LOCUS       NM_178384               3919 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus zinc finger protein 74 (Zfp74), mRNA.
ACCESSION   NM_178384 XM_993809
VERSION     NM_178384.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3919)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3919)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3919)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 3919)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   5  (bases 1 to 3919)
  AUTHORS   Agata,Y., Matsuda,E. and Shimizu,A.
  TITLE     Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc
            finger proteins by degenerate PCR
  JOURNAL   Gene 213 (1-2), 55-64 (1998)
   PUBMED   9630514
REFERENCE   6  (bases 1 to 3919)
  AUTHORS   Marine,J.C., Gilbert,D.J., Bellefroid,E.J., Martial,J.A.,
            Ihle,J.N., Copeland,N.G. and Jenkins,N.A.
  TITLE     Chromosomal location of fifteen unique mouse KRAB-containing zinc
            finger loci
  JOURNAL   Mamm Genome 7 (6), 413-416 (1996)
   PUBMED   8662221
REFERENCE   7  (bases 1 to 3919)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Matera,A.G., Bourguignon,C.,
            Desai,T., Healy,K.C., Bray-Ward,P., Martial,J.A., Ihle,J.N. and
            Ward,D.C.
  TITLE     Emergence of the ZNF91 Kruppel-associated box-containing zinc
            finger gene family in the last common ancestor of anthropoidea
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10757-10761 (1995)
   PUBMED   7479878
REFERENCE   8  (bases 1 to 3919)
  AUTHORS   Ihle,J.N., Smith-White,B., Sisson,B., Parker,D., Blair,D.G.,
            Schultz,A., Kozak,C., Lunsford,R.D., Askew,D., Weinstein,Y. et al.
  TITLE     Activation of the c-H-ras proto-oncogene by retrovirus insertion
            and chromosomal rearrangement in a Moloney leukemia virus-induced
            T-cell leukemia
  JOURNAL   J Virol 63 (7), 2959-2966 (1989)
   PUBMED   2542606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149283.2.
            
            On Nov 10, 2017 this sequence version replaced NM_178384.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.25766.1,
                                           SRR7974084.19508.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-211               AC149283.2         122411-122621
            212-388             AC149283.2         124586-124762
            389-443             AC149283.2         132931-132985
            444-570             AC149283.2         138408-138534
            571-666             AC149283.2         138781-138876
            667-3919            AC149283.2         140433-143685
FEATURES             Location/Qualifiers
     source          1..3919
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 17.26 cM"
     gene            1..3919
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /note="zinc finger protein 74"
                     /db_xref="GeneID:72723"
                     /db_xref="MGI:MGI:107784"
     exon            1..211
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
     exon            212..388
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
     exon            389..443
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
     CDS             429..2468
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /codon_start=1
