LOCUS       NM_009569               4001 bp    mRNA    linear   ROD 14-MAY-2024
DEFINITION  Mus musculus zinc finger protein, multitype 1 (Zfpm1), mRNA.
ACCESSION   NM_009569 XM_916387
VERSION     NM_009569.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4001)
  AUTHORS   Guo,P., Lim,R.C., Rajawasam,K., Trinh,T., Sun,H. and Zhang,H.
  TITLE     A methylation-phosphorylation switch controls EZH2 stability and
            hematopoiesis
  JOURNAL   Elife 13, e86168 (2024)
   PUBMED   38346162
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4001)
  AUTHORS   Kirjavainen,A., Singh,P., Lahti,L., Seja,P., Lelkes,Z.,
            Makkonen,A., Kilpinen,S., Ono,Y., Salminen,M., Aitta-Aho,T.,
            Stenberg,T., Molchanova,S., Achim,K. and Partanen,J.
  TITLE     Gata2, Nkx2-2 and Skor2 form a transcription factor network
            regulating development of a midbrain GABAergic neuron subtype with
            characteristics of REM-sleep regulatory neurons
  JOURNAL   Development 149 (14) (2022)
   PUBMED   35815619
REFERENCE   3  (bases 1 to 4001)
  AUTHORS   Yogosawa,S., Ohkido,M., Horii,T., Okazaki,Y., Nakayama,J.,
            Yoshida,S., Toyokuni,S., Hatada,I., Morimoto,M. and Yoshida,K.
  TITLE     Mice lacking DYRK2 exhibit congenital malformations with lung
            hypoplasia and altered Foxf1 expression gradient
  JOURNAL   Commun Biol 4 (1), 1204 (2021)
   PUBMED   34671097
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4001)
  AUTHORS   Tikker,L., Casarotto,P., Singh,P., Biojone,C., Piepponen,T.P.,
            Estartus,N., Seelbach,A., Sridharan,R., Laukkanen,L., Castren,E.
            and Partanen,J.
  TITLE     Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal
            Development of Dorsal Raphe Serotonergic Neuron Subtypes and
            Increased Anxiety-Like Behavior
  JOURNAL   J Neurosci 40 (45), 8669-8682 (2020)
   PUBMED   33046550
  REMARK    GeneRIF: Inactivation of the GATA Cofactor ZFPM1 Results in
            Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes
            and Increased Anxiety-Like Behavior.
REFERENCE   5  (bases 1 to 4001)
  AUTHORS   Gudmundsdottir,B., Gudmundsson,K.O., Klarmann,K.D., Singh,S.K.,
            Sun,L., Singh,S., Du,Y., Coppola,V., Stockwin,L., Nguyen,N.,
            Tessarollo,L., Thorsteinsson,L., Sigurjonsson,O.E., Gudmundsson,S.,
            Rafnar,T., Tisdale,J.F. and Keller,J.R.
  TITLE     POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin
            and Human Fetal Hemoglobin Expression
  JOURNAL   Cell Rep 23 (11), 3236-3248 (2018)
   PUBMED   29898395
REFERENCE   6  (bases 1 to 4001)
  AUTHORS   Crispino,J.D., Lodish,M.B., MacKay,J.P. and Orkin,S.H.
  TITLE     Use of altered specificity mutants to probe a specific
            protein-protein interaction in differentiation: the GATA-1:FOG
            complex
  JOURNAL   Mol Cell 3 (2), 219-228 (1999)
   PUBMED   10078204
REFERENCE   7  (bases 1 to 4001)
  AUTHORS   Fox,A.H., Kowalski,K., King,G.F., Mackay,J.P. and Crossley,M.
  TITLE     Key residues characteristic of GATA N-fingers are recognized by FOG
  JOURNAL   J Biol Chem 273 (50), 33595-33603 (1998)
   PUBMED   9837943
REFERENCE   8  (bases 1 to 4001)
  AUTHORS   Tsang,A.P., Fujiwara,Y., Hom,D.B. and Orkin,S.H.
