LOCUS       NP_932114               1863 aa            linear   ROD 30-APR-2024
DEFINITION  5'-3' DNA helicase ZGRF1 [Mus musculus].
ACCESSION   NP_932114 XP_485308 XP_986851
VERSION     NP_932114.2
DBSOURCE    REFSEQ: accession NM_197997.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 1863)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 1863)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
REFERENCE   3  (residues 1 to 1863)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC079891.1, AK046429.1 and CO044435.1.
            
            On or before Jul 8, 2009 this sequence version replaced
            XP_986851.2, XP_485308.3, NP_932114.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 56.54 cM"
     Protein         1..1863
                     /product="5'-3' DNA helicase ZGRF1"
                     /EC_number="5.6.2.3"
                     /note="GRF-type zinc finger domain-containing protein 1;
                     protein ZGRF1"
                     /calculated_mol_wt=205607
     Region          3..75
                     /region_name="DUF2439"
                     /note="Protein of unknown function (DUF2439); pfam10382"
                     /db_xref="CDD:463065"
     Region          1109..1153
                     /region_name="zf-GRF"
                     /note="GRF zinc finger; pfam06839"
                     /db_xref="CDD:462017"
     Region          <1493..1818
                     /region_name="DNA2"
                     /note="Superfamily I DNA and/or RNA helicase [Replication,
                     recombination and repair]; COG1112"
                     /db_xref="CDD:440729"
     CDS             1..1863
                     /gene="Zgrf1"
                     /gene_synonym="4930422G04Rik"
                     /coded_by="NM_197997.2:237..5828"
                     /db_xref="CCDS:CCDS51066.1"
                     /db_xref="GeneID:71643"
                     /db_xref="MGI:MGI:1918893"
ORIGIN      
        1 mecqefivly thqkmkkskv wqdgvlkith lgnkailydd kgacleslfl kclevkpgdd
       61 leserylitv eeakavgsra vepdgsreal esgsrtlvss srslgcqpsg lkrkatgfqr
      121 pykmpkkvti tensepaasl gdenpgppgp rllptfsstl plfptvgqkd ltpvstdnqs
      181 pitfsnrers dtplslpssy fkintntlgk edklcfpvss etkhsdslla sepmrrngld
      241 shcpgvsqnv rskaqilall kssstnrkdl hgeipghfpk iepqgclnii skpeedyaet
      301 qsignlrceq qsenptrtts rwarylpsqr sppcsaaden dtedkpeaqe dvnifnlsel
      361 lqkkselfet cskkgelhse dkpvdntcqy wnqednlaps fcknssvlvs csskenasll
      421 sesdiqyssk vpvnqhekvw tregsqgada daalepeyrp vsplpeighk qteveaslst
      481 ssrisddiad mgsksnadre dlktvhkavq pflevsfnls nfetsdtdea sqedsrlsqd
      541 serwekeavl tddscvqksc edigcreivg klpllsstdd epkealpadg tllsefcdrt
      601 cvgfnsgphg dvktgkaleg qchsdtgssl dsslewsedv agdsredasq siqgnaincg
      661 gvspskkprg vnrslyspyl ltavtdpape nsdllseark spaievsral lecpcehras
      721 qqpvefqghq vkgsatsgvm vrghslqrgc tqfpdsidye nfltdtcvwt pglpstygqt
      781 dflqvispeq kipalspapt fsfntrnedt vlelseeslk trtlpglkti gfqdsknlqr
      841 fpflsgasap fatlpaddgp avldpcsfmi dddarepsgs smlnlceesg lsfdlglegq
      901 ggtpggvsll pksstqskwl kyqnppqcns tapnrlasev teglfaeavs glhfshtses
      961 essvdpvrlq mikgllhqqq qdlvsrkqaf sltlnqtckt qehetvlgss askncrakdl
     1021 qeinnsdlcf pngqkiisay lpqrqvhipa vfqspahyrq vftasiiehl nillfelaqr
     1081 lykalskvdi sfytsskget mrsgknnsps chhnqpaklv mvkkegpnkg rlfytcdksk
     1141 dnqckffkwl eevtpgqlpq ntsqstmvfn diksigsylr sqkvpvyeec qlllrrgfdf
     1201 qrkqcgklkk lttvnpdfys etkskiylkl srresssvys kgdlwviskt ldfeldtfia
     1261 csaffgpssv nevellplkg yfpsnwptni tvhallvcna stelttlqni qdyfnpaalp
     1321 lmpyllamsq satvssknis krkfippait siktktelhl gatlqlarel invhrlnkdq
     1381 ataliqiaqm masqgsdeda lepfghslpi tvihgvfgag ksyllavvil flvelfekcd
     1441 sgtvgnarpw kvlvssstnv avdrvllgll slgfekfirv gsvrkiakpv lpyslhagsd
     1501 neseqlkeln allkeeltpi ervyvrksie qhklgtnrvl lkqvrvvgvt caacafpcln
     1561 dlkfpvvvld ecsqmtepas llpiarfqce klilvgdpkq lpptiqgsda ahengleqtl
     1621 fdrlclmghk pvllrtqyrc hpaisaiand lfyegslvng isererspvl ewlptlcfyn
     1681 vtgaeqvere nsfvnvaeat ftlkliqslm asgvescmig vitlyksqmy kicnllsavd
     1741 vghpdvkavq vstvdafqga ekeitilscv rtrqvgfids ekrmnvaltr grrhllivgs
     1801 lsclrknrlw grviqhcegr edglqhasqc epqldhllkd ylekqaeekq kkkekekskd
     1861 ksh
//