                     /product="zinc finger protein 569"
                     /protein_id="NP_848471.2"
                     /db_xref="CCDS:CCDS39874.1"
                     /db_xref="GeneID:72723"
                     /db_xref="MGI:MGI:107784"
                     /translation="MTESEGLVTFKDVAIDFTQEEWKQLDPTQRNLYRNVMLENYNNL
                     ITVGPPLTKPEVIFKLEQEEEPCVVEREVLWRPCPGEILGIDEHQKIQDGQVFEGIVV
                     TSEASECPEEFASTFFPNADSIPSMHSLFECDGVGECLEPNFGDDDVQYPLPEEQFEY
                     DDAMQPFHTSSPHFVLTPFKCNHCGKGFSQTLDLIRHLRVHTGGKLYECHQCGKGFSH
                     KEKLINHHKLHSREQCYECSECGKTFIKMSNLIRHQRIHTGEKPYVCQECGKSFGQKS
                     NLIDHEKIHTGEKPYKCNECGKSFSQKQSLVAHQKVHTGEKPYACNECGKAFPRVASL
                     ALHMRGHTGEKPYKCDKCGKAFSQFSMLIIHVRVHTGEKPYECGECGKAFSQSSALTV
                     HIRSHTGEKPYECKECRKSFSHKKNFITHQKIHTREKPYGCNECGKAFIQMSNLVRHQ
                     RIHTGEKPYLCKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKV
                     HTGEKPYDCNKCGKAFSQIASLTLHLRSHTGEKPYECEKCGKAFSQCSLLNLHMRSHT
                     GEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRGHTGE
                     KPFDCSNCGKAFSQISSLTLHMRKHTGEKPYVCIECGKAFSQKSHLVRHQRIHTH"
     exon            444..570
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
     exon            571..666
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
     exon            667..3919
                     /gene="Zfp74"
                     /gene_synonym="2810054M15Rik; KRAB8; mszf21; mszf77;
                     zfp-74; Zfp66; Znf569"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttgcaagt tgcaccccca ggctgtgaat gccaggccgc ggggtagccg ctgctacaaa
       61 acccgcccag gctcaagccg gtccccctgc cgcagcgccg cgcccttacc cgagccttgg
      121 ccactctcct gactcgcacg ccgaaggcca gacccgcccg gcgagccgcg cggccctctg
      181 ggaagtgcta ccctgcgcct agcggaccca gctctcattt tcagagttct tcctgcgctg
      241 aggagccttt tataaactca atatttattg aatgttggac atatatcagt caattgttgg
      301 tgtgtgggat atagcagcga acaaaagaag cagtgacccc cccccctctc atgatgctta
      361 cattgccgag gaccagataa taaacaaatt cagcttgctc aggacctccc ccctaaaaag
      421 aagaggaaat gaccgagtct gagggactag tgacgttcaa agacgtggcc attgatttta
      481 cccaagaaga atggaagcaa ctggatccta ctcagcggaa cctatatagg aatgtgatgc
      541 tagaaaacta caacaactta atcacagtag gcccgccact caccaaacct gaagtgattt
      601 tcaagttgga gcaagaggaa gagccttgtg tggtggagag agaagtgctg tggagaccct
      661 gtccagggga gattttggga attgacgagc accagaaaat ccaggacgga caagttttcg
      721 agggaatagt ggtgacgagt gaagccagcg aatgtccgga ggaatttgca agtacgtttt
      781 tcccaaacgc agactccatt ccttccatgc acagtctctt tgaatgtgac ggtgttggag
      841 agtgtttaga gcccaatttt ggtgatgatg atgtacaata cccgttgcca gaggaacagt
      901 ttgaatatga cgatgctatg cagccatttc acaccagctc gccccatttt gtgctgaccc
      961 cctttaagtg caaccattgt ggaaaaggct ttagtcagac cctggacctc atcagacacc
     1021 tgagagttca cacagggggg aagctctatg aatgccacca gtgtgggaaa ggctttagcc
     1081 acaaggagaa gctgatcaac catcataagc tccatagcag ggagcagtgt tacgagtgta
     1141 gcgagtgcgg gaagactttc atcaagatgt caaatctcat tagacatcaa aggatccaca
     1201 ctggggagaa gccgtatgtg tgccaggaat gtgggaaatc cttcggccag aagtccaatc
     1261 tcattgatca cgaaaaaatt cacactggag agaagcctta caaatgtaac gaatgtggaa
