LOCUS       NM_001419348            6332 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 780B (Zfp780b), transcript variant
            5, mRNA.
ACCESSION   NM_001419348 XM_030242703
VERSION     NM_001419348.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6332)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139063.11.
            
            On Mar 30, 2023 this sequence version replaced XM_030242703.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.178931.1,
                                           SRR12282455.38116907.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                AC139063.11        192841-192921       c
            82-318              AC139063.11        190491-190727       c
            319-371             AC139063.11        188504-188556       c
            372-498             AC139063.11        187470-187596       c
            499-597             AC139063.11        185374-185472       c
            598-6332            AC139063.11        172886-178620       c
FEATURES             Location/Qualifiers
     source          1..6332
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 15.97 cM"
     gene            1..6332
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="zinc finger protein 780B"
                     /db_xref="GeneID:338354"
                     /db_xref="MGI:MGI:2444764"
     exon            1..81
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            82..318
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            319..371
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             339..2759
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="isoform 1 is encoded by transcript variant 5"
                     /codon_start=1
                     /product="zinc finger protein 780B isoform 1"
                     /protein_id="NP_001406277.1"
                     /db_xref="GeneID:338354"
                     /db_xref="MGI:MGI:2444764"
                     /translation="MANSNSQDMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRDMML
                     ETYSNLVAVVGRCISKPDLIVLLEQEKEPWMAVKEETDRPSPDLETDYDAENISPENP
                     INNKKFLKQSIKQLITFDPKDSSTSIGPNYSTFHGLQDCQSDAGQQITNKEGVPPHTC
                     QTLAHNTEKPYECKECGKCFGCRSTLTQHQSIHTGEKPYECEECGKAFRLPQQLTRHQ
                     KSHSGEKPFECNECGKAFHLPDLLKYHKTIHTGEKPFECRECGKSFNRVSNLVAHRII
                     HADVKPYKCSECGKAFKRRSNLVQHQKTHSDERPFQCKDCGKGFIVLAQLTRHQNIHT
                     GEKSFECHECGKAFRLPQQLTRHQKSHSGEKPFKCNECGKAFHLPDLLKYHKTIHTST
                     KPFECRECGKSFHRISNLVEHRLIHADVKPHKCNECGKAFKRSKSLMQHQKIHSGERP
                     FQCQECGKAFIVLTHLTRHQTIHTGEKSFECNECGKKFRTATHLVMHQTIHTGEKPFE
                     CNVCGKAFRLQVYLSEHQKIHIEEKPFKCKLCGSAFRRKYQLNEHYTIHTDEKPYQCK
                     ECGKCFRQRSNFTEHQSIHTGNKPFECKECGKFFRLNTLLIRHQKSHSSERPYKCKEC
                     GKAFHLPSELNNHQIVHTSNRPFECKVCGKSFKRESTLIQHSVIHGGVKSYECNECGK
                     AFIHRSSLFHHRKIHSDEKPFKCQECGKAFVVLAYLTRHQSIHTGEKSFECQQCGSAF
                     RYKSQLSKHQRSHTDVKLFQCMEGGNDFVHGTNLSIHQGIHTSENPFQCNEYGEAFKY
                     HYQFPWTF"
     exon            372..498
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            499..597
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            598..6332
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3825..3830
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3843
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="major polyA site"
     regulatory      6204..6209
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      6232
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
     regulatory      6306..6311
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      6332
                     /gene="Zfp780b"
                     /gene_synonym="B230208L21Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggtgtcgtgt atcgctccct tgaaaagtca ggtttttctc gtaggtggaa gaaatcgctc
