LOCUS       NM_009573               5606 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus zinc finger protein of the cerebellum 1 (Zic1),
            transcript variant 1, mRNA.
ACCESSION   NM_009573 XM_904863
VERSION     NM_009573.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5606)
  AUTHORS   Velez-delValle,C., Hernandez-Mosqueira,C.P., Castro-Rodriguez,L.I.,
            Vazquez-Sandoval,A., Marsch-Moreno,M. and Kuri-Harcuch,W.
  TITLE     Gene expression and characterization of clonally derived murine
            embryonic brown and brite adipocytes
  JOURNAL   FEBS Open Bio 14 (9), 1503-1525 (2024)
   PUBMED   38972757
REFERENCE   2  (bases 1 to 5606)
  AUTHORS   Chen,Z., Snetkova,V., Bower,G., Jacinto,S., Clock,B., Dizehchi,A.,
            Barozzi,I., Mannion,B.J., Alcaina-Caro,A., Lopez-Rios,J.,
            Dickel,D.E., Visel,A., Pennacchio,L.A. and Kvon,E.Z.
  TITLE     Increased enhancer-promoter interactions during developmental
            enhancer activation in mammals
  JOURNAL   Nat Genet 56 (4), 675-685 (2024)
   PUBMED   38509385
REFERENCE   3  (bases 1 to 5606)
  AUTHORS   Choi,J.S., Ayupe,A.C., Beckedorff,F., Catanuto,P., McCartan,R.,
            Levay,K. and Park,K.K.
  TITLE     Single-nucleus RNA sequencing of developing superior colliculus
            identifies neuronal diversity and candidate mediators of circuit
            assembly
  JOURNAL   Cell Rep 42 (9), 113037 (2023)
   PUBMED   37624694
REFERENCE   4  (bases 1 to 5606)
  AUTHORS   Sampath Kumar,A., Tian,L., Bolondi,A., Hernandez,A.A., Stickels,R.,
            Kretzmer,H., Murray,E., Wittler,L., Walther,M., Barakat,G.,
            Haut,L., Elkabetz,Y., Macosko,E.Z., Guignard,L., Chen,F. and
            Meissner,A.
  TITLE     Spatiotemporal transcriptomic maps of whole mouse embryos at the
            onset of organogenesis
  JOURNAL   Nat Genet 55 (7), 1176-1185 (2023)
   PUBMED   37414952
REFERENCE   5  (bases 1 to 5606)
  AUTHORS   Wang,W.X., Qiao,J. and Lefebvre,J.L.
  TITLE     PV-IRES-Cre mouse line targets excitatory granule neurons in the
            cerebellum
  JOURNAL   Mol Brain 15 (1), 85 (2022)
   PUBMED   36274179
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5606)
  AUTHORS   Aruga,J., Minowa,O., Yaginuma,H., Kuno,J., Nagai,T., Noda,T. and
            Mikoshiba,K.
  TITLE     Mouse Zic1 is involved in cerebellar development
  JOURNAL   J Neurosci 18 (1), 284-293 (1998)
   PUBMED   9412507
REFERENCE   7  (bases 1 to 5606)
  AUTHORS   Nagai,T., Aruga,J., Takada,S., Gunther,T., Sporle,R., Schughart,K.
            and Mikoshiba,K.
  TITLE     The expression of the mouse Zic1, Zic2, and Zic3 gene suggests an
            essential role for Zic genes in body pattern formation
  JOURNAL   Dev Biol 182 (2), 299-313 (1997)
   PUBMED   9070329
REFERENCE   8  (bases 1 to 5606)
  AUTHORS   Miyata,T., Nakajima,K., Aruga,J., Takahashi,S., Ikenaka,K.,
            Mikoshiba,K. and Ogawa,M.
  TITLE     Distribution of a reeler gene-related antigen in the developing
            cerebellum: an immunohistochemical study with an allogeneic
            antibody CR-50 on normal and reeler mice
  JOURNAL   J Comp Neurol 372 (2), 215-228 (1996)
   PUBMED   8863127
REFERENCE   9  (bases 1 to 5606)
  AUTHORS   Aruga,J., Nagai,T., Tokuyama,T., Hayashizaki,Y., Okazaki,Y.,
            Chapman,V.M. and Mikoshiba,K.