     1321 aatccttcag ccagaaacaa agccttgtcg cacatcagaa agttcacact ggggagaagc
     1381 cttacgcgtg caacgagtgt gggaaagcct tccctcgcgt ggcttccctt gctctgcata
     1441 tgaggggcca cacaggggag aagccataca agtgtgataa gtgtgggaaa gccttctctc
     1501 agttttccat gctcatcata cacgtgaggg tccacaccgg ggagaagcct tatgagtgtg
     1561 gtgagtgtgg caaggccttc tctcagagct cggcactgac agtacacatt agaagccaca
     1621 cgggcgagaa accctacgaa tgtaaggaat gcagaaaatc cttcagtcat aagaaaaact
     1681 tcatcaccca ccagaaaatc catactcgag agaaacctta cggatgcaat gagtgtggga
     1741 aagcttttat ccagatgtca aaccttgtca ggcaccagag gatccacacg ggagaaaaac
     1801 cttatctatg taaggagtgt ggcaaagcct tcagccagaa gtcaaatctc attgctcatg
     1861 aaaaaattca ctctggagag aaaccctacg agtgtaatga gtgtgggaaa gccttcagcc
     1921 agaagcaaaa cttcatcacc catcagaaag ttcatacggg agagaaacct tacgattgta
     1981 ataaatgtgg gaaagccttt tcccagatcg cttccctcac gcttcatctg cgaagtcaca
     2041 cgggagaaaa gccttacgag tgtgagaagt gtgggaaggc cttctcccag tgctcactac
     2101 tcaacttaca catgagaagc cacacagggg agaagccgta cgtgtgtaac gagtgcggaa
     2161 aagccttctc tcaaagaacg tccctcatcg tgcatatgag aggccatacc ggcgagaagc
     2221 cctatgaatg taacaagtgt gggaaagctt tctcccagag ttcctccctc actatccaca
     2281 tccggggtca cacgggcgag aagcccttcg actgcagcaa ctgtgggaaa gccttctctc
     2341 agatctcttc tcttacgctt cacatgagga aacacacagg cgagaagccc tatgtctgta
     2401 ttgagtgtgg aaaagctttc agccaaaagt cacaccttgt cagacaccag agaatccaca
     2461 ctcactagag acgccgtgac cacggtgaat gtgaggactg cctcccattg aagtgaacac
     2521 ctcatagcac gcgacacaat cagttctggc gctgactgta ggagagcctt gggaaggtcc
     2581 catgcatctg ttagacaatt cccacttcgg ggaccaattg tatgagaaac tgtcaccaaa
     2641 cacccagtga tatcagtatt ctctttcaag tctgaaagaa aatatctact gtcaatcaac
     2701 gaactcgagc tccttgctga tgtattaagc aagagaagga gattggaaaa accaaaaaca
     2761 ataactttta taggcaatat gagactatgg ggaagtaggt tttgaatgat aatgtatgtg
     2821 tcgggaagaa agtctaaggt aattaggtga catgcgtacg aagttacaaa acgtgctgac
     2881 gaatgcaaaa gaccacttga taaagcaagt tagaaagtta taaaagttca cgaacccttc
     2941 ccagtctctc ccttgtccat acttccactc aaaatttaca catcagttat aaaggatttc
     3001 atgaactgat ttcagagtaa tacggcaagg gaaaggacca caaatagcaa aaacaaaaaa
     3061 tacagcaaaa aacaaaacaa caacaaaaaa cagtttttaa caaaacaact agggaagatg
     3121 ttcactctct actagattat aattatttaa agtttttctt atttaaactc ttttgagtga
     3181 ataaactttt ggaaacaaat tgaaacccaa gacttggcaa ttttctatct gcctggtgct
     3241 actgaaatca ttggaataag tctagcctgt tcaatatgtg tacaggttat gtgaccaaac
     3301 ttgttacttc ttaaacaaag atatacagat tccctcaggc tggtgagacg gccccactga
     3361 taggggtttg ctgccaagct tcacagctga ctacgatacc cagaatccac atggtgggtg
     3421 gaaagaacca acttctacac ttgtcctctg acctccaatg gcacgccatg gtatgcatgt
     3481 acacacacac acacacacac acacacacac acacacactc aaaataggaa aggtaaaatt
     3541 ctaaaatgct ggaaataaag tgaaacatgt tgctttagcg taagaatatt aaaaaaaata
     3601 ataaaccctg caaacatgga atagtctatt ttcttttagt gtactggact cagaagtatc
     3661 catgtatgtc tgcaaagatc tatctataaa tgttcccaga tttgtggctt ggtttgctct
     3721 aagtgatatg taacattatc attaatgcag aggtggatca atatgtttat ttctatgata
     3781 ggacactatt ctttatttaa aagatacaaa attcacatgt agttacatgg ctggatcatg
     3841 atattttgag aggaaacccc aaaatattca attaaccatg gtataatatt tgtaagttaa
     3901 taaaacagtt caaagaaca
//
