LOCUS       NM_011764               3698 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 90 (Zfp90), transcript variant 2,
            mRNA.
ACCESSION   NM_011764
VERSION     NM_011764.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3698)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3698)
  AUTHORS   Yu,C.Y., Han,J.X., Zhang,J., Jiang,P., Shen,C., Guo,F., Tang,J.,
            Yan,T., Tian,X., Zhu,X., Ma,D., Hu,Y., Xie,Y., Du,W., Zhong,M.,
            Chen,J., Liu,Q., Sun,D., Chen,Y., Zou,W., Hong,J., Chen,H. and
            Fang,J.Y.
  TITLE     A 16q22.1 variant confers susceptibility to colorectal cancer as a
            distal regulator of ZFP90
  JOURNAL   Oncogene 39 (6), 1347-1360 (2020)
   PUBMED   31641208
REFERENCE   3  (bases 1 to 3698)
  AUTHORS   Liu,T., Kong,W.X., Tang,X.Y., Xu,M., Wang,Q.H., Zhang,B., Hu,L.D.
            and Chen,H.
  TITLE     The transcription factor Zfp90 regulates the self-renewal and
            differentiation of hematopoietic stem cells
  JOURNAL   Cell Death Dis 9 (6), 677 (2018)
   PUBMED   29880802
  REMARK    GeneRIF: Zfp90 was highly expressed in hematopoietic stem cells.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3698)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3698)
  AUTHORS   Taher,L., Collette,N.M., Murugesh,D., Maxwell,E., Ovcharenko,I. and
            Loots,G.G.
  TITLE     Global gene expression analysis of murine limb development
  JOURNAL   PLoS One 6 (12), e28358 (2011)
   PUBMED   22174793
REFERENCE   6  (bases 1 to 3698)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   7  (bases 1 to 3698)
  AUTHORS   Marine,J.C., Gilbert,D.J., Bellefroid,E.J., Martial,J.A.,
            Ihle,J.N., Copeland,N.G. and Jenkins,N.A.
  TITLE     Chromosomal location of fifteen unique mouse KRAB-containing zinc
            finger loci
  JOURNAL   Mamm Genome 7 (6), 413-416 (1996)
   PUBMED   8662221
REFERENCE   8  (bases 1 to 3698)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Matera,A.G., Bourguignon,C.,
            Desai,T., Healy,K.C., Bray-Ward,P., Martial,J.A., Ihle,J.N. and
            Ward,D.C.
  TITLE     Emergence of the ZNF91 Kruppel-associated box-containing zinc
            finger gene family in the last common ancestor of anthropoidea
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10757-10761 (1995)
   PUBMED   7479878
REFERENCE   9  (bases 1 to 3698)
  AUTHORS   Lange,R., Christoph,A., Thiesen,H.J., Vopper,G., Johnson,K.R.,
            Lemaire,L., Plomann,M., Cremer,H., Barthels,D. and Heinlein,U.A.
  TITLE     Developmentally regulated mouse gene NK10 encodes a zinc finger
            repressor protein with differential DNA-binding domains
  JOURNAL   DNA Cell Biol 14 (11), 971-981 (1995)
   PUBMED   7576184
REFERENCE   10 (bases 1 to 3698)
  AUTHORS   Ihle,J.N., Smith-White,B., Sisson,B., Parker,D., Blair,D.G.,
            Schultz,A., Kozak,C., Lunsford,R.D., Askew,D., Weinstein,Y. et al.
  TITLE     Activation of the c-H-ras proto-oncogene by retrovirus insertion
            and chromosomal rearrangement in a Moloney leukemia virus-induced
            T-cell leukemia
  JOURNAL   J Virol 63 (7), 2959-2966 (1989)
   PUBMED   2542606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134615.5 and AC164096.3.
