LOCUS       NM_029531               3863 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus zinc finger protein 60 (Zfp60), transcript variant 2,
            mRNA.
ACCESSION   NM_029531 XM_979639
VERSION     NM_029531.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3863)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3863)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   4  (bases 1 to 3863)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 3863)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 3863)
  AUTHORS   Ganss,B. and Kobayashi,H.
  TITLE     The zinc finger transcription factor Zfp60 is a negative regulator
            of cartilage differentiation
  JOURNAL   J Bone Miner Res 17 (12), 2151-2160 (2002)
   PUBMED   12469909
  REMARK    GeneRIF: role as negative regulator of cartilage differentiation
REFERENCE   7  (bases 1 to 3863)
  AUTHORS   Perez,M., Rompato,G., Corbi,N., De Gregorio,L., Dragani,T.A. and
            Passananti,C.
  TITLE     Zfp60, a mouse zinc finger gene expressed transiently during in
            vitro muscle differentiation
  JOURNAL   FEBS Lett 387 (2-3), 117-121 (1996)
   PUBMED   8674531
REFERENCE   8  (bases 1 to 3863)
  AUTHORS   Passananti,C., Felsani,A., Caruso,M. and Amati,P.
  TITLE     Mouse genes coding for 'zinc-finger'-containing proteins:
            characterization and expression in differentiated cells
  JOURNAL   Proc Natl Acad Sci U S A 86 (23), 9417-9421 (1989)
   PUBMED   2512579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK149305.1 and CAAA01066021.1.
            
            On or before May 4, 2006 this sequence version replaced
            XM_979639.1, NM_029531.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK149305.1, SRR1660819.78980.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2412              AK149305.1         22-2433
            2413-3863           CAAA01066021.1     25625-27075
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 15.97 cM"
     gene            1..3863
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /note="zinc finger protein 60"
                     /db_xref="GeneID:22718"
                     /db_xref="MGI:MGI:99207"
     exon            1..62
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            63..115
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..2197
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /note="zfp-60; zinc finger protein Mfg-3"
                     /codon_start=1
                     /product="zinc finger protein 60"
                     /protein_id="NP_083807.2"
                     /db_xref="CCDS:CCDS21030.1"
                     /db_xref="GeneID:22718"
                     /db_xref="MGI:MGI:99207"
                     /translation="MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIML
                     ETYSNLVAVVGRCIPKPDLIVLLEQEKEPWMAVKKETGRPSQGLETGFEAENRSPKNH
                     VYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTY
                     TSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSR
                     HQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFNRISTLFQHR
                     TIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENI
                     HTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHT
                     DEKPFKCKLCESAFRRKYQLSEHQRIHTDVKPYQCKDCGKFFRRRSNFTEHQSIHTGK
                     KPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTP
                     FECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFE
                     CKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCK
                     ECGKGFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSEC
                     GKYFTYGRDLKVHQSIHNLEKP"
     exon            116..242
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            243..341
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /inference="alignment:Splign:2.1.0"
     exon            342..3863
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3839..3844
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /note="hexamer: AATAAA"
     polyA_site      3863
                     /gene="Zfp60"
                     /gene_synonym="6330516O17Rik; Mfg-3; Mfg3"
                     /note="major polyA site"
ORIGIN      
        1 gcggacggtc gggtctttct ggtctgagta gggaattgct ttgtgtcttc ggtctctgca
       61 gagggaggaa gcctgaagaa gaatggccaa ctctagttct caacacatgg tctgtgggtc
      121 agtgacattt agggatgtgg ctgttgactt ctctcaggag gagtgggcct gcctggatgc
      181 tactcagaag gtcttataca ggaacataat gttggagacc tacagcaacc tggtcgcagt