  TITLE     The mouse zic gene family. Homologues of the Drosophila pair-rule
            gene odd-paired
  JOURNAL   J Biol Chem 271 (2), 1043-1047 (1996)
   PUBMED   8557628
REFERENCE   10 (bases 1 to 5606)
  AUTHORS   Aruga,J., Yokota,N., Hashimoto,M., Furuichi,T., Fukuda,M. and
            Mikoshiba,K.
  TITLE     A novel zinc finger protein, zic, is involved in neurogenesis,
            especially in the cell lineage of cerebellar granule cells
  JOURNAL   J Neurochem 63 (5), 1880-1890 (1994)
   PUBMED   7931345
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY261991.1, BC063247.1, CN666056.1, AK141431.1 and CD741655.1.
            
            On Dec 5, 2019 this sequence version replaced NM_009573.3.
            
            Transcript Variant: Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159769.1, BC063247.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-133               BY261991.1         33-165
            134-3092            BC063247.1         127-3085
            3093-3319           CN666056.1         277-503
            3320-5600           AK141431.1         653-2933
            5601-5606           CD741655.1         13-18               c
FEATURES             Location/Qualifiers
     source          1..5606
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 48.26 cM"
     gene            1..5606
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /note="zinc finger protein of the cerebellum 1"
                     /db_xref="GeneID:22771"
                     /db_xref="MGI:MGI:106683"
     exon            1..1733
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /inference="alignment:Splign:2.1.0"
     CDS             752..2095
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /note="Zic family member 1 (odd-paired homolog,
                     Drosophila)"
                     /codon_start=1
                     /product="zinc finger protein ZIC 1"
                     /protein_id="NP_033599.2"
                     /db_xref="CCDS:CCDS23403.1"
                     /db_xref="GeneID:22771"
                     /db_xref="MGI:MGI:106683"
                     /translation="MLLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGM
                     GAFKLNPSSHELASAGQTAFTSQAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDFLF
                     RNRGFGDAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFSGLHEQAAGHASPNVVN
                     GQMRLGFSGDMYPRPEQYGQVTSPRSEHYAAPQLHGYGPMNVNMAAHHGAGAFFRYMR
                     QPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEEC
                     PREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKC
                     EFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQGSQ
                     PSPAASSGYESSTPPTIVSPTTDNPTTSSMSPSSSAVHHTAGHSALSSNFNEWYV"
     exon            1734..1897
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..5606
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3144..3149
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /note="hexamer: ATTAAA"
     polyA_site      3164
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
     regulatory      5577..5582
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /note="hexamer: ATTAAA"
     polyA_site      5606
                     /gene="Zic1"
                     /gene_synonym="ZIC; ZNF201"
                     /note="major polyA site"
ORIGIN      
        1 atcagtctcg cgctcaccgc ccggctgagg aggtgaaagt ttctccccag gaagataaac
