LOCUS       NM_001358816            2966 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 7 (Zfp7), transcript variant 1,
            mRNA.
ACCESSION   NM_001358816 XM_006520795
VERSION     NM_001358816.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2966)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2966)
  AUTHORS   Taib,S., Lamande,N., Martin,S., Coulpier,F., Topilko,P. and
            Brunet,I.
  TITLE     Myelinating Schwann cells and Netrin-1 control intra-nervous
            vascularization of the developing mouse sciatic nerve
  JOURNAL   Elife 11, e64773 (2022)
   PUBMED   35019839
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2966)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2966)
  AUTHORS   Memic,F., Knoflach,V., Morarach,K., Sadler,R., Laranjeira,C.,
            Hjerling-Leffler,J., Sundstrom,E., Pachnis,V. and Marklund,U.
  TITLE     Transcription and Signaling Regulators in Developing Neuronal
            Subtypes of Mouse and Human Enteric Nervous System
  JOURNAL   Gastroenterology 154 (3), 624-636 (2018)
   PUBMED   29031500
REFERENCE   5  (bases 1 to 2966)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (bases 1 to 2966)
  AUTHORS   Agata,Y., Matsuda,E. and Shimizu,A.
  TITLE     Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc
            finger proteins by degenerate PCR
  JOURNAL   Gene 213 (1-2), 55-64 (1998)
   PUBMED   9630514
REFERENCE   7  (bases 1 to 2966)
  AUTHORS   Marine,J.C., Gilbert,D.J., Bellefroid,E.J., Martial,J.A.,
            Ihle,J.N., Copeland,N.G. and Jenkins,N.A.
  TITLE     Chromosomal location of fifteen unique mouse KRAB-containing zinc
            finger loci
  JOURNAL   Mamm Genome 7 (6), 413-416 (1996)
   PUBMED   8662221
REFERENCE   8  (bases 1 to 2966)
  AUTHORS   Bellefroid,E.J., Marine,J.C., Matera,A.G., Bourguignon,C.,
            Desai,T., Healy,K.C., Bray-Ward,P., Martial,J.A., Ihle,J.N. and
            Ward,D.C.
  TITLE     Emergence of the ZNF91 Kruppel-associated box-containing zinc
            finger gene family in the last common ancestor of anthropoidea
  JOURNAL   Proc Natl Acad Sci U S A 92 (23), 10757-10761 (1995)
   PUBMED   7479878
REFERENCE   9  (bases 1 to 2966)
  AUTHORS   Ihle,J.N., Smith-White,B., Sisson,B., Parker,D., Blair,D.G.,
            Schultz,A., Kozak,C., Lunsford,R.D., Askew,D., Weinstein,Y. et al.
  TITLE     Activation of the c-H-ras proto-oncogene by retrovirus insertion
            and chromosomal rearrangement in a Moloney leukemia virus-induced
            T-cell leukemia
  JOURNAL   J Virol 63 (7), 2959-2966 (1989)
   PUBMED   2542606
REFERENCE   10 (bases 1 to 2966)
  AUTHORS   Chavrier,P., Lemaire,P., Revelant,O., Bravo,R. and Charnay,P.
  TITLE     Characterization of a mouse multigene family that encodes zinc
            finger structures
  JOURNAL   Mol Cell Biol 8 (3), 1319-1326 (1988)
   PUBMED   2452975
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157554.7.
