         1-673
            922-1395            CA318375.1         1-474
            1396-3960           BC063069.1         1-2565
            3961-4049           W54654.1           219-307
            4050-4053           AL607152.21        213374-213377
FEATURES             Location/Qualifiers
     source          1..4053
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.95 cM"
     gene            1..4053
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /note="zinc finger, MIZ-type containing 2"
                     /db_xref="GeneID:52915"
                     /db_xref="MGI:MGI:106374"
     exon            1..164
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            165..275
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     CDS             226..2988
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger MIZ domain-containing protein 2; PIAS-like protein
                     Zimp7"
                     /codon_start=1
                     /product="zinc finger MIZ domain-containing protein 2
                     isoform 1"
                     /protein_id="NP_082877.2"
                     /db_xref="CCDS:CCDS24418.1"
                     /db_xref="GeneID:52915"
                     /db_xref="MGI:MGI:106374"
                     /translation="MNPMNPMKPALPPAPHGDGSFAYESVPWQQSATQPAGSLSVVTT
                     VWGVGNATQSQVLGNPMGPAGSPPGGSMMPGVAGGSSALTSPQCLGQQAFAEGGASKS
                     YVQQGVYGRGSYPGGSSFTTGYAGGPAGLGLPTHAARPSTDFTQAAAAAAMAAAAATA
                     TATATATVAALQEKQSQELSQYGAMGTGQSFNSQFLQHGGPRGPSVPPGMNPSGMGGM
                     MGPSGLSSMAMTPTRAAGMTPLYAGQRLPQHGYPGPPQGQPLPRQGIKRAYSEVYPGQ
                     QYLQGGQYAANTAQYAPGPGQPPGPASSYAGHRLPLQQGMAQSLSAPGPTGLHYKPTE
                     QFNGQGASFNGGSISYSQPGLSGPSRSIPGYPSSPLPGNPTPPMTPSSNVPYMSPSQE
                     VKSPFLPDLKPGLSSLHPSPSASVHCDELRLTFPVRDGVVLEPFRLQHNLAVSNHVFQ
                     LRDSVYKTLMLRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLSIERGDNKTSHK
                     PLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCIT
                     KIKRNFSSGTIPGTPGPNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDL
                     ESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPTCSWKP
                     VPVKPDLHIKEEPDGPVLKRCRTVSPAHVLMPSVMEMIAALGPGAAPFAPLQPPSAPT
                     PSDYPSQGSNFMGPGTFPESFPSATPTTPNLAEFTQGPPPISYQSDIPSSLLTPDKST
                     PCLPGQMAPAGHLDPAHNPGPPGLHTPNLGPTPGTQLHHPNPSPASRQPLGQPNTGPI
                     SELAFNPASGMMGPPSMTGAGEASEPALDLLPELTNPDELLSYLGPPDLPTNSSDDLL
                     SLFENN"
     exon            276..390
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            391..593
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            594..777
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            778..1038
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1218
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1296
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1465
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1610
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1821
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..1927
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2085
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2086..2153
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2154..2222
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2223..2467
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2468..2637
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2880
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
     exon            2881..4053
                     /gene="Zmiz2"
                     /gene_synonym="Zimp7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagagagctg ccaaccaggg gctgggtcag tgcctgtgtc ctgtgtcagc cgtgtcggta
       61 cagccaccct aaggccaacc tggtggatgg actgccgttg tacatctgct gcctgacttt
      121 tcagcatctg cctcaaagaa cactcaagct ctgctccttc tcagccggag cagcaactcc
      181 cggataagct ccagcacatt gggcctgtag gctgctccat caccaatgaa ccccatgaac
      241 cccatgaaac ccgccctgcc ccctgcacca cacggtgatg gttcatttgc atatgagtct
      301 gtgccttggc aacaaagtgc cactcagcca gctgggtcac tgtctgtggt cactactgtg
      361 tggggagttg gcaacgcaac ccagagccag gttttaggga accccatggg ccctgcagga
      421 agcccccctg gtggttccat gatgcctggt gtggcaggtg gcagctctgc cttgacctcc
      481 ccgcagtgcc tgggacagca ggcgtttgct gaaggaggtg ctagcaagag ctacgtacag
