LOCUS       NM_175751               6112 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus zinc finger protein 608 (Zfp608), transcript variant
            1, mRNA.
ACCESSION   NM_175751 XM_001000817 XM_001000830 XM_001000847 XM_001000861
            XM_001000874 XM_001000888 XM_001000902 XM_001000914 XM_993937
            XM_993952 XM_993993 XM_994038 XM_994057 XM_994076
VERSION     NM_175751.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6112)
  AUTHORS   Reed,N.P., Henderson,M.A., Oltz,E.M. and Aune,T.M.
  TITLE     Reciprocal regulation of Rag expression in thymocytes by the
            zinc-finger proteins, Zfp608 and Zfp609
  JOURNAL   Genes Immun 14 (1), 7-12 (2013)
   PUBMED   23076336
  REMARK    GeneRIF: Zfp608 represses Rag1 and Rag2 expression indirectly by
            repressing the expression of Zfp609 in tymocytes.
REFERENCE   2  (bases 1 to 6112)
  AUTHORS   Ayoub,A.E., Oh,S., Xie,Y., Leng,J., Cotney,J., Dominguez,M.H.,
            Noonan,J.P. and Rakic,P.
  TITLE     Transcriptional programs in transient embryonic zones of the
            cerebral cortex defined by high-resolution mRNA sequencing
  JOURNAL   Proc Natl Acad Sci U S A 108 (36), 14950-14955 (2011)
   PUBMED   21873192
REFERENCE   3  (bases 1 to 6112)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127314.4 and BC092219.1.
            
            On Feb 5, 2010 this sequence version replaced NM_175751.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092219.1, SRR9219380.33706.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-353               AC127314.4         12815-13167
            354-4248            BC092219.1         87-3981
            4249-4666           AC127314.4         107358-107775
            4667-5075           BC092219.1         4400-4808
            5076-6112           AC127314.4         113914-114950
FEATURES             Location/Qualifiers
     source          1..6112
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 29.28 cM"
     gene            1..6112
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="zinc finger protein 608"
                     /db_xref="GeneID:269023"
                     /db_xref="MGI:MGI:2442338"
     exon            1..353
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            354..1449
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     CDS             547..5082
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="zinc finger protein 608 isoform 1"
                     /protein_id="NP_786927.2"
                     /db_xref="CCDS:CCDS37824.1"
                     /db_xref="GeneID:269023"
                     /db_xref="MGI:MGI:2442338"
                     /translation="MSVNVSTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKD
                     RQKFEMNNSTNTTTNTTKDCGGPASNGTCSTSALADGLKFASVQPSAPQGNSHKETSK
                     SKVKRAKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSGGG
                     SSNPNSNGTSTGTSAATAGAGSCGKSKEEKPGKSHSSRGAKRDKDAARSRKEKHDLLQ
                     GHQNGGGGQAPSGGHLYGFGTKSNGSGASPFHCGGAGSGSVGAAGEVSKTAPDSTLMG
                     NSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLAPQIPPSYFPPSSSN
                     IAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVN
                     VTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGSEVSF
                     TESRGLQSKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELD
                     LNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHI
                     NGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECNESSTSVSSYDQTKAP
                     GSPGAGNPPGTPKGKREHVSNGPGPIIGSKTGKNSGKKRGLNNELNNLPVISNMTAAL
                     DICSATDSNLTAEMPKLEAEGLIDKKSLGDKEKGKKANNCKMDKNLSKLKSARPIAPA
                     PAPTPPQLIAIPTAAFTSTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPI
                     TVNPALVSLKDRKKKEKRKLKDKEGKETGGPKMDAKLGKLEEAKAASKDLSGHFLKDH
                     LGKSEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAP
                     MAPLHVLTQNGAESAAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDTFSNKD
                     GVVKGHPSTSAQPSQLKESHSPYYHGYEPYYSPSYMHPGQVGAPAAGNGGSTQGMKIK
                     KESEEDAEKKDKAEQLESKKVDHTSAPLQPQHQSVITQRHPALAQSLYYGQYAYGLYM
                     DQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQSGRGDCERKAELPLKELGKEDNKQKN
                     MPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMEN
                     HQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPESRTWHHYVYQPKYLDQQKPEELDRE
                     KKLKEDSPRKTPNKESGVSSLPVSLTNIKEEPKEGKRPDSQSVEENKLKNDDRKTPVN
                     WKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLS
                     PGFHYPVYGKMSGREEAEKVNTSPSINTKTASEAKALDLLQHHANQYRSKSPAPVEKA
                     STEREREAERERDRHSPFSQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQ
                     VAAQASASGMFPAQRRE"
     exon            1450..1705
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            1706..1793
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..4248
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            4249..4666
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            4667..4839
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            4840..4993
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            4994..5075
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     exon            5076..6112
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5694..5699
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="hexamer: AATAAA"
     polyA_site      5737
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="major polyA site"
     regulatory      6078..6083
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="hexamer: ATTAAA"
     polyA_site      6109
                     /gene="Zfp608"
                     /gene_synonym="4932417D18Rik; D430007A19Rik; Znf608"
                     /note="major polyA site"
ORIGIN      
        1 ccctcccctc cccctctcct ctccctctct ctcaacaccc tattattctg aatgcttgtt
       61 aagaggaaaa acacccttcg gtgctcgggt tgtgaacgtg aagcatctct cagctgcaca
      121 gtgacacatt ttttttaagg agaaaaggac tccagagctt tttgccaaat gggggatggg
      181 ggagtggaat gatgttactg agtgattatt ttggctgaga tgtgttactt ggtttcttcc
      241 tttttgatca tttggtgttt aagtaaaatg aggcacaggg ctgtgtgcct agtggactga
      301 gaaatgcttt tttgatttgc cggcctaatt aaaaaatgat aaaggattta aaggagaagc
      361 tggacctcga gtgaaggaag tgagatccct ggacacattt ttgggggcag gaaaaagaag
      421 aggaaaattg caaggaaaaa aaaatttttt tttctttacg agaaaaccca gaggagctaa
      481 acgaatgtcc cctcatccct caaagaaagt tcatcgggtt tttaatctcg agagctcatc
      541 ttcaggatgt ccgtgaacgt ttcgactgca ggaaaaggtg tggatccaaa tacagttgat
      601 acttatgaca gtggcgatga ttgggaaatc ggggttggaa atttaatcat tgatttggac