            
            On Feb 1, 2022 this sequence version replaced NM_001358816.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript. Both variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144887.1, SRR7345562.3745526.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-289               AC157554.7         157403-157691       c
            290-333             AC157554.7         156218-156261       c
            334-460             AC157554.7         155762-155888       c
            461-577             AC157554.7         148653-148769       c
            578-2966            AC157554.7         144605-146993       c
FEATURES             Location/Qualifiers
     source          1..2966
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 36.28 cM"
     gene            1..2966
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /note="zinc finger protein 7"
                     /db_xref="GeneID:223669"
                     /db_xref="MGI:MGI:99208"
     exon            1..289
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            290..333
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /inference="alignment:Splign:2.1.0"
     CDS             331..2388
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 86, related sequence 1"
                     /codon_start=1
                     /product="zinc finger protein 7 isoform 1"
                     /protein_id="NP_001345745.1"
                     /db_xref="CCDS:CCDS37124.1"
                     /db_xref="GeneID:223669"
                     /db_xref="MGI:MGI:99208"
                     /translation="MEAVTFGDVAVHFSREEWQCLDSGQRALYKEVMLENHSSVAGLA
                     GFLVFKPELISRLEQGQEPWVLDLQGAEGTEAPRICQTDSAIRTDRKQTCEYTSLLQR
                     QIPGFGDNLDSKVWSENCPRSLGLSVSGSLFQKHRLNSEAVMPKNSTKDAVQERKELQ
                     ATDVGYRPDDQRDHLSSKLIRRQSVPTGENRYPCEECGKAFRWRSRLNQHKLSHTGEK
                     SYQCNKCTKVFASSSRLIRHQRAHTGEKPFKCDQCGKRFVLASVLTQHQRIHTGERPF
                     KCAECGKGFHLSAKLVQHQRIHTGEKPYRCEECGKTFGQSSSLVHHQRIHTGERPFIC
                     QECGKAFCQRSQLSRHRRTHTGERPYSCQECGKAFCQRATLAQHQKMMHTAEKSQMPR
                     ASESPSLIACQGNTTEEKPFKCEQCGKAFRWLSRLNQHQVVHSGEKPYQCNKCSKAFG
                     CTSRLIRHQRTHTGEKPFKCDECGKRFVQSSHLIQHQRIHTGEKPYVCDDCGRAFTQS
                     SSLIYHQRIHKGEKPYKCSQCGKAFSMSTQLTSHQRTHTGERPYTCNECGKTFRQNST
                     LFQHQIIHVRVKPYECNECGKAFSRSSYLIEHQRIHTRAQGGHEFGDTPESPTVLNHK
                     KVHTVKKLYQCDDCDKVFRWRSYLIIHQRIHTGERPYKCNACGKAFHQIAKLTQHQKL
                     HMR"
     exon            334..460
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            461..577
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /inference="alignment:Splign:2.1.0"
     exon            578..2966
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2943..2948
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /note="hexamer: AATAAA"
     polyA_site      2966
                     /gene="Zfp7"
                     /gene_synonym="KRAB20; KRAB7; Krox-2; mszf73-2; Zfp-7;
                     Zfp65; Zfp80; Zfp86-rs1"
                     /note="major polyA site"
ORIGIN      
        1 ctttccggtg gctctcttgt tgggatccac cacgcgccgg ggcaggtgag taggcgcagt
       61 cgctttcctt gtttttaggg caagggacac ttggctttta ctccccaaaa ggatggaagg
      121 cgtgggcggc tcggtgctgt tgtgaatgcc tggccgaaga cgtgatccca gcggagtaga
      181 atagccgagc atcccagctc ttctagcctg ctcccgggct ccagtgttga acctgagcaa
