LOCUS       NM_011766               4974 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus zinc finger protein, multitype 2 (Zfpm2), transcript
            variant 1, mRNA.
ACCESSION   NM_011766
VERSION     NM_011766.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4974)
  AUTHORS   Broman,M.T., Nadadur,R.D., Perez-Cervantes,C., Burnicka-Turek,O.,
            Lazarevic,S., Gams,A., Laforest,B., Steimle,J.D., Iddir,S.,
            Wang,Z., Smith,L., Mazurek,S.R., Olivey,H.E., Zhou,P., Gadek,M.,
            Shen,K.M., Khan,Z., Theisen,J.W.M., Yang,X.H., Ikegami,K.,
            Efimov,I.R., Pu,W.T., Weber,C.R., McNally,E.M., Svensson,E.C. and
            Moskowitz,I.P.
  TITLE     A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2
            Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network
  JOURNAL   Circulation 149 (15), 1205-1230 (2024)
   PUBMED   38189150
  REMARK    GeneRIF: A Genomic Link From Heart Failure to Atrial Fibrillation
            Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory
            Network.
REFERENCE   2  (bases 1 to 4974)
  AUTHORS   Leon,N.Y., Le,T.N.U., Garvie,A., Wong,L.H., Bagheri-Fam,S. and
            Harley,V.R.
  TITLE     Y chromosome damage underlies testicular abnormalities in ATR-X
            syndrome
  JOURNAL   iScience 27 (5), 109629 (2024)
   PUBMED   38616920
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4974)
  AUTHORS   Galazo,M.J., Sweetser,D.A. and Macklis,J.D.
  TITLE     Tle4 controls both developmental acquisition and early post-natal
            maturation of corticothalamic projection neuron identity
  JOURNAL   Cell Rep 42 (8), 112957 (2023)
   PUBMED   37561632
REFERENCE   4  (bases 1 to 4974)
  AUTHORS   Funk,O.H., Qalieh,Y., Doyle,D.Z., Lam,M.M. and Kwan,K.Y.
  TITLE     Postmitotic accumulation of histone variant H3.3 in new cortical
            neurons establishes neuronal chromatin, transcriptome, and identity
  JOURNAL   Proc Natl Acad Sci U S A 119 (32), e2116956119 (2022)
   PUBMED   35930666
REFERENCE   5  (bases 1 to 4974)
  AUTHORS   Kirjavainen,A., Singh,P., Lahti,L., Seja,P., Lelkes,Z.,
            Makkonen,A., Kilpinen,S., Ono,Y., Salminen,M., Aitta-Aho,T.,
            Stenberg,T., Molchanova,S., Achim,K. and Partanen,J.
  TITLE     Gata2, Nkx2-2 and Skor2 form a transcription factor network
            regulating development of a midbrain GABAergic neuron subtype with
            characteristics of REM-sleep regulatory neurons
  JOURNAL   Development 149 (14) (2022)
   PUBMED   35815619
REFERENCE   6  (bases 1 to 4974)
  AUTHORS   Lu,J.R., McKinsey,T.A., Xu,H., Wang,D.Z., Richardson,J.A. and
            Olson,E.N.
  TITLE     FOG-2, a heart- and brain-enriched cofactor for GATA transcription
            factors
  JOURNAL   Mol Cell Biol 19 (6), 4495-4502 (1999)
   PUBMED   10330188
REFERENCE   7  (bases 1 to 4974)
  AUTHORS   Morsli,H., Tuorto,F., Choo,D., Postiglione,M.P., Simeone,A. and
            Wu,D.K.
  TITLE     Otx1 and Otx2 activities are required for the normal development of
            the mouse inner ear
  JOURNAL   Development 126 (11), 2335-2343 (1999)
   PUBMED   10225993
REFERENCE   8  (bases 1 to 4974)
  AUTHORS   Fox,A.H., Liew,C., Holmes,M., Kowalski,K., Mackay,J. and
            Crossley,M.
  TITLE     Transcriptional cofactors of the FOG family interact with GATA
            proteins by means of multiple zinc fingers
  JOURNAL   EMBO J 18 (10), 2812-2822 (1999)
   PUBMED   10329627
REFERENCE   9  (bases 1 to 4974)
  AUTHORS   Svensson,E.C., Tufts,R.L., Polk,C.E. and Leiden,J.M.
