LOCUS       NM_178763               3254 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus zinc finger protein 750 (Zfp750), mRNA.
ACCESSION   NM_178763
VERSION     NM_178763.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3254)
  AUTHORS   Schwartz,B., Levi,H., Menon,G., Maria,R., Upcher,A., Kotlovski,Y.,
            Oss-Ronen,L. and Cohen,I.
  TITLE     ZNF750 Regulates Skin Barrier Function by Driving Cornified
            Envelope and Lipid Processing Pathways
  JOURNAL   J Invest Dermatol 144 (2), 296-306 (2024)
   PUBMED   37660780
  REMARK    GeneRIF: ZNF750 Regulates Skin Barrier Function by Driving
            Cornified Envelope and Lipid Processing Pathways.
REFERENCE   2  (bases 1 to 3254)
  AUTHORS   Butera,A., Agostini,M., Cassandri,M., De Nicola,F., Fanciulli,M.,
            D'Ambrosio,L., Falasca,L., Nardacci,R., Wang,L., Piacentini,M.,
            Knight,R.A., Jia,W., Sun,Q., Shi,Y., Wang,Y., Candi,E. and
            Melino,G.
  TITLE     ZFP750 affects the cutaneous barrier through regulating lipid
            metabolism
  JOURNAL   Sci Adv 9 (17), eadg5423 (2023)
   PUBMED   37115925
  REMARK    GeneRIF: ZFP750 affects the cutaneous barrier through regulating
            lipid metabolism.
REFERENCE   3  (bases 1 to 3254)
  AUTHORS   Ye,Q., Bhojwani,A. and Hu,J.K.
  TITLE     Understanding the development of oral epithelial organs through
            single cell transcriptomic analysis
  JOURNAL   Development 149 (16) (2022)
   PUBMED   35831953
REFERENCE   4  (bases 1 to 3254)
  AUTHORS   Seishima,R., Leung,C., Yada,S., Murad,K.B.A., Tan,L.T.,
            Hajamohideen,A., Tan,S.H., Itoh,H., Murakami,K., Ishida,Y.,
            Nakamizo,S., Yoshikawa,Y., Wong,E. and Barker,N.
  TITLE     Neonatal Wnt-dependent Lgr5 positive stem cells are essential for
            uterine gland development
  JOURNAL   Nat Commun 10 (1), 5378 (2019)
   PUBMED   31772170
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3254)
  AUTHORS   Wikramanayake,T.C., Borda,L.J., Kirsner,R.S., Wang,Y., Duffort,S.,
            Reyes-Capo,A., Barsam,A., Urbieta,M. and Perez,V.L.
  TITLE     Loss of MPZL3 function causes seborrhoeic dermatitis-like phenotype
            in mice
  JOURNAL   Exp Dermatol 26 (8), 736-738 (2017)
   PUBMED   27488654
  REMARK    GeneRIF: ZNF750/MPZL3 pathway plays a critical role in the
            pathogenesis of seborrheic dermatitis
REFERENCE   6  (bases 1 to 3254)
  AUTHORS   Richardson,R., Mitchell,K., Hammond,N.L., Mollo,M.R.,
            Kouwenhoven,E.N., Wyatt,N.D., Donaldson,I.J., Zeef,L., Burgis,T.,
            Blance,R., van Heeringen,S.J., Stunnenberg,H.G., Zhou,H.,
            Missero,C., Romano,R.A., Sinha,S., Dixon,M.J. and Dixon,J.
  TITLE     p63 exerts spatio-temporal control of palatal epithelial cell fate
            to prevent cleft palate
  JOURNAL   PLoS Genet 13 (6), e1006828 (2017)
   PUBMED   28604778
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3254)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   8  (bases 1 to 3254)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CA555996.1, AK037185.1 and CF586141.1.
