LOCUS       NM_016683               3829 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus zinc finger with KRAB and SCAN domains 5 (Zkscan5),
            transcript variant 1, mRNA.
ACCESSION   NM_016683 XM_355663
VERSION     NM_016683.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3829)
  AUTHORS   Spies N, Smith CL, Rodriguez JM, Baker JC, Batzoglou S and Sidow A.
  TITLE     Constraint and divergence of global gene expression in the
            mammalian embryo
  JOURNAL   Elife 4, e05538 (2015)
   PUBMED   25871848
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3829)
  AUTHORS   Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu
            HS, Brennan J, Armstrong J, Little MH, McMahon AP and
            Southard-Smith EM.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3829)
  AUTHORS   Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB,
            Heard E, Lao K and Surani MA.
  TITLE     Deterministic and stochastic allele specific gene expression in
            single mouse blastomeres
  JOURNAL   PLoS One 6 (6), e21208 (2011)
   PUBMED   21731673
REFERENCE   4  (bases 1 to 3829)
  AUTHORS   Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S,
            Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N,
            Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y,
            Okado H, Hashimoto M and Asahara H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3829)
  AUTHORS   Okazaki N, F-Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S,
            Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H,
            Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   6  (bases 1 to 3829)
  AUTHORS   Weissig H, Narisawa S, Sikstrom C, Olsson PG, McCarrey JR, Tsonis
            PA, Del Rio-Tsonis K and Millan JL.
  TITLE     Three novel spermatogenesis-specific zinc finger genes
  JOURNAL   FEBS Lett 547 (1-3), 61-68 (2003)
   PUBMED   12860387
  REMARK    GeneRIF: cloning and characterization of its expression during
            spermatogenesis
REFERENCE   7  (bases 1 to 3829)
  AUTHORS   Shannon M, Ashworth LK, Mucenski ML, Lamerdin JE, Branscomb E and
            Stubbs L.
  TITLE     Comparative analysis of a conserved zinc finger gene cluster on
            human chromosome 19q and mouse chromosome 7
  JOURNAL   Genomics 33 (1), 112-120 (1996)
   PUBMED   8617494
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ769351.1, AK173086.1, AB221634.1 and BC060248.1.
            
            [WARNING] On Nov 18, 2023 this sequence was replaced by
            NM_016683.3.
            
            On Nov 20, 2009 this sequence version replaced NM_016683.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK173086.1, SRR1660817.277942.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-718               BQ769351.1         1-718
            719-736             AK173086.1         714-731
            737-3194            AB221634.1         1-2458
            3195-3829           BC060248.1         2871-3505
FEATURES             Location/Qualifiers
     source          1..3829
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 85.14 cM"
     gene            1..3829
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /note="zinc finger with KRAB and SCAN domains 5"
                     /db_xref="GeneID:22757"
                     /db_xref="MGI:MGI:107533"
     exon            1..1150
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
