LOCUS       NM_009577               4191 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus zinc finger protein interacting with K protein 1
            (Zik1), mRNA.
ACCESSION   NM_009577
VERSION     NM_009577.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4191)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4191)
  AUTHORS   Memic,F., Knoflach,V., Morarach,K., Sadler,R., Laranjeira,C.,
            Hjerling-Leffler,J., Sundstrom,E., Pachnis,V. and Marklund,U.
  TITLE     Transcription and Signaling Regulators in Developing Neuronal
            Subtypes of Mouse and Human Enteric Nervous System
  JOURNAL   Gastroenterology 154 (3), 624-636 (2018)
   PUBMED   29031500
REFERENCE   3  (bases 1 to 4191)
  AUTHORS   Lumayag,S., Haldin,C.E., Corbett,N.J., Wahlin,K.J., Cowan,C.,
            Turturro,S., Larsen,P.E., Kovacs,B., Witmer,P.D., Valle,D.,
            Zack,D.J., Nicholson,D.A. and Xu,S.
  TITLE     Inactivation of the microRNA-183/96/182 cluster results in
            syndromic retinal degeneration
  JOURNAL   Proc Natl Acad Sci U S A 110 (6), E507-E516 (2013)
   PUBMED   23341629
REFERENCE   4  (bases 1 to 4191)
  AUTHORS   Taher,L., Collette,N.M., Murugesh,D., Maxwell,E., Ovcharenko,I. and
            Loots,G.G.
  TITLE     Global gene expression analysis of murine limb development
  JOURNAL   PLoS One 6 (12), e28358 (2011)
   PUBMED   22174793
REFERENCE   5  (bases 1 to 4191)
  AUTHORS   Borinstein,S.C., Conerly,M., Dzieciatkowski,S., Biswas,S.,
            Washington,M.K., Trobridge,P., Henikoff,S. and Grady,W.M.
  TITLE     Aberrant DNA methylation occurs in colon neoplasms arising in the
            azoxymethane colon cancer model
  JOURNAL   Mol Carcinog 49 (1), 94-103 (2010)
   PUBMED   19777566
  REMARK    GeneRIF: Data indicate that Zik1 and Gja9 demonstrated
            cancer-specific aberrant DNA methylation, whereas, Cdkn2a/p16,
            Igfbp3, Mgmt, Id4, and Cxcr4 were methylated in both the AOM tumors
            and normal colon mucosa.
REFERENCE   6  (bases 1 to 4191)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 4191)
  AUTHORS   Millien,G., Beane,J., Lenburg,M., Tsao,P.N., Lu,J., Spira,A. and
            Ramirez,M.I.
  TITLE     Characterization of the mid-foregut transcriptome identifies genes
            regulated during lung bud induction
  JOURNAL   Gene Expr Patterns 8 (2), 124-139 (2008)
   PUBMED   18023262
REFERENCE   8  (bases 1 to 4191)
  AUTHORS   Denisenko,O.N., O'Neill,B., Ostrowski,J., Van Seuningen,I. and
            Bomsztyk,K.
  TITLE     Zik1, a transcriptional repressor that interacts with the
            heterogeneous nuclear ribonucleoprotein particle K protein
  JOURNAL   J Biol Chem 271 (44), 27701-27706 (1996)
   PUBMED   8910362
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY026558.1, BC050942.1 and AC159008.2.