            
            On Jul 15, 2009 this sequence version replaced NM_178763.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK140792.1, AK037185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-40                CA555996.1         1-40
            41-3204             AK037185.1         2-3165
            3205-3254           CF586141.1         213-262
FEATURES             Location/Qualifiers
     source          1..3254
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 85.49 cM"
     gene            1..3254
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="zinc finger protein 750"
                     /db_xref="GeneID:319530"
                     /db_xref="MGI:MGI:2442210"
     exon            1..113
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /inference="alignment:Splign:2.1.0"
     exon            114..1719
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /inference="alignment:Splign:2.1.0"
     CDS             299..2410
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="protein ZNF750"
                     /codon_start=1
                     /product="zinc finger protein 750"
                     /protein_id="NP_848878.1"
                     /db_xref="CCDS:CCDS25779.1"
                     /db_xref="GeneID:319530"
                     /db_xref="MGI:MGI:2442210"
                     /translation="MSLLKERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHM
                     KYGLCKNSITLVSEQDRIPKCPKSSSLDPKQTHQPEPTSKPATSKSLLNGLSSFDPKS
                     QQGSAKEDAKENLEMQARGAHKGPQKPALQKEMAPEAILSTQPCLDSGVRHSAFVPVG
                     EHRLRGPEDTEATEVLANSTTKASSFHAKSAFHTPGYPWKAGSPFLPPDFPHKISSTK
                     GFGAISPYMHPAIPEYPHPFYAEHGLAAIYSPYLLTGNTPECETTLLSVYGTQDQRHF
                     LSPAGPIPKHLNTSPSTYDHYRFFQQYHSNLPIPYGFYRPESAFPSYSLRLPSVTGIT
                     RDQSSRLLEDATLAYPASSPSELNLSSSHRKHTECEKGSPVPEAKDPSKDGQRDAEEA
                     KMSPRAGSAATGSPGRPSPTNFTQTSQTFEGLCDLSNKAASSGTLERLQQAEQSPTAF
                     KPVQRGSESPHSQPPANRTESPKSLQAMNGDPPAQTGSSNSFITEAPPSSPEDHSRIG
                     PLNLSKKLETNPAATYGPMYASNAQADTLQDLPLNLSVKDLCNAWAPRPALPGPPQGA
                     EPAATPKTETKGSEDRTSRVETPQDKAHSRTTPDVHTEDSSDEQKQTAAVALCQLAAY
                     SPGNVRVADEEGTVQEPTRQDVPTLSATENLEAQCDLRPKGQKRTSQRDTGKSQQGTK
                     KPKLNDPVPRVLTLRRRTRVS"
     exon            1720..3243
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2981
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="major polyA site"
     regulatory      3187..3192
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="hexamer: AATAAA"
     regulatory      3221..3226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="hexamer: AACAAA"
     polyA_site      3226
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
                     /note="major polyA site"
     polyA_site      3243
                     /gene="Zfp750"
                     /gene_synonym="A030007D23Rik; Znf750"
ORIGIN      
        1 gccggctcca gtttcaccga gccagcgagc cagcgtgaga acagatcctg ctcctcagac
       61 ctcagcacct tgcacagaag aaggactccg catcccagca ctgcccacct ttgctgcagg
      121 tgcctgacgg aaggaactct cctggttagg ccctcagcac atggagctgg cttcaaatag
      181 agtactcaca gcaagaaaga agacagtact cacctcctcc aaagccacca cattctggtc
      241 aaagaggagg cagcagtgac cacacaccga gcagaccaga gtccaaacac aaaggataat
      301 gagtctccta aaggaacgga aaccaaaaaa gccacactat attccacggc ccccaggaaa
      361 gcccttcaag tacaaatgct tccagtgtcc ttttacatgt aacgagaagt cacatctttt
      421 caatcacatg aagtacggtc tctgtaaaaa ctccattact ttagtgtcag agcaagatcg