     CDS             737..3196
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein with KRAB and SCAN domains 5; zfp-95; zinc
                     finger protein 95"
                     /codon_start=1
                     /product="zinc finger protein with KRAB and SCAN domains 5
                     isoform 1"
                     /protein_id="NP_057892.2"
                     /db_xref="CCDS:CCDS39386.1"
                     /db_xref="GeneID:22757"
                     /db_xref="MGI:MGI:107533"
                     /translation="MIMTESRAVIHLEPPAETSQEQADLLIVKVEEEDCSWMQGYNRP
                     VLETFYQRFKHFQYHEAAGPRDALSQLRVLCCEWLRPELHTKEQILELLVLEQFLTIL
                     PEEFQAWVREHHPESGEEAVAVIESIQRELEERRQQIATSPEVLPQKMVPPGATQESF
                     SHQCLPVEAQPERESQNLLEENALPVLQVSSVPLKDSQELTDSLLSDGPQKLVKTEDV
                     ADVAVSFILEEWAHLDQSQKSLGRDSRKEDCESTTPVDYEPKEGNLEFTVQQVSDAAD
                     PHWVAAERTEKNGVQRPESGEVSDLKDMVPRWQVNPTSGNPRQKRPLRSGPDVNRKQK
                     SNGERGHRCGDCGKFFLQASNFIQHRRIHTGEKPFKCGECGKSYNQRVHLTQHQRVHT
                     GEKPYKCQVCGKAFRVSSHLVQHHSVHSGERPYGCNECGKSFGRHSHLIEHLKRHFRE
                     KSQRCSDRRSKNTKLNIKQIPGLSEADLELSGEVQRNACQAEGHSEGCEHQDGQQGVV
                     MKETLGQSSSKRTDCNEFSYVHKKSSPGERPHQCNECGKSFIQSAHLIQHRRIHTGEK
                     PFRCEECGKSYNQRVHLTQHHRVHTGEKPYACHLCGKAFRVRSHLVQHQSVHSRERPF
                     KCNECGKGFGRRSHLAGHLRLHSRDKSHQCHECGEIFFQYVSLLEHQVLHVGQKSEKN
                     GICEEAYSWNLTVIKDKKLELQEQPYQCDSCGKAFSYSSDLIQHYRTHSAEKPQKCDA
                     CRDSTCQCPHIKQQQKSCPSGKSHQCNECGRGFSLKSHLSQHQRIHTGEKPLQCKECG
                     MSFSWSCSLFKHLRSHERTDP"
     exon            1151..1283
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1366
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1502
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..2099
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
     exon            2100..3797
                     /gene="Zkscan5"
                     /gene_synonym="hKraba1; Zfp95"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaaagtgtc ggacttgcct ctctcttggc ttgtgagaac tccatcttcc aagcctgggc
       61 tgcggggagt ttgatctttg ggtccccggg acttaaagac tggagaggag ctggtaggac
      121 attgtgtcca cactggagtc ctgtccctaa ccttgacccg gctggtctct gtctccaggt
      181 caggagctat tacaaagaat ccaggtccaa attttttagt ataaccgtac ttctcataga
      241 actaatgaag tctttcgttt atctatcaag ctcttatggc ttgaaagcca gaatgagata
      301 tgaccatttt aatgggtttc attcctatac tgacttcagt ttggcttatg atcgagagaa
      361 gaaacgactc cgtctggaat aattttgtcc cgttatttat atgagatatg gactttctca
      421 tttttaaaac tgttttaagt tgggcctgat gtcacttttt aatggccttt ttttttttta
      481 cgttattaaa atctggacgt agtcgctatt agctgtttta tgggagaagt gatgactaac
      541 ttctctatat cttaaagtga atgactttgt tgagtggttt ttctttagtc tagatgacgt
      601 cgttgccacc tctcttagct aataataatt ccagacattc cagtaaggtt gttcactaca
      661 aaaagtgccc tttagaagag cagagaacaa atcgggttag tgtaacgggc tagagtctag
      721 agactcttca gttggaatga taatgacaga atccagggca gttatacact tagagcctcc
      781 cgctgagact tcgcaagagc aagcagacct tctcatagtg aaagtagaag aagaggactg
      841 ctcctggatg cagggataca accggccagt gcttgagact ttttaccagc gcttcaagca
      901 cttccagtac catgaggcag caggaccccg cgatgctctc agccagctcc gggttctctg
      961 ttgtgagtgg ctgaggccgg agctgcacac caaagagcag atcctggagc tgctggtgct
     1021 ggagcagttc ctcaccatcc tgcctgaaga gtttcaggcc tgggtgagag agcatcaccc
