LOCUS       NM_023750               5711 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 84 (Zfp84), mRNA.
ACCESSION   NM_023750 XM_001480149 XM_001480155
VERSION     NM_023750.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5711)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5711)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5711)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   4  (bases 1 to 5711)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 5711)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 5711)
  AUTHORS   Marine,J.C., Gilbert,D.J., Bellefroid,E.J., Martial,J.A.,
            Ihle,J.N., Copeland,N.G. and Jenkins,N.A.
  TITLE     Chromosomal location of fifteen unique mouse KRAB-containing zinc
            finger loci
  JOURNAL   Mamm Genome 7 (6), 413-416 (1996)
   PUBMED   8662221
REFERENCE   7  (bases 1 to 5711)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Matera,A.G., Bourguignon,C.,
            Desai,T., Healy,K.C., Bray-Ward,P., Martial,J.A., Ihle,J.N. and
            Ward,D.C.
  TITLE     Emergence of the ZNF91 Kruppel-associated box-containing zinc
            finger gene family in the last common ancestor of anthropoidea
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10757-10761 (1995)
   PUBMED   7479878
REFERENCE   8  (bases 1 to 5711)
  AUTHORS   Ihle,J.N., Smith-White,B., Sisson,B., Parker,D., Blair,D.G.,
            Schultz,A., Kozak,C., Lunsford,R.D., Askew,D., Weinstein,Y. et al.
  TITLE     Activation of the c-H-ras proto-oncogene by retrovirus insertion
            and chromosomal rearrangement in a Moloney leukemia virus-induced
            T-cell leukemia
  JOURNAL   J Virol 63 (7), 2959-2966 (1989)
   PUBMED   2542606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK145426.1, AK034259.1 and AC122256.3.
            
            On or before Aug 8, 2008 this sequence version replaced
            XM_001480149.1, XM_001480155.1, NM_023750.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083748.1, AK034259.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               AK145426.1         2-107
            107-2149            AK034259.1         2-2044
            2150-5711           AC122256.3         10553-14114         c
FEATURES             Location/Qualifiers
     source          1..5711
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 17.25 cM"
     gene            1..5711
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /note="zinc finger protein 84"
                     /db_xref="GeneID:74352"
                     /db_xref="MGI:MGI:107780"
     exon            1..144
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /inference="alignment:Splign:2.1.0"
     exon            145..209
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..1856
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /note="zinc finger protein 69"
                     /codon_start=1
                     /product="zinc finger protein 84"
                     /protein_id="NP_076239.1"
                     /db_xref="CCDS:CCDS21074.1"
                     /db_xref="GeneID:74352"
                     /db_xref="MGI:MGI:107780"
                     /translation="MAVVDVSTVFKELVVFRDVAVEFCKEEWECLGPEQRSLYRDVML
                     ENYSNFVSLGLAISKPSIISLLEQGKEPWIVEQAGWCPDLLSVNEAKSLSLKNGIFGK
                     ESLKWKIIERVGSSCLEESCFGDDWKCKGLLETKRESTEEYLQGVTDPLEETSARFVQ
                     PAPIALSEVTHSETKLSEQDAGETITQQVRIPTSDKLNEMYENAFIYYTGEMKRQQDF
                     AGDRCDELKACSRGFAYDFQLAPYQINKKPYQCEICGKIFEKHAYLVQHNRFHTGEKP
                     CECKECGKAFTNCSLLVQHQRVHTDEKPYECKHCGKAFLYFSTFFQHQRTHTNEKPYE
                     CHKCQKAFNKSANLTRHQRIHSGEKPYECNLCGKTFTWASNLNDHQKIHTGEKPYECN
                     YCEKAFLCHSAFMKHYRTHTNEKPYECQECMKAFRQKAHLIQHQRVHTGEKPYECKEC
                     GKAFACPSYFNRHQRIHTGERPYECKECGKAFIDCKTLILHQRIHTGEKPFQCQQCSK
                     AFRQRSHLTQHQRIHTGEKPYECKECGQAFTRLLQVKKHQRVHTVGEILCI"
