LOCUS       NM_175477               4634 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus zinc finger protein 574 (Zfp574), transcript variant
            1, mRNA.
ACCESSION   NM_175477
VERSION     NM_175477.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4634)
  AUTHORS   Zhong,X., Moresco,J.J., SoRelle,J.A., Song,R., Jiang,Y.,
            Nguyen,M.T., Wang,J., Bu,C.H., Moresco,E.M.Y., Beutler,B. and
            Choi,J.H.
  TITLE     Disruption of the ZFP574-THAP12 complex suppresses B cell
            malignancies in mice
  JOURNAL   Proc Natl Acad Sci U S A 121 (31), e2409232121 (2024)
   PUBMED   39047044
  REMARK    GeneRIF: Disruption of the ZFP574-THAP12 complex suppresses B cell
            malignancies in mice.
REFERENCE   2  (bases 1 to 4634)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   3  (bases 1 to 4634)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125468.5, BY087218.1, BC059044.1 and AK143997.1.
            
            On Feb 16, 2018 this sequence version replaced NM_175477.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094354.1, AK042074.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-439               AC125468.5         185048-185486
            440-775             BY087218.1         2-337
            776-3623            BC059044.1         208-3055
            3624-4634           AK143997.1         3131-4141
FEATURES             Location/Qualifiers
     source          1..4634
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.73 cM"
     gene            1..4634
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /note="zinc finger protein 574"
                     /db_xref="GeneID:232976"
                     /db_xref="MGI:MGI:2442951"
     exon            1..676
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /inference="alignment:Splign:2.1.0"
     exon            677..4634
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /inference="alignment:Splign:2.1.0"
     CDS             697..3399
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /codon_start=1
                     /product="zinc finger protein 574"
                     /protein_id="NP_780686.1"
                     /db_xref="CCDS:CCDS20971.1"
                     /db_xref="GeneID:232976"
                     /db_xref="MGI:MGI:2442951"
                     /translation="MTEESEETVLYIEHRYVCSECNQLYGSLEEVLVHQNSHVPQQHF
                     ELVGVADPGVTVATEAASGTGLYQTLIQESQYQCLECGQLLLSPSQLLEHQELHLKMM
                     APQEAVPAKPPPKVPPLGSSAIHYECVDCKALFASQEMWLSHRQTHLRATPNKAPAPV
                     VLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGAAVPSVAATTEMVTEVELLLYKCSEC
                     SQLFQMPADFLEHQATHFPAPVPEAAEPATQQETQVPSPTEAAVSQPEPLPASDHSYE
                     LRNELRNGEAIGRDRRGRKPRRNNSGESGGAATQELFCSACDQLFLSPHQLQQHLRSH
                     REGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPN
                     PLHSCPCGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEEPAISFPEPAPAETGELEA
                     PELPVCEESSAEPAAPGSYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFK
                     KKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQS
                     STLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRL
                     LEVHQLVIHAGRQPYRCSSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSA
