LOCUS       NM_001177570            4818 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 616 (Zfp616), mRNA.
ACCESSION   NM_001177570 XM_001480634 XM_282967
VERSION     NM_001177570.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4818)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4818)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4818)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL611937.6.
            
            On or before Apr 17, 2010 this sequence version replaced
            XM_001480634.1, XM_282967.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC083001.1, CA561006.1 [ECO:0000331]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AL611937.6         18662-18671
            11-178              AL611937.6         27935-28102
            179-305             AL611937.6         28835-28961
            306-388             AL611937.6         29423-29505
            389-4818            AL611937.6         40637-45066
FEATURES             Location/Qualifiers
     source          1..4818
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.74 cM"
     gene            1..4818
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /note="zinc finger protein 616"
                     /db_xref="GeneID:327963"
                     /db_xref="MGI:MGI:3650906"
     exon            1..10
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /inference="alignment:Splign:2.1.0"
     exon            11..178
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /inference="alignment:Splign:2.1.0"
     exon            179..305
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /inference="alignment:Splign:2.1.0"
     exon            306..388
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /inference="alignment:Splign:2.1.0"
     exon            389..4818
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /inference="alignment:Splign:2.1.0"
     CDS             424..3387
                     /gene="Zfp616"
                     /gene_synonym="Gm12330"
                     /note="KRAB box containing protein; novel KRAB box
                     containing protein"
                     /codon_start=1
                     /product="zinc finger protein 616"
                     /protein_id="NP_001171041.1"
                     /db_xref="CCDS:CCDS56793.1"
                     /db_xref="GeneID:327963"
                     /db_xref="MGI:MGI:3650906"
                     /translation="MVCTQNYFQKEITQVFGLNGLLDLYRKKFWEYRSGGEEHEICDY
                     ENYLLAKHICFNSEKNKGVLAIPERTQAESLPFLQLETTLAEFLQILKCNNVLHRNTK
                     TLKSDIWVNKPTSLKHLSSSMGFNSTSILYEQRRYWRREKITEYHQCERYFSKNSLQL
                     PQQLNLLCDKFYHVGQHKKMSMYAVKLGTYHVEGSCGNSNRVNDSNMGYIKNPFLKYC
                     QNNQHGEILYQGDVILYDSHHETILSKNEISKCISENHYNHDSRQAMSNHCSQSSLQQ
                     QDHTTWSLYKNDWQDDILNDSLILQVYNRMWTKGDFNKYTCDTYRNALIESLYLEKDN
                     MKHIKRQLSQAPGYNKVLNFNSNVIQHDSNHNGKGIQKVKVHLYGIFNIQNLLRHSNL
                     SVEEKPSKYKTPEKCSNKSSGLMVFQARGKPWKCVQCGKSFAQYSALQNPHRICTVKK
                     LYSCKECLKSFTWFSKLQAHHRIHTTQELYKSNKCGESFTQSSNLQVYQRIHHTGDKP
                     YKCNECGKYFTHSSSLKDHQRIHARHKPYKCNNCGKSFIKSSDLKGHYRIHTGDKPYK
                     CNNCRKSFTQSSGLKRHYRIHTGDKPYKCNECGKYFTQSSNLQVHQRIHTKDKPYKCN