       61 cgcaaaagac aatattgtgc atgatttgcg ccttttcttt tcttttttct ccccctcctt
      121 tttttttttt tttcaaaaag cagagagggg gaaaaaggga gagttgaagg atcgaggagg
      181 agagcctgag agagagagag agagagagag agagagagag agaagagaga gagagagaga
      241 gagagagaga gagagagaga gagtgagaga gagagagact gagactagtg gagaagtgag
      301 gaggggcgcg ctgcgcgagg agacagggcg agcagtggcg gctctggcgt tcacattcct
      361 ctatgccaca aatccgggaa gaagttttat tggggggctg agatgttcta tgcctttccc
      421 cgggcagcct tgattcgagg ccctctcggc agagactgag cggcgagaaa gtgagagccc
      481 ggcccgcgcg gttcgagcgg ctggcgctgg agcccgcctt ctaccggccg gcagtcatct
      541 ctcttgcctg cctttggccg ggcgggtgcc ggctagcgcc tggccgttgc ctgctggctg
      601 agacttcgtt aggtgggtcg actccccctc cctcctcctc ttcttcctcc tcttcctccg
      661 cctcccgttc ctcctcctcc tgatcttccc tccttggcgg gcgagggtgg gggggggcgg
      721 gggaggccgg ggcttgcccc gtgcagccac gatgctcctg gacgccggac cccagtatcc
      781 cgcgattggt gtgaccacct ttggtgcatc ccggcaccac tcggcgggcg acgtggccga
      841 gagagacgtg ggcctgggta tcaacccgtt cgccgacggc atgggcgcct tcaagctcaa
      901 ccccagttcg cacgaactgg cctcggctgg ccagacagcc ttcacgtcgc aggctccggg
      961 ctacgccgct gctgcggccc tgggccacca tcaccacccc ggccacgtcg gctcctactc
     1021 cagcgctgct ttcaattcta cccgggactt tctgttccgc aaccggggct tcggcgacgc
     1081 ggcggcggca gctagcgccc agcacagtct cttcgctgct tcggccggcg gctttggggg
     1141 cccacacggc catacggacg ccgcgggcca cctccttttt tctgggcttc acgagcaggc
     1201 ggctggccac gcttcgccca acgtggttaa cgggcagatg cggctaggtt tctccgggga
     1261 catgtaccca cggccggaac agtacggcca ggtgaccagc ccgcgatccg agcactatgc
     1321 tgccccgcag cttcacggct atgggcccat gaacgtgaac atggctgcac atcacggggc
     1381 tggagccttc ttccgctata tgcgccaacc catcaagcaa gagcttatct gtaaatggat
     1441 cgagccggag cagctggcca accccaaaaa gtcgtgcaac aaaactttca gcaccatgca
     1501 cgagctggtc acgcacgtca cggtggagca cgtcggcggc ccagagcaga gcaaccacat
     1561 ctgcttctgg gaggagtgtc cacgcgaggg caagcccttc aaagccaaat acaaactggt
     1621 caaccacatc cgagtgcaca caggcgaaaa gccttttccc tgcccgtttc ctggctgcgg
     1681 caaggttttc gcgcgttcag agaacctcaa gatccacaaa aggacacaca caggggagaa
     1741 gcccttcaag tgcgagttcg agggctgcga ccggcgcttc gccaacagca gcgaccgcaa
     1801 gaagcacatg cacgtgcaca cgagcgacaa gccctacctt tgcaagatgt gcgataagtc
     1861 ctacacgcac cccagctctc tgcgtaaaca catgaaggtc catgagtcct cttctcaggg
     1921 ctcacagcct tcgcccgccg ccagctcggg gtatgagtcg tccacgccac ccaccatcgt
     1981 gtctcccaca acagacaacc cgaccaccag ctccatgtcg ccctcctcct ccgcggttca
     2041 ccacacagcc ggccacagcg cgctctcttc caattttaac gaatggtacg tttaaaatca
     2101 gaaacaaaac atgccgaccc cctatttaag agactgaaca cacacgtata tacgccgtat
     2161 tattgaaaga atcctgaaac tcgagacacc cctcgtcccg atcccgcaaa cgtttttatt
     2221 tttatttttg ttgttgttgt tgtttgtttg attttgtttt taaatctgcc ggtaaatcca
     2281 ggactgagta aaacagagga ggcagcaagc ctttaggttt tttcactcca aatttttcct
     2341 tcccccaccc acctctgaaa aggtttggta gctgaagggc ggaagggggt ggaagagaag
     2401 gcggctgcct gaccgaacac cgccaaaggc cccagggcca atttcttgtt ggatcagaac
     2461 aagctctctg gggcttcagc ttttctttat ctttttgttt tgttttcttg taaatacaga
     2521 attattagct taaatctgtt ctgttggatt ctgtatatag ctacacttcg gttggagtgg
     2581 gtgggtggga tcgtggcgtg gtggtctttg ccttggggag gggagggcca gagggagggg
     2641 gagggggagg ggaggggcgg ccgaaagcca actgtttgta ctgaatggca agaatgttct
     2701 agtaaatgtg taccaaaatg tgaactactt tgtacgatta cagtctccac gtcgacctaa
     2761 cagaatatta ttgatattaa tgtgcttttt tttgtataaa gtgcaaacat ttcgtcccaa