  TITLE     Molecular cloning of FOG-2: a modulator of transcription factor
            GATA-4 in cardiomyocytes
  JOURNAL   Proc Natl Acad Sci U S A 96 (3), 956-961 (1999)
   PUBMED   9927675
REFERENCE   10 (bases 1 to 4974)
  AUTHORS   Tevosian,S.G., Deconinck,A.E., Cantor,A.B., Rieff,H.I.,
            Fujiwara,Y., Corfas,G. and Orkin,S.H.
  TITLE     FOG-2: A novel GATA-family cofactor related to multitype
            zinc-finger proteins Friend of GATA-1 and U-shaped
  JOURNAL   Proc Natl Acad Sci U S A 96 (3), 950-955 (1999)
   PUBMED   9927674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC163008.9, AC101996.9, AC158556.9 and AC102004.7.
            
            On Oct 19, 2007 this sequence version replaced NM_011766.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF125166.1, AF118845.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-542               AC163008.9         6782-7323           c
            543-701             AC101996.9         111970-112128
            702-803             AC101996.9         133119-133220
            804-922             AC158556.9         180432-180550       c
            923-1034            AC158556.9         96274-96385         c
            1035-1241           AC102004.7         75614-75820         c
            1242-1466           AC102004.7         72368-72592         c
            1467-4974           AC102004.7         67287-70794         c
FEATURES             Location/Qualifiers
     source          1..4974
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 15.74 cM"
     gene            1..4974
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /note="zinc finger protein, multitype 2"
                     /db_xref="GeneID:22762"
                     /db_xref="MGI:MGI:1334444"
     exon            1..542
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     CDS             503..3958
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     friend of GATA-1 2; zinc finger protein ZFPM2; mFOG-2;
                     friend of GATA-2; friend of GATA protein 2; Friend of GATA
                     2"
                     /codon_start=1
                     /product="zinc finger protein ZFPM2 isoform 1"
                     /protein_id="NP_035896.1"
                     /db_xref="CCDS:CCDS27447.1"
                     /db_xref="GeneID:22762"
                     /db_xref="MGI:MGI:1334444"
                     /translation="MSRRKQSKPRQIKRPLEDAIDDEEEECPVEEAEVISKGDFPLEG
                     SFPAGFEPENLSCEDVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGE
                     LEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNSLKTKAQVPMVLTAGPKWLLDV
                     TWQGVEDSKNNCIVYSKGGQLWCTTTKAISEGEELVAFVVDFDSRLQAASHMTLTEGM
                     YPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGR
                     QREAAPVSEENEDNSHQVSSLCPFPQCTKSFSNARALEMHLNSHSGVKMEEFLPPGAS
                     LKCTVCSYTADSVINFHQHLFSHLTQAAFRCNHCHFGFQTQRELLQHQELHVPSGKLP
                     RESDMEHSPSGTEDSLQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLT
                     NQRPEIQPAANKQNFSYTKIKSEPSSPRLASSPVQPNIGPSFPVGPFLSQFAFPQDIT
                     MVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPLMPKGATCFECNITFNNLDNYLVH
                     KKHYCSSRWQQMAKSPEFPSVSEKMPEAVSPNTGQTSINLLNPAAHSSDPENPLLQTS
                     CINSSTVLDLIGPNGKGHEKDFSTQVKKLPTSNSSDDKINGKPVDVKNPSGPLVDGES
                     DPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSASNKVPAMQRTMRTRKRRK
                     MYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKH
                     LETSLAMNKCVPVPKCDTTHSNVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHEC
                     TVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERSSPEVSFERNMI
                     KCEKNGNPKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAI
                     KKTKGADQLSPYYGIKPSDYIASSLVIHNTDVEQSTNTENESPKGQASSNGCAVPKKD
                     SLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNTQHEDGHKSPSWISENPLAANE
                     NVSPGIPCAEEQLSSIAKGVNGASQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHA
                     AEHVK"
     exon            543..701
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            702..803
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            804..922
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            923..1034
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1241
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1466
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..4974
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4947..4952
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /note="hexamer: AATAAA"
     polyA_site      4970
                     /gene="Zfpm2"
                     /gene_synonym="B330005D23Rik; FOG-2; FOG2"
                     /note="major polyA site"
ORIGIN      
        1 gcgcggcgcg gcccggagcg gcagcggcgg cgcctgagtc tctgcccggc agccggggac
       61 acggagagcg agcgcgcgcc tcctcccgca ccctccgccc ctcgcagccc gggtccccct
      121 gcgctctctc ctcccctccc tccttctctt ccttctctta cccctccacc cccttcttcc
      181 ccttttctct ctgcctggcc gatcgctcct agattcccat cctccccccc acagccccat
      241 cgctctatcc gtcgccccct cccctcttcc ctgtcacact ctctctgccc cttgctcggc
      301 ctctcatttg cttgctcatc tccaaacgtg gatccgccgc tcccggagga gcctagctcc
      361 gggatcccga gcgcacggag cacctggagt ccgaccggcg gcggcccgag cctgcccaga
      421 ggcagaggcg gcgacaaccc agggaaccgt agcgggaacc gcagacaccg caggaacccc
      481 agcggcagcg gccgcggccg aaatgtcccg gcgaaagcag agtaaacccc ggcagatcaa
      541 acggccgctg gaagatgcca tcgacgacga ggaagaagag tgtccggtgg aggaagccga
      601 agtcatctcg aaaggcgact ttccactgga gggaagcttc cccgcaggct ttgagcccga
      661 aaatctgagc tgcgaagacg tggagttctt ttgtaacaaa ggtgatgacg aaggaatcca
      721 ggagccagca gaatcagatg gggacagcca ttcagacaaa ccaggacagc ctggggtaga
      781 gacagatgac tgggatggac caggagagct agaagtgttt cagagagatg gagaaaggaa
      841 gattcagagt cggcagcaac ttccggtggg aacaacctgg ggcccttttg ctgggaagat
      901 ggacttgaac aataattcct tgaagacgaa ggctcaggtc cccatggtgc tgactgctgg
      961 tcctaaatgg cttctggatg tgacatggca aggagtggaa gacagcaaaa acaactgcat
     1021 tgtgtacagc aaagggggcc aactttggtg caccacaacg aaggccatct cagagggtga
     1081 agagctcgtc gcctttgtgg tggactttga ctcaaggcta caagctgcta gtcacatgac
     1141 tctcaccgaa gggatgtacc ctgcccgcct gctggactcg attcagctgc ttcctcagca
     1201 agctgccatg gcttctattt tgcctacagc tattgtcaat aaggatatat tcccttgcaa
     1261 gtcctgtggc atctggtacc ggagcgagcg gaacctgcaa gcccatttga tgtactactg
     1321 tagtgggagg caacgagaag ctgctccagt gtcagaagaa aatgaagaca actcgcatca
     1381 ggtttccagc ctgtgcccct tcccacaatg caccaagagc ttttccaatg cccgagctct
     1441 agaaatgcac ctgaattcac acagtggtgt gaaaatggaa gagttcctgc cccctggggc
     1501 gagtttaaaa tgcacggtct gtagctacac tgctgattct gtgatcaact tccaccaaca
     1561 cctgttctcg catctcactc aagccgcctt ccgatgcaac cactgccatt ttggctttca
     1621 gacccagagg gagctactgc agcaccagga gctccatgtc cccagtggca aacttcccag
     1681 agaaagtgac atggagcact ctccaagtgg aacggaagac agcttacagc cagccacaga
     1741 cttgttggcc agaagtgacc tctcccagag ccaaaaggcc atgccgacta aggatgcaag
     1801 ctcagacaca gagctggaca agtgtgagaa aaagactcaa ctcttcctca ccaatcagag
     1861 accagagatc cagcctgcag ccaacaagca aaacttctct tacacaaaaa taaagtctga
     1921 gccctccagt cccagactcg cctcatctcc agtgcaaccc aacatcgggc cctctttccc
     1981 tgtgggacct ttcctgtctc agtttgcttt tccccaagat atcacgatgg tccctcaggc