      661 gccgatttgg aaaaggacag acaaaaattt gagatgaata attccaccaa caccactacc
      721 aacaccacta aggattgtgg aggtccggcc tccaatggga cctgttctac ctcagcctta
      781 gctgatggcc taaaatttgc ttctgttcag ccctccgctc cccaggggaa ttcacacaaa
      841 gaaaccagca aatcaaaagt gaaaagggct aaaacttcta aggatgctaa taaatctctg
      901 ccttctgctg ccttgtatgg aattcccgag atcagcagca ctggcaagag gcaggaagtc
      961 caagggcgcc ctggagaggc tactggcatg aattcagcgc tgggtcaaag tgtgagcggc
     1021 ggcggcagca gcaacccaaa cagcaacggt accagcaccg ggacctcggc tgccaccgcg
     1081 ggggcaggct cctgtgggaa aagcaaggaa gagaagccag ggaaaagcca cagcagccga
     1141 ggcgccaagc gggataagga tgctgcgaga tcccggaaag agaaacacga cctgctgcag
     1201 ggccaccaga atggcggcgg aggccaggcc ccctccggtg gtcacctcta tggctttggg
     1261 accaagagca atggaagtgg cgcgagcccc tttcactgtg ggggcgctgg gagtggcagc
     1321 gttggggctg caggggaagt tagcaaaact gctccggatt caacgctcat gggaaactct
     1381 atgctggtca agaaggaaga ggaggaggag gagagccaca ggcgaatcaa gaaactgaaa
     1441 actgagaagg ttgaccccct gtttacagtg ccggcaccac cgccgccgat tgccagcagt
     1501 ctcgcacctc agattccgcc ctcctacttt cccccatctt catccaatat tgcagcacca
     1561 gtcgaacagc ttttggttcg gactcggtcc gtgggtgtca atacgtgtga agttggagta
     1621 gtgacagagc cagagtgtct tgggccctgt gaacctggga ccagtgtcaa tttggaaggg
     1681 atcgtgtggc atgaaacaga agaaggtgtc ctagtggtca atgtcacatg gaggaacaaa
     1741 acctacgtgg ggaccctcct agactgcacc aagcacgact gggcccctcc ccggttttgc
     1801 gaatcaccga caagtgacct ggaaatgcga gggggccggg gcagagggaa gagagcgagg
     1861 tctgccgcgg ctgccccagg ctccgaggtc agcttcaccg agtccagagg gctgcagagc
     1921 aagaacagag ggggagccaa tgggaaaggg aggcgtggca gcctcaacgc cagcggacga
     1981 aggacacccc caaactgtgc tgcagaggac ataaaagcca gcccttcctc aaccaacaaa
     2041 aggaagaaca agcccccaat ggagttggat ctgaactcga gctctgagga cagtaagccc
     2101 gggaagcgag tgcgcacgaa ttccagaagc acgcctacca ctcctcaggg gaagccagag
     2161 actacttttt tggaccaagg ctgctcctct ccagtgttaa ttgattgtcc ccacccaaac
     2221 tgcaacaaaa aatataagca cataaacggc ctgaggtacc accaggcaca tgcgcactta
     2281 gacccggaaa acaaactaga gttcgagccg gatagcgagg acaagatctc agactgtgag
     2341 gaagccttga gcaacgtggc cctcgaatgc aacgagtcaa gcacaagtgt gtcatcatac
     2401 gatcagacga aagcacctgg gtcccccggg gctgggaacc cccctgggac acccaaggga
     2461 aagagagagc acgtgagcaa tggcccaggt cctattatag gttcgaaaac tggcaagaat
     2521 tctggcaaga agaggggcct taacaacgaa ctgaacaacc ttccggtcat ctccaacatg
     2581 acggccgctt tagacatttg ttcagccaca gacagcaatc taacggcgga aatgcccaaa
     2641 ttggaagcgg aaggactgat tgacaagaaa agtttggggg ataaagaaaa gggcaaaaaa
     2701 gcaaacaatt gcaaaatgga caaaaacctc tccaaactga aaagcgcccg ccccattgcc
     2761 cccgcccctg cccctacgcc cccacagctg attgctatac cgactgcagc cttcacatcc
     2821 accaccacag ggaccatacc tggactgccc tccctcacga ccactgtggt ccaggctaca
     2881 ccaaagagcc ctccattgaa acctattcaa ccaaagccca caattatggg ggagcccatc
     2941 accgtgaacc cagctctggt gtcactcaaa gacagaaaga aaaaggagaa gcgaaagctc
     3001 aaggacaaag aagggaaaga gactggaggt cccaaaatgg atgctaagct ggggaagctg
     3061 gaggaagcca aggcggctag caaggatttg tctgggcatt ttttaaagga ccatctcggt
     3121 aagagcgaag ggctggctaa tggattgtca gagtctcagg agagccgcat ggccagcatc
     3181 aaagccgagg ccgataaggt ttacacattc acggacaatg cccccagccc ttccatcggg
     3241 agtgcctcac gcatggaatg cagtaccttg gtgaatgggc aagcacccat ggcaccactg
     3301 catgtattga cccagaatgg ggctgagagc gcagcagcta agaccagcag tccagcctat
     3361 tcggacatat cagatgctgc agatgatggc ggttctgaca gcaggtcaga gggcatgagg
