LOCUS       NM_001302374            2281 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus zinc finger with KRAB and SCAN domains 6 (Zkscan6),
            transcript variant 2, mRNA.
ACCESSION   NM_001302374 XM_006533716
VERSION     NM_001302374.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2281)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2281)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   3  (bases 1 to 2281)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 2281)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 2281)
  AUTHORS   Mager,J., Schultz,R.M., Brunk,B.P. and Bartolomei,M.S.
  TITLE     Identification of candidate maternal-effect genes through
            comparison of multiple microarray data sets
  JOURNAL   Mamm Genome 17 (9), 941-949 (2006)
   PUBMED   16964442
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK007308.1, BY224975.1, AL596025.22 and BC043075.1.
            
            On Oct 15, 2014 this sequence version replaced XM_006533716.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007308.1, SRR7652917.1277487.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                AK007308.1         1-33
            34-48               BY224975.1         22-36
            49-806              AK007308.1         49-806
            807-807             AL596025.22        21029-21029
            808-1303            AK007308.1         808-1303
            1304-2281           BC043075.1         1335-2312
FEATURES             Location/Qualifiers
     source          1..2281
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 40.53 cM"
     gene            1..2281
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /note="zinc finger with KRAB and SCAN domains 6"
                     /db_xref="GeneID:52712"
                     /db_xref="MGI:MGI:1289293"
     exon            1..87
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     exon            88..574
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1858
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /note="isoform 1 is encoded by transcript variant 2; zinc
                     finger protein 535; zinc finger protein 18; zinc finger
                     protein with KRAB and SCAN domains 6"
                     /codon_start=1
                     /product="zinc finger protein 18 isoform 1"
                     /protein_id="NP_001289303.1"
                     /db_xref="CCDS:CCDS24845.1"
                     /db_xref="GeneID:52712"
                     /db_xref="MGI:MGI:1289293"
                     /translation="MPVDLGQALGPLPFLAKAEDATFSASDATQQRELANPETARQLF
                     RQFRYQVLSGPQETLRQLRKLCFQWLRPEVHTKEQILELLMLEQFLTILPGEIQMWVR
                     KQCPGSGQEAVTLVESLKGEPQKLWHWISTQVLGQEIPFEKENLTHCPGDKLEPALEV
                     EPSLEVAPQDLPLQNSSSATGELLSHGVKEESDMEPELALAASQLPARPEERPVRDQE
                     LGTAVLPPLQEEQWRHLDSTQKEQYWDLMLETYGKMVSGVAGISNSKPDLTNLAEYGE
                     ELVGLHLHGAEKMARLPCKEDRQENDKENLNLENHRDQGCLDVFCQASGEAPPQTALS
                     DFFGESEPHRFGGDSVPEALENHQGEGTGAHLFPYERGSGKQPGQHIQSSSLGELTAL
                     WLEEKREASQKGQARSPMAQKLPTCRECGKTFYRNSQLVFHQRTHTGETYFHCHICKK
                     AFLRSSDFVKHQRTHTGEKPCKCDYCGKGFSDFSGLRHHEKIHTGEKPYKCPLCEKSF
                     IQRSNFNRHQRVHTGEKPYKCTHCGKQFSWSSSLDKHQRSHLGKMPCP"
     exon            575..782
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     exon            783..874
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     exon            875..959
