LOCUS       NM_025884               3278 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 830 (Zfp830), mRNA.
ACCESSION   NM_025884 XM_972625
VERSION     NM_025884.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3278)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3278)
  AUTHORS   Kafer,G.R. and Cesare,A.J.
  TITLE     A Survey of Essential Genome Stability Genes Reveals That
            Replication Stress Mitigation Is Critical for Peri-Implantation
            Embryogenesis
  JOURNAL   Front Cell Dev Biol 8, 416 (2020)
   PUBMED   32548123
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3278)
  AUTHORS   Vandormael-Pournin,S., Guigon,C.J., Ishaq,M., Coudouel,N., Ave,P.,
            Huerre,M., Magre,S., Cohen-Tannoudji,J. and Cohen-Tannoudji,M.
  TITLE     Oocyte-specific inactivation of Omcg1 leads to DNA damage and
            c-Abl/TAp63-dependent oocyte death associated with dramatic
            remodeling of ovarian somatic cells
  JOURNAL   Cell Death Differ 22 (1), 108-117 (2015)
   PUBMED   25168238
  REMARK    GeneRIF: Oocyte-specific inactivation of Omcg1 leads to DNA damage
            and c-Abl/TAp63-dependent oocyte death associated with dramatic
            remodeling of ovarian somatic cells.
REFERENCE   4  (bases 1 to 3278)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3278)
  AUTHORS   Leguillier,T., Vandormael-Pournin,S., Artus,J., Houlard,M.,
            Picard,C., Bernex,F., Robine,S. and Cohen-Tannoudji,M.
  TITLE     Omcg1 is critically required for mitosis in rapidly dividing mouse
            intestinal progenitors and embryonic stem cells
  JOURNAL   Biol Open 1 (7), 648-657 (2012)
   PUBMED   23213458
REFERENCE   6  (bases 1 to 3278)
  AUTHORS   Houlard,M., Artus,J., Leguillier,T., Vandormael-Pournin,S. and
            Cohen-Tannoudji,M.
  TITLE     DNA-RNA hybrids contribute to the replication dependent genomic
            instability induced by Omcg1 deficiency
  JOURNAL   Cell Cycle 10 (1), 108-117 (2011)
   PUBMED   21191184
  REMARK    GeneRIF: Omcg1 plays a role in the tight coupling between mRNA
            pathways and maintenance of genome integrity during cell cycle
            progression.
REFERENCE   7  (bases 1 to 3278)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   8  (bases 1 to 3278)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   9  (bases 1 to 3278)
  AUTHORS   Artus,J., Vandormael-Pournin,S., Frodin,M., Nacerddine,K.,
            Babinet,C. and Cohen-Tannoudji,M.
  TITLE     Impaired mitotic progression and preimplantation lethality in mice
            lacking OMCG1, a new evolutionarily conserved nuclear protein
  JOURNAL   Mol Cell Biol 25 (14), 6289-6302 (2005)
   PUBMED   15988037
  REMARK    GeneRIF: Omcg1 disruption results in the lengthening of M phase and
            it is an important regulator of the cell cycle in the
            preimplantation embryo.
            GeneRIF: Phenotype of knock-out mice suggests that Omcg1 (Ccdc16)
            is a key regulator of the cell cycle in the preimplantation mouse
            embryo
REFERENCE   10 (bases 1 to 3278)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK132497.1.
            
            On Apr 6, 2007 this sequence version replaced NM_025884.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK132497.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3278              AK132497.1         2-3279
FEATURES             Location/Qualifiers
     source          1..3278
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 50.22 cM"
     gene            1..3278
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="zinc finger protein 830"
                     /db_xref="GeneID:66983"
                     /db_xref="MGI:MGI:1914233"
     exon            1..3278
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1119
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="coiled-coil domain containing 16; coiled-coil
                     domain-containing protein 16"
                     /codon_start=1
                     /product="zinc finger protein 830"
                     /protein_id="NP_080160.2"
                     /db_xref="CCDS:CCDS25146.1"
                     /db_xref="GeneID:66983"
                     /db_xref="MGI:MGI:1914233"
                     /translation="MASSTSTRTPAGKRVVNQEELRRLMREKQRLSTNRKRIESPFAK
                     YNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGATQGPSTGTVPQATK
                     RRATDVESQDAKKAKASAGPQVQPSTSASSANLDAARAAPSKPGLGLLPDYDDEEEEE
                     EEGGGEERRDSSKHLPDAQGKEHSLASPRETTSNVLPNDPFNTNPPKAPLVPHSGSIE
                     KAEIHEKVVERRENTAEALPEGFFDDPEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVN
                     TISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEVLTIKELQK
                     KEEENVDSDDEGELQDLLSQDWRVKGALL"
     regulatory      1283..1288
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="hexamer: TATAAA"