     3421 tcaaaggcca gttccccatc ggataccttt tctaacaaag acggtgttgt gaaagggcat
     3481 ccttcaactt cagcacagcc atctcagctg aaagagtccc attctcccta ttaccatggc
     3541 tatgagcctt actattctcc gagttacatg caccctggac aggttggtgc cccggcagct
     3601 gggaatggtg ggagcacaca gggcatgaag atcaagaagg agtcagagga agatgcggag
     3661 aagaaagaca aggcggaaca gttggagtcc aagaaagtag accatacttc tgcacccctg
     3721 cagcctcagc accagtcagt catcacccag agacaccctg ccctggctca gtcactttat
     3781 tacggccagt atgcctacgg gctctatatg gaccagaaat ctctgatggc taccagccct
     3841 gcctacagac agcagtatga gaagtactat gaggaccaga gactggcaga gcagaaaatg
     3901 gcccagagtg ggagaggaga ctgtgaaaga aaggctgaac tccccttgaa agaactgggc
     3961 aaggaagaca ataagcagaa aaacatgcca tcagccacta tctcaaaagc tccctctacc
     4021 ccggagccta acaaaaacca ttctaaacta gggccatcag tgcctaataa aactgaggag
     4081 acaggtaaat cacagcttct ctccagtcac cagcagcagc ttcaggccga cagcttcaaa
     4141 gctaagcaga tggaaaacca ccagcttatt aaggaggctg tagaaatgaa gtctgtcatg
     4201 gactctatga agcagacagg tgtagaccca acctcgagat ttaaacaaga tccagagtca
     4261 aggacatggc accattatgt ataccagccc aagtacctgg accaacaaaa gccagaagaa
     4321 cttgacagag aaaagaaatt gaaagaggac agtccaagga agactcctaa caaagagagt
     4381 ggcgtgtcca gtctccccgt gtcattaaca aacatcaaag aggagcccaa agagggcaag
     4441 cgtcctgatt cccagtcggt ggaggagaac aagctaaaga atgatgatcg gaagacaccg
     4501 gtgaactgga aggactctcg ggggacacga gtggccgtgt cctcacccat gagtcagcac
     4561 cagtcctaca tacaatactt gcatgcttat ccttacccac agatgtatga ccccagccac
     4621 cctgcatacc gggctgtctc tcctgtctta atgcacagtt accctggggc ctatctctct
     4681 ccaggatttc attatcctgt ttatggaaag atgtctggga gagaagaggc agagaaagtc
     4741 aatactagtc ccagcatcaa cacaaaaaca gccagcgaag ccaaagccct ggacctactc
     4801 caacatcacg ccaaccaata ccgcagcaag tcccctgctc ctgtggagaa ggcttccacg
     4861 gagcgagaac gggaagcaga gcgggaacgg gatcgccact cccccttcag ccagcggcac
     4921 ctgcacacac accaccacac ccatgttggc atgggctacc ctctcatccc tggtcaatac
     4981 gacccttttc aaggcttgac ctctgctgcc ctagttgcct ctcagcaggt ggctgcccag
     5041 gcatctgctt ctggaatgtt tcctgcacag agaagagaat aacagaatcg gaagtgtccg
     5101 gtgccatgtg actggatcac atggggaagc gctttatata gacatcagtt ccatggtgtt
     5161 aatttgaaat gccttaatgg caggcaaaaa accagtcatt tcattttgta aattacagat
     5221 tttatcacag agtaacaaat gttgctgtaa ttaaacttct gttttatata tatgtatata
     5281 tatacgtata catatctgta tatatacata tatatatata catatatata tatatattct
     5341 ttactttttt gtaacagtaa ccaggctcgc acacacaggg tctgctgcca agttgcaaac
     5401 cactcagtaa aggaaattaa aaaagaaaaa aaaatgtatt tgtcatgttg aaagtgttag
     5461 ccacaacagg ctgcttacat tcttttcctt ttaaattgta aataaataat gttctgtatc
     5521 agtgtgcctg aaccttgcat atccttcatc tctctcccat aaaacccctc agaaaggcca
     5581 actgtgatga tgacacttgg tacaatttag atgtctaatt ggtggctcct cttaaagatg
     5641 catcagtgta aaaaatgtcc ccgtggtcac tctttgtact tgtttattgt ggaaataaat
     5701 acttttggaa ggcatggggt tgccagaacc acaaaaactg tgttgtatat ataatgtaaa
     5761 aattaagatg gggaaataat gagcatctgt gaataatgag gtgtcatttt tttttgataa
     5821 tcttgaatgg cagataaccc aatagcctgc ataccagaga catctgcgat ctctctctta
     5881 cttgaatagc cctgcagtct tctttttttt tttccttttt ttttctttaa tgtttacaat
     5941 tatccagttt tagaagagaa ggattttaac gccattgcct ggttacttgt tttatgctgt
     6001 aatctagttt attttatgta aaatgtatat tgaatgcttt cctttttata cctgccttaa
     6061 ataatttggc aatcagaatt aaaaaggttt tgttttgttt tttttttaat aa
//