     2041 ttcagagatc ttggcgaaga tgtccgagct ggtgcaccgt cgactgaggc atgggagtag
     2101 tagctaccct cctgtgattt acagcccttt gatgcccaaa ggggctacgt gctttgagtg
     2161 taacataaca ttcaataatt tggataacta tctagttcat aaaaagcact actgcagcag
     2221 cagatggcag cagatggcca aatcccctga gtttccaagt gtttctgaaa aaatgcctga
     2281 ggctgtgagt cctaacactg gccagacttc cataaacctt cttaacccag ccgctcattc
     2341 atcggaccca gagaacccac tccttcaaac atcctgcatc aactcttcca ccgttttaga
     2401 tttgattggg ccaaacggga aaggccatga gaaggacttt tccactcaag tcaaaaagtt
     2461 gcccacctcc aacagtagtg acgacaaaat aaacggaaag cctgttgatg tgaaaaatcc
     2521 cagcggtccc ttagtggatg gggaaagtga cccaaataag actacctgtg aagcttgtaa
     2581 catcaccttt agcaggcatg aaacctatat ggtccacaaa cagtattact gtgcaacacg
     2641 ccatgaccct ccgctaaaga ggtctgcttc caacaaagtg ccggccatgc agagaaccat
     2701 gcgcacacgc aagcgaagaa agatgtacga aatgtgccta cctgagcagg aacagcggcc
     2761 gcccctggtc cagcagagat ttcttgatgt agccaaccta agcaatcctt gtagctccac
     2821 tcaagagccc accgaagggc taggagaatg ctaccaccca agatgcgaca tcttcccagg
     2881 aattgtctct aagcacttgg aaacatcatt ggccatgaac aaatgtgttc cggttcccaa
     2941 gtgtgacacg acccattcca atgtttcctg cttggagatg gatgtcccta tagatctcag
     3001 caaaaagtgt ttatcgcagt ctgagcggac gacagcatct cctaagaggc tactagacta
     3061 ccacgagtgc acagtgtgca agatcagctt caataaggtc gagaactatc tggcgcacaa
     3121 gcagaatttc tgccctgtca ctgcacatca gcgtaatgac ctgggtcagc ttgatggtaa
     3181 agtgtttccg aatccagaaa gtgaacggag cagccctgaa gtcagctttg aaagaaacat
     3241 gatcaaatgt gagaagaatg ggaatccaaa gcaaccatct cccaacggaa atttgttttc
     3301 atcccacttg gcaaccttgc aaggcctgaa agtcttcagc gaagcagctc agctcattgc
     3361 tacaaaagaa gaaaacaaac atttgtttct tccccaatgc ctttaccctg gagcaataaa
     3421 gaagacaaaa ggagctgacc aactttctcc atactatggg ataaagccaa gcgattatat
     3481 cgccagttct cttgtcatcc acaacactga cgtcgaacaa agcacaaata cagaaaatga
     3541 atctcctaaa ggccaggcct cctcaaatgg gtgtgccgta cccaagaaag attctctgcc
     3601 attgttgccc aaaaacagag gcatggtcat agtgaatggt ggactcaagc aagatgaaag
     3661 acctacggcc aacccacagc aagagaacat ttcccagaat acccagcacg aagatggcca
     3721 caaatcccct tcgtggatct ctgagaaccc attagctgca aatgagaatg tctccccagg
     3781 aattccctgc gcagaagaac agttgtctag catagcaaaa ggtgtgaatg gcgccagcca
     3841 ggctcccagc agtggaaaat actgccggct atgcgatatt cagttcaata atctttcgaa
     3901 ctttataact cacaagaagt tttattgctc atcacatgca gcagaacatg tcaaatgaac
     3961 taactgagtt actaaagaaa gcagtcacct ttggtacccg tgtttagtat gttcttctaa
     4021 acagtccaga aaacaaagac gctgtttgaa ttacatctgg caatcaggag ataattcatt
     4081 atggctgaat tgaagactta aggtgtaatt tcattacaga ccattagtaa agtgtattat
     4141 tggtgccatt ttcagaaaaa aaaattaatt tattttacca gcagtattca tagctgtggt
     4201 tatgttattt ttatttaaaa actttatatt aaagtcattt gtaatgattg tatagttctt
     4261 gtgtagcaca tatggtttgc actgtatagt agcttttaaa gaaaatagtc acaaacaata
     4321 cagaagagca ttttagaaat agcttcaaaa gcacttgtgt attctgattt tttcttatat
     4381 gctgttgcag atattcgtat atgctaaaat ataacctgca aacatgttct aaatacacat
     4441 gctataagtt cgccttaaga tttcaattct tggataatca ggctccaatt gcactttata
     4501 ttttagcaaa tacagtctct tagtcactag gctttgcatt cgtatgtagc cgtatatttc
     4561 tgtccatttt ctcaaacaga aacatgtatg ttaagtgaag atggcatttc tttcttgtat
     4621 agtacttgta ttttctttcg ccgatgcagc cctgtctcaa tttttcaacc tttgctgtta
     4681 aatgcaatac tttataaaga atgaacaaaa ttactggaag cagtattgtc agtaatggag
     4741 tagtattcac cagttttatc ttttgaaagg cacagtctaa atcgaacccc taaactcaat
     4801 gctgcaagta tgaatttaat tcatatataa gatctattta aatataagag tagcaatact
     4861 gcacctggtg atcacaaaga taatgttcta cttctgatag aaataatttc tcaacaaatg
     4921 ttgttactat gcatgtacat ggatggaata aaattccaaa ttgttggaga cgtt
//
