LOCUS       NM_001411605            1475 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus zinc finger protein 637 (Zfp637), transcript variant
            9, mRNA.
ACCESSION   NM_001411605
VERSION     NM_001411605.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1475)
  AUTHORS   Marenne,G., Hendricks,A.E., Perdikari,A., Bounds,R., Payne,F.,
            Keogh,J.M., Lelliott,C.J., Henning,E., Pathan,S., Ashford,S.,
            Bochukova,E.G., Mistry,V., Daly,A., Hayward,C., Wareham,N.J.,
            O'Rahilly,S., Langenberg,C., Wheeler,E., Zeggini,E., Farooqi,I.S.
            and Barroso,I.
  CONSRTM   INTERVAL, UK10K Consortium
  TITLE     Exome Sequencing Identifies Genes and Gene Sets Contributing to
            Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC
            Transcription
  JOURNAL   Cell Metab 31 (6), 1107-1119 (2020)
   PUBMED   32492392
REFERENCE   3  (bases 1 to 1475)
  AUTHORS   Gao,B., Li,K., Wei,Y.Y., Zhang,J., Li,J., Zhang,L., Gao,J.P.,
            Li,Y.Y., Huang,L.G., Lin,P. and Wei,Y.Q.
  TITLE     Zinc finger protein 637 protects cells against oxidative
            stress-induced premature senescence by mTERT-mediated telomerase
            activity and telomere maintenance
  JOURNAL   Cell Death Dis 5 (7), e1334 (2014)
   PUBMED   25032857
  REMARK    GeneRIF: The overexpression of Zfp637 markedly increases mTERT
            expression and telomerase activity, maintains telomere length, and
            inhibits H2O2 and D-galactose-induced senescence.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1475)
  AUTHORS   Li,K., Wei,Y., Zhang,J., Li,J., Gao,B., Huang,L., Lin,P. and Wei,Y.
  TITLE     Cytoplasmic expression, antibody production, and characterization
            of the novel zinc finger protein 637
  JOURNAL   Appl Microbiol Biotechnol 97 (2), 741-749 (2013)
   PUBMED   22733115
REFERENCE   5  (bases 1 to 1475)
  AUTHORS   Li,K., Zhang,J., Ren,J.J., Wang,Q., Yang,K.Y., Xiong,Z.J.,
            Mao,Y.Q., Qi,Y.Y., Chen,X.W., Lan,F., Wang,X.J., Xiao,H.Y., Lin,P.
            and Wei,Y.Q.
  TITLE     A novel zinc finger protein Zfp637 behaves as a repressive
            regulator in myogenic cellular differentiation
  JOURNAL   J Cell Biochem 110 (2), 352-362 (2010)
   PUBMED   20235149
  REMARK    GeneRIF: results suggest that Zfp637 inhibits muscle
            differentiation through a defect in the cell cycle exit by
            potentially regulating mTERT expression in C2C12 myoblasts
REFERENCE   6  (bases 1 to 1475)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 1475)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153583.10 and AC153918.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784646.971271.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-194               AC153583.10        194141-194334
            195-361             AC153583.10        195567-195733
            362-501             AC153583.10        196190-196329
            502-1475            AC153918.4         134174-135147       c
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 55.59 cM"
     gene            1..1475
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /note="zinc finger protein 637"
                     /db_xref="GeneID:232337"
                     /db_xref="MGI:MGI:2448537"
     exon            1..194
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /inference="alignment:Splign:2.1.0"
     exon            195..361
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /inference="alignment:Splign:2.1.0"
     exon            362..501
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /inference="alignment:Splign:2.1.0"
     CDS             432..1292
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /note="isoform 1 is encoded by transcript variant 9; zinc
                     finger protein 32"
                     /codon_start=1
                     /product="zinc finger protein 32 isoform 1"
                     /protein_id="NP_001398534.1"
                     /db_xref="GeneID:232337"
                     /db_xref="MGI:MGI:2448537"
                     /translation="MFGFPTATLLDCHGRYAQNVAFFTYWCILHDFPLVLPDVMTEAH
                     KYDPSEATGSSSWDFQSSFRREKLEQKSPESKALQEDSPGVRQKVYDCQECGKSFRQK
                     GSLTLHERIHTGQKPFECTQCGKSFRAKGNLVTHQRIHTGEKPYQCKECGKSFSQRGS
                     LAVHERLHTGQKPYECAICQRSFRNQSNLAVHRRVHSGEKPYRCDQCGKAFSQKGSLI
                     VHIRVHTGLKPYACSHCRKSFHTRGNCLLHGKVHTGETPYLCGQCGKSFTQRGSLAVH
                     QRSCSQRLTL"
     exon            502..1475
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1453..1458
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /note="hexamer: AATAAA"
     polyA_site      1475
                     /gene="Zfp637"
                     /gene_synonym="Znf32"
                     /note="major polyA site"
ORIGIN      
        1 agcgttgcag cggctgctac gggctcggcg ccggctttgt ctgtctgcgg gcgcgcgccg
       61 ctgcggtgag tgttgctgag gccggggctg tgcgcccgag agagggggct gtgtcttgag
      121 cctgctgctc cggccagggc gcgtgagcag gccaggctgg ccgtccgggc caaaatcgcc
      181 aaccgcagac aagggtcctt gtaacttgag gggagctgaa aaggaaagct ggagctattt
      241 cttcctaaca ccagtcagga aggctggtgt gctgacttct tgcctggaaa gtagagaacc
      301 ccaatttttt atcaagacca aatgcaagca gagcggccct tacctgggga ctaacagtac
      361 agttctccag accagcccat ggaagaatca tatgaagagg cggtgatcaa agtcagcgag
      421 caggagtgga catgtttggg ttcccaacag ctaccctgct ggactgtcat ggaagatacg
      481 cccagaatgt agcctttttc acatattggt gcatcttaca tgacttccct ctcgttttac
      541 cagatgtgat gacagaagcc cacaagtatg atccttcaga ggccacagga tcctcaagct
      601 gggatttcca gagctctttc agaagagaga agctggaaca aaagtccccg gagtctaagg
      661 ccctccagga agactcacct ggagtgaggc agaaggtcta tgattgccag gaatgtggga
      721 agtctttccg gcagaaaggg agcctaacgc tgcacgagag aatccacact ggtcagaagc
      781 cctttgagtg cacccagtgt gggaaaagct tcagggccaa gggcaacctg gttacacatc
      841 agcggatcca cacaggagag aagccctatc agtgcaaaga gtgtgggaaa agcttcagtc
      901 agcgaggcag cctggctgtc cacgagagac tccacactgg acagaaaccc tacgagtgtg
      961 ccatttgcca gaggagcttc cgaaatcaaa gtaacctcgc cgtgcaccga agagttcaca
     1021 gcggtgagaa gccctataga tgcgaccagt gtggaaaagc tttcagccag aaaggaagct
     1081 taattgtgca catccgcgtc cacacgggtc tgaagcccta cgcgtgttcc cactgcagga
     1141 agagcttcca taccaggggc aactgtctcc tgcatggaaa agtccacacg ggagagacac
     1201 cctatctctg tggccagtgt gggaaaagtt tcactcagag agggagcctg gctgtgcacc
     1261 agcgaagctg ctcacaacgg ctcactctgt aaacacccct caaaggaagt tcttcttacc
     1321 cattgagagt acaaagccct cagtaatcaa gagttttacc cagtgtcata gggtaagtgg
     1381 aagttctttc agaaggacca gcctttggta gggcaaactg actttttccc tctcccccaa
     1441 atgaatatga gaaataaatg tcctgtttat catta
//