      541 caaggcgtgt atggccgagg gagctaccct gggggatcca gcttcactac tgggtatgca
      601 ggaggccctg caggcctggg gctccccaca catgcagcac ggccctcaac tgacttcaca
      661 caagcagcag ctgcagctgc catggctgct gctgcagcca ccgcgacagc cacagccaca
      721 gccacggtgg ctgccctgca ggagaagcag agccaggagc taagtcagta tggagcgatg
      781 gggactgggc agtcttttaa cagccagttt ctgcagcatg gaggtcctcg aggacccagt
      841 gtgccccctg gcatgaaccc ttcaggcatg ggaggaatga tgggcccctc tggcctttct
      901 tcaatggcca tgactcctac ccgggcagca ggcatgacac ccttatatgc aggacagcga
      961 ctgcctcagc atgggtaccc tgggcctccg caggggcagc cactgcctcg acaggggatc
     1021 aagagagcct actcagaggt gtatcctggg cagcagtatc tgcaaggagg ccagtatgca
     1081 gccaacactg cccagtatgc tcctggccct gggcagcccc ctggccctgc ctcctcctat
     1141 gcaggacaca gactacccct gcagcaggga atggcccagt ccctgtctgc gcctggcccc
     1201 acgggactgc attacaagcc cacagagcag ttcaacgggc agggcgccag cttcaacggg
     1261 ggcagcatca gctacagcca gcctggcttg agtgggcctt cccgctccat ccctggttac
     1321 cccagctccc cactgccggg gaatcccaca ccacccatga cgcctagcag caatgttccc
     1381 tacatgtccc caagccagga agtcaagtct cctttcctgc ctgacctcaa gccaggcctc
     1441 agctccttgc acccgtcacc ctccgcaagt gtccattgtg atgagctgcg cctgaccttc
     1501 ccagttcgag atggggtggt cctggagccc ttccgcctgc agcacaacct ggctgtgagc
     1561 aaccatgtct tccagctccg agattctgtc tataagaccc tgatgctgag gcctgacctg
     1621 gagctgcagt ttaagtgcta tcaccatgag gaccggcaga tgaacaccaa ctggccagca
     1681 tctgtgcagg tcagcgtcaa tgccacaccc ctcagcattg agcgtggaga caacaagacc
     1741 tcgcacaagc ccctctacct gaagcatgtg tgccagccag gtcgcaacac catccagatc
     1801 actgtcaccg cctgctgctg ttcccacctc ttcgtgctgc agctggtgca ccgtccgtct
     1861 gtccgttccg tgctgcaggg cctcctcaag aagcgcctat tgccagctga acactgcatc
     1921 accaagataa agcggaactt cagtagcggc accatccctg gcacccctgg gcccaatgga
     1981 gaggatgggg tggagcagac ggctatcaag gtgtccctga agtgccccat caccttccgc
     2041 aggatccagc tcccagcccg tggtcacgac tgtcgacata tacagtgctt tgacctggag
     2101 tcatacttac agctcaactg tgagcggggg acctggaggt gtccggtatg caacaagacg
     2161 gcattgctgg agggcctgga ggtggatcag tatatgctgg gcatcctgat ttatattcag
     2221 aactcagact acgaggagat caccattgac cccacgtgca gctggaagcc agtgcctgtg
     2281 aagcctgacc tacacatcaa ggaggagccg gatgggccag tgctgaagcg ctgccgcact
     2341 gtgagccctg cccatgtgct catgcccagt gtgatggaga tgattgcagc cctgggccct
     2401 ggcgctgccc cttttgcccc attgcagccc ccttcggccc caacccccag cgactatccc
     2461 agccagggtt ccaacttcat ggggcctgga actttcccag aatccttccc atctgctaca
     2521 cccaccaccc caaaccttgc tgagttcacc caggggccac ccccaatctc ctaccagtct
     2581 gacattccca gcagcctcct gactccagac aagtctactc cttgcctccc aggccagatg
     2641 gcaccagcag gccacctgga cccagcccat aatcctggac caccaggact gcacactccc
     2701 aacctcgggc ccaccccagg cactcagcta caccatccaa acccttcccc tgcatcccgg
     2761 cagcccctgg gccaaccaaa cacaggaccc atcagcgaac tggctttcaa tcctgcctca
     2821 ggcatgatgg ggcctcccag catgactggg gcaggggagg cctcagaacc agctttggac
     2881 ctgctcccag aactgaccaa tcctgatgaa ctgctctcct acctgggccc acctgacctc
     2941 cccacaaaca gcagtgatga tctgctctca ctcttcgaga acaactgatc ctgtggtgac
     3001 ccctggcctg gcgaagacac actcaaagat gccaccacag ccttcccttc tcacccagcc
     3061 ccacaggctg cctgctggtt ctccctgaac tcccaatgca cacaccctga gctggggcct
     3121 gccactgcca gccctgatga actggaagca gccctgcgct ccatggggcc ccaggccagt
     3181 gggcctcaca gcctccctcc atcaagctca ctgctccaga atggttcttg tgaggtgcct
     3241 gcaggccccg tcagccccac gtgcacagcc ctctgcccca gactcatggc cttgcacttg
     3301 tccttccacc ctgcctgctc ctacccagcc tgcatcttgt ccagcactga tccttctgtt
     3361 tctgttcctc ctcagcagag ctggctgctg aggctggctc tgtacccttg gtctgcagct
     3421 ccagtgcctg agcctggcag cctcagaacc atacagagca ccagccttag ggggcctggc
     3481 gctcccaccc agctgaatct ggtttagggg ttcctccctc caccctgagc tccaggtgga
     3541 ggctggggtg ggagcaataa agcacaacaa tgtacatagt gtagaaatgc caacagctgg
     3601 gaaagggagg gaccgctatt tcagtcagca tgttcctctg gactggcctg cgccttccat
     3661 gtggtgtctg ccccttactg agcacagaca gctcagggga ggttcaactc ctctaggggt
     3721 gggctttcag gctcagctct atgtaaattc tccagtgagc tgctccccca agtttctctt
     3781 ttctgtgaaa gtgaagaatt agtacagctg tgttttttaa accacctcat ttccaccctg
     3841 cggcccacac ccaggtgggg gaggccattg catctgctgg caaagcgcct gggcctgcaa
     3901 gcagggtgct ggcctgttgt gtctcctgtc tgtgcaatct attaaaggac tccctcttgg
     3961 tgggcttggc tgagtccttc ctttgtgctg agggtctgtg gcctttctgt tcttagaacc
     4021 ccaaataata aaaaatctag atgttttcat cca
//