  TITLE     Failure of megakaryopoiesis and arrested erythropoiesis in mice
            lacking the GATA-1 transcriptional cofactor FOG
  JOURNAL   Genes Dev 12 (8), 1176-1188 (1998)
   PUBMED   9553047
REFERENCE   9  (bases 1 to 4001)
  AUTHORS   Tsang,A.P., Visvader,J.E., Turner,C.A., Fujiwara,Y., Yu,C.,
            Weiss,M.J., Crossley,M. and Orkin,S.H.
  TITLE     FOG, a multitype zinc finger protein, acts as a cofactor for
            transcription factor GATA-1 in erythroid and megakaryocytic
            differentiation
  JOURNAL   Cell 90 (1), 109-119 (1997)
   PUBMED   9230307
REFERENCE   10 (bases 1 to 4001)
  AUTHORS   LaRosa,G.J. and Gudas,L.J.
  TITLE     Early retinoic acid-induced F9 teratocarcinoma stem cell gene
            ERA-1: alternate splicing creates transcripts for a
            homeobox-containing protein and one lacking the homeobox
  JOURNAL   Mol Cell Biol 8 (9), 3906-3917 (1988)
   PUBMED   2906112
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121976.2.
            
            On Jan 24, 2017 this sequence version replaced NM_009569.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF006492.1, SRR7345562.1304774.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-382               AC121976.2         64157-64538         c
            383-505             AC121976.2         41199-41321         c
            506-655             AC121976.2         39038-39187         c
            656-789             AC121976.2         22846-22979         c
            790-889             AC121976.2         14490-14589         c
            890-1096            AC121976.2         12752-12958         c
            1097-1327           AC121976.2         11997-12227         c
            1328-1423           AC121976.2         11652-11747         c
            1424-1570           AC121976.2         11420-11566         c
            1571-4001           AC121976.2         8817-11247          c
FEATURES             Location/Qualifiers
     source          1..4001
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 70.86 cM"
     gene            1..4001
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /note="zinc finger protein, multitype 1"
                     /db_xref="GeneID:22761"
                     /db_xref="MGI:MGI:1095400"
     exon            1..382
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     CDS             343..3330
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /note="FOG-1; friend of GATA protein 1; Friend of GATA 1"
                     /codon_start=1
                     /product="zinc finger protein ZFPM1"
                     /protein_id="NP_033595.1"
                     /db_xref="CCDS:CCDS22733.1"
                     /db_xref="GeneID:22761"
                     /db_xref="MGI:MGI:1095400"
                     /translation="MSRRKQSNPRQIKRSLRDMEAGEEAKAMDSSPKEQEAPDPEAPA
                     IEEPPSPPREDVSPPAVPAPPESPEDPEDMEGQELEMRPQDEEKEEKEEEAAMASPWS
                     GPEELELALQDGQRCVRARLSLTEGLSWGPFYGSIQTRALSPEREEPGPAVTLMVDES
                     CWLRMLPQVLTEEAANSEIYRKDDALWCRVTKVVPSGGLLYVRLVTEPHGAPRHPVQE
                     PVEPGGLAPVHTDIQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERNLQAHLLY
                     YCASRQRAGSPVSATEEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFV
                     CLICLSAFTTKANCERHLKVHTDTLSGVCHNCGFISTTRDILYSHLVTNHMVCQPGSK
                     GEIYSPGAGHPAAKLPPDSLAGFQQHSLMHSPLVPADKAPTPSSGLDSKAEVTNGETR