       61 tatggcctac gtcctcacag atctttacaa actattaatc acagtcacca tgtctcatgg
      121 tgcatctctg gacttctgct gcgtagctga agtgttgtcg tctctatatg atcagcatct
      181 tcccaactct tccttatggt tcttcgtctc tcccaccacc acagtgctgc acatccaacc
      241 tctgccattc aaaccgcatt gtccagcgtt tcactgttcc aatgagacga cagggtcaga
      301 tcccacgtga gtgacagtga gaggaagcct gaagaagaat ggccaactct aattctcaag
      361 acatggtctg tgggtcagtg acatttaggg atgtggctgt tgacttctct caggaggagt
      421 gggcctgcct ggatgctact cagaaggtct tatacaggga catgatgttg gagacctaca
      481 gcaacctggt cgcagtggtg ggacgttgca tttccaagcc agatctgatc gtcttactag
      541 agcaggagaa agagccctgg atggctgtga aggaagaaac agacaggccg agcccagact
      601 tggagacaga ttatgatgct gaaaatatat ctccagaaaa tcctattaat aataaaaaat
      661 tcctcaaaca gagcataaag caattaataa cttttgaccc taaggactct agtactagta
      721 ttggccccaa ctatagtaca ttccatggac tacaggattg tcagagtgat gctggtcaac
      781 agattactaa caaggaagga gtgcctcctc acacctgcca gactcttgct cacaatacag
      841 aaaaaccata tgaatgtaaa gagtgtggga agtgctttgg ttgtaggtca actcttactc
      901 agcatcagag tattcatact ggagagaagc cctatgaatg tgaggagtgt gggaaggcct
      961 tcagactccc ccaacagctc acaaggcatc agaagtctca cagtggtgag aaacctttcg
     1021 agtgtaatga atgtggaaag gcttttcatc ttcctgacct gctcaagtac cataaaacca
     1081 ttcatacagg tgaaaaacca tttgaatgca gggaatgtgg gaagtccttc aaccgtgtct
     1141 ccaaccttgt tgcacatagg attatccatg ctgatgtgaa accatacaaa tgtagtgagt
     1201 gtgggaaagc ctttaagcgt cgctcaaacc tcgtgcaaca tcagaaaact cattctgatg
     1261 agagaccctt tcagtgtaag gactgtggga agggcttcat tgttctggct cagctcacaa
     1321 ggcaccagaa cattcacact ggagagaagt catttgaatg tcatgaatgt gggaaggcct
     1381 tcagactccc ccaacagctc acaagacatc agaagtctca cagtggtgag aaacctttca
     1441 aatgtaatga atgtggaaag gcttttcatc ttcctgacct gctcaagtac cataaaacca
     1501 ttcatacaag tacaaaacca tttgaatgca gggaatgtgg gaagtccttc catcgcatct
     1561 ctaaccttgt tgaacatagg cttattcatg ctgatgtgaa accacacaag tgtaatgagt
     1621 gtgggaaagc ctttaaaaga agcaaaagcc tcatgcaaca tcagaaaatc cattctggtg
     1681 agagaccctt tcagtgccag gagtgtggga aggccttcat tgttctgact catctcactc
     1741 ggcaccagac cattcatact ggagagaagt catttgaatg taacgaatgt ggcaagaaat
     1801 tcagaactgc cacacacctt gttatgcacc agactattca cactggtgag aaaccctttg
     1861 aatgcaatgt atgtgggaag gcttttcggc ttcaggtata cctttctgag catcagaaaa
     1921 ttcacattga agaaaaaccc ttcaagtgta agctctgtgg gtcagccttc agacgtaagt
     1981 accaacttaa tgaacattac acaattcaca ctgatgagaa accctatcag tgcaaggaat
     2041 gtggcaaatg ctttcgtcaa agatcaaatt ttactgaaca tcagagtatt cacactggaa
     2101 acaaaccctt tgagtgtaaa gaatgtggga agttctttag actcaataca cttctcattc
     2161 gtcatcagaa atctcacagt agtgagagac cttataagtg taaagaatgt ggaaaggctt
     2221 tccatcttcc cagtgaactt aataaccatc aaattgtcca tacaagtaac agaccctttg
     2281 agtgcaaggt atgtgggaag tccttcaagc gtgaatccac tctcattcaa catagtgtta
     2341 ttcatggtgg tgtgaaatca tatgaatgta atgagtgtgg gaaagctttt attcatcgct
     2401 caagcctgtt ccaccatcgg aaaattcatt ctgatgagaa accgtttaag tgtcaggagt
     2461 gtggaaaggc cttcgttgtt ctggcgtacc tcactcggca ccagagcatc cacactggag
     2521 agaaatcatt tgaatgtcag cagtgtgggt cagccttcag atacaagtcc caactcagta
     2581 aacatcagag aagtcatact gatgtgaaac tctttcagtg catggaaggt ggaaatgact
     2641 ttgtccacgg aacgaacctt agtattcatc agggaatcca taccagtgag aatccctttc
     2701 aatgtaatga atatggggaa gcttttaaat accattacca gtttccttgg acgttttaga
     2761 atccatattg ataagaatcc tcatgaatgt agtgaatgtg ggaagtactt tacacatggc
     2821 agagatgtta aagtacatca aagcattcac actggtgaca aactcacagt gttaagaacg
     2881 tgggaagact tagttgaata tgaaacttgt tttgacatta tacatacatt aataagaagt
     2941 catgatgtaa ggaaaatgaa aggcctacag taaattctaa gctagcgagc tgtatatcag
     3001 agaatttcta ctgatgagaa attctatgaa tatgagtaag gtggcaaaat gttaagattt
     3061 agttcagcct tcatgcacag tggcaagttc atatcggtaa tcaaccctat cgctgtaaag
     3121 aatgtgccaa gagctctaat tggaacttag atcttcaaaa tcaaggaagc catgctggct