            
            On Feb 6, 2019 this sequence version replaced NM_011764.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046298.1, AK032286.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-444               AC134615.5         11098-11541         c
            445-571             AC134615.5         7671-7797           c
            572-667             AC134615.5         7258-7353           c
            668-3617            AC134615.5         6-2955              c
            3618-3698           AC164096.3         129967-130047       c
FEATURES             Location/Qualifiers
     source          1..3698
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.14 cM"
     gene            1..3698
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="zinc finger protein 90"
                     /db_xref="GeneID:22751"
                     /db_xref="MGI:MGI:104786"
     exon            1..444
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /inference="alignment:Splign:2.1.0"
     CDS             412..2322
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     finger protein 90 homolog; zfp-90; zinc finger protein
                     NK10; Nk10 expressed protein; zinc finger protein 83"
                     /codon_start=1
                     /product="zinc finger protein 90 isoform 2"
                     /protein_id="NP_035894.1"
                     /db_xref="CCDS:CCDS22635.1"
                     /db_xref="GeneID:22751"
                     /db_xref="MGI:MGI:104786"
                     /translation="MAPRPPTAKPQESVTFKDVAVNFTQEEWHHVGPAQRSLYRDVML
                     ENYNHLVSLGYQVSKPEVIFKLEQGEEPWISEKEIQRPFCPDWKTRPESSRSPQQGVS
                     EVFLRTNVLSHTTIGDIWNVAIQGHQESGRRHLGPEASSQKKITTLEKKIEQNKVGED
                     SSLSTDLVPQLDISSSIRPSDCKTFGNNLEHNSELVTQSNILAKKKPYKCDKCRKSFI
                     HRSSLNKHEKIHKGDPYSNGTDQGAQSGRKHHECADCGKTFLWRTQLTEHQRIHTGEK
                     PFECNVCGKAFRHSSSLGQHENAHTGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPY
                     RCNLCGRSFRHSTSLTQHEVTHSGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFEC
                     SICGRAFGQSPSLYKHMRIHKRSKPYQSNNFSLAFVPNTPLPQGEGLLTEVKSYHCND
                     CGKDFGHITDFSEHQRLHAGENSYGSEQTLLGQQSLSHPREKPYQCNVCGKAFKRSTS
                     FIEHHRIHTGEKPYECNECGEAFSRLSSLTQHERTHTGEKPYECIDCGKAFSQSSSLI
                     QHERTHTGEKPYECNECGRAFRKKTNLHDHQRTHTGEKPYACKECGRNFSRSSALTKH
                     HRVHARNKLQES"
     exon            445..571
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /inference="alignment:Splign:2.1.0"
     exon            572..667
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /inference="alignment:Splign:2.1.0"
     exon            668..3698
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2460..2465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="hexamer: ATTAAA"
     polyA_site      2484
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="major polyA site"
     regulatory      2559..2564
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="hexamer: AATATA"
     polyA_site      2578
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
     regulatory      3331..3336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="hexamer: AATACA"
     polyA_site      3354
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
     regulatory      3675..3680
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
                     /note="hexamer: AATAAA"
     polyA_site      3698
                     /gene="Zfp90"
                     /gene_synonym="6430515L01Rik; KRAB17; mKIAA1954; NK10;
                     Zfp64; Zfp83"
ORIGIN      
        1 gcagtcgcac tcgtggctct gcgcccgccg ctgtggccat tgtccgaccc tgttgttgca
       61 gagcagtact gccgggaaca agaaactgca gcgggcgcta gaggggcgga cctgaggtcg
      121 cggattccga agccccggag gcagattccg agtgcagtgg gtaggaggct gtcctccggg
      181 cctcgccgac catcctgcgg acggactggg cgtggccgga ggaactgtcc cgaagctgtg
      241 gggcctttca tttggccttg ggaagagcag caggagaagg cggggctcct ccccacgttt
      301 cggccgaagt ggctgcagag ctgaaggggt ggggcctcgg ggtagcccgg tgagtggatc
      361 ctgtcctctc tcctcagccc tggaccatag ccagcacaca ctgaggcagg aatggccccg