     exon            210..336
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /inference="alignment:Splign:2.1.0"
     exon            337..423
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /inference="alignment:Splign:2.1.0"
     exon            424..5711
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5691..5696
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /note="hexamer: AATATA"
     polyA_site      5711
                     /gene="Zfp84"
                     /gene_synonym="2210410P13Rik; 4633401C23Rik; KRAB18;
                     Zfp69"
                     /note="major polyA site"
ORIGIN      
        1 gctcagccac atggcggaag tggctggaaa gaggttgttc cggatcatct cagtgcccta
       61 cccgacctaa cccggtactg tcctggtcgg tattcgctgg tcgtccgagt tcgaagccgt
      121 gagatcgcag tttatacttt tgaatttgtc cagagtgccc ggaagagctg agaagcatgg
      181 ccgttgtgga cgtcagcacc gtgtttaagg agttggtggt gttcagggac gtggctgtgg
      241 agttctgtaa ggaggagtgg gagtgtctgg gccctgagca gaggtcgcta tacagagatg
      301 tgatgctgga gaactacagc aactttgtgt cgctgggact tgccatttct aagccatcaa
      361 taatttcact gctggagcaa ggcaaagagc cctggatagt ggagcaagca ggatggtgcc
      421 cagatctgct gtctgtaaat gaagctaaga gtttgtctct aaagaatggc atctttggaa
      481 aggaatcgtt aaaatggaaa ataatagaaa gagttggtag ttcttgcctt gaggaatctt
      541 gttttggaga tgattggaaa tgcaagggac tccttgagac aaaacgggaa tctacagagg
      601 aatatttaca gggagtgaca gacccgttgg aagagacgtc agccagattc gttcagcctg
      661 cacccattgc tctgagtgaa gtgacgcatt ccgaaacgaa actctctgag caggacgcag
      721 gcgaaaccat cactcaacag gtgcgaattc ctaccagtga caaacttaat gaaatgtacg
      781 agaatgcctt tatctattac acaggtgaga tgaagcgtca gcaggacttt gctggggaca
      841 gatgtgatga gctaaaggcg tgcagcagag gattcgccta tgactttcag ctcgccccgt
      901 atcagatcaa caagaagccc taccagtgcg agatctgtgg caagatcttt gagaagcacg
      961 cttaccttgt tcagcataac cgctttcaca cgggggagaa accctgcgaa tgtaaggagt
     1021 gcgggaaagc cttcaccaac tgctcgctgc tcgtccagca ccagagggtc cacacggacg
     1081 agaagcccta cgagtgcaag cactgtggga aggccttcct ctacttctcc acgttttttc
     1141 agcatcagag aacccacacc aacgagaagc catacgaatg ccacaaatgt cagaaggcct
     1201 ttaacaagag tgccaacctc actagacatc aaaggatcca cagcggcgag aaaccctacg
     1261 agtgtaactt atgcggaaag accttcactt gggcttccaa cctgaatgat caccaaaaga
     1321 ttcacaccgg cgaaaaacct tacgagtgta actactgcga aaaggccttt ctctgccatt
     1381 cggccttcat gaaacactat agaactcaca caaacgagaa gccctacgag tgccaggagt
     1441 gtatgaaggc cttccggcag aaagcccatc tcatccagca tcagcgagtc cacactggcg
     1501 aaaaacctta cgaatgtaag gagtgtggga aggccttcgc gtgtccttcc tactttaaca
     1561 gacaccagag gattcacact ggagagaggc cttatgagtg taaagagtgt gggaaggctt
     1621 tcattgattg taaaactctc attctgcacc agaggatcca cactggcgag aagcccttcc
     1681 agtgccagca gtgtagcaag gccttcaggc agaggtccca cctgacgcag catcagagga
     1741 tccacactgg cgagaagccc tacgagtgta aggagtgcgg gcaggccttc actcggctct
     1801 tacaggtgaa gaaacaccag agagtccaca cggtggggga aatcctgtgt atctgaacac
     1861 tgccctctat ttactgaaaa tccctgactc agcatcttca caaccacaca gaagataaac
     1921 attaatgact cggaaatgcg ggaaacacct ttatgtgtcc ctcagctatg cagactgctg
     1981 gaaaagcctt ctggaaggga agggtgtgaa acaacctctc agactgtgct tcacgttgtg
     2041 caatttatac tatgctcaaa ataggaagct ctccttattt tcggctattc gttatggaat
     2101 agagtttgtc agagagaacc atctgatgac tattctattt tttttttttg ctttcttctt
     2161 ttttgttttt tgtttttttg ctttataacc tactgtttat tgagtattaa ttcacatagg
     2221 aaaaataaaa attaaattat gaatagaaat actaattcta ttaccagtag aagggttcta
     2281 tttaagtata gttatagaca gtaccacata gagaacaatg gtgtgcatgc tgttagtgta
     2341 ggggtttcac atgcatcgat tgctgactgt gttttattaa gttgacttca gccctgcttc
     2401 agattgctgc cttttagctg ggaggatggt tattttgggg acgggatgaa tcagtaaatg
     2461 gggtctttgg catagctgct agacaggatc aggaaggatt cggaaccgtc ctcttatgat
     2521 gttctttgtt actatttttg gaacattcat acccacttta ttcatgacat cgcctgtcag