                     ARLQAHEAAHAAAGPGEVLAKEPPAPRASRATRTPVAPSPTALSGTTSAAPAAPARRR
                     GPECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPF
                     ACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAV
                     RQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEADGVQISG"
     regulatory      3600..3605
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /note="hexamer: AATAAA"
     polyA_site      3623
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /note="major polyA site"
     regulatory      4181..4186
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
                     /note="hexamer: AAGAAA"
     polyA_site      4208
                     /gene="Zfp574"
                     /gene_synonym="A630056B21Rik; Znf574"
ORIGIN      
        1 ggatccttga ctgtaacccg ccggcctcca gggctttgcg tgtctctaca gcctacactg
       61 cccgaatccc ctacgcctag cttgtcaggc gcccccaaga tggcgcctcc agcttcgtcc
      121 cgcctcccga cgtcatcgcg ccctctccgc tcagcgctcc cctttcgagc tatcaaaggc
      181 ggaatccgag aagaggtgga agaggaagaa cctccaggga ggattaaaga ggcgggtagt
      241 atccacctgg aggccgacca gcgagggaac attgctaaag gattggctgg gcgctgcgcg
      301 atcccacccc tccgctctat tggtcgaggc ttcaggaaac ctgagcatcg attggtctaa
      361 tgacaggggc agacagccga tgattgggcg aattgtgcag ttcttcgcag cggcccaggc
      421 ggaaggtggg aggagcgttg ttgagggcgg cctggggtga gagcgaggct gcggagcagg
      481 cgagacgacg ggcgctagag aggacgcggc gctagagtgg cggtgcaaag ggacctgaag
      541 cccgtagccc ggcctggggc cggcgagacg gccgaggcgg gtgagtcccc gccggagcgc
      601 agaggtccgg ccccacccgg cggcttgcct gcgtcattcg gcctgcacga tgaaggcctg
      661 aaggatcgcg tcccggccca gggccttgct gctgccatga ctgaggagag tgaagagacg
      721 gtcctgtaca ttgagcaccg ctatgtctgc tctgagtgca accagctcta tggatccttg
      781 gaggaggtgc ttgtgcacca gaactcccac gtgccccagc agcactttga gctggtgggc
      841 gtggctgacc ctggagtcac agtggccaca gaggctgctt caggcacagg cctatatcag
      901 accctcatcc aagagagcca gtaccagtgt cttgagtgtg ggcaactgct cctgtccccc
      961 agccagctcc tggagcacca ggagctacac ctgaagatga tggcaccgca ggaggcagtg
     1021 ccagccaagc caccacccaa ggtgcccccc ttgggctcca gcgccatcca ctatgagtgt
     1081 gtggactgta aggctctgtt cgccagccaa gagatgtggc ttagccatcg ccagacgcat
     1141 ctcagagcca cgcccaacaa ggctcctgct cctgtcgtct tggggtcccc agttgttttg
     1201 ggccctcctg tgggccaggc tcgagtggct gtggaacatt cataccgaaa agcagaagag
     1261 ggtggggagg gggcggccgt tccgtctgtg gccgccacca ccgagatggt gacagaagtg
     1321 gagctgctcc tctacaagtg ctccgagtgc tcccagctct tccagatgcc cgctgacttc
     1381 ctggagcacc aggccaccca cttccctgct cctgtcccgg aggctgcgga gcctgccaca
     1441 cagcaggaaa cccaggtccc ctcacccact gaggcagcag tgtctcagcc cgaacccctg
     1501 ccagcctctg atcacagtta tgagctgcgg aatgagctgc gaaatgggga ggccattggg
     1561 cgagaccgca ggggacggaa gccaaggagg aacaacagtg gagagtcagg tggggcggcc
     1621 acccaggaac tattttgctc tgcctgtgac cagctctttc tctcacccca ccagctacag
     1681 cagcaccttc ggagtcaccg ggagggtgtt tttaagtgtc ccctgtgcag tcgtgtcttc
     1741 cctagccctt ctagtctgga ccagcacctt ggtgaccata gcagtgagtc tcacttcctg
     1801 tgtgtagact gtggcctagc ctttggcacc gaagccctcc tcctggccca ccggcgagcc
     1861 cataccccga atcctctgca ttcgtgtccc tgtgggaaga cctttgttaa cctcaccaag
     1921 ttcctttatc accggcgtac ccacggagca ggaggtgtcc ctttgcccac aacaccagtt