                     ECGKYFAHSSSLKVHHRIHTRNKTYKCNNCGKSFIRSSDLKRHYRIHTGNKPYKCNDC
                     GKYFTHSSSLKGHHRIHTRDKPYKCNNCGKSFRQSSSLKRHYRIHTGDKPYKCNECGK
                     YFACSSSLKRHHRIHTGDKPYKCNECGKYFAQSSNLQVHQRIHTKDKPYKCNECGKYF
                     ARSSSLKNHHRIHTGDKPYKCNECGKYFAQSSNLQVHQRIHTKDKPYKCNECGKYFAQ
                     YSNLQVHQRIHTKDKPYKCNECGKYFARSSSLKDHHRIHTGDKPYKCNECGKYFAQSS
                     NLQVHQRIHTKDKPYKCNECGKYFAQYSNLQVHQRIHTGDKPYKCNECGKYFASSSNL
                     KVHHRIHTGYKPLQM"
ORIGIN      
        1 aagagataat aaagcttgtt agagatttga ttcctgcttc ccactcctca gttttaccag
       61 ggacagggag gacctgctgc ctctgaataa agagtggctt ctgggaagtg aaattttagt
      121 ataaactttt gtgaaacatt ttattctgaa ggtgaagaaa aaaatgtgtt cttcacaggg
      181 tgcattgacg ttcatggatg tggctataga gttctctaag gaggagtggg aatgtctgaa
      241 ttctgcccaa agggctttgt acagagacgt catgttggag aattacaaca acctggtttc
      301 tgtgggtgtt gctgtttcaa aacgagaggt aatcatctgt cttgaacaaa acaaagaacc
      361 atggattgtt gatgcagagg aaacacaact ttgtcttgtg aacatactga gaatctacta
      421 caaatggtgt gtacacaaaa ttattttcaa aaagaaataa cacaagtatt tggacttaat
      481 ggtcttttag acctatatag aaagaagttt tgggaatata gaagtggtgg tgaggagcat
      541 gaaatatgtg attatgaaaa ttatctgctg gcaaaacaca tctgttttaa ttctgaaaag
      601 aataaaggag ttctagctat tcctgagaga actcaggctg agtcactccc atttttacaa
      661 ttggagacta ctctagcaga atttttacaa attttgaaat gcaacaatgt tctacacagg
      721 aatacaaaaa ccttaaagag tgacatttgg gtgaataaac ccacttccct gaagcattta
      781 tcaagtagta tgggatttaa cagtacttca atactttatg aacaaaggag atattggaga
      841 agagaaaaaa ttactgaata tcatcaatgt gaaagatatt tctctaaaaa ttcattacag
      901 cttcctcaac aattaaatct actctgtgac aagttctacc atgtaggtca acataagaaa
      961 atgtccatgt atgcagtgaa acttggaaca tatcatgtgg aaggtagttg tggaaactcc
     1021 aacagagtaa atgatagtaa catgggctat attaaaaacc cttttctgaa gtattgccaa
     1081 aacaatcaac atggagagat tttataccaa ggtgatgtca tattatatga ttctcatcat
     1141 gaaacaattc taagtaaaaa tgagataagt aaatgtattt cagaaaatca ttataaccat
     1201 gatagtagac aggctatgtc taatcactgc tctcagtcat ctttgcaaca gcaggatcat
     1261 accacatgga gcctttataa aaatgactgg caggatgaca ttttaaatga ttccttaatt
     1321 cttcaggttt ataacagaat gtggactaaa ggagatttca acaaatatac atgtgataca
     1381 tacaggaatg ctttaattga atcgttatac ttagagaaag ataacatgaa acacattaaa
     1441 agacaacttt cccaggcccc agggtataat aaggtcttga atttcaattc caatgtcatt
     1501 caacacgatt caaaccataa tggaaaggga atccagaaag tcaaagtaca tttgtatggt
     1561 attttcaata tacaaaatct cttgagacat tcaaatttat cagttgagga aaaaccctca
     1621 aaatataaaa caccagagaa atgctccaat aaatcctcag gccttatggt atttcaagct
     1681 agagggaaac catggaaatg tgtgcaatgt ggcaagtcct ttgctcagta ctcagctctt
     1741 caaaaccctc acaggatctg tactgtaaag aaactgtata gttgtaagga atgtttaaaa
     1801 tcatttactt ggttctcaaa acttcaagct caccacagaa tacatactac acaggaactt
     1861 tataaatcta ataagtgtgg ggaatcattt acccagtcat caaatcttca agtttatcag
     1921 agaatccacc acacaggaga caagccttac aaatgtaatg aatgtggtaa atattttacc
     1981 cattcctcaa gtcttaaaga tcaccagaga atccatgcaa gacacaaacc ttacaaatgt
     2041 aataactgtg ggaaaagttt tataaagtcc tcagatctta aagggcacta cagaatccac
     2101 acaggagaca aaccctacaa atgtaataac tgtaggaaaa gttttacaca gtcctcaggt
     2161 cttaaaaggc actacagaat ccacacagga gacaaacctt acaaatgtaa tgaatgtggt