     2581 tgcttgtccc atgccaaagc cttcaaaagg agttccggcg tgacagtgat tggaacggaa
     2641 cacgagcaga tttccacttc gacttgagtt gagtctgaaa gccgacccta gcaaggccac
     2701 atggactcac tgctcagggt gcccggcaca gcagaggaca gtcggatctg tgcaggacaa
     2761 gaattggaac aaactcataa tctgtcaccg tcaccaggtg actctcagtc atgtgaaaag
     2821 tgcagtctga aaatacagct tgcttcagtg tggaagaaca acagctctac acactaaagc
     2881 ctggcgtggt tcatttgaat agatgttgtc aaattacaca ccttcccccc cccccccaaa
     2941 gagcaataaa tcttagagtt gacagcagaa ttacacatta tatacaataa tcaatgaatt
     3001 taaagaagtt tctaaaaacc atcaataaaa tggataaccg gactttagga gctttttcca
     3061 aatctgatac atagactagg ttttcggggg cctagaggga catttgaaag acacaagcac
     3121 aaccgtcaga gctaatggga agtagagcat tcccaggcag aagtatgttt gttcggttgg
     3181 ctttggtggg ttttatttta agacatggtc tttcttaaac ttgtggcaat cctcctgctt
     3241 gaacctactg agtgctggga ttagaagtgt gagctaccac actggcttga acttggagcc
     3301 ttgagcctgc tcagcttggc tctgccctag agccttttat tcccggctct ctttgttctg
     3361 aggcaggcag ggtcttggct aaatggccta ggcaggcttt ggtgccctta cattaagcct
     3421 ctcaaatagc tggggctata gacctctgtt accaggtaca gacagaaagt ttgactgcta
     3481 taaaataagg tattctccag atttcaaaat caggcagcaa gcaaaggcag tgaacatgga
     3541 atttgccagt gggaaattgt gtggtagaat ggtcaacata aattgtatca gtaactccaa
     3601 taaccttttg aataggctga ttgctgtagt tgaaaggaag tgttttttaa ttttttaaac
     3661 agattttttt tcttcaaagg tttatttatt atatgtaagc acactgtagc tgtcttcaga
     3721 cacaccagaa gaaggcatcc gatttcatta cagatgtttg tgagccacca tgtggtttct
     3781 gggatgtgaa ctcaggacct cctgaagagc agtcagtgct cttaaccgct gaaccatctc
     3841 tccagccccc ccccccccga aaggaagctt tttttctcat ttaaatggaa tactaggttg
     3901 gtgtgggtca tatctgaaat tatccctggc aaggaacgat attgctgtgg cttcagatta
     3961 gcctgaggtc cataggacag ccccagctta aaagtgggaa agggaagaca gacaatgctg
     4021 cagaaagatc aaaactgagg gacgggggaa gcccgtgctg ttgagatact aaccaaagga
     4081 gttcaagaag aaacaacaaa aaactggttt accaaaaaat tagggaaaaa agaacataat
     4141 gtgtgaagat tcgttaaaag ggtcaggatg cttttatttg tatgtaacca gcagcatggg
     4201 ctccataaag aaaaagcaaa agttaatcag aactacaaag aaaaaagcca gcttggactt
     4261 taacatggct gtcaggcaaa atcaggacag cacatttgaa caaagaccat tgaaaagtct
     4321 aacacacaca tggcctctcg caaacttaca gaatactctt ttatataaga atttatttcc
     4381 tgtgtcttaa acttcaagtc tgaatcagta tcagtcagtt ctaatttatc taatgcattc
     4441 ttacctaggc ctagagatgt cgctccatat attttgaaat atcttaaata tccttgaaac
     4501 aaccattagt taaagaaaac ttaatggagc tgaggaggaa gtggtagttt gtggtatgca
     4561 gtcgtgtgta gcggacaggg tttccaggaa acaggtcccg tgaggaattc attgtctcaa
     4621 gatgatagag cattttaaaa ggtggaagca aatgtaacac gttaggaatt tagtgggaag
     4681 caaaagttga tacaagtttt taaacagttg acatattctg ggataatctt tcgctgttaa
     4741 gaaggaatta ctgacgtggg tagtgatgtc tctcacatct ttaatcctag cagaggctag
     4801 atgatttctg agttccaggc cagtctggtc tacatagtga gaccctgtct gggggggggg
     4861 gggggaataa aagtggaggc tgtggggatc acaaggcata gttcctaagg cctgcattcc
     4921 agcactcagg agtgtaggcc ctgagcagcc tgggctacat aatgagactc cttctcaaca
     4981 ctgaaactga atcctacaca ttattgaaga atgagccctt tagcacttct acgtgtagga
     5041 agtggaacat gttagaaaat aaagactaat gccctcattc atagttcttg tctgtctagt
     5101 ggggtttttg gccttaacca cagttagttg aatcgaacgc tttctgaggt atgtagaccc
     5161 ttttctccct tgcgatagag aacgaggtga tgatctttgt acatattagc ttctatctgc
     5221 agatatctat taaaggttca tccctgggtt ggagttgcta ctttctagta tatgtacatt
     5281 tacaaaaggc caatgttact agcttttggt tctttctcca atgttacata gtgcccctat
     5341 ccaatcattt ttctgacact tttttgtttg ttaaagcttt gatttcgcta gtctgttagg
     5401 taaaaagtgt tatgacagtt taatttgcat ttttcctgct gtatgtaact tgcatctaat
     5461 gccatatttt cctattttca aatattacat tttctgtgga gtgtctcagt accattttct
     5521 gttgaatgat tgctttcctg atggctatgt aagacttata atcctctcga actgtgttta
     5581 taccagtttt ctctttttta tgcctggttt ggatttgtag acttaagcaa ttcatgattg
     5641 gaaggtatct gtcttggtgt taatgcttgt aaatcatttt cccccattcc aatatatttt
     5701 ccaaaatccc a
//