      241 ggctgcttcc ctccaggcct ggggctgggt gcaacctccc tcattcctcg tgtctgactc
      301 aggacaagcg gatcccaccc tccagatctc atggaggcgg tgacctttgg cgacgtggct
      361 gtgcacttct ctcgagagga gtggcagtgt ctggattctg gtcagagggc cctctacaag
      421 gaggtgatgc tggagaacca cagcagcgtg gcaggactag caggattcct ggtctttaag
      481 ccggaattga tctcccggct ggagcaagga caagagccgt gggtccttga tctacaggga
      541 gcagagggga cagaggcacc aaggatttgc cagacagact ccgctattag aactgatcgc
      601 aagcagacct gtgagtacac gagcctcctc caaaggcaga ttcctggctt tggagacaat
      661 ttggattcta aggtctggtc agagaattgc ccaagaagcc ttgggctaag cgtgagtggc
      721 tcacttttcc agaagcaccg tttgaatagc gaggccgtga tgcccaagaa ctccacaaag
      781 gatgctgtcc aagaacgtaa ggagctgcag gccaccgatg tgggttatcg gcctgatgac
      841 cagagagacc acctgagctc aaaactgatt cggcgtcaaa gcgttcctac cggagagaac
      901 cgttacccat gtgaagagtg tggcaaagct ttcaggtggc gctctcgcct gaatcagcac
      961 aaactgagcc acactggaga gaaatcttat cagtgcaata agtgtacaaa agtcttcgct
     1021 tctagctcgc gactgattcg ccatcagaga gctcacaccg gagaaaagcc gtttaaatgt
     1081 gaccagtgtg ggaagcgctt cgtcctggcc tcggtactca ctcagcatca gaggatccac
     1141 accggagaga ggccatttaa atgtgccgag tgcgggaaag gtttccacct gagcgcaaag
     1201 ctggttcagc atcaaagaat tcatactgga gagaagcctt accgatgtga ggagtgtggg
     1261 aaaacctttg gtcagagctc aagccttgtc catcatcaga gaatccacac cggagagagg
     1321 cccttcattt gtcaagagtg cgggaaagcc ttctgccagc gctcacagct cagcagacac
     1381 cggaggacgc acactggaga gaggccctac tcctgccagg agtgtggcaa ggccttctgc
     1441 cagagagcaa ctctagccca gcatcagaag atgatgcata cagcggagaa atctcaaatg
     1501 ccgagagcct cagagagccc aagccttatt gcctgtcagg gaaataccac tgaagagaag
     1561 ccatttaagt gtgagcagtg tggcaaagct ttcaggtggc tctctcgcct gaatcagcac
     1621 caggtggtcc attctggaga gaaaccttac cagtgcaaca agtgctcgaa agcctttggc
     1681 tgtacctcac gactgattcg ccaccagaga actcacaccg gagaaaagcc ctttaaatgt
     1741 gacgaatgtg gcaagcgctt cgtccagagc tcacacctta ttcagcatca gcgaatccac
     1801 acgggagaga agccttacgt gtgtgatgac tgtgggagag cttttaccca gagctccagc
     1861 ctcatttacc accagaggat ccataaggga gagaagccat ataaatgcag ccagtgtggc
     1921 aaagccttca gcatgagcac acagctcacc agccatcaga ggactcacac cggggagaga
     1981 ccttatacgt gtaacgagtg tgggaagacc ttccgtcaaa actcaaccct tttccaacac
     2041 cagataattc atgttagagt aaagccctat gagtgtaatg agtgtggaaa ggccttcagc
     2101 cggagctcat accttattga acaccagaga atacacacta gagcccaggg gggccatgaa
     2161 tttggggaca cccctgaaag tcccaccgtt ttgaaccata aaaaagtgca cactgtaaaa
     2221 aagttgtacc agtgtgacga ctgcgataag gtcttcaggt ggcgttcgta cctgattatc
     2281 caccagcgga ttcacacagg agagaggcct tataaatgta atgcctgtgg caaggctttt
     2341 catcagatcg caaagctcac tcagcaccaa aaacttcaca tgagataaat catttcccta
     2401 aatgtcttgg ttacttctct cttggctgtg atggcaccat gagtgaccaa ggcagcttag
     2461 acaagagttc tcgtggggct tacagtggag cgttagtttc agagattgtt cacggcagtc
     2521 ttggcaggga gcagggcggc aggaaggcct gatgttagag cagtcgctta gagctcacat
     2581 cgtgagacag ccagttacta ggcagagaga tctaactgga aatggtgaga ggttttaaaa
     2641 aacctcaaag ctggcctccc agttacctcc tctaaagagg gcatacctcc taataattgc
     2701 caaacagttc caccaactga ggaccacatg ttggaacata tgagcccctg gaatttgttc
     2761 tcatccaaac caccacacta aaagtaatgt aactatgaat aagccagaag ccttatttaa
     2821 tttgggtaat ttatgctatc agagacttga ggatgctagg aagattcaga tttgttctta
     2881 aagaatagtc tacttaggaa atgttttatt cgtttctgta atattttacc atttacccat
     2941 taaataaaag tgtgtgtcac actaaa
//
