LOCUS       NM_001008549            3381 bp    mRNA    linear   ROD 07-JAN-2025
DEFINITION  Mus musculus zinc finger protein 175 (Zfp175), mRNA.
ACCESSION   NM_001008549 XM_358669
VERSION     NM_001008549.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3381)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3381)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154108.3.
            
            On Dec 20, 2007 this sequence version replaced NM_001008549.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK155078.1, SRR7652917.454454.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-52                AC154108.3         82481-82532         c
            53-282              AC154108.3         80059-80288         c
            283-409             AC154108.3         77508-77634         c
            410-508             AC154108.3         77159-77257         c
            509-3381            AC154108.3         69441-72313         c
FEATURES             Location/Qualifiers
     source          1..3381
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 28.25 cM"
     gene            1..3381
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /note="zinc finger protein 175"
                     /db_xref="GeneID:210104"
                     /db_xref="MGI:MGI:2652821"
     exon            1..52
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /inference="alignment:Splign:2.1.0"
     exon            53..282
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..2886
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /note="zinc finger protein 658"
                     /codon_start=1
                     /product="zinc finger protein 175"
                     /protein_id="NP_001008549.1"
                     /db_xref="CCDS:CCDS39931.1"
                     /db_xref="GeneID:210104"
                     /db_xref="MGI:MGI:2652821"
                     /translation="MKLSQKAQRLHPQEQEGSRERLVSFEDVTVDFSQEEWRRLDSVQ
                     RHLYQDVMLEIYSHLLAVGYPVPSPGAIFRIKKRKEARTGEAKLPHPCWCQEVESEFY
                     RPQQKASEEAAFQTSKASAVTRHGLWCSILEELWQDPDPAQRDGQNQIPPWSPGASLN
                     KKTARADRDCGWKEPGKTTPFVANLFSTQKGAPRLLAKRLNPNLEANGEEQGSVTKQL
                     NGLVTSAHLLPQDSSNANCTILRETWNPCKGNQCRKVPTHKQLTEKEAHSREKLDEGT
                     ECRKVFYDESAFCKHQAAHAGEGPFVCHKCGEAFLQKTEFASHQETHPEKPYECPDCG
                     KSFSRTSNLQVHHRIHTGEKPYECRDCGKSFNNTSQLKVHYRIHTGERPYVCPVCGKA
                     FKQKSILSTHETIHTGEKPYKCTVCGKLFSCTSRLKVHYQIHMKEKPYECGDCGKAFK
                     RKSSLTVHQKIHIRQTHHECSECGKTFNQKSELSTHQRLHLGKNSHRCSDCGKSFTYA
                     SQLKMHRRVHTGEKPYKCRDCGKSFTYSFTLNVHRRIHKVEKPHKCSICGKALASKYQ
                     LEEHERIHTGEKPYVCTECGKGFHGRSGFLRHQITHTRDKPFVCHKCGKAFFQRSQLT
                     SHQQTHTGEKPYTCHYCGKSFSHTSQLTVHHRIHTGERPYKCDYCAKSFSNSSQLKEH
                     LRIHTGETPYACSECGKAFSRRSSLNLHTKIHTGEKHHICSECGKAFSQKSVLRTHQR
                     IHTGEKPYKCSDCGKALASKGQLRDHQRIHTGEKPYMCPECGKGFFGRSSLHRHQITH
                     TKERPFVCQKCGKTFIQKSALTSHQQIHTGEKPYVCPECGKGFYNKSSLPRHQMTHTR
                     GRSFVCQKCGKAFLQKSVLKCHQRTHTCKKP"
     exon            283..409
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /inference="alignment:Splign:2.1.0"
     exon            410..508
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /inference="alignment:Splign:2.1.0"
     exon            509..3381
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3359..3364
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /note="hexamer: AATAAA"
     polyA_site      3381
                     /gene="Zfp175"
                     /gene_synonym="Zfp658"
                     /note="major polyA site"
ORIGIN      
        1 cagggaggga cactgcgcgt cctgtgcaga gttctctgca ttgttgtgag aggtcaaagg
       61 caggccacat cagccaggct gggggatttt tctacctcac cacagctggc ctctctgctc
      121 agctgctctc ctgggaacct ctagccactc aaccagcttc cagttcctga gaaaaattgc
      181 atctgccagc aaagaggcaa gagaggaaac atacctgctg acatgaaatt gtcccagaag