     2221 aaatatttta cccagtcttc aaatcttcaa gttcatcaga gaatccacac aaaagacaaa
     2281 ccttacaaat gtaatgaatg tggtaaatat tttgcccatt cctcaagtct taaagtacac
     2341 cacagaatcc atacaagaaa caaaacttat aaatgtaata actgtgggaa aagttttata
     2401 cggtcctcag atcttaaaag gcactataga atccacacag gaaacaagcc ttacaaatgt
     2461 aatgactgtg gtaaatattt tacccattcc tcaagtctta aaggtcacca cagaatccat
     2521 acaagagaca agccttacaa atgtaataac tgtgggaaaa gttttagaca gtcctcaagt
     2581 cttaaaaggc actacagaat ccacacagga gacaaacctt acaaatgtaa tgaatgtggt
     2641 aaatattttg cctgttcctc aagtcttaaa aggcaccaca gaatccacac aggagacaaa
     2701 ccttacaaat gtaatgaatg tggtaaatat tttgcccagt cttcaaatct tcaagttcat
     2761 cagagaatcc acacaaaaga caaaccttac aaatgtaatg aatgtggtaa atattttgcc
     2821 cgttcctcaa gtcttaaaaa tcaccacaga atccacacag gagacaaacc ttacaaatgt
     2881 aatgaatgtg gtaaatattt tgcccagtct tcaaatcttc aagttcatca gagaatccac
     2941 acaaaagaca aaccttacaa atgtaatgaa tgtggtaagt attttgccca gtattcaaat
     3001 cttcaagttc atcagagaat ccacacaaaa gacaaacctt acaaatgtaa tgaatgtggt
     3061 aaatattttg cccgttcctc aagtcttaaa gatcaccaca gaatccacac aggagacaaa
     3121 ccttacaaat gtaatgaatg tggtaaatat tttgcccagt cttcaaatct tcaagttcat
     3181 cagagaatcc acacaaaaga caaaccttac aaatgtaatg aatgtggtaa gtattttgcc
     3241 cagtattcaa atcttcaagt tcatcagaga atccacacag gagacaaacc ttacaaatgt
     3301 aatgaatgtg gtaaatattt tgccagttcc tcaaatctta aagtacacca cagaatccac
     3361 acaggataca aacctttaca aatgtaatga atgtggtaaa tattttacct gattttcaag
     3421 tcttaaagtt caccccagac ttcatactgt agacaaacct gttaaaggta attagtgtgg
     3481 gaaatcattt acacagtcct caaaactaca agcttcccac agaatacaca ctgaacatcg
     3541 accttataaa tctaataatt gtgggaaatc atttacccag taatcaagtc ctctagctca
     3601 ccacagagtc catacaagag acaaaccggc aaatgtaatt aatgtggaaa aagctttata
     3661 tagtcctcag atcttatcaa ttagtacata atccacatag gagacaaact ttacaaatct
     3721 aagaaatgtg gcatgtcttt tacctgatcc tcatctcttc aagttcatca aagaatccat
     3781 actggaaaac aaccatatat gtggaaacga ctgtggaaaa tctttttcct gctcctcaaa
     3841 tgttcattct cactagagta tccatacagg agacaaattg aaaaaatata gtgagtatgg
     3901 agttgatttc ccaagtcctc gactctccaa tgtcaccaca gaatccatcc tgggggcaaa
     3961 cctttcaaat atactgaatg ttaacaatcc tttaccctgt tctcagtaac tttataggtg
     4021 taatgaatgt gtaaaataca tttcccagtc ctcaaatctt caaggtgacc acagaatcca
     4081 tactgcagca aacattgtca atgtaaagaa cgtagaaagc ccttcacaca gaaatcatat
     4141 ttttaaacct gacatagcat ggatactaga gagaaactgt acaaatgtag ataatctgac
     4201 aagtcatttc tcactttctc aaacctgtgg ccacctagaa gatcagtgca atagaccaag
     4261 ttgatgagta attactgtcc tagtatgaat acagaaacct ggtatttaca atgagaaaca
     4321 tgtttgtaag tatttaaata atgttaaaac cttactctct atcagagaac tcacagagga
     4381 aagccctgac cttattagga attggaaacg ttttacccag aaacacagct gatagtcata
     4441 ttaagtagtt atttccaaaa taaaatatga aaaaaatctt tcacccagta ttaatctaat
     4501 tataattata atcacatcat aattagtaat ggtatagaat tcaggttcaa acaaatttag
     4561 agaagtagta ttttaaaatg taaggattta agccataata atattattga atatccttat
     4621 acaaaactgt tgcaaaatgt tctgtatagt ttagtaggct agaatattga catttgtgag
     4681 atatggtcta tgtgaagctt attttgtttt tactctttga gcttttataa aatatacata
     4741 ataggaaatt tttaatctca aaataatccc ttctttgtca gaattatcaa taaacatatt
     4801 acaactgtct tcctattc
//