            
            On Aug 29, 2006 this sequence version replaced NM_009577.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC050942.1, AK146692.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                BY026558.1         15-56
            43-3006             BC050942.1         1-2964
            3007-4191           AC159008.2         69653-70837         c
FEATURES             Location/Qualifiers
     source          1..4191
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 6.47 cM"
     gene            1..4191
                     /gene="Zik1"
                     /note="zinc finger protein interacting with K protein 1"
                     /db_xref="GeneID:22775"
                     /db_xref="MGI:MGI:108070"
     exon            1..240
                     /gene="Zik1"
                     /inference="alignment:Splign:2.1.0"
     exon            241..279
                     /gene="Zik1"
                     /inference="alignment:Splign:2.1.0"
     CDS             247..1638
                     /gene="Zik1"
                     /codon_start=1
                     /product="zinc finger protein interacting with
                     ribonucleoprotein K"
                     /protein_id="NP_033603.2"
                     /db_xref="CCDS:CCDS20792.1"
                     /db_xref="GeneID:22775"
                     /db_xref="MGI:MGI:108070"
                     /translation="MTAEMDMALMQGCVTFQDVAICFSHEEWRLLDETQRLLYLSVML
                     QNFALINSQGCGHKTEDEERRVSTRASKGLRSETTPKTNLCEKCVPILQDILCLPGLP
                     GQKHSTEASSKVDQHQDHNSTGKPLEKNADRSSYLFYLSAKSFPSWDVEKDLPDILSL
                     LKSQVCPKTKKYRKSTEGRKETSHESDKSEECQSLSSQKQTLAHHPKTSNGKKLYECS
                     KCGKTFRGKYSLDQHQRVHTGERPWECRDCGKFFSQTSHLNDHRRIHTGERPYECSEC
                     GKLFRQNSSLVDHQKTHTGARPYECSQCGKSFSQKATLVKHKRVHTGERPYKCSECGN
                     SFSQSAILNQHRRIHTGVKPYECRECGKSFSQKATLIKHQRVHTGERPYKCSECGKSF
                     SQSSILIQHRRIHTGARPYECSQCGKSFSQKSGLIQHQVVHTGERPYECDTCGNSFSQ
                     CSSLIHHQKCHNA"
     exon            280..406
                     /gene="Zik1"
                     /inference="alignment:Splign:2.1.0"
     exon            407..4191
                     /gene="Zik1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4169..4174
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zik1"
                     /note="hexamer: AATAAA"
     regulatory      4173..4178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zik1"
                     /note="hexamer: AATAGA"
     polyA_site      4188
                     /gene="Zik1"
                     /note="major polyA site"
     polyA_site      4191
                     /gene="Zik1"
ORIGIN      
        1 gcgctctgtg gcgctcattt tagcggtttt tgggtccctc cttccagatc gtgtgcaaga
       61 cccctttgtc cagaggtgta cggatcgaag aatctcaaag gagcggttct aagggcgtaa
      121 tattcatcgc agccccggca ctgacagtgg cagtattgtc caggtccctc gtccccgttt
      181 ccccgttgtc tgcgctcgct tacttggatg gctgtgccca cgctcatgca ccaggcttag
      241 gtgtccatga ctgcagaaat ggatatggcc ctcatgcagg gctgtgtgac ctttcaagat
      301 gtggccattt gcttctccca tgaagaatgg agacttcttg atgagactca gaggctcctg
      361 tacctcagtg ttatgctgca gaactttgca ctcataaact cccagggttg tgggcataaa
      421 acagaagatg aagagcgaag ggtttctaca cgagcgtcaa agggtttgag atccgagacc
      481 acaccgaaaa ctaacctctg tgaaaagtgt gtcccgattc tgcaagacat tttgtgcctg
      541 cctggtctac ctgggcagaa acatagtaca gaggcaagtt caaaagttga tcagcaccaa
      601 gaccataata gtacaggaaa acccttggag aagaatgctg acaggtcttc atacctgttc
      661 tacctgtcag caaagtcctt ccccagttgg gatgttgaaa aagacctccc agatatactg
      721 agccttctga agtctcaggt ctgtcccaaa actaagaagt acagaaaaag cactgagggt
      781 aggaaagaaa caagtcatga aagtgacaag tcagaagagt gtcagagcct ttccagtcaa
      841 aagcaaacac ttgctcacca cccaaaaacc tccaatggaa agaaacttta tgagtgcagc
      901 aaatgtggaa agaccttccg tggcaaatac tcccttgatc aacatcagag agtccacacc
      961 ggagagaggc cttgggagtg tagagattgt gggaaattct ttagccagac ctcccacctg