     1081 cgagagtggg gaagaagccg tggctgtgat agagagtatc cagagagagc tggaggagcg
     1141 cagacaacag attgccacaa gtcccgaagt acttcctcag aagatggtac cacccggagc
     1201 cacgcaggag tccttcagtc accagtgtct acctgtggag gcccagcccg agcgagagtc
     1261 acagaatctt ctggaagaaa atgcccttcc tgttctccag gtttcttccg ttcccctgaa
     1321 ggacagccag gagctgacag attcactcct ctcagatggg ccccagaagt tggtgaaaac
     1381 tgaagatgtg gctgatgtag ctgtgtcctt catcctggag gaatgggcac atttggacca
     1441 gtcccagaag tctctcggta gggacagcag aaaggaggat tgtgagagta ccactcctgt
     1501 ggattacgag cccaaggagg gcaacttaga gttcacggtg cagcaggtct ccgatgcagc
     1561 tgacccacac tgggtggccg cagaacgcac ggaaaagaat ggtgttcagc gtccagagtc
     1621 cggcgaagtc agcgacctga aggacatggt gccgaggtgg caggtgaatc ccacttcggg
     1681 gaatccaagg cagaaaagac ctctgcgctc aggtccggat gttaaccgga agcagaaatc
     1741 gaatggcgaa cgaggccaca gatgtggtga ctgcgggaag tttttcctcc aagcctcaaa
     1801 cttcattcag caccggagga tccacactgg agagaaaccg tttaaatgtg gggagtgtgg
     1861 aaaaagctac aaccagcggg ttcacctcac tcagcaccag agagtccaca ccggcgagaa
     1921 gccctacaag tgtcaggtgt gcgggaaagc cttccgtgtg agctcccatc tggtgcagca
     1981 tcacagcgtg cacagcgggg agaggccgta tggctgtaac gagtgcggga agagctttgg
     2041 gcggcactcg catctgatcg agcatctgaa gcgccacttc agagagaaat cccaaagatg
     2101 cagcgacaga agaagtaaga acactaaact aaacattaag caaattccag gactttcaga
     2161 agcagacctg gaactatcgg gagaagtcca aaggaatgct tgccaggctg aaggtcacag
     2221 tgagggctgt gaacaccagg atggacagca gggggttgtc atgaaagaaa ccctagggca
     2281 gtcctcttca aagaggacag actgcaatga gttcagctat gtccacaaga agtcgtctcc
     2341 aggagagagg ccacaccaat gtaacgagtg cgggaaaagc ttcatccaga gcgcgcacct
     2401 cattcagcat cggagaatcc atactgggga gaaaccattc aggtgcgagg agtgtgggaa
     2461 gagctacaac caacgtgtcc acctcactca acatcaccgc gttcacacgg gcgagaagcc
     2521 ctatgcctgt cacttatgtg ggaaagcctt ccgagtgagg tcccacctcg ttcaacacca
     2581 gagtgtgcac agcagggaga ggcccttcaa gtgcaacgag tgtgggaagg gcttcgggag
     2641 gcgttcgcat ctcgccgggc acctccgact ccactctaga gacaagtcac accagtgtca
     2701 cgagtgtggt gagatctttt tccagtacgt cagcctcctt gaacaccaag tgctccatgt
     2761 gggccagaag agcgagaaga acggtatctg cgaggaggcc tacagctgga acctgacggt
     2821 gatcaaagat aagaagctgg agttacagga gcagccttac cagtgcgact cctgcggcaa
     2881 agccttcagt tacagttctg acctcattca gcattacaga actcactctg cggagaaacc
     2941 ccagaaatgc gacgcatgca gggacagcac ctgccagtgt ccgcacataa aacagcaaca
     3001 gaaaagctgc cccagtggga aatcccatca gtgcaatgag tgtggaaggg gcttcagtct
     3061 gaagtcccat ctcagtcaac atcagagaat ccacaccggc gagaagcccc tccagtgtaa
     3121 ggagtgtgga atgagtttca gttggagctg tagcctcttc aaacatctgc gtagccacga
     3181 gaggacagat ccataagcac ctgaagcata caggagtctg ttgggaagcg gcctggcttt
     3241 agagaagcct tccatggctc tcatatgtgt aacagcatct tagccatctt aaccatcaga
     3301 cctacagacg aggggaagcc ctgtcaggta gagcttagcc ttcagggaca ctggagcatc
     3361 ccaggtgctc cgatagcatc tttacgctcg gaacctctgg ctaggcacgg cggtgctcac
     3421 ctgtatgcct cgggagggag agacaggcaa acatctggtt tacatagcaa gttccaggcc
     3481 agccagatct acatagtgag acccctgggt gagagacaga cagacagaca gacacctctg
     3541 ggtcctgtgg ataaaggaaa gtcttgacat ggcattgttt atttgaagct cagaaaaata
     3601 acaaagagtc atgagtgcag tagacataag ctcatttgta gtttccacct caacagcata
     3661 gctactcaga gagtcgtccc tccaaaggaa ctcttccgcg tgaagcccat cttggtacat
     3721 ctctggacac gactgcccca gccactggag tactctagcc attgtcccat cctgtttatt
     3781 aaaacgtttg aaaagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