     3181 tcaaatacag tgaatacaag gaatgtgggg acatttatag aattagctgt taaagctcat
     3241 cagagagtcc ctgtaggtct gaaatcctgt gacgatgaag actcaggaaa agcctttatt
     3301 gcaaatgggt gagcttatac agcctgagaa aatccatact ctccaggagg cctgcgagtg
     3361 taggcaagga ggacaagcca gtggatgaaa atgtgactgg acaccagaga actcatattg
     3421 ggaaggttgt gacttaaaag aatgtgggaa ctttaatctg tcctgggaat tggtcaacat
     3481 caaaagaatt catgtactgt tgctgccaag aaaccctttg gaatgggtat gtggaaagtc
     3541 ggttgttcag agaagatact ctgttgcgaa tgtcttttat tgtcagaaat acaatgtagt
     3601 aatcatgatt tactctcatc ttgctagttg tataaactta actcactcat tagtcaccaa
     3661 gggctgtcaa ctaaggggga gcagttactg caactgtgtt tgccggagat gctccccacc
     3721 ccccatggtt cctgagatgg tggagcacat gtttactttt tgcataattt gttaatggcc
     3781 agcacaggac cagccaaagt tatggcaaca gagttataat agaaaataaa gtccttgaca
     3841 atattggtca gtgcccatgt tctataatac agcttttaca tagttctagt ttcatgagca
     3901 ttagcataac tgacatggaa gcctgattgc actgtagata gtttaggaaa gtctcatgct
     3961 tttacccact gttaagtttt aaataacttt attctgaata cttgtaatgg atggttagga
     4021 acttgaaagt atttgaattg tgagtccatt tcttaagtat ttgtgtgtaa agttttaaaa
     4081 caatcattga tgaataagaa ctttctaaaa agagtaaaaa ctataaaaag ttcaaaagtt
     4141 aaaatcctat tatttgtgcc ctctccacac atgaagataa actatatttg tgataggaca
     4201 agaaagtttt tggatcttca atctctctct ctctctctct ctctcttttt tttttttttt
     4261 tttttttttt tttttggttt tttgagacag ggtttctttg tatagccctg gctgtcctgg
     4321 aactcacttt gtagaccagg ctggcctcga actcagaagt ccgcctgcct ctgcctccgg
     4381 agtgctggga ttaaaggcgt gtacatcctc gcccagccaa tctcttattt ctgagaacat
     4441 tttaacttca actagaattt gattccctcg atggagaatc tcatggtata tccaattcta
     4501 ctagaggtca aattgcctct gataatttat tgtgacttct ttttaaacct cccactccag
     4561 ctatctgttt atcttcatac tattaaactg cctgcttggg caaaagctcc ccctgcagct
     4621 gctgagcaag ataatagaat gtgggtttgt tctaaatgct tgggattata ctccggtccc
     4681 aaatacctga atgtactcag agctggctgg aataaagcct ttcatttggc tctacactgt
     4741 gtctgagtgg gcatctctag tgagcaacct gtaacacctt tacaaaatag ccagagtgaa
     4801 actacttata aaaaaatata tgtgtgttgt ggccagtcag cagctcgcaa cgaacggttc
     4861 tactgagatg gcaactcggg ctgaaagaga agaactagac gggcggaaga aagaacgaag
     4921 ccaagtcaaa agtctgatca aagctccatt tttactgttg caacactcag ttatgaagga
     4981 agggggaggg gacccgattc ccgccaaata atctcggatc cagtagcagg gtgagcacgt
     5041 gatggcttca gaacagcaag gcggcaggtt ctagcagtgg gcatggcaga acgaatgagc
     5101 aggaagctcc accccagaac aagcaggttt caggctgggg gaggggagac tacatatgtg
     5161 caatttttca tccatgttga aagcttggaa tattcaatac acatctgtat cctcacctag
     5221 attgaaaatt gtcaacaatt tacaaggttg atcctgtttt tctgtgtata taggtttggg
     5281 gatgcaccat taatatgttt tagaactgaa tatggcaaag catatctgaa tcctagttat
     5341 tataaagatg aattaggaga atcaagagtt ggaggcaagg ggctggagag atggctcagt
     5401 agttaagagc actgactgct cttccagagg tcatgagttc aattcccagg aaccacattg
     5461 tggctcacag ccatctgtaa tgggatctga tgctctattc tggtgtgtct gatgatatct
     5521 actcacataa ataaataaat aaataaaaaa caaataaata aataaatctt aattaaaaag
     5581 agttggaggc aagcctagct atataatgac tttaagtcca gttaaggcat tatagagacc
     5641 cctatattta aaaaaaaaaa aaagacacga cattttatct gttactaacc agccgagatg
     5701 gaatgccatc tataccatag agtcataaat gttcttaaga ctgagaattt tatggcatgc
     5761 agaagtttgt aattttcctc caaactttac tgatttaaac tgcatatatc ctgaggagac
     5821 tccagtatag ataaacattt ggccttgctc tgtgctttat taaattttca gtgttgattt
     5881 aacctggagc tttgtaagca tagtagggat gctctcaacc aaccagctgc attcacaatc
     5941 cttgggtatt gtatcttcta cccaagggag attagtttca gatgaaacat tttgagtaag
     6001 aacacattgt aggttgtatg tcctgttgta acatgtccaa agacatgtat gtgtccgcta
     6061 tcacattact gatgaaatta agtttcattt ggataagatg gcagtgccag agctctgtta
     6121 aaaggtctac tttggagtaa tctatgtggg gaaactatta cttccaagca tagatatgtg
     6181 tagtttactc ttggttaaat ataaataaag attgaaatca actttaaatg gatatcgaaa
     6241 taatgcatgg tgtaacttga atgccataat tcgaattgtg tggtgtaact gatgttgtac
     6301 tcaatattaa actccccttc tttcttggtt ta
//