                     VPPQNGGSSESPAAPRTIKVEAAEEPEATRASGPGEPGPQAPSRTPSPHSPNPVRVKT
                     ELSSPTPGSSPGPGELTMAGTLFLPQYVFSPDAGTTTVPTAPQASEILAKMSELVHNR
                     LQQGAGSSGAAGTPTGLFSGTKGATCFECEITFNNINNFYVHKRLYCSGRRAPEDPPT
                     VRRPKAATGPARAPAGAAAEPDPSRSSPGPGPREEEASGTTTPEAEAAGRGSEGSQSP
                     GSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPPAPTTAPGPA
                     APALTAPPVRTRRRRKLYELPAAGAPPPAAGPAPVPVVPSPTAELPSSPRPGSASAGP
                     APALSPSPVPDGPIDLSKRPRRQSPDAPTALPALADYHECTACRVSFHSLEAYLAHKK
                     YSCPAAPLRTTALCPYCPPNGRVRGDLVEHLRQAHGLQVAKPAASPGAEPRTPAERAP
                     RDSPDGRAPRSPSPAPENTPSDPADQGARTPSKGPPAPAPAPGGGGGHRYCRLCNIRF
                     SSLSTFIAHKKYYCSSHAAEHVK"
     exon            383..505
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            506..655
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            656..789
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            790..889
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1096
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1327
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1423
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1570
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..4001
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3367..3372
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /note="hexamer: AATAAA"
     polyA_site      3390
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /note="major polyA site"
     regulatory      3980..3985
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
                     /note="hexamer: AATAAA"
     polyA_site      4001
                     /gene="Zfpm1"
                     /gene_synonym="FOG; Fog1"
ORIGIN      
        1 cctggcggcg gccgccggtt cgccgctcgc ggctcgcagg ttccattgag aaaagctgag
       61 cggcggcggc ggcggcgtct gcgccggagc agagaagccg ccaccagccc gccgcccgcc
      121 gggcagtccg cgcgcccgag cgcagggccg tggcctcggg cctccgcggc ggcgccggcg
      181 gcccacgcgc ggcgcggcgg gctgggggcg cgggccgagg cagccgtgga gcccgcgggc
      241 cgggggcatg agccgccccg ctaccccgcc gcgcccctgc cgcccgccgc cgcccgccag
      301 gggctagagg cggccgccgc gagggcgcgc ggcgccggag acatgtccag gaggaaacag
      361 agcaatcccc ggcagatcaa gcgttccctc agagacatgg aggccggaga agaagccaag
      421 gccatggaca gcagccccaa ggagcaggaa gccccagacc cagaggcccc agccatagag
      481 gagcccccaa gtccacccag agaagatgtg agcccacctg cagtgccggc acctccggag
      541 tccccagaag atcctgagga catggagggg caggagttgg agatgaggcc ccaggatgaa
      601 gagaaagagg aaaaggaaga agaggcagcc atggctagtc cctggagtgg gccagaggag
      661 ctggagctgg cactgcagga tgggcagagg tgcgtgcgcg cccggctgag cctcactgag
      721 ggcctatcct ggggcccatt ctacgggagc atccagacca gagccttatc ccctgagaga
      781 gaagaaccgg gcccagctgt gaccctgatg gtggatgaga gctgctggct aaggatgctg
      841 ccccaggtcc taactgaaga agccgccaac tcagagatct acaggaagga tgacgccctc
      901 tggtgcaggg ttaccaaagt ggtgccttct ggtggactgc tatatgtgcg ccttgtcacc
      961 gagccccatg gtgctcccag acaccctgtg caggaaccag tagaacctgg aggcttggcc
     1021 ccagtgcaca ccgacatcca gctgctgccc cagcaggctg gcatggcatc catccttgct
     1081 accgcagtca tcaacaagga cgtcttcccc tgcaaagact gcgggatctg gtaccgtagt
     1141 gagcggaacc tgcaagccca cctgctctac tactgtgcca gccgccagcg tgcaggctct
     1201 cctgtctcgg cgacggaaga gaaacccaaa gagacctacc ccaatgagcg tgtctgcccc
