LOCUS       NM_173387               2427 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 879 (Zfp879), transcript variant
            1, mRNA.
ACCESSION   NM_173387
VERSION     NM_173387.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2427)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2427)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2427)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK036152.1 and BF457823.1.
            
            On Mar 20, 2014 this sequence version replaced NM_173387.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036152.1, BB628900.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2408              AK036152.1         2-2409
            2409-2427           BF457823.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..2427
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 30.93 cM"
     gene            1..2427
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /note="zinc finger protein 879"
                     /db_xref="GeneID:214779"
                     /db_xref="MGI:MGI:3053099"
     exon            1..183
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /inference="alignment:Splign:2.1.0"
     exon            184..248
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..1907
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /note="isoform 1 is encoded by transcript variant 1; novel
                     zinc finger protein"
                     /codon_start=1
                     /product="zinc finger protein 879 isoform 1"
                     /protein_id="NP_775563.1"
                     /db_xref="CCDS:CCDS24638.1"
                     /db_xref="GeneID:214779"
                     /db_xref="MGI:MGI:3053099"
                     /translation="MTTRLLPAQVQEPVTFRDVAVSFSQDEWLHLDPAQRTLYREVML
                     ENYSNLVSLGILFSKPKVIAQLEQAEDFPMVESGMFQGVYLGWKSLFEPIVSKEENKK
                     VLKNQRVDKFFNFILGKTCVNEEQLEEQPGNKKNPFSEMLLSVRRGCRQERGFPGVGL
                     VRNPGIKLPFRRKPGVAAGGGKPHLQQYSVLFKQLGFNRARQLCKCNICGKVFFHSSS
                     LSKHQRTHTGEKLYKCQGCRKAFSQRSSLAQHLRVHTGEKPYLCSDCGKAFSFTTSLI
                     GHQRMHTGERPYECKECGKTFKGSSSLHNHQRIHTGEKPYKCNECGRAFSQCSSLIQH
                     HRIHTGEKPYECSQCGKAFTSISRLSRHHRVHTGEKPFHCNVCGKVFSYHSALTIHQR
                     THTGEKPYACKECGKAFSQSSALTQHQRIHTGEKPYKCAECGKAFSWLSRLNIHHRIH
                     TGEKPYHCKECGKAFSSHSAVNTHRKIHTGEKPYKCSDCEKAFNQSSALIQHQRIHTG
                     EKPFNCKVCGKAFRQSSSLMTHMRIHTGERPYRCEACGKAFSQSSSLANHQKTHY"
     exon            249..375
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /inference="alignment:Splign:2.1.0"
     exon            376..471
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /inference="alignment:Splign:2.1.0"
     exon            472..2412
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2383..2388
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /note="hexamer: ACTAAA"
     polyA_site      2412
                     /gene="Zfp879"
                     /gene_synonym="Znf879"
                     /note="major polyA site"
ORIGIN      
        1 cttacccgct ctgggcattg agctttctgg gttttctggc agagctggaa cggccgggaa
       61 cctgcgggcc agggctgaga gcctggcgga agcacgcaga ggcctcagct gctggtgagg
      121 gcctcgggcc ctgactccag gttctgctgc ccgaacagcg gtcaaagaag cctccggctt
      181 cagggtcttc tcaggaggag ctacagaggg agaaaatgac cacgaggttg ctgccagccc
      241 aggttcagga gcctgtgacg ttcagggatg tggccgtgtc cttcagccag gatgagtggt
      301 tgcacctgga ccctgctcag agaaccttgt accgagaggt gatgctggag aactacagca
      361 acctggtctc gctggggatc ctgttttcca agccaaaggt catcgctcag ttagaacaag
      421 cagaagactt cccgatggtg gaaagtggga tgtttcaagg tgtgtacctc ggatggaaga
      481 gcttgtttga gcccatagtt tccaaagaag aaaataagaa agtcttgaaa aaccagagag
      541 tggataaatt ttttaacttc atattgggaa aaacgtgtgt aaatgaggaa cagttagagg
      601 agcaaccagg caataagaaa aaccctttca gcgagatgct gctttctgtc agaagaggct
      661 gtagacaaga gcgaggcttt ccaggggtcg gactcgtgag aaatcccggc ataaagctcc
      721 catttcgtag gaaacctgga gttgccgccg gagggggaaa gccccactta cagcagtact
      781 cagttctgtt caaacaactg ggattcaacc gagcccgcca gctttgtaaa tgcaacatct
      841 gtgggaaagt cttcttccac agttcctccc tgagcaagca tcagaggact cacactggag
      901 agaagctcta caaatgtcag ggctgtcgga aagctttcag ccaacgctca tccctggcac
      961 agcacctgag agtccatact ggggaaaagc cgtacctctg tagtgactgt gggaaggcct
     1021 tcagcttcac cacctctctc attgggcatc agaggatgca cactggagag agaccctatg
     1081 aatgtaagga atgtggcaag accttcaaag gcagctcctc ccttcataat caccaacgga
     1141 tccacactgg agaaaagcct tataagtgta acgagtgtgg gagagccttt agccagtgct
     1201 catctctgat tcagcaccat aggattcaca ctggggagaa accatatgaa tgcagccagt
     1261 gtgggaaggc ctttacatca atatcacggc tgagcagaca ccaccgcgtc cataccggag
     1321 agaagccctt tcactgtaat gtgtgtggca aagtgttcag ttaccactcg gccttgacca
     1381 tccatcagag aactcacact ggagagaaac catatgcatg caaggaatgt gggaaagcct
     1441 tcagccaaag ctcagcactt acccaacatc aaagaatcca cactggagaa aagccgtaca
     1501 agtgtgccga atgcggaaag gccttttcct ggctctcacg gcttaacatc caccacagga
     1561 tccacacggg ggagaaaccg tatcactgta aagagtgtgg gaaagccttc agttcccact
     1621 ctgcggtcaa tacgcacaga aagatccaca ctggtgagaa accttataaa tgcagtgact
     1681 gtgaaaaagc cttcaatcaa agctcggccc ttattcagca tcagagaatc cacaccggag
     1741 agaagccgtt taactgtaaa gtttgtggga aagccttccg acagagttcc tcgcttatga
     1801 cacatatgag gatccacaca ggagaaaggc cgtacagatg cgaagcttgc gggaaagcgt
     1861 tcagtcagag ctcatctctt gccaaccacc agaagacaca ttactgagaa aaaccataga
     1921 agtaaaatgc atgcatgcgg tagatctgcc ttgagacatt ccttctccgc tgactgtaac
     1981 agaattcatc tggagagtga tgagtagcag ttagtcgggg ctgagcatga agttagattt
     2041 cagcaaacat caggcatttg tgatgcagta taaacttgtg agtgttggga aaacttacat
     2101 agaatatttg gaaatgttac atcgtatgtg gattctttga agtttcactg atggtggagt
     2161 tgacactgag attgaaagat taatattttc tttctagtga tgcagactta atagccacca
     2221 gctttttttt aacatcactg ctgatttagg tagaagtgca tacttgagac cagtctagga
     2281 tctgtgttgt ctgcctttga gtgtgagtgc aaaatagctg aattagaaaa cacgagaaaa
     2341 gaagtctgcg tgggtaacgc acagctgctt cagggtcatt tcactaaagt gtgttttcta
     2401 atactctgga aaaaaaaaaa aaaaaaa
//
