LOCUS       NM_009564               2770 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus zinc finger protein 64 (Zfp64), transcript variant 1,
            mRNA.
ACCESSION   NM_009564
VERSION     NM_009564.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2770)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   2  (bases 1 to 2770)
  AUTHORS   Zheng,S., Damoiseaux,R., Chen,L. and Black,D.L.
  TITLE     A broadly applicable high-throughput screening strategy identifies
            new regulators of Dlg4 (Psd-95) alternative splicing
  JOURNAL   Genome Res 23 (6), 998-1007 (2013)
   PUBMED   23636947
REFERENCE   3  (bases 1 to 2770)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2770)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 2770)
  AUTHORS   Sakamoto,K., Tamamura,Y., Katsube,K. and Yamaguchi,A.
  TITLE     Zfp64 participates in Notch signaling and regulates differentiation
            in mesenchymal cells
  JOURNAL   J Cell Sci 121 (Pt 10), 1613-1623 (2008)
   PUBMED   18430783
  REMARK    GeneRIF: data demonstrate two functions of Zfp64: (1) it is a
            downstream target of Runx2 and, (2) its cognate protein acts as a
            coactivator of Notch1, which suggests that Zfp64 mediates
            mesenchymal cell differentiation by modulating Notch signaling
REFERENCE   6  (bases 1 to 2770)
  AUTHORS   Ewart-Toland,A., Briassouli,P., de Koning,J.P., Mao,J.H., Yuan,J.,
            Chan,F., MacCarthy-Morrogh,L., Ponder,B.A., Nagase,H., Burn,J.,
            Ball,S., Almeida,M., Linardopoulos,S. and Balmain,A.
  TITLE     Identification of Stk6/STK15 as a candidate low-penetrance
            tumor-susceptibility gene in mouse and human
  JOURNAL   Nat Genet 34 (4), 403-412 (2003)
   PUBMED   12881723
REFERENCE   7  (bases 1 to 2770)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 2770)
  AUTHORS   Gaikwad,J.S., Cavender,A. and D'Souza,R.N.
  TITLE     Identification of tooth-specific downstream targets of Runx2
  JOURNAL   Gene 279 (1), 91-97 (2001)
   PUBMED   11722849
REFERENCE   9  (bases 1 to 2770)
  AUTHORS   Mishra,L., Yu,P., Cai,T., Monga,S.P. and Mishra,B.
  TITLE     Genomic structure, chromosomal mapping, and muscle-specific
            expression of a PH domain-associated intronless gene, cded/lior
  JOURNAL   Mamm Genome 10 (1), 62-67 (1999)
   PUBMED   9892736
REFERENCE   10 (bases 1 to 2770)
  AUTHORS   Mack,H.G., Beck,F. and Bowtell,D.D.
  TITLE     A search for a mammalian homologue of the Drosophila photoreceptor
            development gene glass yields Zfp64, a zinc finger encoding gene
            which maps to the distal end of mouse chromosome 2
  JOURNAL   Gene 185 (1), 11-17 (1997)
   PUBMED   9034307
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY752610.1, AK146036.1 and CX734245.1.
            
            On May 23, 2007 this sequence version replaced NM_009564.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK146036.1, SRR1660811.11915.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-332               BY752610.1         2-333
            333-1103            AK146036.1         19-789
            1104-2416           AK146036.1         792-2104
            2417-2424           CX734245.1         360-367             c
            2425-2746           AK146036.1         2113-2434
            2747-2770           CX734245.1         14-37               c
FEATURES             Location/Qualifiers
     source          1..2770
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 88.99 cM"
     gene            1..2770
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /note="zinc finger protein 64"
                     /db_xref="GeneID:22722"
                     /db_xref="MGI:MGI:107342"
     exon            1..469
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     CDS             424..2454
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /note="isoform 1 is encoded by transcript variant 1;
                     zfp-64"
                     /codon_start=1
                     /product="zinc finger protein 64 isoform 1"
                     /protein_id="NP_033590.2"
                     /db_xref="CCDS:CCDS50804.1"
                     /db_xref="GeneID:22722"
                     /db_xref="MGI:MGI:107342"
                     /translation="MNASVEGDTFSGSMQIPGGTTVLVELAPDIHICGLCKQHFSNLD
                     AFVAHKQSGCQLTTTPVTAPSTVQFVAEETEPATQTTTTTISSETQTITVSAPEFVFE
                     HGYQTYLPTESTDNQTATVISLPTKSRTKKPTAPPAQKRLGCCYPGCQFKTAYGMKDM
                     ERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSSSLNK
                     HLRIHSDERPFKCQICPYASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHM
                     RVHSGEKPFKCEFCNVRCTMKGNLKSHIRIKHSGNNFKCPHCDFLGDSKSTLRKHSRL
                     HQSEHPEKCPECSYSCSSKAALRVHERIHCTERPFKCSYCSFDTKQPSNLSKHMKKFH
                     ADMLKNEAPEKKESGRQSSRQVARLDAKKTFHCDICDASFMREDSLRSHKRQHSEYHS
                     KNSDVTVVQLHLEPSKQPAAPLTVEQIQVPLQSSQVPQFSEGRVKIIVGHQVPQTNAI
                     VQAAAAAVNIVPPTLVAQTPEEIPGNGRLQILRQVSLIAPPQSSGCPGEAGALSQPTV
                     LLTTHDQTAGAALQQALIPTTPVGTQEGTGNQTFIASSGITCSDLEGLNALIQEGTTE
                     VTVVSDGDQSIAVATTAPSIFSTQQELPKQTYSIIHGAAHPALLCPADSIPD"
     exon            470..703
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     exon            704..865
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     exon            866..928
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1180
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..2753
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2720..2725
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /note="hexamer: AATAAA"
     polyA_site      2753
                     /gene="Zfp64"
                     /gene_synonym="Gm38422"
                     /note="major polyA site"
ORIGIN      
        1 gttacgctgc cggatctgcc ctaggggagc accccgggat ttggggctcc actctcccag
       61 gccggcagcg catcctcctg gcatctgcga aggaatgagc gtctccagga gggcaagatg
      121 caaaggcgca aggcgaccac agagtccctg gcatgcctgg gatagggtgg agggatcggt
      181 gtactcgggt cttagactcc acgacctttc ccggttcctc gggagagcac cgcctgggag
      241 tcgggctggg tgcaaggggc cagcgccctc taggcagcgg aagtggcgct ggttgtacat
      301 ccgtccccgc ctcacagagt tgggagaaga ctggctggtg cgggaaatat gcaggagaaa
      361 agtctttgca taatgtagag cgagccgtgg ggctccggga gcggcgcccc aaggtctggg
      421 gccatgaacg cgagcgtgga aggagacacc ttttctggat cgatgcaaat cccaggaggc
      481 accacggtgc tggtggagct ggcaccggac atccacatct gcggcctctg taagcagcac
      541 ttcagcaatc tggatgcctt tgtggcccac aaacagagcg gctgccagct gactaccacg
      601 ccggtgacag cccccagcac ggtccagttt gtggcagagg agacagagcc tgccacccag
      661 accaccacaa cgaccatcag ttcagagact cagactatca cagtttcagc tccagagttc
      721 gtctttgaac atggctacca aacttacctg cccacggaga gcactgacaa ccagacagcc
      781 accgtgatct ctctccccac caagtcacgc accaaaaagc ccacagcacc ccctgctcag
      841 aagagactcg gctgctgcta tccaggttgc cagttcaaga ccgcctatgg catgaaggac
      901 atggagcgac acctgaagat ccacaccggt gacaaacccc acaagtgtga ggtgtgcggg
      961 aagtgcttca gccggaagga caagctgaag acgcacatgc gctgccacac gggcgtcaag
     1021 ccctacaagt gcaagacgtg cgactacgcg gcggcggaca gcagcagcct taacaagcac
     1081 ctgcgcatcc actcggacga gcgacccttc aagtgccaga tctgtcccta cgccagtcgc
     1141 aactccagcc agctcaccgt gcacctgcgc tcgcacacgg gggacgcccc cttccagtgc
     1201 tggctctgta gtgccaagtt caaaatcagc tcggacttga aaaggcacat gcgtgtgcac
     1261 tcgggggaga agcctttcaa gtgcgaattc tgcaatgtcc gctgtaccat gaaggggaac
     1321 ctcaaatcgc acatccgcat caagcacagt gggaataact tcaagtgtcc gcactgcgac
     1381 ttcctgggtg acagcaaatc caccctgcgg aagcacagtc gcctgcacca gtcggagcac
     1441 ccggagaagt gtcccgagtg cagctactcc tgttccagca aggctgcgct gcgcgtgcac
     1501 gagcgcatcc actgcaccga gcgcccgttc aagtgcagct actgcagctt cgataccaag
     1561 caacccagca acctgagcaa gcacatgaag aagttccacg ccgacatgct caagaacgag
     1621 gctccggaga agaaggagag cggcaggcag agcagccggc aggtggccag gctggatgcc
     1681 aagaagacgt tccactgcga catctgtgac gcctcgttta tgcgggagga ctcgctccgc
     1741 agccacaaac ggcagcacag tgagtaccac agtaagaact cggacgtgac tgtagtacag
     1801 cttcaccttg aacccagcaa gcagccggct gcgcccctca ccgtagagca aatccaggtc
     1861 cccctccagt ccagccaggt gccccagttc agcgagggga gggtcaagat catcgtgggg
     1921 catcaggtgc ctcagacgaa cgccatagtc caagcggccg cagctgccgt caacattgtg
     1981 ccccccaccc tggtagccca gaccccagag gagatcccag ggaacggccg gctacagatc
     2041 cttcgccagg tcagtctcat tgcccctcct cagtcctccg ggtgtcccgg cgaagcaggt
     2101 gccctgagtc agccaactgt cctgctgacc acccatgatc agacggcagg ggccgccctg
     2161 cagcaggctc tgatccccac caccccggtt gggacccagg aaggcacggg aaaccagaca
     2221 ttcattgcca gttcgggcat cacgtgctcg gacttggaag gccttaacgc tctgattcag
     2281 gagggaacga cggaagtgac tgtggtgagc gatggggacc agagcatcgc agtggccacc
     2341 acggcaccct ctatcttctc tacccagcag gaactgccca agcagactta ctccatcatc
     2401 cacggggcgg cacaccccgc cctgctctgt cccgctgact ccattcctga ttagtctgga
     2461 gggaggggtg acagacaaga caaactgcga gaggagtact gtgagaggct cctggtcccg
     2521 tataaataat tgtattttat acagtttatg taatttttta acagggtatc aacgtggaga
     2581 ccattctccc tcaagctctt gttgattgtg tcttaatggt taccaaggct gattccaatg
     2641 tggagttgga attcaccaca gtaggactga atacattcgt ttgtttttcc atgtttcgga
     2701 tttaattttt ttcaactgga ataaaggtgt ttgggtttgg gtttttcatc gtaaaaaaaa
     2761 aaaaaaaaaa
//