     1261 ttcccccagt gccgaaagag ctgccccagc gccagctcgc tggagatcca catgcgcagc
     1321 cacagtggag agcgcccctt cgtgtgcctc atctgcctgt cggccttcac caccaaggcc
     1381 aactgtgaac gccatctcaa ggtgcacaca gacacgctca gcggtgtctg tcacaactgt
     1441 ggcttcatat ccaccacaag ggacatcctc tacagtcacc tggtgacaaa ccacatggtg
     1501 tgccagccag gctccaaggg tgagatctac tcaccagggg ctggacaccc agcagccaaa
     1561 cttcctccag acagcctggc aggctttcaa cagcactcgc tgatgcacag ccccctggtt
     1621 cccgctgaca aggcacccac cccatcctca ggactggaca gtaaggccga agtcaccaac
     1681 ggagagacca gagtgccccc ccaaaatggg ggcagcagtg agtcccctgc agcccccagg
     1741 accatcaagg tggaggctgc agaggagcct gaagccaccc gtgcctccgg tccgggagag
     1801 ccaggtcccc aggctccgtc tcggacacct tcaccacaca gccccaatcc agtcagggtg
     1861 aagacagaac tgtccagccc cacgcctggc tctagcccag ggccgggaga gctaacaatg
     1921 gccgggacac tctttctgcc acaatatgtg ttcagtccgg acgcgggcac aaccaccgtc
     1981 cctacggcgc cacaggcctc ggagatcctg gccaagatgt ccgagttggt gcacaaccgg
     2041 ctacagcagg gtgcagggag ctccggcgca gcgggaacac ccactggcct cttctcgggg
     2101 actaagggtg ccacgtgctt tgagtgcgag atcaccttta acaatatcaa caacttctat
     2161 gtgcacaagc gcctctactg ctcgggccgc cgcgcgcccg aggacccgcc cactgtgcgc
     2221 agacccaaag cggccaccgg cccggcccgc gcgcccgcag gtgccgccgc agagccagac
     2281 ccgtcacgct cgtcgccggg gcccgggcca cgagaggaag aggcgagtgg cacgactact
     2341 ccggaggccg aggccgcggg ccggggcagc gagggcagcc agagcccggg cagctccgta
     2401 gacgacgcag aggacgatcc gagccgcacg ctgtgcgagg cctgcaacat ccggtttagc
     2461 cgccacgaaa cctacactgt gcacaagcgc tactactgcg cctcgcgcca cgacccgccg
     2521 ccgcgccggc cacccgcacc cacgaccgca ccgggacccg cggctcctgc gctgacagcg
     2581 ccacccgtgc gcacgcgccg gcgtcgcaag ctgtacgagc tgcccgcagc tggcgccccg
     2641 cccccagccg caggccccgc ccctgtgcca gttgtaccct cccccactgc ggagctgccc
     2701 tcttctccga gacctgggag cgccagcgcc ggccctgccc ccgcgctctc tccgagcccg
     2761 gtccccgacg gccccataga cctgagcaag cggccgcgtc gccagagccc ggatgcacca
     2821 acagctctgc ccgcgctggc cgactaccac gagtgtaccg catgtcgcgt aagcttccac
     2881 agcctcgaag cttacctggc tcacaagaag tactcatgcc ccgccgcgcc tttgcgcacc
     2941 actgccctct gcccctactg cccgcccaac gggcgcgttc gcggcgacct ggttgagcat
     3001 ttgcgccagg cacacggcct gcaggtggcc aagccagcgg ccagcccggg cgctgagccc
     3061 cgcacacctg ccgagcgtgc tccgcgcgac agccccgacg gccgcgcacc acgctctcct
     3121 tcccctgctc ccgagaatac gccttctgac ccagcagatc aaggcgctcg gacacccagc
     3181 aagggcccgc cagctcctgc tcctgcgccg ggtggtggtg gcggccaccg ctactgccgc
     3241 ctgtgcaaca tcaggttcag cagcctgtcc actttcatcg cgcacaagaa gtattactgc
     3301 tcttctcacg ccgccgagca cgtaaagtga gcctgtgggg ccgcaccacc aggacccttg
     3361 acacttaata aagacattcg gtgtgataaa ttcgctggag gcccagcctg ttgtcttaga
     3421 tctagtgggc ctcattccat accccagctt gtgcggccct gcaaagggca ccccaccgtt
     3481 tcctccagga cttagcccgc tccagggatt caaccgcccc tgcagagttc ttttcctctg
     3541 cctctagctc acccgctgcc ctgccagaaa gtgcatccaa ttgcagacta ctagagagag
     3601 tgaaaccttg ttcttgctga gtcttcgaga aagaggacca agtcccaaag tgcccctccc
     3661 gtcacaacag gggtgggtac ttatgactac agagttgggc ctgggtatac cccctgtagt
     3721 ccgtggctgg ccggctgtag gccacgtctg gcagaaccaa agcaatggca gtctagccat
     3781 tgctttggcc tctctgcttg gtcccctgag aaggtgtgaa catggctgtt ctccaactct
     3841 gtaagtctta accggcagct gtagaagctg acagagagcc ctgaaaatac cataccccaa
     3901 ggacccgggc cctgtcggcc agtccacctc tcctgcagcc ttctgaggcg gcctgctgat
     3961 ggacctgggt ttacacaaga ataaatgttc ctgagagtcc a
//