     1981 ccaccagagg agcctgctat tagctttcct gagccagccc ctgcagagac cggagagcta
     2041 gaggccccag agctccccgt atgtgaggag agttcagccg agcctgcagc tccaggctct
     2101 taccgctgcc tcctgtgtag ccgggagttt ggtaaggcgt tgcagctgac ccggcaccag
     2161 cgttttgtgc accggctaga gcggcgccat aagtgcagca tttgtggcaa gatgttcaag
     2221 aagaagtctc atgtgcggaa ccatctgcgt acacacactg gggagcggcc cttcccctgc
     2281 cctgactgct ctaagccttt caactcacca gccaacctgg cccgccaccg gctcacacac
     2341 acgggggagc ggccctaccg gtgtggggac tgcggcaagg ccttcacgca gagctccact
     2401 ctgaggcagc atcgcctggt gcatgcccag cacttcccct accgctgcca ggagtgcgga
     2461 gtccgttttc accgccctta tcgcctgctc atgcaccgct accaccacac aggcgagtac
     2521 ccctacaagt gccgtgagtg cccccgttcc ttcttgctac gccggctgct agaggtccac
     2581 cagcttgtga tccatgctgg gcgccagccc taccgctgct catcctgtgg ggccgccttc
     2641 ccctcgtcac tgcggctccg tgagcatcgc tgcgcggccg ctgctgccca ggccccacgg
     2701 cgctttgagt gtgggacctg tggcaagaaa gtgggctctg ctgctcgcct gcaggcacat
     2761 gaagccgccc atgctgctgc gggtcctgga gaggtcttag ccaaggagcc tcctgctccc
     2821 cgggcctcga gagccactcg cacaccagtc gccccctccc cgacagccct cagtggtaca
     2881 acctctgctg cccctgcagc ccctgcccgg cgtcggggtc cggagtgcag tgagtgcaag
     2941 aagctcttca gcacagagac gtcactacag gtccatcggc gcatccacac aggtgagcgg
     3001 ccatacccct gtccagactg tggcaaggcc ttccgccaga gtacccatct gaaagaccac
     3061 agacgcctac acacaggcga gcggcccttt gcgtgtgaag tgtgtggcaa ggcctttgcc
     3121 atctccatgc gtctggcaga acatcgccgc atccacacgg gtgagcgacc ctactcctgt
     3181 cctgactgtg gcaagagcta ccgttccttc tccaatctct ggaagcaccg caagacccac
     3241 cagcagcaac accaggcggc cgtccgacag cagctggcag aggcggaggc tgctgtgggc
     3301 ctggctgtga tggaaactgc agtggaggct ctgccccttg tggaggccat tgagatctac
     3361 cctctagctg aagctgatgg ggtccagatc agtggctgac tggccccact ggtgctgaag
     3421 gccctccacc aaccccttta aacccgtgta catagtgtac ccctctcctc tccaccacct
     3481 tatgagttct gtaactaatt ttaactaatt tttttttgag ggggttgctc tggagtcctt
     3541 gatatgtaaa gggcacttcc cactttccac ctgtttggtg gtctccaaat gaagcagtca
     3601 ataaagactg aattggacat ttatgctttt tgtcaggcct agctatataa catgattcgg
     3661 aggatcatga ggccaggctg caatagagct gacttctggc tgcattccta gcaccccaga
     3721 tagaacttgg caggtagtcc agtttgctgg attgagaaga aggcagcctg agtctggggc
     3781 atggatcttt gaaaccagcc tcttgtggca gatgaaggta atgtgtcttg ccactagagg
     3841 tccccaaagc ctgaggaaaa tcttgaagca ctctgtggct ttggggcagg ggtggggcgt
     3901 gcaaacacat agagaaacat tggtgcactt ctcagcctgg ccatcccatt tccagcctga
     3961 tgtgggtcac atctgcgagg ccatccatct gtatttctca cactggatcc ctgaggacag
     4021 acttgtacca ggcgtaatgg ggaacagtgg cggaggggaa ctcctgggga ctctacctag
     4081 tagctgaatt tgaagttcta aatattgggg gctggagtag gaagtgactt gtcgtgtgtc
     4141 ccccatgccc ccaaccccaa gctgtatctc ggccaatagg aagaaagtga tggattggct
     4201 ggtcagtatc ttctagtata ttttgagtat ttcatcgcca ccccacctat acacacccta
     4261 agaactgcat atttgcttgg atctctcaca tgctgagcaa gctcaggacc acaaagctgt
     4321 gtcccgatat ctaattttga ggtcaggttt gctgattgtc caggcctcag actcactata
     4381 tcctaagcag gctttgagct tgttggtcct cctgccacag ccccttgagt agttaggatg
     4441 acaggcctgt gcccttgagt tattttgagt aacattggaa cttaacccta cagaggaggc
     4501 ctctggcatg tgactcggtg atggtcagtt caacccaagg cagagcttaa attcaaatct
     4561 ggtctccttt gatttaagca tccatattcc atgctgactg tcccatggtc tttcccaaca
     4621 agaaaatgga aatg
//