     polyA_site      1303
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="major polyA site"
     regulatory      1566..1571
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="hexamer: CATAAA"
     polyA_site      1588
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="major polyA site"
     regulatory      2507..2512
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="hexamer: AATAAA"
     polyA_site      2540
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
     regulatory      3020..3025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
                     /note="hexamer: AATAAT"
     polyA_site      3041
                     /gene="Zfp830"
                     /gene_synonym="2410003C20Rik; Ccdc16; Omcg1; Znf830"
ORIGIN      
        1 agactcgcct gagtcctggg cgcaaacatg gcgtcctcca cctctactcg gactccggct
       61 gggaagcgag tggtgaatca ggaagaactg aggcgcttga tgagggagaa gcagcgcctg
      121 agcaccaacc ggaagaggat cgaatctcca ttcgccaagt acaaccgtct ggggcagctg
      181 agctgcgcac tgtgtaacac cccggtcaag agcgagctcc tgtggcagac ccatgttctg
      241 ggaaagcagc accgggagag agtagcggag ctgaaaggcg ccaaaggagc aacccagggc
      301 ccgtcgaccg gcactgtacc tcaggccacc aagaggagag cgacggatgt ggagagccaa
      361 gacgccaaga aagccaaggc ctccgcggga cctcaggtac agccctccac ctcagcctcg
      421 tccgccaact tggatgccgc tagggcggcc cccagtaaac ctggactcgg tttactgcct
      481 gattatgacg atgaggaaga ggaggaagaa gagggaggtg gagaagaaag aagggacagc
      541 agcaagcatc ttccggatgc acagggcaaa gaacactcgc ttgcctctcc gagggagaca
      601 acaagcaatg tgctgccaaa cgatccgttt aatacaaatc ctcccaaggc ccccttagtt
      661 cctcattcag ggtccattga gaaagcagaa atacatgaaa aagtggtgga aagaagagag
      721 aacaccgccg aagcattacc agaagggttc ttcgacgacc ctgaggtaga tgcaaaggtc
      781 cggaaggtgg atgccccaaa ggatcagatg gacaaagagt gggacgagtt tcaaaaggct
      841 atgaggcaag tcaacactat ctctgaagcg atcgttgctg aagaggatga ggagggacgg
      901 ttggaccggc agattggaga gattgatgag cagatagaat gttaccgccg agtggaaaag
      961 ctgcggaatc gccaggatga aataaaaaac aaacttaaag aggttttgac cataaaagaa
     1021 cttcagaaaa aggaagagga gaatgtggac agtgacgacg aaggagaatt acaggatttg
     1081 ctgtctcagg actggagggt aaagggggct ttgctgtaag gttttgaaga cccaagcttt
     1141 ccatcagtcc ccgctgtccc ttaaaaagtg ctgtgtccaa gttcttgggt tcctctgacc
     1201 ttggataccc ctaattgttg ggataaagta agccagtgag gagtaatact ttggggatgg
     1261 tactgtgtgc ggtgctattt attataaaat gtttgaggta aaaccgtttt tgacattttt
     1321 gaaattataa ccacaaattg ccaacttttt catctttaca ggttcaatgt ggtttttcag
     1381 ttgtaaaatc taagttgtaa atattgcaca tagctaagta tatatttata taagtcactc
     1441 tgttttgatc cttatattag tcagataaaa aagacacatg tttatatgac ctcgatgtat
     1501 atatattttc aagccttaaa ctccaagggt tggcgctttg ggaaggttgt ttttagaagg
     1561 ccactcataa acacatattc ttcataaagc agtggatggg tattcttttt tcaaaagcat
     1621 acagatgtcc agactccagc acagtgtttc ttttgacaag atcaatgatt gctaagttgt
     1681 acatcagtat cacctgtgaa acttttgatt gttcatggaa tgtcaaatcg cctatgaagc
     1741 tttagtgcct gagccccatc ttaaagaggt tttgaccata aaagattcca taaattaaat
     1801 gggatccaga tgacaatatt cttgactatt cccaggttat tctagtattt gcccaggttg
     1861 gagattcagc tgccttaagt gtaaaaccta tctatatatt tttcaggctt tgttttcctt
     1921 gaacatgctc tgtagtttac tgtactccct gcccccgagt gctgctaaac agatcagagc
     1981 tatgggaatg ctaggcaagt attctcccac caccaagcca gttttcaaat gaaggaaata
     2041 ttaccccatt gagttggaaa ttttattttt gtggtaaatc aggcttgtgt ttacaggttc
     2101 tttcaatggc aggaagatag gtaagttgct agtaaggcaa tgccagttac cttattctag
     2161 ttattgatat tttaaagttt tccttgcttt ggaggatgag tgttttatat acagcatctt
     2221 ccaatttact ataatagcta agacatactg ttctaagcct aggccagtca ggattctaag
     2281 cactttacat atattaaccc attctagctc aggttttata aggaaaacca ccaagaagaa
     2341 aaggcctgaa agccttgaaa actggatgtg gtgcctcacc cctgacattg cagcttttgg
     2401 aaggctgagg gagatgcagc ctggactatg tagtgagacc ttgtctaaaa taaaaaaaaa
     2461 aaaaaatcct ttaattctaa agaactgttt ttacaggcaa tgtggaaata aatggaggat
     2521 ttgggttttt ttaaactgaa gaagtctgtg acaattcggt gttattctag ttgtagtgtg
     2581 tggtatggaa gaagtctagg acaaggaact gggaaattat gtacacaaca cttcaaaagt
     2641 taagcgactg attagttatg gactaagagg gtgggaataa caatttctca ggaagagcta
     2701 acatttagta actagaagta gaagaaaaaa atgtagaagg gacaggaata ggaatgtcaa
     2761 aggacttttt ttttttttaa tgatttattt aaatatgcat tggtgtttta cttacatgta
     2821 tgtctgtgga agggtgtcag atcctctgga acttacacgc cattgtgagc tgccatatgg
     2881 atgctggaat tgaacccgga tcctctggaa gagcaatcag tgctctttaa ccactgaagc
     2941 atatctccag cccaggattt tcttttaggt atgaatacca agaagacatt gtctgacttg
     3001 gtatgtgcca cacatgatta ataatcttgc tccttatgac acaaagtctg aattcttttt
     3061 ttttttttgg ttttttgaga gggtttctct gtgtagccct ggctgtcctg gaactcactc
     3121 tgtagaccag gctggcctgg aactcagaaa ttcacctgcc tctgcctccc aagtgctggg
     3181 atcaaaggtg tgcgccacca tgcccggcta caaagtctga attcttaact gtcaactatt
     3241 agctatttca gtttgaaaat tacaaaaagt gcgccacc
//