      241 gcccagagac tgcacccaca ggagcaggaa gggtcccgtg agagattggt gtcctttgag
      301 gatgtgactg tggacttcag ccaggaggag tggcgacgcc tggactccgt ccagagacac
      361 ctgtaccagg acgtgatgct ggagatctac agccacctct tggcagtggg ctaccctgtt
      421 cctagccctg gggccatctt caggataaag aaaagaaagg aggcacggac aggagaggcc
      481 aagctcccac atccttgttg gtgtcaagaa gtggaatcag agttttacag gcctcagcag
      541 aaagcatctg aggaggcagc attccaaact agtaaggcaa gcgcagtcac aaggcatggc
      601 ttgtggtgct cgattttaga agaactgtgg caagatcctg accctgcaca aagagatggg
      661 caaaaccaga tcccaccctg gagtcctggg gcttccctca acaagaaaac agcgcgagca
      721 gatagagact gtgggtggaa agagcccggg aagaccactc ccttcgtagc taaccttttt
      781 tctacacaaa agggagctcc aaggttactt gcaaaacgtt tgaaccctaa ccttgaagcc
      841 aacggtgaag agcaaggcag tgtcacaaaa cagctgaatg gtcttgttac atctgctcac
      901 ctcctcccgc aagactcttc taatgctaac tgtacaattc ttcgtgaaac atggaatccg
      961 tgcaaaggta accagtgcag aaaagttccc acccataaac aactgacaga gaaagaagct
     1021 cattctcgtg agaaactaga tgaaggcacg gaatgtagaa aagtcttcta tgacgaatct
     1081 gctttctgta aacaccaggc agctcacgct ggagaaggac cttttgtctg tcacaagtgt
     1141 ggggaagcct tcctccagaa gacagagttt gcctcccatc aagaaactca cccagagaaa
     1201 ccttatgagt gtcccgactg cgggaagtca tttagtcgaa cgtccaacct gcaggtccac
     1261 catcgaattc acactggaga gaaaccttat gagtgtcggg actgtggcaa atcattcaat
     1321 aatacatccc agctgaaggt acattatcgg atacatacag gggagagacc ttacgtgtgt
     1381 cccgtatgtg ggaaggcctt caagcagaaa tcaatcctca gcacgcatga gacaattcac
     1441 actggggaga agccttacaa atgtaccgtt tgtgggaaac tgttcagctg tacgtcccga
     1501 ctgaaagtgc actaccagat tcatatgaag gagaaacctt atgaatgcgg tgactgtgga
     1561 aaagccttca agcgaaagtc aagcctcacc gttcaccaga agatccatat cagacaaaca
     1621 caccacgagt gcagcgagtg tgggaaaacg ttcaaccaga agtccgagct cagcactcac
     1681 cagagacttc acctgggcaa gaattcccac agatgcagcg actgtgggaa atcgttcact
     1741 tacgcatccc aactgaagat gcaccgtcgg gttcacacgg gggagaagcc ctacaagtgc
     1801 cgggactgtg ggaagtcctt tacgtactca ttcacgctga atgtgcatcg ccgaattcac
     1861 aaggtggaga agcctcacaa gtgcagcatc tgtgggaaag ctttggcgtc taagtaccaa
     1921 ctggaagagc atgagcgaat tcacacagga gagaagcctt acgtgtgtac tgaatgtgga
     1981 aaaggcttcc atggtaggtc aggtttccta agacatcaga ttactcacac gagggataaa
     2041 cctttcgtct gtcataaatg tgggaaggcc ttctttcaga ggtcacagct gacatctcat
     2101 cagcagactc acacaggaga gaagccttat acgtgccatt actgcgggaa atcattcagt
     2161 cacacatccc agctgacggt ccatcatcga attcacacag gggagagacc ttacaaatgc
     2221 gactattgtg cgaagtcgtt cagcaactcc tcccaactga aagagcatct ccgcattcat
     2281 accggggaga cgccttatgc atgttccgaa tgtgggaagg ccttcagccg acgatcgtcc
     2341 ctcaatctac acacgaaaat tcatactgga gaaaaacacc atatatgtag tgagtgtggg
     2401 aaagccttta gtcagaagtc agtactgcgg acacatcaga gaatacacac tggggaaaag
     2461 ccttacaaat gcagtgactg tgggaaggcc ctggcttcaa agggccaact tcgagatcat
     2521 cagcggattc acactggcga gaaaccctac atgtgccctg aatgtgggaa gggtttcttt
     2581 ggcaggtcgt ctttgcatag acatcagata actcacacta aggagagacc ttttgtctgt
     2641 caaaaatgcg ggaagacctt catccagaag tcagcactga cgtcccatca gcaaattcac
     2701 acaggcgaga agccctatgt gtgccctgag tgtgggaagg gcttctacaa taagtcatct
     2761 ttacctaggc atcagatgac tcacactagg gggagatctt ttgtctgtca aaaatgtggg
     2821 aaggcattcc tccagaagtc tgtgttgaaa tgccatcagc ggactcacac ttgcaagaag
     2881 ccttagcaat gccataggaa attgttccat aataaaaccc actgaggggc cctcatcatc
     2941 cctacataga aatgcagaga gcatcccaac tggatgtgca gcactgggtc tagaatggag
     3001 agagacacta ctgtgttctg agtgttaaaa ggcttttaac agcatgtcag atgataataa
     3061 atagcaagca gctcatagta gacacagttc tttttaggct cagtttttgt gtgaagcata
     3121 tttcctcata gtctataaac atattcctaa ctgaggtata atctttaaat tacttgaaga
     3181 gaatgtttta aaagaattta ttggggctgg agagatggct taagagcgct ggctgctctc
     3241 ccagaggtcc tgagttcaat tcccaacaac tacatggtgg ctcacaaccg tctataatga
     3301 gatccgatgc cctcttctgg tgtgtctgaa agcagcgaca gtgtactcac atacatgaaa
     3361 taaatctttt tttttaaagg a
//