      481 tattcccaag tgtcccaaat ctagctcgct ggatcctaag cagactcacc agccagagcc
      541 cacctcaaag ccagccactt ccaaatctct cctaaatgga ctctccagct ttgatccaaa
      601 gtctcaacag ggctctgcaa aggaggatgc caaagagaac ctagaaatgc aggctcgggg
      661 agcccacaaa ggtccccaga aaccagccct acagaaagaa atggcaccag aagccattct
      721 cagcacccag ccctgcctcg acagtggggt tagacattca gcatttgttc cagttgggga
      781 acacagactt agggggccag aagatacaga ggccactgaa gtgctggcca actctaccac
      841 caaagcctcc tcattccatg ccaagtctgc attccacacg cccggttacc cctggaaagc
      901 tggctcccca ttcctccctc ctgactttcc acataaaatc tcctctacaa aggggtttgg
      961 tgccatctcc ccctatatgc atcctgcaat cccggagtac ccccatccct tctacgcaga
     1021 gcatgggctg gctgccatct actcccccta cctcctgact gggaacacgc ctgagtgtga
     1081 gaccactttg ctgtctgtct atgggaccca agaccaaaga cacttcctgt ctcctgctgg
     1141 gccaattccc aagcacttga acacatcccc atcaacatat gaccactaca gatttttcca
     1201 gcagtaccac tctaatctgc cgatccctta tgggttttac agaccagagt ctgcatttcc
     1261 ctcctacagt ctcaggctcc catctgtcac tggcatcacc cgagatcaga gctctcgctt
     1321 gcttgaagat gcaaccctgg cttacccagc ctcaagtccc tcagagttaa acctttcaag
     1381 ctcccacagg aaacacacag agtgtgagaa gggaagtcca gttcctgagg ctaaagatcc
     1441 ttctaaagat gggcaaaggg atgcagaaga agccaaaatg agcccccgag cagggagcgc
     1501 tgccacgggc tccccgggga ggccaagccc caccaacttc acccaaacaa gccaaacatt
     1561 cgaaggcctg tgtgacctct caaacaaagc agcctcctcc ggaaccctag agcgactcca
     1621 gcaagctgag cagagcccca ccgccttcaa acctgtccaa aggggttcag aaagccctca
     1681 ctctcaacct cctgcaaaca gaacagagtc tccaaaaagc cttcaggcca tgaatggtga
     1741 ccctccggcc cagacaggga gcagtaactc tttcatcaca gaggccccac cctccagccc
     1801 agaggaccac tccagaatag gtcccctcaa tctctctaag aagctggaga caaaccctgc
     1861 agccacgtat ggacccatgt atgcaagcaa cgcccaggca gacactctgc aagacctgcc
     1921 actcaatctg tccgtgaagg atctctgcaa cgcctgggct ccaaggcccg ccctcccagg
     1981 cccaccccaa ggtgcagaac ccgctgccac tccaaagact gagacaaagg gttctgaaga
     2041 taggacaagc cgcgtggaga caccgcaaga caaggcccac agcaggacaa ccccagacgt
     2101 gcacacggag gacagcagtg atgaacagaa gcagacggca gctgtagctc tctgtcagct
     2161 ggcggcctac agcccaggga acgtccgagt ggccgatgag gaaggcacag tccaggaacc
     2221 cacccgtcag gatgtgccca ccctcagtgc tacagagaac ctggaggctc agtgtgacct
     2281 cagacccaaa ggacaaaaga ggacaagtca aagggacaca ggaaaatccc agcaaggaac
     2341 taaaaagcca aagctgaatg accccgtccc aagagtgctt actctccgca gaagaacccg
     2401 ggtatcctga ggcctcaagt gcactcagtg ctatggctag agagaggctt ttcacactac
     2461 gtgccaggca gcaacttcac ttttttgctt tttggaggag gtactgtctt gccatgttgc
     2521 tcaggctggc gttaaacttg tgatcttcct gccttggcct cctaagtgct gggccagcca
     2581 gtgttcccac agtttacctt cactttttat caagtcagtt tttataaata caatttttct
     2641 tctctcctca aaaaggacaa aaggctgtaa tctttagttt tttttgtaaa cattaagata
     2701 aatattaaaa ggtgtttcta cttctggttg ttaaaaaaaa aaatctgagt ggcttatact
     2761 ctccaagacg gatgacttac actgggactt catgtttgtg acacaccagg gaaatacaca
     2821 gaactagctc agcaatgtga gtagactcac agaaaggacc ttaaacaagt actatttttc
     2881 aaaactaaaa cttttaccgt gttgttgtgt tactattaaa tatagctatg tgttttgatg
     2941 ccagaaacat cttcagttta aatatcaact gttacacgta agaagtgttg tgattatttc
     3001 taactgaacc gtccacaaac atctagaggc tgactttaag ttactttaga gtaacttatt
     3061 tccatcaggg aagtgcttgc tggtcaaggt ttgatcacct tattctattt gcttatgatg
     3121 tcaaagcaaa ctttctcact taggctcact ttccactccc taaaatgatg tacctgttaa
     3181 tttcccaata aactcatgtg tgaactttga gaacacataa aacaaagatc aatatcagct
     3241 ctaaaaaaaa aaaa
//