      241 ggtgggacgt tgcattccca agccagatct gatcgtctta ctagagcagg agaaagagcc
      301 ctggatggct gtgaagaaag aaacaggcag gccgagccaa ggtttggaga caggttttga
      361 agctgaaaat agatctccaa agaatcatgt ttataataaa aagttaccca aacaaaccat
      421 acagcaatta agtaaaactt cggacgtcca gggcgtcagt gttagtaatg gccctggcta
      481 tagtgtaatc aaggagccac agaattatca agaaggagat gctaatcgaa atattactaa
      541 caagaaagaa atgtctactt acactagcaa gactcttgct cacaataaag aaaaaccgta
      601 taaatgtaaa gactgtggga agtgctttgg ttgtaagtca aaccttcatc agcatgagag
      661 tattcacact ggagagaagc cctatgaatg taaggactgt gggaagacct tcagactccc
      721 tcagatgctt tcaagacatc agaagtctca cagtgatgag agaccttttg agtgtaatat
      781 atgtggaaag tcttttcatc ttcctaccct gcttcagtac cataaaaata ttcatacagg
      841 tttaaaacca tttgaatgtg aggagtgtgg gaagtccttc aaccgcatct ctaccctttt
      901 tcagcatagg actattcatg ctggtatgaa accgtataaa tgtaatgtgt gtgggaaagc
      961 ctttaatcgt cgctcaaacc tcctgcaaca tcagaaaatt cattctgagg acagaccttt
     1021 tcattgtaag gtgtgtggaa aggccttcac tgtgctggct cagcttactc ggcacgagaa
     1081 cattcacact gaagacaaat cgtttgaatg taagcagtgt ggtaagatat ttagtaatgg
     1141 ctcttacctc ttacgacact acgatactca caccaatgag aaaccctttg agtgtaatat
     1201 atgtggcaag gcttttaggc ttcatctata cctttctgag catcagaaaa ctcacaccga
     1261 tgagaagcct ttcaagtgta agctgtgtga gtcagccttc agacgtaagt accagctcag
     1321 tgaacatcag agaattcaca ctgatgtgaa accctatcag tgcaaggatt gtgggaaatt
     1381 ctttcgtcga cgatcaaatt ttactgaaca tcagagtatt cacactggaa agaaaccctt
     1441 tgagtgtaag gactgtggga aggtctttag actaaatata catctcattc gacatcagag
     1501 atttcatagt gatgagaagc cctttgaatg taaagaatgt ggaaaggctt ttcatttttc
     1561 cagccagctt aataaccata aaaccagtca tacaggtcag acaccttttg aatgtaaaga
     1621 atgtgggaag tcgtttaagc gtgtctccag ccttgtggaa cataggatta ttcacagtgg
     1681 tgtgaaacca tataaatgta atgcgtgtgg aagagccttc aatcgtcgct caaacctcat
     1741 gcaacatgag aaaattcatt ctgatgagag accctttgag tgtaaggact gtggaaaggc
     1801 cttcactgtt ctggctcagc tcacacggca ccagacgatt cataatggaa agaaatcata
     1861 tgaatgtgag cagtgtgggt cagccttcag actcccgtac caactcactc aacatcagag
     1921 aattcattat gatgtgaagc catttcagtg caaggaatgt ggaaagggct ttgttcgtag
     1981 tacaggcctt agaattcatg aaaggatcca cactggtgag aagccctttc agtgtaagga
     2041 gtgtggagaa gcctttcagt atcattacca atttcttgga cactttagaa ttcatactgg
     2101 caagaaccct tatgaatgta gtgaatgtgg gaagtacttt acttatggtc gagaccttaa
     2161 agtacatcag agtattcaca atcttgagaa accgtaagaa tgtgggaaga ccttcagttg
     2221 aaaatcaaag gtggtttgac atgctaaact taatattatg aagaagaagc cttacaatgc
     2281 ttataaggaa tgtggaaagc cttcagtaat tctaagctac ctgtatatca gagaattcat
     2341 actggtctga agcactgttg atatgaaaat tgtgagaaag tttagattaa gttcagcctt
     2401 cagtgtacat caaagaattc atattggtct gaaaccccat cactgtaaag aatgtggaaa
     2461 gacccgcaac tgaagctcag gccttcagca taaaagtatc catgctgtcg tgaaacacta
     2521 tgcaaggagt gtgtaaacat ttatagaatt cattctgaaa actcatgaag gagtccatat
     2581 aggtctgaaa ccataaggat gtgaaaaaaa ttttattgtt aaatggtgag cttatacagc
     2641 atgagaaaag gaagacggat aagactttat ggaaatttta ctgaacatca aagaagtcat
     2701 taacaaactg ggactgaaag gagtctggga agaactttaa tctatcatag gatttaacca
     2761 acatctgagt gttcatatac ttgtgaacca aaaaatcctt agagaatgag agtgggaatt
     2821 ctgttcacag aaaatactgt tgagaaggac agaaagagat attgtagcct tcatgctcct
     2881 aagttagctc atctttaata ctactgttaa ttgcataagc ttaattcacc aaacacaatt
     2941 cagctcactt aggaagaaca gttattgaga ctattattat tcgaggcacc ttgccaccaa
     3001 ttacatccca tggctcctgt gctattacac tggatgtttg ctttctttct gcatagttca
     3061 tggtgagcac ggtaccaggc ggatgtgtgg aaacggggtc ataatggata gagaatcctt
     3121 gagagtattt ggtatgttct gtgaagtagc ttctacagtg ttggtgctct cacgggcgtt
     3181 actgtaacgg atatgaaaga caagctgtgt cgtagatagt ttagaaaagc ctcatgcagc
     3241 cctccagtat taaattctaa atatttcctt ctgggtaaaa tctaatagat gaacaggtac
     3301 atgaaagcat ttttattctc aatccgtttc tttagctttc gtgcagagat gtctataaac
     3361 tagctgttgg tgaataagta cttttaaacg gggataaaca catttaactt tcaaaagcta
     3421 aaatcctgta atttatgttc tctgcccaaa cattaagata aaatgcattt gtgactcagc
     3481 aggacagtgc agtcccctcc atctcatgct gctgagacca ttttaggttt gactagaatt
     3541 tgattttaga tggaggagat tcttggagat ttacccacct ctagtctgtg agccagcggt
     3601 caggatgctc ctgctatttt attttggctt ctcttagact gcctgcctgt gcaaactttc
     3661 cccttccact taactgctta ccctggcttc tgttaaactg cctgcttggg caaatgctcc
     3721 ccctgtagct gctgagcaag atatcagaat gtggttcttg tttttaatag ccccttgctg
     3781 taaatgcttg tgagtgtata tggatcccga ataaatgagt gtagtcccag ccaactggaa
     3841 taaagacttt cagttggcta taa
//