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1073
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..2271
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2032..2037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /note="hexamer: AATAAA"
     polyA_site      2056
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
     regulatory      2246..2251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /note="hexamer: AATAAA"
     polyA_site      2271
                     /gene="Zkscan6"
                     /gene_synonym="1700128E15Rik; D11Ertd714e; KOX11; Zfp535;
                     Znf18"
                     /note="major polyA site"
ORIGIN      
        1 gccccggcgc cgcgcgtcgc cagggccgcg gatgcgcgca gccgtccagc ttccggaagt
       61 gcctcggtga gggtggttag ggccgagcat cggctctcat tcctcaacat cctagaagac
      121 acagttctct ccagagactg ctccatcctg gacgcctctc acctaaaaga tcccgtgaag
      181 ccagacaatg cctgttgact tggggcaggc cctgggcccg cttccttttc tggccaaggc
      241 tgaggatgcc acattctctg catcagatgc tacccagcaa agagagcttg ccaaccctga
      301 gactgctcgc cagcttttca ggcagtttcg ttaccaggtg ctatcggggc cccaggagac
      361 cctgagacaa ctccggaagc tctgtttcca gtggctgcgg ccagaggttc acaccaaaga
      421 gcagatcctg gagctgctca tgctggagca gtttctgacc atcctccccg gggagatcca
      481 gatgtgggtg aggaagcagt gtccaggcag tggacaggag gcagtgacgc tcgtggaaag
      541 cttgaaggga gaaccccaga aactgtggca ctggatcagc acccaagttc taggacaaga
      601 gattccattc gagaaggaga atttgacaca ctgccctggg gacaagttgg agcctgcact
      661 ggaggtggag ccctcactgg aagtggcacc tcaggacctg ccccttcaga attcatcctc
      721 agcaactggg gagctactga gccatggtgt gaaagaggaa tcagacatgg agccagaatt
      781 agctctggct gcttcccagc ttcctgccag acctgaggag aggcctgtta gagaccaaga
      841 gttgggaaca gcagttctcc caccactaca ggaggagcag tggagacacc tggattctac
      901 tcagaaggaa cagtactggg atctcatgct ggagacctat gggaaaatgg tctcaggagt
      961 agcaggcatt tccaactcca aacctgactt gactaactta gcagaatatg gggaagagct
     1021 ggtgggcctg caccttcacg gcgctgagaa gatggcaaga ctcccctgca aagaagacag
     1081 acaagaaaat gacaaagaga acctaaactt ggaaaatcac agggaccagg gatgtctgga
     1141 tgttttctgt caggcatcag gtgaggctcc accacagact gccttgagtg atttcttcgg
     1201 tgagagtgag ccgcatcgct ttggaggaga cagtgtccca gaggctctgg aaaaccatca
     1261 gggtgaggga actggggcgc atctctttcc ttatgaaagg ggctctggga aacagccagg
     1321 tcagcacata cagagctcgt ctttgggaga actgactgcc ttgtggctag aggagaagag
     1381 agaggcctct cagaagggac aggccagatc ccccatggcc cagaaactgc ccacttgcag
     1441 agagtgtggg aaaaccttct ataggaattc acagcttgtt tttcaccaaa ggactcacac
     1501 gggagagaca tactttcatt gccacatttg caaaaaagcc tttctacgaa gctcagactt
     1561 tgtgaaacat cagagaactc acacaggaga gaagccctgt aaatgtgatt actgtgggaa
     1621 aggcttcagt gacttctcag gcttgcgcca ccacgagaaa atccacacag gagagaaacc
     1681 ctataaatgc cccctctgtg agaaaagctt tattcagagg tcaaacttca atagacatca
     1741 aagggttcat acgggtgaga aaccttataa atgtacccac tgtggcaagc agttcagctg
     1801 gagctccagc cttgacaagc atcagagatc acacttgggg aagatgccct gcccatagcc
     1861 acgtccccag gtactacagt ccactgcaag cctgctcacc tctgcctgga agagcttgga
     1921 ccagaaacga cctcctcctc tctgtgtgtt ggagggagag gagctgggca ctgttttgat
     1981 gtggagggga tgttgttctg agttgagtct agtttttctt ttgcaccagg aaataaaaca
     2041 gtttttgttt gtttcagctg gcctcctatt ttggaccccc tgggaaagac atgcagtgta
     2101 gataatgact ttagtagctc tccaatgaga gcctgactgg cttctagagc aggctgtcac
     2161 agaaggggag gtagggtcga ctgtgagtgc atgccatctt tgtcagactg gtgacagagt
     2221 tcctgtctaa ctgtccttta tttgaaataa actgagctga gttggtctct aaaaaaaaaa
     2281 a
//