     1021 aatgatcacc gtagaataca cactggagag aggccttatg agtgcagtga atgtgggaaa
     1081 ttatttagac agaactccag tcttgttgat caccagaaaa ctcatactgg agcaagacca
     1141 tatgagtgta gccagtgtgg gaagtccttt agtcaaaaag ctacacttgt taaacacaag
     1201 agagttcaca ctggagaaag gccttacaag tgtagtgagt gtgggaattc ctttagtcaa
     1261 agtgccattc ttaaccaaca ccggagaatt cacactggag taaagcctta tgaatgtaga
     1321 gaatgtggga aatcttttag ccaaaaagct acccttatta aacaccagcg agttcacact
     1381 ggagaaaggc cttacaagtg tagtgagtgt gggaaatctt tcagtcaaag ctccatcctt
     1441 attcaacacc ggagaattca tacaggagca aggccctatg agtgtagcca gtgtggaaag
     1501 tcctttagcc aaaagtccgg tctcattcag catcaggtag ttcacactgg agaaaggcca
     1561 tatgaatgtg acacatgtgg gaattctttt agtcagtgct ctagcctcat tcatcaccaa
     1621 aaatgtcata acgcttaaga aacctcatga aagcagcaaa tgtggataag ccttcagctg
     1681 aaggcctaac atcatttagc tcctccaaat ccgtacttga gaaaaagcct tagatttata
     1741 gggaatgccc tctttttggt tttgcttttg ttttttgttt tttaaagtac tatgacacta
     1801 gaacctttgc agaggatcca actacaatgt aaggttgatc ttccagtatc caggaatcag
     1861 attcctcagg aattcaggca caagtaggtt cagcaactgc tttgcccatc ctgaactggc
     1921 caagaccttt gccatttttg taccagtgtt tgtggtagaa gctatcagtc gttctctacc
     1981 acatgaccag tgtgcaatga ttacaccatc atggtaagga aaggcaaact gcagattgcc
     2041 tggaagaatt cttcaatgga ggatttatgg aaaattggtc ccccagtttt aactgattaa
     2101 aatgtggata tgactaagat ttcaccaaga agatcaaatt tattgtctgc taaagatgtc
     2161 tagaatttgc ttccctgctt cttttaaaaa gtagctttta atctgtgtca catgacagtt
     2221 aggtgaatgt ttccagcctt ctgattatca gttggtcact gccttctccc cgttgctctg
     2281 atttgtacac tgataaatgc cttatcccta aagctacctt actcttaaga gtgcagttta
     2341 ctaagtggga aggctggtaa acagactgat cattttagga aagaatggaa agcttttata
     2401 gagggtctca acttggttta cctctgcacg gacagcaaaa taaagaaagc aaatttgtat
     2461 tgcttcccag gccaacagct gggacttctt tattatagtt tatgaataac tgaataagta
     2521 ttcatgtaca tgaagatcta gttgaaaact ttctgtgatc atctcaagaa gatgtctgtt
     2581 atttccataa gctcctttac ttgtggaaat gaaatgaatt ggctcatttc tttttctcaa
     2641 aggatgtcct aaaaatgcct atgatgcaga gagacagctc ataaagctgt ataaagagtg
     2701 tgcctggata ggaattattc cataggcacc agccaataag atgaccactc atgaggtgat
     2761 cagagctaga tgtgaatcat cattggcata caaaagatgg gtatagtgga gtcttcagcc
     2821 agccagatgg aatgtgactc ttttaaaagt gcacacaatc tttgtctttg gctgaattca
     2881 caggacttaa agatctttgt atttacaata gctgaggtca ttgtcaaaaa tggtatggtt
     2941 ttgtgggata gtggagttta acttgatcat ttacctccag tcttgttata gagataggaa
     3001 aataaggaaa tgaagattct ttagtcttag aatgtagctg ttataattgc attccagctg
     3061 ctgtgtttgc agtctggtat tcacaaatgt ctctgccatt tcctgcatta acaaaaggct
     3121 gcccttatct gtatatgagg acagagttca atcaaaatgg gggataccaa gccttctggt
     3181 ttgcagaaat taggagttct gagctttgta ctttgagtca ctttttataa agtttatcaa
     3241 tgttttagtg aaatgcagtc aactctgatt tatccttgaa aaaaatctta aaatcatctt
     3301 tgtgatgatg gacttgtctg tgacttacct caccctgtta agatctccct tgtgttctcg
     3361 gacttgtaag tgttgaatag cttatatttg gctcttaaga gtgcagtttg tgaatgaaaa
     3421 caaaaggttt tttttcctta gatacagtgt cttttaggaa tacataatta ttttgagatt
     3481 catcactgct gctttttaat aactttatag tgctatacca tgtttggttt tgtaactata
     3541 caacaattta ttgatctttt ttattcattc ggctcttggt tgaatccttt cttgagctgt
     3601 tacatattat ggatatgagc atttgattca atatgcttac atttttaaat tcctctcgag
     3661 ccagtaatta agtatatgtg aatgcttcta tttttaagaa agtgtcaaac tggtatagat
     3721 tgctctagat cagtggttct caacctttct gatgctgcaa ttctttaata cagttcctca
     3781 tgctgtggta accctcaacc atagaattat ttttgttgct acttcacaac tgtaattttg
     3841 ctgctggtat gaattgtaaa tatttgtgtt ttcctatggt cttaggtgac acctgtgaaa
     3901 gggtcatttg actcccaaaa gggtcacgac ccattgagaa caactgatgt agacagtgta
     3961 tgaacattct tgctagtact tgtgtggtta atgagtttgc tttgagccat ttgaatagct
     4021 gtataataac acactgtata gtcttaattg cttttttcgt gtttcatgat actgaatatt
     4081 tttgtgtgtt tacttgccaa gtgtattttt taaaacttgt ttttttgcct attttcaagt
     4141 gaaaattcat gttactgtcc ttttcattaa taaatagatg tacactaaca a
//