     2821 agtctgagta ctttagtgca gtaaaatgtt gtttcatgtc ctgtcaagaa ttcgtatagt
     2881 acgagcctgg atctacgtgt caaactgttc catttgttta tgtaaagtga tattaaaaag
     2941 atataaacta tagctgtcca ttgcttttgg caaaatatac aaccacacaa tgtatataat
     3001 tcctagtttc catatttatc cgcatgtaaa gggtctggtt tattcatgtt acagctattc
     3061 aatatttatg gctagtaaaa aaaaaaaaaa aactcgtatg tacactttag tttccagaac
     3121 tgtttggtaa cctttcgtac gttattaaag attcttaaat ctcagtgatt gtggtaggaa
     3181 tttcttcgtc acgctccctt cccccagcaa cctgtgccag ctttagtgga tcttgggaaa
     3241 gctctccagc ctctcttgcc ttcttctctg tcattgctgg tcatataaac ttgataaatg
     3301 aacgctaccc tgctggctct ccgagagggt gtaattagta tttatatcaa aatttatgaa
     3361 acaaattttc ggcctcagta taatttaaat gacctttgca gacatagaat aacaaccata
     3421 aaaataacgg aaatagattg cacaggcaac atcaatatta atgtaagcga attgtgagaa
     3481 gctcgggggc tctttctgta gccttgcaaa tgaacttaca gtcattcaag ggttcagctg
     3541 cccccccaat taaatcccct gatctgaaac tggattgtag atttacaata ttatatttta
     3601 aattgctgtc ttcaattaaa ccattatggc cataactaat tttcaggatg ccgatgcatg
     3661 cttttccagg ccttccatct ttgtacaaaa gtaaatgtcc ataaagcgtt tcacttatat
     3721 tttttcaaac gtgatgctaa tttaaattaa ttacttccta tgatatatta ttattctata
     3781 attttgctac tgtcattagt tctctcaaaa atacatctag aaaagagaat tattttatgt
     3841 aatgtgatta tctttctatc tcttttattt atttctcatt tacttaagaa attcgttcca
     3901 ttggctggcg ttgatacagt aaatttgtaa atgaggagac aatataaaaa atctaaatta
     3961 cttgtgctta atgactgtgg cagaacgcct tttctctaaa tcagattgtc tttcttgcag
     4021 tttagtttga tagatttgca agctatgctg cttcggagaa gttaggttct ctggtaggga
     4081 tgctggtttc tttgtctctt gttgtcgctt gcatgatcgc cccattaggc agacaacgta
     4141 gctagaactc acaaatcagg cccttggcta tggctgcagg ggtgtagatg tgttaggagt
     4201 caggggaagc atgattctgc ttctccactg tcctctgtat gtcctgcaag ttacaggcct
     4261 aaggagaccc ttctgagagc tttacatgtg tttcacagca atagcaactt gagaaactaa
     4321 accactagct aattatacaa taaaaatatt atcatcgtga aagacacctc ttgctacttg
     4381 tatttctcac gtttagtcaa caaagtctta tttacggata aaaggttttg ctgtgttaac
     4441 ttcatcagtt tcttttttaa tagaaaaggg tggggatatt gatgtttaac tgtaaagaac
     4501 aaagtttctc tgcttataac agcgatattg gatattggcc ttttgtacaa agagcgctat
     4561 cttgtaaaat ttgttgagat tttggaaagt taaataccta aggaagagtt gctgtcaacc
     4621 ctaaaaaaaa ttgttacatt aaaacctgga tctcagtagc tttggaggtt gaagactgat
     4681 caacagtgtt gcatttaaag tgacagtaga cagtgagccc aacattaaac acaggaagag
     4741 gaatagagag ttcatctttc taggaacaac aacagatcca ttaataatct ttccctcttt
     4801 ttattaaaga tgagggtttt ctgggaaact gttgtgtata tgatgatagt tttaacagca
     4861 cttttgtgat tttctcagag catttaagaa gacagcatag gagtttatct ttgatttgac
     4921 tatttctaaa tttaagttta cttcgaattt gaaattctgt ctgattgtta tgtacctggt
     4981 gctcttttgc tttaatatta tagtataatg atcaaacatc acactatgac atatgattta
     5041 cataaactat ttaaaataca tattagaaat aagtgagttt tcttttcaaa tttcagaaat
     5101 tcatgtagat ttttaaggtc aaataatttt attaccactt gagaaccccc tgtatgtatt
     5161 tatgaataat ctcacagcaa aggaactttt ataataagag acaacattta tgtcaatccc
     5221 cctttgcatt gttttctcta atgtcctcca caaagaaaaa gtcattaatg atgtaagtca
     5281 ccaaaataat gctttaaact taaatgtagt ctattatttt gctggcacct ttaatgtctg
     5341 cttcttgaga tgtattcttc atacttttct tcatgggcta ttaggttttg aaatacatga
     5401 atgtgaacag tgaaatatat tgttagactc tatttagcag gagctgaaga ctctgcaaat
     5461 ggctggtttc tatgtgtagt tgtggatttt gatctaggca gaaggccata ttggttcata
     5521 ttgcatactg cattgtattc tggatactac caaatgatta ggacagctaa caagttatta
     5581 aaatgttatt ttgtgtcaac agaaaa
//