      421 agacctccga cggccaagcc ccaggagtcg gtgacattca aagatgtggc tgtgaacttc
      481 acccaggaag aatggcacca cgtgggccct gcccagagga gcttatacag ggatgtcatg
      541 ctggagaact acaaccacct ggtgtcgctc gggtatcaag tctccaagcc agaggtgatc
      601 ttcaaattgg agcaaggaga agagccatgg atatcagaga aagaaatcca aagacctttc
      661 tgtccagact ggaagaccag gcctgagtcc tcacggagtc ctcagcaggg cgtatctgaa
      721 gtattcctca gaacaaatgt tttatcacac accacaatag gtgatatctg gaatgtcgct
      781 atccaggggc atcaggaaag tgggagaaga catctggggc cagaggcatc ttcccagaag
      841 aaaataacca ctctagagaa aaaaattgag caaaacaaag ttggtgaaga ctctagtttg
      901 agcacagact tggttccaca actggacatt tcttcaagta taaggcccag tgactgtaaa
      961 acatttggaa ataatttgga acacaattca gaactagtta ctcagagtaa tatccttgct
     1021 aaaaagaagc cttataagtg tgataaatgt aggaaatcat ttattcatag atcatcactt
     1081 aataaacacg agaagattca taaaggcgat ccttactcca atggtacaga ccaaggagct
     1141 cagtctggaa ggaaacacca tgagtgtgcg gactgtggga aaaccttcct ctggagaaca
     1201 cagctcacgg agcaccagag aattcacact ggggaaaaac cctttgagtg taatgtgtgt
     1261 ggaaaggcct tcaggcacag ctcgtccctt ggtcagcatg aaaacgcaca tacaggagag
     1321 aagccctatc agtgtagcct ctgtgggaaa gccttccagc gcagttcatc tcttgttcaa
     1381 caccagagaa tccacacggg agagaagccc tatcgctgca atctctgtgg gaggtcattc
     1441 aggcacagca cgtccctcac gcaacatgag gtgacccaca gtggggagaa acccttccag
     1501 tgtaaggaat gtgggaaggc ctttagcagg tgttcttccc ttgtccagca tgagaggacc
     1561 catacaggag agaagccttt cgagtgcagc atttgtggga gggcatttgg tcagagccca
     1621 tccctttata aacatatgag gattcataaa agaagcaaac cttaccaaag taacaacttc
     1681 agcctggctt ttgtgcctaa cactcctctt cctcaaggtg aaggcctgct tactgaagta
     1741 aagtcgtacc attgtaatga ctgtgggaaa gacttcggtc acattacaga cttctctgag
     1801 caccagaggc tccacgctgg ggagaattcc tacggctctg aacagaccct tcttggtcag
     1861 cagtccctgt ctcatccccg agagaaaccc tatcagtgca acgtatgtgg gaaagctttt
     1921 aaaaggagta caagttttat agagcatcat cgaattcaca ctggagagaa accctatgaa
     1981 tgtaatgagt gtggggaagc cttcagtcga ctctcgtcac tcacgcaaca cgagaggacc
     2041 cacactggcg agaaacccta tgagtgcatt gactgcggga aagccttcag tcaaagctca
     2101 tccctgattc agcacgaaag gacgcatacc ggagagaaac cctatgagtg taatgagtgt
     2161 gggcgggcct ttagaaagaa gaccaatttg cacgaccatc agagaactca cactggagag
     2221 aaaccctatg cttgcaagga gtgtgggaga aacttcagcc ggagctccgc ccttactaaa
     2281 caccaccgag ttcacgcccg gaataaactg caggaaagct aaacaatggg atggggagga
     2341 ggcacggccg aacatctgct tccaacccag tgtcagagga ttctgaaagt ctgagaatgt
     2401 aattatgtgt ttggacactg tgtatagaga aaactgccac tagaagaaaa aaattttaaa
     2461 ttaaagccat tctttcatac cttattacag gcttcttgta gaactacgta cggcatatgt
     2521 agtcgtttgg aaatgatgtg accttactaa agcttttgaa tatatgtgtg cagagtcacc
     2581 aagttttaac agcttgatat gtaaatcctg ttgttcacaa ccttgaaaga aagaaagaaa
     2641 actcatagta tggccaaggc tcatttcaaa catcattgac agtttcactt gactgaaact
     2701 gtagaaatca gtttgtttcc cagaagtcaa cattcagaga attagagcag ctagaccaac
     2761 cacctaaatg tacagatggt tgcacggcag gctctaaccc acaaagctga acgttgaaag
     2821 cttgttttcg ggttctttgg cctcatacca tggctataga aagggtattt tggagttcag
     2881 aggcctttaa agttttaata tagattccca gacatgttgt gacattttga agagcctgaa
     2941 gacatacagg caaccatatg gaaatctgtc aaaaatgtaa ggccacttag tggaagcttt
     3001 acaaaagaaa agattggcag aaactgacat tgatggaatg ggacaggaac acatgcatgc
     3061 gtgtgcacac acacacacac acccttccca gctgtaatta taccttcaac cgatgtatca
     3121 ttccattggc atttcatggc actgcatgag gagaatttgc agtttgcttg aaaccctgcc
     3181 ctcctctctg gtgcttctga gccccccccc ccccgcccca agtcaatttt actatagaga
     3241 agtatacacc taactaccca cagccataaa ctttctctct gactccattt acggaaacag
     3301 catggtttgc ctctttttgt gtgcaaagag aatacactgc tgtttcaacc cccatcttaa
     3361 ctcagttgct tttctgttat caaaccgtga gaaaagcttc ctcggtgcct tgcaaatgaa
     3421 tgtggagtaa ctgtgaccat tgatcccttt cacacattat cacaaagtcc tccagcctct
     3481 ttccatgagt tccaggaagt gatgttgatt gttgtgagtg aggctaattg gtaagacttt
     3541 cctattagct tttctgctta ctggatgaca agtttcattg acctttctta atctttatgg
     3601 taaggggtgg ctctcaggaa ttcatatatt ttagggtttt ttttgggggg ggcaggtttg
     3661 ttttagtggg gataaataaa tgttcatggg agctgaaa
//
